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  1. Article ; Online: Chronic Painless Parotid Swelling.

    Kim, Ju Yeon / Park, Jin Kyun

    Journal of rheumatic diseases

    2022  Volume 28, Issue 3, Page(s) 171–172

    Language English
    Publishing date 2022-08-29
    Publishing country Korea (South)
    Document type Case Reports
    ISSN 2233-4718
    ISSN (online) 2233-4718
    DOI 10.4078/jrd.2021.28.3.171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: What rheumatologists need to know about mRNA vaccines: current status and future of mRNA vaccines in autoimmune inflammatory rheumatic diseases.

    Park, Jin Kyun / Lee, Eun Bong / Winthrop, Kevin L

    Annals of the rheumatic diseases

    2024  

    Abstract: Messenger RNA (mRNA) vaccines as a novel vaccine platform offer new tools to effectively combat both emerging and existing pathogens which were previously not possible. The 'plug and play' feature of mRNA vaccines enables swift design and production of ... ...

    Abstract Messenger RNA (mRNA) vaccines as a novel vaccine platform offer new tools to effectively combat both emerging and existing pathogens which were previously not possible. The 'plug and play' feature of mRNA vaccines enables swift design and production of vaccines targeting complex antigens and rapid incorporation of new vaccine constituents as needed. This feature makes them likely to be adopted for widespread clinical use in the future.Currently approved mRNA vaccines include only those against SARS-CoV-2 virus. These vaccines demonstrate robust immunogenicity and offer substantial protection against severe disease. Numerous mRNA vaccines against viral pathogens are in the early to late phase of development. Several mRNA vaccines for influenza are tested in clinical trials, with some already in phase 3 studies. Other vaccines in the early and late phases of development include those targeting
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/ard-2024-225492
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.114: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 167: Show issues

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  3. Article ; Online: Intrinsic contracture of the hands in sarcoid myopathy.

    Liew, Siew Khei / Park, Jin Kyun / Gong, Hyun Sik

    Journal of rheumatic diseases

    2023  Volume 30, Issue 3, Page(s) 204–207

    Abstract: Hand involvement in sarcoidosis is rare and it presents as tenosynovitis, dactylitis, nodules and osteoarticular bony destruction. We describe an unusual presentation of progressive intrinsic muscle contracture of both hands in a 42-year-old woman with ... ...

    Abstract Hand involvement in sarcoidosis is rare and it presents as tenosynovitis, dactylitis, nodules and osteoarticular bony destruction. We describe an unusual presentation of progressive intrinsic muscle contracture of both hands in a 42-year-old woman with sarcoid myopathy who presented with painful swelling and weakness of all four extremities. Her systemic symptoms improved with oral corticosteroids, but the hand muscle contracture remained after resolution of myositis. Serial soft tissue releases of intrinsic muscle contracture improved hand function markedly. This case highlights that surgery is a viable option to treat intrinsic muscle contracture in patients with chronic sarcoid myopathy complicated with severe muscle contracture.
    Language English
    Publishing date 2023-03-14
    Publishing country Korea (South)
    Document type Case Reports
    ISSN 2233-4718
    ISSN (online) 2233-4718
    DOI 10.4078/jrd.2023.0007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Response to: Correspondence on 'Current myositis clinical trials and tribulations' by Saygin

    Saygin, Didem / Werth, Victoria / Paik, Julie J / Park, Jin Kyun / Needham, Merrilee / Lundberg, Ingrid E / Christopher-Stine, Lisa

    Annals of the rheumatic diseases

    2024  

    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/ard-2024-225762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.114: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Zs.MO 167: Show issues

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  5. Article ; Online: Osteogenic Differentiation of Human Mesenchymal Stem Cells Modulated by Surface Manganese Chemistry in SLA Titanium Implants.

    Park, Jin-Woo / Tsutsumi, Yusuke / Park, Eui-Kyun

    BioMed research international

    2022  Volume 2022, Page(s) 5339090

    Abstract: The manganese (Mn) ion has recently been probed as a potential candidate element for the surface chemistry modification of titanium (Ti) implants in order to develop a more osteogenic surface with the expectation of taking advantage of its strong binding ...

    Abstract The manganese (Mn) ion has recently been probed as a potential candidate element for the surface chemistry modification of titanium (Ti) implants in order to develop a more osteogenic surface with the expectation of taking advantage of its strong binding affinity to the integrins on bone-forming cells. However, the exact mechanism of how Mn enhances osteogenesis when introduced into the surface of Ti implants is not clearly understood. This study investigated the corrosion resistance and potential osteogenic capacity of a Mn-incorporated Ti surface as determined by electrochemical measurement and examining the behaviors of human mesenchymal stem cells (MSCs) in a clinically available sandblasted/acid-etched (SLA) oral implant surface intended for future biomedical applications. The surface that resulted from wet chemical treatment exhibited the formation of a Mn-containing nanostructured TiO
    MeSH term(s) Cell Differentiation ; Humans ; Ions/metabolism ; Manganese/metabolism ; Mesenchymal Stem Cells/metabolism ; Osseointegration ; Osteogenesis ; Surface Properties ; Titanium/pharmacology
    Chemical Substances Ions ; Manganese (42Z2K6ZL8P) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2022-01-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2022/5339090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Controlled Molecular Arrangement of Cinnamic Acid in Layered Double Hydroxide through pi-pi Interaction for Controlled Release.

    Kim, Taeho / Paek, Seung-Min / Wang, Kang-Kyun / Park, Jin Kuen / Salles, Fabrice / Oh, Jae-Min

    International journal of molecular sciences

    2024  Volume 25, Issue 8

    Abstract: Cinnamic acid (CA) was successfully incorporated into Zn-Al layered double hydroxide (LDH) through coprecipitation. The CA moiety was stabilized in the interlayer space through not only electrostatic interaction but also intermolecular π-π interaction. ... ...

    Abstract Cinnamic acid (CA) was successfully incorporated into Zn-Al layered double hydroxide (LDH) through coprecipitation. The CA moiety was stabilized in the interlayer space through not only electrostatic interaction but also intermolecular π-π interaction. It was noteworthy that the CA arrangement was fairly independent of the charge density of LDH, showing the important role of the layer-CA and CA-CA interactions in molecular stabilization. Computer simulations using the Monte Carlo method as well as analytical approaches including infrared, UV-vis spectroscopy, and differential scanning calorimetry showed the existence of intermolecular interaction. In order to reinforce molecular stabilization, a neutral derivative of CA, cinnamaldehyde (CAD), was additionally incorporated into LDH. It was clearly shown that CAD played a role as a π-π interaction mediator to enhance the stabilization of CA. The time-dependent release of CA from LDH was first governed by the layer charge density of LDH; however, the existence of CAD provided additional stabilization to the CA arrangement to slow down the release kinetics.
    MeSH term(s) Cinnamates/chemistry ; Hydroxides/chemistry ; Delayed-Action Preparations/chemistry ; Acrolein/chemistry ; Acrolein/analogs & derivatives ; Kinetics ; Monte Carlo Method ; Calorimetry, Differential Scanning
    Chemical Substances cinnamic acid (140-10-3) ; Cinnamates ; Hydroxides ; Delayed-Action Preparations ; cinnamaldehyde (SR60A3XG0F) ; Acrolein (7864XYD3JJ)
    Language English
    Publishing date 2024-04-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25084506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Targeted Isolation of

    Kim, Jun Gu / Lee, Byeongsan / Han, Jae Sang / Oh, Taehoon / Park, Beomcheol / Cho, Yong Beom / An, Beom Kyun / Choi, Jin Won / Ko, Sung-Kyun / Lee, Mi Kyeong / Hong, Young-Soo / Hwang, Bang Yeon

    ACS omega

    2023  Volume 8, Issue 41, Page(s) 38263–38271

    Abstract: Liquid chromatography-mass spectrometry (LC-MS/MS)-based molecular networking analysis was applied ... ...

    Abstract Liquid chromatography-mass spectrometry (LC-MS/MS)-based molecular networking analysis was applied to
    Language English
    Publishing date 2023-10-06
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c04647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Phylogenetic Characteristics of Fasciola hepatica Isolated from a Korean Patient.

    Jeong, Mi Jin / Park, Jae Kyun / Yu, Hak Sun

    The Korean journal of parasitology

    2022  Volume 60, Issue 5, Page(s) 367–370

    Abstract: Fascioliasis is a parasitic infection caused by liver flukes. Although several cases have been reported in Korea, phylogenetic analysis of isolates is lacking. In this study, a 66-year-old woman with right upper quadrant (RUQ) abdominal pain was ... ...

    Abstract Fascioliasis is a parasitic infection caused by liver flukes. Although several cases have been reported in Korea, phylogenetic analysis of isolates is lacking. In this study, a 66-year-old woman with right upper quadrant (RUQ) abdominal pain was diagnosed as fascioliasis involving abdominal muscle by imaging study. She received praziquantel treatment, but symptoms were not improved. Lateral movement of the abscess lesion was followed. Trematode parasite was surgically removed from the patient's rectus abdominis muscle. The fluke was identified as Fasciola hepatica based on sequence analysis of 18S rDNA. To determine the phylogenetic position of this Fasciola strain (named Korean Fasciola 1; KF1), the cox1 gene (273 bp) was analyzed and compared with the genes of 17 F. hepatica strains isolated from cows, sheep, goats, and humans from various countries. Phylogenetic analysis showed that KF1 was closely related with the isolates from China goat.
    MeSH term(s) Female ; Humans ; Sheep ; Cattle ; Animals ; Aged ; Fasciola hepatica/genetics ; Fascioliasis/parasitology ; Phylogeny ; Fasciola/genetics ; DNA, Ribosomal/genetics ; Goats ; Sheep Diseases/parasitology
    Chemical Substances DNA, Ribosomal
    Language English
    Publishing date 2022-10-21
    Publishing country Korea (South)
    Document type Case Reports ; Journal Article
    ZDB-ID 286875-1
    ISSN 1738-0006 ; 0023-4001
    ISSN (online) 1738-0006
    ISSN 0023-4001
    DOI 10.3347/kjp.2022.60.5.367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3476: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Fever and Debilitating Myalgia.

    Ahn, Eun Young / Park, Jin Kyun

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

    2020  Volume 26, Issue 2, Page(s) e34

    MeSH term(s) Arteries/diagnostic imaging ; Extremities/blood supply ; Fever/diagnosis ; Fever/etiology ; Fluorodeoxyglucose F18/pharmacology ; Glucocorticoids/administration & dosage ; Humans ; Male ; Middle Aged ; Myalgia/diagnosis ; Myalgia/etiology ; Polyarteritis Nodosa/diagnosis ; Polyarteritis Nodosa/drug therapy ; Polyarteritis Nodosa/physiopathology ; Positron-Emission Tomography/methods ; Radiopharmaceuticals/pharmacology ; Treatment Outcome
    Chemical Substances Glucocorticoids ; Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2020-02-18
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1283266-2
    ISSN 1536-7355 ; 1076-1608
    ISSN (online) 1536-7355
    ISSN 1076-1608
    DOI 10.1097/RHU.0000000000000820
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4815: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Prolonged progression-free survival achieved by gemcitabine, cisplatin, and albumin-bound paclitaxel for the treatment of advanced biliary tract cancers.

    Choi, Jin Ho / Park, Hwanhee / Park, Joo Kyung / Lee, Jong Kyun / Lee, Kyu Taek / Lee, Kwang Hyuck

    Therapeutic advances in medical oncology

    2024  Volume 16, Page(s) 17588359231225045

    Abstract: Background: A regimen of gemcitabine, cisplatin, and nab-paclitaxel (GPA) has shown promising results in patients with advanced biliary tract cancer (aBTC).: Objectives: This study aimed to evaluate the benefit of GPA compared to a regimen of ... ...

    Abstract Background: A regimen of gemcitabine, cisplatin, and nab-paclitaxel (GPA) has shown promising results in patients with advanced biliary tract cancer (aBTC).
    Objectives: This study aimed to evaluate the benefit of GPA compared to a regimen of gemcitabine plus cisplatin (GP) in patients with aBTC.
    Design: Retrospective study.
    Methods: Patients with aBTC who received first-line chemotherapy with GPA or GP regimen at the Samsung Medical Center between July 2020 and June 2022 were included. The primary endpoint was progression-free survival (PFS).
    Results: In all, 37 patients were treated with GPA and 43 patients with GP. The GPA group showed significantly longer median PFS [12.0 months (95% CI, 7.2-16.8)] compared to the GP group [5.5 months (95% CI, 3.7-7.4;
    Conclusion: The GPA regimen improved the PFS of patients with aBTC compared to the GP regimen but showed no significant benefit in terms of OS after adjusting for confounding variables. Further large-scale studies are required to establish optimal indications for GPA.
    Language English
    Publishing date 2024-01-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2503443-1
    ISSN 1758-8359 ; 1758-8340
    ISSN (online) 1758-8359
    ISSN 1758-8340
    DOI 10.1177/17588359231225045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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