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  1. Book: Phantom plague

    Krishnan, Vidya

    how tuberculosis shaped history

    2022  

    Abstract: ... Plague, Vidya Krishnan, traces the history of tuberculosis from the slums of 19th-century New York ... to modern Mumbai. In a narrative spanning century, Krishnan shows how superstition and folk-remedies, made ...

    Title variant Phantom plague ; How tuberculosis shaped history
    Author's details Vidya Krishnan
    Abstract The definitive social history of tuberculosis, from its origins as a haunting mystery to its modern reemergence that now threatens populations around the world. It killed novelist George Orwell, Eleanor Roosevelt, and millions of others -- rich and poor. Desmond Tutu, Amitabh Bachchan, and Nelson Mandela survived it, just. For centuries, tuberculosis has ravaged cities and plagued the human body. In Phantom Plague, Vidya Krishnan, traces the history of tuberculosis from the slums of 19th-century New York to modern Mumbai. In a narrative spanning century, Krishnan shows how superstition and folk-remedies, made way for scientific understanding of TB, such that it was controlled and cured in the West. The cure was never available to black and brown nations. And the tuberculosis bacillus showed a remarkable ability to adapt -- so that at the very moment it could have been extinguished as a threat to humanity, it found a way back, aided by authoritarian government, toxic kindness of philanthropists, science denialism and medical apartheid. Krishnan's original reporting paints a granular portrait of the post-antibiotic era as a new, aggressive, drug resistant strain of TB takes over. Phantom Plague is an urgent, riveting and fascinating narrative that deftly exposes the weakest links in our battle against this ancient foe
    Language English
    Size viii, 300 Seiten, 22 cm
    Edition First edition
    Publisher Public Affairs
    Publishing place New York
    Publishing country United States
    Document type Book
    HBZ-ID HT021370387
    ISBN 978-1-5417-6846-8 ; 1-5417-6846-9
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Holding our breath: Exploring the causes of hypercapnic respiratory failure resulting in mortality.

    Krishnan, Vidya

    Respirology (Carlton, Vic.)

    2022  Volume 28, Issue 2, Page(s) 97–98

    MeSH term(s) Humans ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; Respiratory System ; Hypercapnia/complications ; Noninvasive Ventilation/methods
    Language English
    Publishing date 2022-11-27
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.14413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Debunking myths about daylight saving time: ten things everyone should know about the benefits of permanent standard time.

    Krishnan, Vidya / Johnson, Karin G

    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

    2023  Volume 19, Issue 9, Page(s) 1573–1576

    MeSH term(s) Humans ; Time
    Language English
    Publishing date 2023-05-22
    Publishing country United States
    Document type Editorial
    ZDB-ID 2397213-0
    ISSN 1550-9397 ; 1550-9389
    ISSN (online) 1550-9397
    ISSN 1550-9389
    DOI 10.5664/jcsm.10666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: COVID-19 and Home Positive Airway Pressure (PAP) Therapy.

    Krishnan, Vidya

    American journal of respiratory and critical care medicine

    2020  Volume 201, Issue 12, Page(s) P28–P29

    MeSH term(s) Betacoronavirus ; COVID-19 ; Continuous Positive Airway Pressure/instrumentation ; Continuous Positive Airway Pressure/methods ; Coronavirus Infections ; Disinfection/methods ; Humans ; Hypoventilation/therapy ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Sleep Apnea Syndromes/therapy
    Keywords covid19
    Language English
    Publishing date 2020-04-13
    Publishing country United States
    Document type Journal Article ; Patient Education Handout
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.2020C6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Tuberculosis: experts question evidence and safety data used to approve latest drug.

    Krishnan, Vidya

    BMJ (Clinical research ed.)

    2019  Volume 367, Page(s) l6832

    Language English
    Publishing date 2019-12-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.l6832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Transcriptional Landscape of Repetitive Elements in Psoriatic Skin from Large Cohort Studies: Relevance to Psoriasis Pathophysiology.

    Krishnan, Vidya S / Kõks, Sulev

    International journal of molecular sciences

    2023  Volume 24, Issue 23

    Abstract: While studies demonstrating the expression of repetitive elements (REs) in psoriatic skin using RNA-seq have been published before, not many studies have focused on the genome-wide expression patterns using larger cohorts. This study investigated the ... ...

    Abstract While studies demonstrating the expression of repetitive elements (REs) in psoriatic skin using RNA-seq have been published before, not many studies have focused on the genome-wide expression patterns using larger cohorts. This study investigated the transcriptional landscape of differentially expressed REs in lesional and non-lesional skin from two previously published large datasets. We observed significant differential expression of REs in lesional psoriatic skin as well as the skin of healthy controls. Significant downregulation of several ERVs, HERVs (including HERV-K) and LINEs was observed in lesional psoriatic skin from both datasets. The upregulation of a small subset of HERV-Ks and Alus in lesional psoriatic skin was also reported. An interesting finding from this expression data was the significant upregulation and overlapping of tRNA repetitive elements in lesional and non-lesional psoriatic skin. The data from this study indicate the potential role of REs in the immunopathogenesis of psoriasis. The expression data from the two independent large study cohorts are powerful enough to confidently verify the differential expression of REs in relation to psoriatic skin pathology. Further studies are warranted to understand the functional impact of these repetitive elements in psoriasis pathogenesis, thereby expanding their significance as a potential targeting pathway for the disease treatment of psoriasis and other inflammatory diseases.
    MeSH term(s) Humans ; Psoriasis/metabolism ; Repetitive Sequences, Nucleic Acid ; Down-Regulation ; Up-Regulation ; Cohort Studies
    Language English
    Publishing date 2023-11-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242316725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nurses' Perceptions of Intensive Care Unit Orientation Patient Education Pamphlet.

    Livingston, Daniel S / Krishnan, Vidya

    ATS scholar

    2023  Volume 4, Issue 3, Page(s) 332–343

    Abstract: Background: Critical illness is a stressful time for patients and their support networks. Although patient-directed educational material to improve the understanding of critical illness exists, both patients and staff members are often unaware of these ... ...

    Abstract Background: Critical illness is a stressful time for patients and their support networks. Although patient-directed educational material to improve the understanding of critical illness exists, both patients and staff members are often unaware of these resources or how to find them.
    Objectives: We aimed to evaluate the impact of the implementation of the American Thoracic Society's (ATS) "Managing the Intensive Care Unity (ICU) Experience: A Proactive Guide for Patients and Families", an ICU orientation pamphlet, on nurses' perceptions of the availability and effectiveness of patient and family educational resources.
    Methods: In a safety-net urban institution, we surveyed medical ICU (MICU) nurses in February 2021 regarding their perceptions of the availability of patient and family educational materials and the time and quality of communication with families of critically ill patients. We then introduced the MICU nurses to the ATS ICU orientation pamphlet to complement patient and family education. Quick response (QR) codes were created, linking to the online versions of the ICU pamphlet, and made available in waiting rooms. Printed copies of the pamphlet were provided to families in the ICU introductory packet upon patient MICU admission. We informed nurses regarding the pamphlet content, website, and QR codes. A postintervention survey was administered 11 months after the initial survey. Changes between pre and postintervention responses were analyzed for significant differences. Debriefing sessions with the MICU nurses were conducted, and subsequent discussions identified opportunities to improve the available educational resources.
    Results: At baseline, 28 of 67 (42%) MICU nurses responded to the survey. Although all nurses provided verbal education to patients and families, only 18% reported knowing about and using additional resources to supplement this education. The postintervention survey was completed by 39% of nurses; 39% of them reported using additional materials to supplement patient and family education. Reported awareness of the ATS ICU pamphlet increased from 4% before implementation to 23% after implementation (
    Conclusions: Informing nurses about the ICU pamphlet improved the acceptance and use of the materials, but it was still not accepted by many nurses. Barriers to ICU nurses using patient education resources should be explored to facilitate quality materials reaching patients and complementing patient communication. QR codes may have offered a way to disseminate educational materials to patients and families in a manner not previously considered. The process of evaluating the ICU pamphlet for our institution led to a broader discussion of additional needs for patient and family educational materials for our patient population. We encourage institutions to evaluate the sufficiency of their patient and family educational materials for similar local benefits.
    Language English
    Publishing date 2023-07-20
    Publishing country United States
    Document type Journal Article
    ISSN 2690-7097
    ISSN (online) 2690-7097
    DOI 10.34197/ats-scholar.2022-0142OC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Transcriptional Landscape of Repetitive Elements in Psoriatic Skin from Large Cohort Studies

    Vidya S. Krishnan / Sulev Kõks

    International Journal of Molecular Sciences, Vol 24, Iss 23, p

    Relevance to Psoriasis Pathophysiology

    2023  Volume 16725

    Abstract: While studies demonstrating the expression of repetitive elements (REs) in psoriatic skin using RNA-seq have been published before, not many studies have focused on the genome-wide expression patterns using larger cohorts. This study investigated the ... ...

    Abstract While studies demonstrating the expression of repetitive elements (REs) in psoriatic skin using RNA-seq have been published before, not many studies have focused on the genome-wide expression patterns using larger cohorts. This study investigated the transcriptional landscape of differentially expressed REs in lesional and non-lesional skin from two previously published large datasets. We observed significant differential expression of REs in lesional psoriatic skin as well as the skin of healthy controls. Significant downregulation of several ERVs, HERVs (including HERV-K) and LINEs was observed in lesional psoriatic skin from both datasets. The upregulation of a small subset of HERV-Ks and Alus in lesional psoriatic skin was also reported. An interesting finding from this expression data was the significant upregulation and overlapping of tRNA repetitive elements in lesional and non-lesional psoriatic skin. The data from this study indicate the potential role of REs in the immunopathogenesis of psoriasis. The expression data from the two independent large study cohorts are powerful enough to confidently verify the differential expression of REs in relation to psoriatic skin pathology. Further studies are warranted to understand the functional impact of these repetitive elements in psoriasis pathogenesis, thereby expanding their significance as a potential targeting pathway for the disease treatment of psoriasis and other inflammatory diseases.
    Keywords repetitive elements ; psoriasis ; HERV ; tRNA ; transcriptomics ; LINE-1 element ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 616
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Contextualizing global TB advocacy: Lessons from three experiments in movement building.

    Krishnan, Vidya

    Journal of clinical tuberculosis and other mycobacterial diseases

    2018  Volume 12, Page(s) 38–40

    Language English
    Publishing date 2018-06-19
    Publishing country England
    Document type Editorial
    ISSN 2405-5794
    ISSN (online) 2405-5794
    DOI 10.1016/j.jctube.2018.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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