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  1. Article ; Online: Reply to Filippo Alongi, Rosario Mazzola, Dario Aiello and Matteo Salgarello's Letter to the Editor re: Re: Daniel E. Spratt, Hebert A. Vargas, Zachary S. Zumsteg, et al. Patterns of Lymph Node Failure after Dose-escalated Radiotherapy: Implications for Extended Pelvic Lymph Node Coverage. Eur Urol 2017;71:37-43. A Step Forward in the Era of Functional Imaging?: Functional Imaging and Micrometastatic Disease: Implications for Radiotherapy Field Design.

    Spratt, Daniel E / Zelefsky, Michael J

    European urology

    2017  Volume 71, Issue 4, Page(s) e123–e124

    Language English
    Publishing date 2017-04
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2016.10.049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply to Pirus Ghadjar and Thomas Wiegel's Letter to the Editor re: Daniel E. Spratt, Robert T. Dess, Zachary S. Zumsteg, et al. A Systematic Review and Framework for the Use of Hormone Therapy with Salvage Radiation Therapy for Recurrent Prostate Cancer. Eur Urol 2018;73:156-65: Salvage Radiotherapy and Hormone Therapy: Change Is Coming, Just Not Quite Yet.

    Spratt, Daniel E / Dess, Robert T / Feng, Felix Y

    European urology

    2017  Volume 73, Issue 3, Page(s) e64–e65

    Language English
    Publishing date 2017-10-28
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2017.10.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reply to Leah Bensimon, Samy Suissa, and Laurent Azoulay's letter to the editor re: Daniel E. Spratt, Chi Zhang, Zachary S. Zumsteg, Xin Pei, Zhigang Zhang, Michael J. Zelefsky. metformin and prostate cancer: reduced development of castration-resistant disease and prostate cancer mortality. Eur Urol 2013;63:709-16.

    Spratt, Daniel E / Zhang, Zhigang / Zelefsky, Michael J

    European urology

    2013  Volume 64, Issue 2, Page(s) e29–30

    MeSH term(s) Androgen Antagonists/therapeutic use ; Humans ; Male ; Metformin/therapeutic use ; Orchiectomy/methods ; Prostatic Neoplasms/drug therapy
    Chemical Substances Androgen Antagonists ; Metformin (9100L32L2N)
    Language English
    Publishing date 2013-04-19
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2013.04.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The use of AI to identify predictive, pathology-based biomarkers in men with prostate cancer.

    Spratt, Daniel E

    Clinical advances in hematology & oncology : H&O

    2022  Volume 20, Issue 11, Page(s) 659–661

    MeSH term(s) Male ; Humans ; Prostatic Neoplasms/diagnosis ; Prostate-Specific Antigen ; Artificial Intelligence ; Biomarkers, Tumor
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77) ; Biomarkers, Tumor
    Language English
    Publishing date 2022-11-04
    Publishing country United States
    Document type Interview
    ZDB-ID 2271951-9
    ISSN 1543-0790
    ISSN 1543-0790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Optimizing Local Therapy for High-Risk Prostate Cancer: Evidence and Emerging Options

    Showalter, Timothy / Kishan, Amar / Hembree Culp, Stephen / Spratt, Daniel E. / Zaorsky, Nicholas

    2020  

    Keywords Medicine ; Oncology ; high risk prostate cancer ; androgen deprivation therapy ; radical prostatecomy ; recurrent prostate cancer ; radiation therapy
    Size 1 electronic resource (111 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230880
    ISBN 9782889661015 ; 2889661016
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: COVID-19 and Hypercoagulability: Potential Impact on Management with Oral Contraceptives, Estrogen Therapy and Pregnancy.

    Spratt, Daniel I / Buchsbaum, Rachel J

    Endocrinology

    2020  Volume 161, Issue 12

    MeSH term(s) Betacoronavirus/physiology ; COVID-19 ; Contraceptives, Oral, Hormonal/administration & dosage ; Contraceptives, Oral, Hormonal/adverse effects ; Coronavirus Infections/complications ; Coronavirus Infections/virology ; Estrogens/administration & dosage ; Estrogens/adverse effects ; Female ; Hormone Replacement Therapy/adverse effects ; Humans ; Male ; Pandemics ; Platelet Activation/drug effects ; Platelet Aggregation/drug effects ; Pneumonia, Viral/complications ; Pneumonia, Viral/virology ; Pregnancy ; Pregnancy Complications, Infectious/etiology ; Pregnancy Complications, Infectious/physiopathology ; SARS-CoV-2 ; Thrombophilia/etiology ; Thrombophilia/physiopathology
    Chemical Substances Contraceptives, Oral, Hormonal ; Estrogens
    Keywords covid19
    Language English
    Publishing date 2020-07-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 427856-2
    ISSN 1945-7170 ; 0013-7227
    ISSN (online) 1945-7170
    ISSN 0013-7227
    DOI 10.1210/endocr/bqaa121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Editorial Comment.

    Spratt, Daniel E

    The Journal of urology

    2020  Volume 204, Issue 1, Page(s) 89–90

    MeSH term(s) Humans ; Male ; Postoperative Period ; Prostatic Neoplasms ; Risk
    Language English
    Publishing date 2020-04-24
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000000774.02
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cancer Treatment Decision-Making During the COVID-19 Pandemic: Data Over Opinion.

    Spratt, Daniel E

    International journal of radiation oncology, biology, physics

    2020  Volume 108, Issue 2, Page(s) 338–339

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Male ; Pandemics ; Pneumonia, Viral ; Prostatic Neoplasms ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2020.07.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Efficacy of Sex Steroid Therapy Without Progestin or GnRH Agonist for Gonadal Suppression in Adult Transgender Patients.

    Pappas, India I / Craig, Wendy Y / Spratt, Lindsey V / Spratt, Daniel I

    The Journal of clinical endocrinology and metabolism

    2020  Volume 106, Issue 3, Page(s) e1290–e1300

    Abstract: Context: Testosterone (T) or estradiol (E2) are administered to suppress gonadal function in female-to-male (FTM) and male-to-female (MTF) transgender patients. How often sex steroids cause adequate suppression without GnRH agonist (GnRHa) or progestin ... ...

    Abstract Context: Testosterone (T) or estradiol (E2) are administered to suppress gonadal function in female-to-male (FTM) and male-to-female (MTF) transgender patients. How often sex steroids cause adequate suppression without GnRH agonist (GnRHa) or progestin therapy has not been reported.
    Objectives: (1) To determine how often T and E2 therapy alone can effectively suppress gonadal function in MTF and FTM transgender patients, and (2) to determine the frequency and range of serum E2 levels above the normal male range in FTM patients receiving T therapy.
    Design: Retrospective cohort study.
    Setting: Outpatient reproductive endocrinology clinic at an academic medical center.
    Patients: A total of 65 FTM and 33 MTF patients were included who were > 18 years of age and not receiving progestin or GnRHa therapy.
    Intervention: Female-to-male patients were receiving T through injections or gel. Male-to-female patients were receiving oral or subcutaneous E2.
    Main outcome measurements: In FTM patients the indicator of ovary suppression was amenorrhea. In MTF patients, the indicator of testes suppression was T levels <50 ng/dL.
    Results: Median serum total T level for FTM patients was 712 ng/dL (range, 370-1164 ng/dL). On T therapy alone, 90.8% of patients achieved amenorrhea and 49.2% of patients had serum E2 levels above the normal range for women. For MTF patients, the median serum E2 level was 129.2 pg/mL (range, 75-197 pg/mL). On E2 therapy alone, 84.8% of MTF patients had adequate suppression of testicular function.
    Conclusions: Testosterone and E2 therapy are usually effective without progestin or GnRHa therapy to suppress gonadal function in transgender patients. Progestin and/or GnRHa therapy should only be initiated in those patients who do not have adequate gonadal suppression on optimized doses of T or E2 alone.
    MeSH term(s) Adolescent ; Adult ; Cohort Studies ; Estradiol/administration & dosage ; Female ; Gonadal Steroid Hormones/therapeutic use ; Gonadotropin-Releasing Hormone/agonists ; Gonads/drug effects ; Gonads/physiology ; Hormone Replacement Therapy ; Humans ; Male ; Middle Aged ; Progestins/administration & dosage ; Retrospective Studies ; Sex Reassignment Procedures/methods ; Testosterone/administration & dosage ; Transsexualism/drug therapy ; Transsexualism/epidemiology ; Transsexualism/physiopathology ; Treatment Outcome ; United States/epidemiology ; Young Adult
    Chemical Substances Gonadal Steroid Hormones ; Progestins ; Gonadotropin-Releasing Hormone (33515-09-2) ; Testosterone (3XMK78S47O) ; Estradiol (4TI98Z838E)
    Language English
    Publishing date 2020-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgaa884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Introduction by the Guest Editor: The Rapidly Evolving Treatment Landscape of Prostate Cancer-The Convergence of Treatment Paradigms of Localized and Metastatic Diseases.

    Spratt, Daniel E

    Cancer journal (Sudbury, Mass.)

    2020  Volume 26, Issue 1, Page(s) 1

    MeSH term(s) Antineoplastic Agents/therapeutic use ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/genetics ; Chemotherapy, Adjuvant/methods ; Chemotherapy, Adjuvant/trends ; Conservative Treatment/methods ; Conservative Treatment/trends ; Humans ; Male ; Medical Oncology/methods ; Medical Oncology/trends ; Neoadjuvant Therapy/methods ; Neoadjuvant Therapy/trends ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/prevention & control ; Precision Medicine/methods ; Precision Medicine/trends ; Prostate/diagnostic imaging ; Prostate/pathology ; Prostate/surgery ; Prostatectomy/trends ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/therapy ; Radiosurgery/methods ; Radiosurgery/trends ; Treatment Outcome
    Chemical Substances Antineoplastic Agents ; Biomarkers, Tumor
    Language English
    Publishing date 2020-02-12
    Publishing country United States
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0000000000000431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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