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Article ; Online: Assessment of the antibacterial effect of Barium Titanate nanoparticles against

Kareem, Yasir Mohammed / Hamad, Thekra Ismael

2023 Volume 12, Page(s) 385

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Silicone Elastomers/chemistry ; Barium ; Staphylococcus epidermidis ; Anti-Bacterial Agents/pharmacology ; Nanoparticles
Chemical Substances	Silicone Elastomers ; Barium (24GP945V5T) ; Anti-Bacterial Agents
Language	English
Publishing date	2023-11-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.132727.2
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Article ; Online: Retraction Note: Culturomics and Amplicon-based Metagenomic Approaches for the Study of Fungal Population in Human Gut Microbiota.

Hamad, Ibrahim / Ranque, Stéphane / Azhar, Esam I / Yasir, Muhammad / Jiman-Fatani, Asif A / Tissot-Dupont, Hervé / Raoult, Didier / Bittar, Fadi

Scientific reports

2024 Volume 14, Issue 1, Page(s) 7771

Language	English
Publishing date	2024-04-02
Publishing country	England
Document type	Retraction of Publication
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-58471-3
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Article ; Online: Shifting Tides: Is It Time to Embrace Adjunctive Corticosteroids for Community-Acquired Pneumonia?

Hamad, Yasir / Bell, Taison D / Kadri, Sameer S

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

2023 Volume 77, Issue 12, Page(s) 1714–1716

MeSH term(s)	Humans ; Adrenal Cortex Hormones/therapeutic use ; Pneumonia/drug therapy ; Community-Acquired Infections/drug therapy ; Shock, Septic ; Sepsis
Chemical Substances	Adrenal Cortex Hormones
Language	English
Publishing date	2023-10-25
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	1099781-7
ISSN	1537-6591 ; 1058-4838
ISSN (online)	1537-6591
ISSN	1058-4838
DOI	10.1093/cid/ciad498
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Article: Outcomes of Ceftriaxone Compared With Cefazolin or Nafcillin/Oxacillin for Outpatient Therapy for Methicillin-Sensitive

Hamad, Yasir / Nickel, Katelin B / Olsen, Margaret A / George, Ige A

Open forum infectious diseases

2024 Volume 11, Issue 2, Page(s) ofad662

Abstract: Background: Ceftriaxone is a convenient option for methicillin-sensitive : Methods: In this retrospective cohort, a large insurance claims database was queried from 2010 to 2018 for adults with MSSA bloodstream infection (BSI). Patients discharged on ...

Abstract	Background: Ceftriaxone is a convenient option for methicillin-sensitive Methods: In this retrospective cohort, a large insurance claims database was queried from 2010 to 2018 for adults with MSSA bloodstream infection (BSI). Patients discharged on OPAT on cefazolin or oxacillin/nafcillin were compared with ceftriaxone with respect to 90-day hospital readmission with the same infection category and 90-day all-cause readmission using logistic regression models. Results: Of 1895 patients with MSSA BSI, 1435 (75.7%) patients received cefazolin, oxacillin, or nafcillin and 460 (24.3%) ceftriaxone. Readmission due to the same infection category occurred in 366 (19.3%), and all-cause readmission occurred in 535 (28.3%) within 90 days. Risk factors significantly associated with readmission with the same infection category were the oldest sampled age group (61-64 years: adjusted odds ratio [aOR], 1.47 [95% confidence interval {CI}, 1.01-2.14]), intensive care unit stay during index admission (aOR, 2.33 [95% CI, 1.81-3.01]), prosthetic joint infection (aOR, 1.96 [95% CI, 1.18-2.23]), central line-associated BSI (aOR, 1.72 [95% CI, 1.33-2.94]), and endocarditis (aOR, 1.63 [95% CI, 1.18-2.23]). Ceftriaxone was not associated with increased risk of readmission with the same infection category (aOR, 0.89 [95% CI, .67-1.18]), or 90-day all-cause readmission (aOR, 0.86 [95% CI, .66-1.10]) when compared with oxacillin/nafcillin/cefazolin. Conclusions: In this cohort of MSSA BSI patients discharged on OPAT, there were no differences in outcomes of readmission with the same infection and 90-day all-cause readmission in patients treated with ceftriaxone compared to oxacillin/nafcillin or cefazolin. Patients with complicated BSIs such as endocarditis and epidural abscess were more likely to be prescribed cefazolin or oxacillin/nafcillin.
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Clinical Trial
ZDB-ID	2757767-3
ISSN	2328-8957
ISSN	2328-8957
DOI	10.1093/ofid/ofad662
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Article ; Online: Assessment of the antibacterial effect of Barium Titanate nanoparticles against Staphylococcus epidermidis adhesion after addition to maxillofacial silicone [version 2; peer review

Thekra Ismael Hamad / Yasir Mohammed Kareem

F1000Research, Vol

2 approved, 1 approved with reservations]

2023 Volume 12

Abstract: Background: Maxillofacial silicones are the most popular and acceptable material for making maxillofacial prostheses, but they are not perfect in every sense. To enhance their effectiveness, more improvements to their properties are required, such as ... ...

Abstract	Background: Maxillofacial silicones are the most popular and acceptable material for making maxillofacial prostheses, but they are not perfect in every sense. To enhance their effectiveness, more improvements to their properties are required, such as their antimicrobial efficiency. This study assess the antibacterial effect of barium titanate nanoparticles in various percentages against staphylococcus epidermidis biofilm adhesion after addition to maxillofacial silicone. Methods: Barium titanate nanoparticles were added into VST-50 platinum silicone elastomer in four weight percentages (0.25wt%, 0.5wt%, 0.75wt% and 1wt%). 50 specimens were prepared and categorized into five groups; one control group and four experimental groups. All conducted data was statistically analyzed using (one-way ANOVA) analysis of variance, and Games-Howell multiple comparison test (significant level at p < 0.05). Shapiro-Wilk and Levene’s tests were used, respectively, to evaluate the normal distribution and homogeneity of the data. Result: One-way ANOVA test revealed a highly significant difference between all groups, and Games-Howell test revealed a highly significant difference between the control group and the four experimental groups. The 0.25wt% and 0.5wt% groups revealed a highly significant difference between them and with the (0.75%wt and 0.1%wt) groups. While the 0.75wt% group revealed a significant difference with 1wt% group. Conclusions: The addition of barium titanate to VST-50 maxillofacial silicone enhanced the antibacterial activity of silicon against Staphylococcus epidermidis, and this activity seems to be concentration dependent. FTIR analysis demonstrated no chemical interaction between the Barium Titanate and the VST-50 maxillofacial silicone elastomer. SEM pictures show that the barium titanate nanopowder was effectively dispersed inside the maxillofacial silicone matrix.
Keywords	barium titanate (BaTiO3) ; VST-50 silicone elastomer ; bacterial adhesion ; Staphylococcus epidermidis ; eng ; Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	F1000 Research Ltd
Document type	Article ; Online
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Article ; Online: Lactulose vs Lactuloseand inulin in treatment of pediatric constipation

Salar Sabah Berdawd, / Sasan Loqa Hanna, / Yasir Kakameen Hamad

Diyala Journal of Medicine, Vol 24, Iss

2023 Volume 1

Abstract: Background: Assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group. Objective: To assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group. ... ...

Abstract	Background: Assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group. Objective: To assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group. Patients and Methods: One hundred forty-six patients with fuctionalconstipation were chosen in a non-randomized superiority trial manner as they were convenient to enroll due to their presentation to the outpatient clinic during the period from August 2019 to February 2022.Patient received either a solution of lactulose 3.3g/5ml in group A or a solution of 4.005g Inulin fiber and 4.005g lactulose per 20ml in group B. Results: Total of 146 children were included; all, 146 patients completed the study. In the lactulose group, 19 patients were on therapy for less than 6 months, and 48 were on therapy for more than 6 months. In the lactulose + fiber group, 59 patients were on therapy for less than 6 months, and 20 were on therapy for more than 6 months. No serious adverse effects were registered but 18 (27%) of children in the lactulose group encountered side effects, while 11 (14%) of children in the lactulose + fiber group encountered side effects. Conclusion: A solution of Lactulose + fiber is superior to a solution of Lactulose alone in terms of efficacy for the treatment of constipation in the pediatric age group. It also has a lower side effects profile.
Keywords	Abdominal pain ; bloating ; constipation ; distension ; lactulose ; inulin ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	College of medicine/ University of Diyala
Document type	Article ; Online
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Article: ASSOCIATION BETWEEN H. PYLORI INFECTION AND IRRITABLE BOWEL SYNDROME.

Hamad, Ammar Jabbar / Alnaji, Esraa K / Almohana, Sadiq Jebar / Kareem, Yasir Shakir / Albdairi, Aseel Jassim

Wiadomosci lekarskie (Warsaw, Poland : 1960)

2023 Volume 76, Issue 2, Page(s) 406–414

Abstract: Objective: 1 UNIVERSITY OF KUFA, AL.-NAJAF, IRAQ 2ALSADER TEACHING HOSPITAL, AL!NAJAF, IRAQ The aim: To research the association of H. pylori infection in patients with irritable bowel syndrome.: Patients and methods: Materials and method: In this ... ...

Abstract	Objective: 1 UNIVERSITY OF KUFA, AL.-NAJAF, IRAQ 2ALSADER TEACHING HOSPITAL, AL!NAJAF, IRAQ The aim: To research the association of H. pylori infection in patients with irritable bowel syndrome. Patients and methods: Materials and method: In this case control study, 43 patients with IBS (13 males and 30 females) diagnosed according to Rome IV criteria and other 43 controls where included, the patients and control are matched to the gender and age which ranged from 18 to55 years, the study groups were referred to perform a stool antigen test for H. pylori. Results: Results: Presence of H. pylori was compared between patients with IBS and controls using chi-square test. There was significant correlation between the presence of H. pylori and IBS, chi-square = 4.09, P-value = 0.043. The odd ratio for patients with H. pylori to have IBS was 2.53 (95% confidence interval: 1.02- 6.29). There is no signi"cant relationship between type of IBS and presence of H. pylori, chi-square = 2.87, P-value = 0.238. There is no significant relationship between the presence of H. pylori and age, BMI, gender, occupation, or marital state. Conclusion: Conclusions: Results of our study had shown an association of H. pylori infection in patients with IBS, which may propose a link of this infection in IBS pathophysiology.
MeSH term(s)	Male ; Female ; Humans ; Adolescent ; Irritable Bowel Syndrome/complications ; Irritable Bowel Syndrome/epidemiology ; Helicobacter pylori ; Case-Control Studies ; Feces ; Helicobacter Infections/complications
Language	English
Publishing date	2023-04-03
Publishing country	Poland
Document type	Journal Article
ZDB-ID	414731-5
ISSN	0043-5147 ; 1895-0485 ; 0860-8865
ISSN	0043-5147 ; 1895-0485 ; 0860-8865
DOI	10.36740/WLek202302123
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Article ; Online: Black Hairy Tongue.

Hamad, Yasir / Warren, David K

The New England journal of medicine

2018 Volume 379, Issue 10, Page(s) e16

MeSH term(s)	Anti-Bacterial Agents/adverse effects ; Female ; Humans ; Middle Aged ; Minocycline/adverse effects ; Tongue/pathology ; Tongue, Hairy/chemically induced ; Tongue, Hairy/pathology
Chemical Substances	Anti-Bacterial Agents ; Minocycline (FYY3R43WGO)
Language	English
Publishing date	2018-09-04
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	207154-x
ISSN	1533-4406 ; 0028-4793
ISSN (online)	1533-4406
ISSN	0028-4793
DOI	10.1056/NEJMicm1800351
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Article ; Online: Prevalence and risk factors associated with readmission with acute kidney injury in patients receiving vancomycin outpatient parenteral antimicrobial therapy.

Hamad, Yasir / Nickel, Katelin B / Burnett, Yvonne J / Hamad, Tarig / George, Ige A / Olsen, Margaret A

Journal of clinical pharmacy and therapeutics

2022 Volume 47, Issue 12, Page(s) 2188–2195

Abstract: Introduction: Vancomycin is commonly used during outpatient parenteral antimicrobial therapy (OPAT). Therapeutic drug monitoring (TDM) of vancomycin is recommended to ensure effective and safe therapy, as use has been associated with acute kidney injury ...

Abstract	Introduction: Vancomycin is commonly used during outpatient parenteral antimicrobial therapy (OPAT). Therapeutic drug monitoring (TDM) of vancomycin is recommended to ensure effective and safe therapy, as use has been associated with acute kidney injury (AKI). Methods: The MarketScan® Commercial Database was queried from 2010 to 2016 to identify patients aged 18-64 years discharged from an inpatient hospitalization on vancomycin OPAT. The primary endpoint was hospital readmission with AKI within 6 weeks of index hospital discharge. TDM was defined as at least one vancomycin level obtained during outpatient therapy. Bivariate analysis was used to examine associations with outcomes; significant factors were incorporated into a multivariable logistic regression model. Results: A total of 14,196 patients were included in the study; median age was 54 years and 53.8% were male. Readmission with AKI occurred in 385 (2.7%) and was independently associated with chronic kidney disease (aOR 2.63 [95%CI 1.96-3.52]), congestive heart failure (1.81 [1.34-2.44]), chronic liver disease (1.74 [1.17-2.59]), hypertension (1.73 [1.39-2.17]), septicemia (1.61 [1.30-2.00]), and concomitant OPAT with IV penicillins (1.73 [1.21-2.49]) while skin and soft tissue infection (0.67 [0.54-0.83]) and surgical site infection (0.74 [0.59-0.93]) were associated with lower risk of readmission with AKI. TDM was not associated with lower risk of readmission with AKI. Conclusion: Chronic kidney disease, congestive heart failure, hypertension, chronic liver disease, septicemia, and concomitant OPAT with IV penicillins were significantly associated with higher risk of readmission with AKI during vancomycin OPAT.
MeSH term(s)	Humans ; Male ; Middle Aged ; Female ; Vancomycin/adverse effects ; Anti-Bacterial Agents/adverse effects ; Outpatients ; Patient Readmission ; Prevalence ; Retrospective Studies ; Anti-Infective Agents ; Acute Kidney Injury/chemically induced ; Acute Kidney Injury/epidemiology ; Risk Factors ; Penicillins ; Sepsis/drug therapy ; Hypertension/drug therapy ; Heart Failure/drug therapy ; Renal Insufficiency, Chronic/chemically induced
Chemical Substances	Vancomycin (6Q205EH1VU) ; Anti-Bacterial Agents ; Anti-Infective Agents ; Penicillins
Language	English
Publishing date	2022-10-18
Publishing country	England
Document type	Journal Article
ZDB-ID	639006-7
ISSN	1365-2710 ; 0269-4727
ISSN (online)	1365-2710
ISSN	0269-4727
DOI	10.1111/jcpt.13790
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Article ; Online: COVID-19 and Outpatient Parenteral Antimicrobial Therapy.

Hamad, Yasir / Joynt-Maddox, Karen E / Powderly, William G

Annals of internal medicine

2020 Volume 174, Issue 1, Page(s) 142

MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents ; COVID-19 ; Humans ; Outpatients ; SARS-CoV-2
Chemical Substances	Anti-Bacterial Agents ; Anti-Infective Agents
Language	English
Publishing date	2020-11-08
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	336-0
ISSN	1539-3704 ; 0003-4819
ISSN (online)	1539-3704
ISSN	0003-4819
DOI	10.7326/L20-1347
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