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  1. Article ; Online: Rhizobium radiobacter

    Roy, Sasmit / Basuli, Debargha / Rahman, Ebad U / Adapa, Sreedhar / Reddy, Sohil N

    Journal of medical cases

    2022  Volume 13, Issue 9, Page(s) 471–474

    Abstract: Rhizobium ... ...

    Abstract Rhizobium radiobacter
    Language English
    Publishing date 2022-09-28
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2586383-6
    ISSN 1923-4163 ; 1923-4163
    ISSN (online) 1923-4163
    ISSN 1923-4163
    DOI 10.14740/jmc3999
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Brevibacterium casei

    Roy, Sasmit / Garcha, Amarinder S / Patel, Sumit S / Rahman, Ebad / Adapa, Sreedhar

    Journal of community hospital internal medicine perspectives

    2022  Volume 12, Issue 1, Page(s) 64–67

    Abstract: Brevibacterium ... ...

    Abstract Brevibacterium casei
    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2616884-4
    ISSN 2000-9666
    ISSN 2000-9666
    DOI 10.55729/2000-9666.1012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Emerging Uncommon Non-Albicans Candida: Candida Parapsilosis Peritonitis in a Peritoneal Dialysis Patient.

    Roy, Sasmit / Vantipalli, Praveena / Garcha, Amarinder / Pokal, Mytri / Adapa, Sreedhar

    Cureus

    2021  Volume 13, Issue 8, Page(s) e17083

    Abstract: ... Candida ... ...

    Abstract Candida parapsilosis
    Language English
    Publishing date 2021-08-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.17083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Incidental detection of operational tolerance in a deceased donor kidney transplant recipient lost to follow-up for more than 10 years: A case report and literature review.

    Roy, Sasmit / Chowdhury, Monzurul Hasan / Basuli, Debargha / Adapa, Sreedhar / Bodziak, Kenneth

    Clinical nephrology. Case studies

    2023  Volume 11, Page(s) 12–16

    Abstract: Graft tolerance is a clinical state of absence of an immune response in the recipient toward a donor allograft without any exogenous immunosuppression. Although more prevalent in liver transplantation recipients, it has rarely been reported in renal ... ...

    Abstract Graft tolerance is a clinical state of absence of an immune response in the recipient toward a donor allograft without any exogenous immunosuppression. Although more prevalent in liver transplantation recipients, it has rarely been reported in renal transplant recipients. We present a 62-year-old deceased donor kidney transplant recipient who exhibited operational tolerance as they stopped immunosuppressant medications for more than 10 years and yet demonstrated stable graft function. Although various hypotheses, such as deletion, anergy, immunoregulation, and clonal exhaustion, have been experimentally validated, clinical "operational tolerance" of a renal allograft on a prolonged basis has been infrequently reported in the medical literature. This review intends to highlight possible etiologies and make clinicians aware of this possible rare condition to which more research is needed.
    Language English
    Publishing date 2023-02-16
    Publishing country Germany
    Document type Case Reports
    ISSN 2196-5293
    ISSN (online) 2196-5293
    DOI 10.5414/CNCS111030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Megadose Vitamin C Prescription Through Alternative Medicine Leading to End-Stage Renal Disease: Case Study and Literature Review.

    Roy, Sasmit / Chourasia, Prabal / Sangani, Vikram / Errabelli, Praveen Kumar / Patel, Sumit S / Adapa, Sreedhar

    Journal of investigative medicine high impact case reports

    2023  Volume 11, Page(s) 23247096231158954

    Abstract: Modern medicine has made tremendous advancements and succeeded in increasing longevity through adequate screening and diagnosis and various new therapeutic approaches. However, alternative medicine is a branch of health care practicing different ... ...

    Abstract Modern medicine has made tremendous advancements and succeeded in increasing longevity through adequate screening and diagnosis and various new therapeutic approaches. However, alternative medicine is a branch of health care practicing different traditional and unconventional, potentially hazardous therapies to treat commonly known ailments. Standard low-dose vitamin C, ie, 500-1000 mg, is approved in medical conditions like methemoglobinemia, scurvy, burns and also helps iron absorption in anemia. However, toxic doses carry high nephrotoxicity potential like in our case. We present a 74-year-old Caucasian female falling victim to one such alternative therapy leading to acute kidney injury requiring lifelong hemodialysis. She had endometrial cancer and received 100 gm of intravenous vitamin C weekly through a provider for the last 6 weeks as part of this alternate approach to cure her cancer. Upon admission, the serum creatinine level was elevated at 8.2 mg/dl, which subsequently did not improve with conservative management. Renal biopsy revealed diffuse acute tubular injury with polarized microscopy demonstrating calcium oxalate crystals. While her blood vitamin C levels were high, the serum oxalate level was normal. She ended up requiring renal replacement therapy permanently. Alternative medicine continues to be a significant health care hazard with the potential to cause unwanted irreversible nephrotoxicity. Public attention is necessary at various social levels to counter the detrimental outcomes of alternative medicine.
    MeSH term(s) Female ; Humans ; Aged ; Ascorbic Acid/adverse effects ; Hyperoxaluria ; Vitamins/adverse effects ; Kidney Failure, Chronic/therapy ; Complementary Therapies
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R) ; Vitamins
    Language English
    Publishing date 2023-03-11
    Publishing country United States
    Document type Review ; Journal Article ; Case Reports
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/23247096231158954
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: An Uncommon Presentation of Vasopressin-Induced Purpura Fulminans.

    Awad, Vanessa / Nair, Preeth / Roy, Sasmit / Yalamanchili, Anish / Adapa, Sreedhar / Vemuri, Nirupama

    Journal of medical cases

    2023  Volume 14, Issue 4, Page(s) 130–136

    Abstract: Purpura fulminans (PF) is a rarely encountered rapidly evolving dermatological manifestation of ischemia, particularly in critically ill patients. Considered one of the very few dermatological emergencies, it has high mortality rate where patients often ... ...

    Abstract Purpura fulminans (PF) is a rarely encountered rapidly evolving dermatological manifestation of ischemia, particularly in critically ill patients. Considered one of the very few dermatological emergencies, it has high mortality rate where patients often succumb to the illness. It can manifest in three forms: neonatal, idiopathic, and the more commonly infectious variety, which can be secondary to mostly bacterial and rarely viral etiology. It is also reported to be highly associated with disseminated intravascular coagulation (DIC), heparin-induced thrombocytopenia (HIT), and acute hepatic failure (AHF). Hereditary or acquired deficiency of protein C and dysregulation of the coagulation cascade, mainly protein C-thrombomodulin, has been implicated in the pathogenesis. We present a 55-year-old male admitted to the intensive care unit for diabetic ketoacidosis (DKA) and septic shock. Along with initiating management protocol for DKA and broad-spectrum antibiotics, he was initially started on norepinephrine for septic shock. Because of persistent refractory septic shock, he was subsequently initiated on phenylephrine and vasopressin to maintain adequate perfusion. The following day, he was found to have sharply demarcated blackish non-blanching discoloration on bilateral knees, lower limbs, and scrotum, sparing the acral regions. This cutaneous manifestation persisted throughout his hospital course, although it improved after discontinuation of vasopressin while continuing with other pressors. Vasopressin has been implicated in a few instances of skin necrosis; however, PF has rarely been documented and never within 1 day like ours. This case demonstrates a unique development of PF likely from vasopressin after ruling out the diagnoses of DIC, HIT, thrombotic thrombocytopenic purpura, and AHF.
    Language English
    Publishing date 2023-04-30
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2586383-6
    ISSN 1923-4163 ; 1923-4163
    ISSN (online) 1923-4163
    ISSN 1923-4163
    DOI 10.14740/jmc4062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The Role of Patiromer in Delaying the Onset of Renal Replacement Therapy in Patients with Advanced Renal Failure.

    Wadhwa, Nand K / Kline, Jason A / Adapa, Sreedhar R

    Case reports in nephrology

    2021  Volume 2021, Page(s) 6987456

    Abstract: Patients with chronic kidney disease (CKD) are at an increased risk of developing hyperkalemia, which can be potentially life threatening. Hyperkalemia is frequently encountered with renin-angiotensin-aldosterone system inhibitor (RAASi) therapy use in ... ...

    Abstract Patients with chronic kidney disease (CKD) are at an increased risk of developing hyperkalemia, which can be potentially life threatening. Hyperkalemia is frequently encountered with renin-angiotensin-aldosterone system inhibitor (RAASi) therapy use in patients with CKD and often results in the underdosing or discontinuation of these drugs. RAASi therapy has been proven to delay the progression of CKD, ameliorate proteinuria, and reduce the overall risk of cardiovascular morbidity and mortality. Patiromer is a sodium-free, potassium-binding polymer used for the treatment of hyperkalemia. We present a case series of four patients with Stage 4 or 5 CKD in whom the initiation of dialysis was delayed with the use of patiromer. For one patient, dialysis was delayed by 18 months, whereas the remaining three patients, in whom hyperkalemia was one of the main complications, remain dialysis independent to date.
    Language English
    Publishing date 2021-09-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627652-5
    ISSN 2090-665X ; 2090-6641
    ISSN (online) 2090-665X
    ISSN 2090-6641
    DOI 10.1155/2021/6987456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Hepatitis B-Associated Lupus-Like Glomerulonephritis Successfully Treated With Antiretroviral Drugs and Prednisone: A Case Report and Literature Review.

    Roy, Sasmit / Gupta, Rohan / Adapa, Sreedhar / Bose, Subhashish / Garcha, Amarinder

    Journal of investigative medicine high impact case reports

    2022  Volume 10, Page(s) 23247096221086451

    Abstract: Kidney involvement with hepatitis B virus is varied and mostly limited to nephrotic syndrome with membranous nephropathy and nephritic syndrome with membranous proliferative glomerulonephritis. Lupus nephritis is associated with nephritic or nephrotic ... ...

    Abstract Kidney involvement with hepatitis B virus is varied and mostly limited to nephrotic syndrome with membranous nephropathy and nephritic syndrome with membranous proliferative glomerulonephritis. Lupus nephritis is associated with nephritic or nephrotic range proteinuria with most common finding of sub-endothelial electron-dense deposits and immunological stain demonstrating full-house picture with all immunological marker staining. Our case discusses a young male patient presenting with rapidly worsening renal function along with proteinuria, found to be positive for both hepatitis B core antibody along with hepatitis B surface antibody plus positive anti-neutrophilic antibody but negative anti-double-stranded DNA. Kidney biopsy demonstrated hepatitis B-associated lupus-like glomerulonephritis. He responded successfully with antiretroviral therapy and high-dose prednisone. Patient did not need lupus-specific treatment and recovered with antiretroviral therapy only. Hepatitis B-associated lupus-like glomerulonephritis has rarely been reported and possess a diagnostic and therapeutic challenge to all nephrologists.
    MeSH term(s) Anti-Retroviral Agents/therapeutic use ; Female ; Glomerulonephritis/drug therapy ; Glomerulonephritis/etiology ; Glomerulonephritis/pathology ; Glomerulonephritis, Membranous ; Hepatitis B/complications ; Hepatitis B/drug therapy ; Humans ; Lupus Nephritis/complications ; Lupus Nephritis/drug therapy ; Lupus Nephritis/pathology ; Male ; Prednisone/therapeutic use ; Proteinuria/etiology
    Chemical Substances Anti-Retroviral Agents ; Prednisone (VB0R961HZT)
    Language English
    Publishing date 2022-05-02
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/23247096221086451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Roseomonas mucosa

    Roy, Sasmit / Patel, Sumit / Kummamuru, Hardhik / Garcha, Amarinder Singh / Gupta, Rohan / Adapa, Sreedhar

    Case reports in nephrology

    2021  Volume 2021, Page(s) 1979332

    Abstract: ... ...

    Abstract Roseomonas
    Language English
    Publishing date 2021-11-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627652-5
    ISSN 2090-665X ; 2090-6641
    ISSN (online) 2090-665X
    ISSN 2090-6641
    DOI 10.1155/2021/1979332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Neisseria cinerea-Mediated Peritonitis in an End-Stage Renal Disease Patient on Continuous Ambulatory Peritoneal Dialysis.

    Garcha, Amarinder / Roy, Sasmit / Ayala, Raul / Balla, Mamtha / Adapa, Sreedhar

    Cureus

    2021  Volume 13, Issue 12, Page(s) e20661

    Abstract: Peritonitis can be a lethal outcome of peritoneal dialysis (PD), often leading to significant morbidity and mortality. It is caused mostly by gram-positive organisms. Neisseria cinerea is a gram-negative nasal and oropharyngeal commensal, rarely reported ...

    Abstract Peritonitis can be a lethal outcome of peritoneal dialysis (PD), often leading to significant morbidity and mortality. It is caused mostly by gram-positive organisms. Neisseria cinerea is a gram-negative nasal and oropharyngeal commensal, rarely reported as an etiology of peritonitis in PD patients. Our patient was a 37-year-old female on continuous ambulatory peritoneal dialysis for the last seven years, who developed peritonitis found to be from Neisseria cinerea. She didn't respond to broad-spectrum antibiotics well and had to be switched to intermittent hemodialysis. We highlight this important microorganism that can lead to significant morbidity and an unfortunate change in dialysis modality.
    Language English
    Publishing date 2021-12-24
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.20661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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