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  1. Article ; Online: Rotator Cuff Repair in Pediatric and Adolescent Athletes: Indications and Outcomes.

    Caldaria, Antonio / Giovannetti de Sanctis, Edoardo / Palumbo, Alessio / Franceschi, Francesco / Maffulli, Nicola

    Sports medicine and arthroscopy review

    2023  Volume 31, Issue 3, Page(s) 62–66

    Abstract: Rotator cuff (RC) tears in pediatric and adolescent athletes are rare events. In these patients, RC tears are more likely to be traumatic or related to overuse among overhead. Repeated movements of abduction and external rotation are frequent mechanisms ... ...

    Abstract Rotator cuff (RC) tears in pediatric and adolescent athletes are rare events. In these patients, RC tears are more likely to be traumatic or related to overuse among overhead. Repeated movements of abduction and external rotation are frequent mechanisms of injury. The supraspinatus is the most commonly involved tendon and the articular-sided tears are more common than the bursal side. Magnetic resonance imaging is considered the gold standard for diagnosing RC tears. Conservative treatment, arthroscopic, and open repair are all effective treatment methods depending on the type of injury. The risk of growth plate injury in these patients should be always considered when planning surgical interventions. Return to sport for competitive-level throwing athletes represents the greatest challenge in the treatment of these injuries.
    MeSH term(s) Humans ; Adolescent ; Child ; Rotator Cuff/surgery ; Rotator Cuff Injuries/surgery ; Tendon Injuries/surgery ; Tendons ; Treatment Outcome ; Athletes ; Magnetic Resonance Imaging ; Arthroscopy/methods
    Language English
    Publishing date 2023-11-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1174179-x
    ISSN 1538-1951 ; 1062-8592
    ISSN (online) 1538-1951
    ISSN 1062-8592
    DOI 10.1097/JSA.0000000000000373
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    Zs.A 3879: Show issues Location:
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  2. Article ; Online: New tip-apex distance and calcar-referenced tip-apex distance cut-offs may be the best predictors for cut-out risk after intramedullary fixation of proximal femur fractures.

    Caruso, Gaetano / Corradi, Nicola / Caldaria, Antonio / Bottin, Daniele / Lo Re, Dario / Lorusso, Vincenzo / Morotti, Chiara / Valpiani, Giorgia / Massari, Leo

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 357

    Abstract: Cut-out is one of the most common mechanical failures in the internal fixation of trochanteric hip fractures. The tip-apex distance (TAD), and the calcar-referenced tip apex distance (CalTAD) are the radiographic parameters that most predict the risk of ... ...

    Abstract Cut-out is one of the most common mechanical failures in the internal fixation of trochanteric hip fractures. The tip-apex distance (TAD), and the calcar-referenced tip apex distance (CalTAD) are the radiographic parameters that most predict the risk of cut-out. The optimal CalTAD value has not yet been defined, but the optimal TAD value is reported as 25 mm or less. However, this cut-off is highly specific but poorly sensitive. The aim of this study was to determine highly specific and sensitive TAD and CalTAD values and shed light on the role of other clinical variables. A total of 604 patients were included in this retrospective cross-sectional study. For each patient the following data were recorded: number of cut-out, AO/OTA classification, quality of the reduction, type of nail, cervicodiaphyseal angle, type of distal locking, post-operative weight-bearing, TAD and CalTAD values, and the position of the screw head in the femoral head according to the Cleveland system. The incidence of cut-out across the sample was 3.1%. The median TAD in the cut-out group was 38.72, while in the no cut-out group it was 22.16. The median CalTAD in the cut-out group was 39.34, while in the no cut-out group it was 22.19. The cut-off values for TAD and CalTAD with highest value of sensitivity and specificity for the risk of cut-out were 34.8 and 35.2, respectively. The incidence of cut-out can be reduced by performing careful minimal reduction and ensuring stable fixation by avoiding TAD > 34.8 mm and CalTAD > 35.2 mm.
    MeSH term(s) Aged ; Aged, 80 and over ; Anatomic Landmarks ; Bone Nails ; Bone Screws ; Cross-Sectional Studies ; Databases, Factual ; Female ; Femur/diagnostic imaging ; Femur/injuries ; Femur/surgery ; Fracture Fixation, Intramedullary/adverse effects ; Fracture Fixation, Intramedullary/instrumentation ; Hip Fractures/diagnostic imaging ; Hip Fractures/surgery ; Humans ; Male ; Predictive Value of Tests ; Prosthesis Failure ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Treatment Failure
    Language English
    Publishing date 2022-01-10
    Publishing country England
    Document type Comparative Study ; Journal Article ; Observational Study
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-04252-1
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  3. Article ; Online: New tip-apex distance and calcar-referenced tip-apex distance cut-offs may be the best predictors for cut-out risk after intramedullary fixation of proximal femur fractures

    Gaetano Caruso / Nicola Corradi / Antonio Caldaria / Daniele Bottin / Dario Lo Re / Vincenzo Lorusso / Chiara Morotti / Giorgia Valpiani / Leo Massari

    Scientific Reports, Vol 12, Iss 1, Pp 1-

    2022  Volume 10

    Abstract: Abstract Cut-out is one of the most common mechanical failures in the internal fixation of trochanteric hip fractures. The tip-apex distance (TAD), and the calcar-referenced tip apex distance (CalTAD) are the radiographic parameters that most predict the ...

    Abstract Abstract Cut-out is one of the most common mechanical failures in the internal fixation of trochanteric hip fractures. The tip-apex distance (TAD), and the calcar-referenced tip apex distance (CalTAD) are the radiographic parameters that most predict the risk of cut-out. The optimal CalTAD value has not yet been defined, but the optimal TAD value is reported as 25 mm or less. However, this cut-off is highly specific but poorly sensitive. The aim of this study was to determine highly specific and sensitive TAD and CalTAD values and shed light on the role of other clinical variables. A total of 604 patients were included in this retrospective cross-sectional study. For each patient the following data were recorded: number of cut-out, AO/OTA classification, quality of the reduction, type of nail, cervicodiaphyseal angle, type of distal locking, post-operative weight-bearing, TAD and CalTAD values, and the position of the screw head in the femoral head according to the Cleveland system. The incidence of cut-out across the sample was 3.1%. The median TAD in the cut-out group was 38.72, while in the no cut-out group it was 22.16. The median CalTAD in the cut-out group was 39.34, while in the no cut-out group it was 22.19. The cut-off values for TAD and CalTAD with highest value of sensitivity and specificity for the risk of cut-out were 34.8 and 35.2, respectively. The incidence of cut-out can be reduced by performing careful minimal reduction and ensuring stable fixation by avoiding TAD > 34.8 mm and CalTAD > 35.2 mm.
    Keywords Medicine ; R ; Science ; Q
    Subject code 000
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Should evoked potential monitoring be used in degenerative cervical spine surgery? A systematic review.

    Di Martino, Alberto / Papalia, Rocco / Caldaria, Antonio / Torre, Guglielmo / Denaro, Luca / Denaro, Vincenzo

    Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology

    2019  Volume 20, Issue 1, Page(s) 19

    Abstract: Background: Intraoperative somatosensory evoked potential (SSEP) and transcranial motor evoked potential (tcMEP) monitoring are frequently used in spinal as well as spinal cord surgery for so-called intraoperative neuromonitoring (IONM), while the ... ...

    Abstract Background: Intraoperative somatosensory evoked potential (SSEP) and transcranial motor evoked potential (tcMEP) monitoring are frequently used in spinal as well as spinal cord surgery for so-called intraoperative neuromonitoring (IONM), while the combination of these techniques is known as concomitant multimodal intraoperative monitoring (MIOM). The aim of this review is to collect available evidence concerning use of IONM and MIOM in cervical decompression surgery in the degenerative setting and attempt to identify the best practice to be advocated.
    Materials and methods: A review of the PubMed and MEDLINE databases and Cochrane Central Registry of Controlled Trials was performed. Studies were included if they involved patients who underwent cervical spine decompression surgery for degenerative stenosis with use of IONM or MIOM and where sensitivity/specificity was reported.
    Results: In the identified studies, the sensitivity of SSEP was estimated to be between 22 and 100% with constant specificity of 100%. In the included studies, the sensitivity of MEP was estimated to be between 78 and 100% with specificity ranging from 83.2 to 100%.
    Conclusions: On the basis of available evidence, MIOM could be a helpful tool in decompression cervical spine surgery in patients affected by degenerative spinal stenosis, since it is associated with high specificity and sensitivity for detection of intraoperative neural damage. However, evidence is still lacking regarding patient selection to identify individuals in whom monitoring is indicated.
    Level of evidence: IV (systematic review of studies with LOE II to IV).
    MeSH term(s) Evoked Potentials, Somatosensory/physiology ; Humans ; Intraoperative Neurophysiological Monitoring/methods ; Middle Aged ; Neurosurgical Procedures/methods ; Retrospective Studies ; Spinal Stenosis/physiopathology ; Spinal Stenosis/surgery
    Language English
    Publishing date 2019-04-02
    Publishing country Italy
    Document type Journal Article ; Systematic Review
    ZDB-ID 2043336-0
    ISSN 1590-9999 ; 1590-9921
    ISSN (online) 1590-9999
    ISSN 1590-9921
    DOI 10.1186/s10195-019-0524-4
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    Zs.A 6153: Show issues Location:
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  5. Article ; Online: COVID-19 and SARS: Differences and similarities.

    Caldaria, Antonio / Conforti, Claudio / Di Meo, Nicola / Dianzani, Caterina / Jafferany, Mohammad / Lotti, Torello / Zalaudek, Iris / Giuffrida, Roberta

    Dermatologic therapy

    2020  Volume 33, Issue 4, Page(s) e13395

    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; SARS Virus/isolation & purification ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome/epidemiology ; Severe Acute Respiratory Syndrome/virology
    Keywords covid19
    Language English
    Publishing date 2020-04-30
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13395
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    Zs.A 5181: Show issues Location:
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  6. Article ; Online: Metastatic epidural spinal cord compression.

    Di Martino, Alberto / Caldaria, Antonio / De Vivo, Vincenzo / Denaro, Vincenzo

    Expert review of anticancer therapy

    2016  Volume 16, Issue 11, Page(s) 1189–1198

    Abstract: Introduction: Metastatic epidural spinal cord compression (MESSC) is a frequent event in patients affected by solid tumor metastases. Current available approaches for MESCC include corticosteroids, radiotherapy and surgery. In the last few years, ... ...

    Abstract Introduction: Metastatic epidural spinal cord compression (MESSC) is a frequent event in patients affected by solid tumor metastases. Current available approaches for MESCC include corticosteroids, radiotherapy and surgery. In the last few years, surgery has evolved from decompression by laminectomy alone, with the introduction of instrumentation systems by metalware (screws and hooks), and this has been associated to an improvement of clinical results compared to radiotherapy alone. Areas covered: In this narrative review, we outline the phases of management of cancer patients affected by MESSC, and discuss the timing of treatments, their impact on the Quality of life (QoL), and the relative benefits and harms of surgery and radiotherapy. Expert commentary: Despite the fact that clinical and surgical trials will be required to determine the most appropriate surgical technique and timing of surgery, we do expect a newer and more important role for radiotherapy in the management of MESCC patients in the next future. In particular, the implementation of radiotactic stereosurgery as adjuvant to decompressive surgery is expected to increase in the next few years, above all in those patients that can be candidate to the so called separation surgery.
    Language English
    Publishing date 2016-10-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2112544-2
    ISSN 1744-8328 ; 1473-7140
    ISSN (online) 1744-8328
    ISSN 1473-7140
    DOI 10.1080/14737140.2016.1240038
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  7. Article: COVID-19 and SARS: Differences and similarities

    Caldaria, Antonio / Conforti, Claudio / Di Meo, Nicola / Dianzani, Caterina / Jafferany, Mohammad / Lotti, Torello / Zalaudek, Iris / Giuffrida, Roberta

    Dermatol Ther

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #47928
    Database COVID19

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  8. Article ; Online: Adalimumab-associated spondylodiscitis: A new or underestimated side effect?

    Conforti, Claudio / Caldaria, Antonio / Dri, Arianna / Toffoli, Ludovica / Zelin, Enrico / Vezzoni, Roberta / Nan, Katiuscia / Degrassi, Ferruccio / Giuffrida, Roberta / Zalaudek, Iris / di Meo, Nicola

    Dermatologic therapy

    2020  Volume 33, Issue 4, Page(s) e13468

    MeSH term(s) Adalimumab/adverse effects ; Discitis/diagnosis ; Discitis/drug therapy ; Humans ; Iatrogenic Disease
    Chemical Substances Adalimumab (FYS6T7F842)
    Language English
    Publishing date 2020-06-01
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13468
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  9. Article ; Online: COVID ‐19 and SARS

    Caldaria, Antonio / Conforti, Claudio / Di Meo, Nicola / Dianzani, Caterina / Jafferany, Mohammad / Lotti, Torello / Zalaudek, Iris / Giuffrida, Roberta

    Dermatologic Therapy

    Differences and similarities

    2020  Volume 33, Issue 4

    Keywords Dermatology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13395
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  10. Article ; Online: Diagnosis and treatment of melanoma bone metastasis: A multidisciplinary approach.

    Caldaria, Antonio / Giuffrida, Roberta / di Meo, Nicola / Massari, Leo / Dianzani, Caterina / Cannavò, Serafinella Patrizia / Degrassi, Ferruccio / Casablanca, Edoardo / Zalaudek, Iris / Conforti, Claudio

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14193

    Abstract: Bone is the fourth most common site of melanoma metastasis after lung, liver, and brain. Melanoma bone metastases typically occur in patients who already have widespread metastases in other organs. Current available approaches for bone metastases from ... ...

    Abstract Bone is the fourth most common site of melanoma metastasis after lung, liver, and brain. Melanoma bone metastases typically occur in patients who already have widespread metastases in other organs. Current available approaches for bone metastases from melanoma include chemotherapy, radiotherapy, biological therapy, combination therapy, and surgery. In this narrative review, we describe the management of patients affected by melanoma bone metastases, discussing the diagnostic and treatment approaches as well as their impact on survival and quality of life. Despite the fact that clinical and surgical trials will be required to determine the most appropriate treatment, we do expect a newer and more important role of multidisciplinary approach in the management of melanoma patients with bone metastases in the next future.
    MeSH term(s) Brain Neoplasms ; Combined Modality Therapy ; Humans ; Melanoma/therapy ; Quality of Life
    Language English
    Publishing date 2020-09-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14193
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