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  1. Article ; Online: Rising rates of paracoccidioidomycosis-related hospitalizations and in-hospital deaths, Rio de Janeiro, Brazil (2010-2019).

    Falcão, Eduardo Mastrangelo Marinho / de Macedo, Priscila Marques / Coutinho, Ziadir Francisco / Bastos, Francisco Inacio / do Valle, Antonio Carlos Francesconi

    Medical mycology

    2024  Volume 62, Issue 5

    Abstract: ... hospitalizations registered in Rio de Janeiro. We highlight the rising rates, reflecting the increase in the number of acute ...

    Abstract The epidemiological dynamics of paracoccidioidomycosis (PCM) has been changing over the years. We analyzed secondary public data from the Hospital Information System of the Brazilian Unified Health System (SIH/SUS), focusing on PCM-related hospitalizations and in-hospital deaths. In the period between 2010 and 2019, 396 hospitalizations and 30 deaths were related to PCM among 7 073 334 hospitalizations registered in Rio de Janeiro. We highlight the rising rates, reflecting the increase in the number of acute forms previously reported. Urgent public health policies are essential to prevent poor outcomes related to this neglected mycosis.
    MeSH term(s) Brazil/epidemiology ; Humans ; Paracoccidioidomycosis/epidemiology ; Paracoccidioidomycosis/mortality ; Hospitalization/statistics & numerical data ; Hospital Mortality ; Male ; Middle Aged ; Female ; Adult ; Aged ; Adolescent ; Young Adult ; Child ; Child, Preschool ; Aged, 80 and over
    Language English
    Publishing date 2024-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1421796-x
    ISSN 1460-2709 ; 1369-3786
    ISSN (online) 1460-2709
    ISSN 1369-3786
    DOI 10.1093/mmy/myae048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 in patients with paracoccidioidomycosis.

    de Macedo, Priscila Marques / Benko, Lorena Macedo Pestana / Falcão, Eduardo Mastrangelo Marinho / Nosanchuk, Joshua D / Almeida-Paes, Rodrigo / do Valle, Antonio Carlos Francesconi

    PLoS neglected tropical diseases

    2023  Volume 17, Issue 5, Page(s) e0011322

    Abstract: ... for infectious diseases at Rio de Janeiro, Brazil.: Methods: We reviewed the medical records from patients diagnosed ...

    Abstract Introduction: In 2020, we reported the first patient with concomitant COVID-19 and paracoccidioidomycosis (PCM). Since then, no other cases have been recorded in the literature. We aim to update information on the occurrence of COVID-19 in patients with PCM followed at a reference center for infectious diseases at Rio de Janeiro, Brazil.
    Methods: We reviewed the medical records from patients diagnosed with PCM who presented with clinical symptoms, radiological findings, and/or laboratory diagnosis of COVID-19 at any time during their acute or follow-up care. The clinical profiles of these patients were described.
    Results: Between March 2020 and September 2022, we identified six individuals with COVID-19 among the 117 patients with PCM evaluated. The median age was 38 years and the male to female ratio 2:1. Most patients (n = 5) presented for evaluation due to acute PCM. The severity of COVID-19 ranged from mild to severe in acute PCM and only the single patient with chronic PCM died.
    Conclusions: There is a range of disease severity in COVID-19 and PCM co-infection and concomitant disease may represent a severe association, especially in the chronic type of the mycosis with pulmonary involvement. As COVID-19 and chronic PCM share similar clinical aspects and PCM is neglected, it is probable that COVID-19 has been hampering simultaneous PCM diagnosis, which can explain the absence of new co-infection reports. With the continued persistence of COVID-19 globally, these findings further suggest that more attention by providers is necessary to identify co-infections with Paracoccidioides.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Paracoccidioidomycosis/complications ; Paracoccidioidomycosis/diagnosis ; Paracoccidioidomycosis/epidemiology ; Coinfection/complications ; Brazil/epidemiology ; COVID-19/complications ; COVID-19/diagnosis ; Paracoccidioides
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0011322
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The present and future research agenda of sporotrichosis on the silver anniversary of zoonotic sporotrichosis in Rio de Janeiro, Brazil.

    Almeida-Paes, Rodrigo / do Valle, Antonio Carlos Francesconi / Freitas, Dayvison Francis Saraiva / de Macedo, Priscila Marques / Zancopé-Oliveira, Rosely Maria / Gutierrez-Galhardo, Maria Clara

    Memorias do Instituto Oswaldo Cruz

    2024  Volume 119, Page(s) e230208

    Abstract: ... in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying the emergence ...

    Abstract Twenty-five years have passed since the initial observation of endemic zoonotic sporotrichosis in Rio de Janeiro, Brazil. Since then, this disease has spread throughout South America. Accompanying the emergence of this mycosis, some progress has been made, including the expansion of a research network in this field and higher visibility of sporotrichosis within government authorities and funding agencies. However, there are still some challenges to curbing the expansion of this disease in the coming years. These include the development of rapid and accurate diagnostic tests, new antifungal drugs, particularly for the treatment of extracutaneous manifestations of sporotrichosis, and more comprehensive care for cats with sporotrichosis. Including these actions in the sporotrichosis research agenda is required so as to change the development of this disease in the years to come.
    MeSH term(s) Animals ; Cats ; Sporotrichosis/veterinary ; Sporotrichosis/epidemiology ; Zoonoses ; Brazil/epidemiology ; Anniversaries and Special Events ; Antifungal Agents ; Sporothrix ; Cat Diseases
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2024-02-12
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 953293-6
    ISSN 1678-8060 ; 0074-0276
    ISSN (online) 1678-8060
    ISSN 0074-0276
    DOI 10.1590/0074-02760230208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Performance of Two Commercial Assays for the Detection of Serum

    Almeida-Paes, Rodrigo / Almeida, Marcos de Abreu / de Macedo, Priscila Marques / Caceres, Diego H / Zancopé-Oliveira, Rosely Maria

    Journal of fungi (Basel, Switzerland)

    2022  Volume 8, Issue 7

    Abstract: Besides the relevance of aspergillosis in neutropenic patients, this mycosis has gained significance among non-neutropenic patients in last years. The detection ... ...

    Abstract Besides the relevance of aspergillosis in neutropenic patients, this mycosis has gained significance among non-neutropenic patients in last years. The detection of
    Language English
    Publishing date 2022-07-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8070741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Protease inhibitors from

    Guimarães Santana, Brenda Conceição / de Almeida Marques, Daisymara Priscila / Dos Santos Freitas, Andria / Ferreira, Monaliza Macêdo / de Sousa Lopes, Danielle / Bagno, Flávia Fonseca / Guimarães da Fonseca, Flávio / Dos Reis, Jordana Grazziela Alves Coelho / Oliveira Mendes, Tiago Antônio de / Santos, Jane Lima Dos / Pirovani, Carlos Priminho

    Heliyon

    2023  Volume 9, Issue 5, Page(s) e15860

    Abstract: SARS-CoV-2 is a newly emerging virus from ... ...

    Abstract SARS-CoV-2 is a newly emerging virus from the
    Language English
    Publishing date 2023-05-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e15860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Osteoarticular Sporotrichosis of the Knee Caused by

    de Sousa, Bruno Ivanovinsky Costa / Ferreira, Livia Cristina Fonseca / de Lima, Marcella Morgado Ramiro / Netto, Juliana Dos Santos Barbosa / Astacio, Guis Saint-Martin / Bernardes-Engemann, Andréa Reis / de Macedo, Priscila Marques / Gutierrez-Galhardo, Maria Clara / Freitas, Dayvison Francis Saraiva

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 10

    Abstract: Sporotrichosis is the most frequent subcutaneous or implantation mycosis in Latin America, and its transmission occurs as a result of traumatic inoculation into the skin by organic matter containing the thermodimorphic fungi of the ... ...

    Abstract Sporotrichosis is the most frequent subcutaneous or implantation mycosis in Latin America, and its transmission occurs as a result of traumatic inoculation into the skin by organic matter containing the thermodimorphic fungi of the genus
    Language English
    Publishing date 2023-09-23
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9100956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide.

    Lyra, Marcelo Rosandiski / Sokoloski, Vanessa / de Macedo, Priscila Marques / Azevedo, Anna Carolina Procópio de

    Anais brasileiros de dermatologia

    2021  Volume 96, Issue 2, Page(s) 231–233

    Abstract: Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. ... ...

    Abstract Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. The patient was cured after the introduction of saturated potassium iodide solution. Sporothrix brasiliensis was the identified species, presenting a susceptibility profile to itraconazole and terbinafine. This fact suggests that therapeutic failure is probably related to the host-fungus interaction rather than drug resistance. It is possible that the immunomodulatory action of the saturated potassium iodide solution may have played an important role in curing this patient.
    MeSH term(s) Antifungal Agents/therapeutic use ; Humans ; Itraconazole ; Potassium Iodide/therapeutic use ; Sporothrix ; Sporotrichosis/drug therapy
    Chemical Substances Antifungal Agents ; Potassium Iodide (1C4QK22F9J) ; Itraconazole (304NUG5GF4)
    Language English
    Publishing date 2021-01-31
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1016/j.abd.2020.04.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Beyond Domestic Cats: Environmental Detection of

    Almeida-Silva, Fernando / Rabello, Vanessa Brito de Souza / Scramignon-Costa, Bruno de Souza / Zancopé-Oliveira, Rosely Maria / de Macedo, Priscila Marques / Almeida-Paes, Rodrigo

    Journal of fungi (Basel, Switzerland)

    2022  Volume 8, Issue 6

    Abstract: In Brazil, sporotrichosis has transitioned from a rural to urban disease, driven by a shift in the initiation of infection from the accidental inoculation of organic matter to the traumatic implantation of the fungus by cats. Since the emergence of ... ...

    Abstract In Brazil, sporotrichosis has transitioned from a rural to urban disease, driven by a shift in the initiation of infection from the accidental inoculation of organic matter to the traumatic implantation of the fungus by cats. Since the emergence of zoonotic sporotrichosis caused by
    Language English
    Publishing date 2022-06-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8060604
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Proceedings of the Second International Meeting on Endemic Mycoses of the Americas (IMEMA), and First International Symposium on Implantation Mycoses (ISIM).

    Fernandez, Norma B / Cáceres, Diego H / Serrano, Julian A / Bonifaz, Alexandro / Canteros, Cristina E / Suarez-Alvarez, Roberto / Oliveira, Rosely Maria Zancope / Cognialli, Regielly C R / de Macedo, Priscila Marques / Gomez, Beatriz L / Tobon, Angela M / Taborda, Carlos / Chiller, Tom / Brunelli, Jose Guillermo Pereira / Smith, Dallas J / de Melo Teixeira, Marcus / Queiroz-Telles, Flavio / Effron, Guillermo Garcia / Ardizzoli, Karina /
    Negroni, Ricardo / Giusiano, Gustavo

    Medical mycology

    2024  

    Abstract: The Second International Meeting on Endemic Mycoses of the Americas (IMEMA) and the First International Symposium on Implantation Mycoses (ISIM) took place in Santiago del Estero, Argentina during September 25-27th, 2023. The conference provided a ... ...

    Abstract The Second International Meeting on Endemic Mycoses of the Americas (IMEMA) and the First International Symposium on Implantation Mycoses (ISIM) took place in Santiago del Estero, Argentina during September 25-27th, 2023. The conference provided a platform for researchers, clinicians, and experts to discuss the latest developments in the field of endemic and implantation mycoses. Topics included epidemiology, diagnostic advances, treatment strategies, and the impact of environmental factors in the spread of these fungal diseases. IMEMA and ISIM contributed to the regional discourse on the mycoses, emphasizing the importance of international cooperation in addressing these public health challenges.
    Language English
    Publishing date 2024-05-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1421796-x
    ISSN 1460-2709 ; 1369-3786
    ISSN (online) 1460-2709
    ISSN 1369-3786
    DOI 10.1093/mmy/myae054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The State of the Art in Transcriptomics and Proteomics of Clinically Relevant

    Procópio-Azevedo, Anna Carolina / de Abreu Almeida, Marcos / Almeida-Paes, Rodrigo / Zancopé-Oliveira, Rosely Maria / Gutierrez-Galhardo, Maria Clara / de Macedo, Priscila Marques / Novaes, Evandro / Bailão, Alexandre Melo / de Almeida Soares, Célia Maria / Freitas, Dayvison Francis Saraiva

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 8

    Abstract: Proteomics provide a robust approach to profile and quantify proteins within cells, organs, or tissues, providing comprehensive insights about the dynamics of cellular processes, modifications, and interactions. Similarly, understanding the transcriptome ...

    Abstract Proteomics provide a robust approach to profile and quantify proteins within cells, organs, or tissues, providing comprehensive insights about the dynamics of cellular processes, modifications, and interactions. Similarly, understanding the transcriptome is essential to decipher functional elements of the genome, unraveling the mechanisms of disease development and the molecular constituents of cells and tissues. Some thermodimorphic fungi of the genus
    Language English
    Publishing date 2023-07-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9080790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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