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  1. Article ; Online: Status dissociatus and movement disorders in anti N-methyl-d-aspartate receptor (anti NMDAR) encephalitis; diagnostic challenges ahead.

    Badrfam, Rahim / Zandifar, Atefeh

    General hospital psychiatry

    2024  Volume 88, Page(s) 75–76

    MeSH term(s) Humans ; Encephalitis ; Movement Disorders/diagnosis ; Movement Disorders/etiology ; Receptors, Amino Acid ; Anti-N-Methyl-D-Aspartate Receptor Encephalitis/diagnosis ; Receptors, N-Methyl-D-Aspartate
    Chemical Substances aspartic acid receptor ; Receptors, Amino Acid ; Receptors, N-Methyl-D-Aspartate
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Letter
    ZDB-ID 392299-6
    ISSN 1873-7714 ; 0163-8343
    ISSN (online) 1873-7714
    ISSN 0163-8343
    DOI 10.1016/j.genhosppsych.2024.01.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Efficacy of empagliflozin as adjunctive therapy to citalopram in major depressive disorder: a randomized double-blind, placebo-controlled clinical trial.

    Zandifar, Atefeh / Panahi, Maryam / Badrfam, Rahim / Qorbani, Mostafa

    BMC psychiatry

    2024  Volume 24, Issue 1, Page(s) 163

    Abstract: Background: Major depressive disorder is one of the most common psychiatric disorders, which is associated with a high disease burden. Current treatments using antidepressants have limitations, so using medication with neuromodulating and anti- ... ...

    Abstract Background: Major depressive disorder is one of the most common psychiatric disorders, which is associated with a high disease burden. Current treatments using antidepressants have limitations, so using medication with neuromodulating and anti-inflammatory properties alongside them could be helpful. In a clinical trial, we studied the effectiveness of empagliflozin, a blood sugar-lowering drug, as an adjunctive therapy to reduce the severity of depression symptoms.
    Methods: A number of outpatients with moderate to severe depression (Hamilton Depression Rating Scale (HDRS) > = 17) who were not under related medication or had not taken medication for at least the last two months, had an age range of 18-60 years and had written informed consent to enter the study (N = 90) were randomly divided into two groups receiving placebo or empagliflozin (10 mg daily) combined with citalopram (40 mg daily) based on permuted block randomization method in an 8-week randomized, double-blind, placebo-controlled clinical trial. They were evaluated using the HDRS in weeks 0, 4, and 8.
    Results: HDRS scores were equal to 28.42(± 3.83), 20.20(± 3.82), and 13.42(± 3.42) in the placebo group during weeks 0,4, and 8, respectively. These scores were 27.36(± 3.77), 13.76(± 1.40), and 7.00(± 1.13), respectively, for the group treated with empagliflozin. Compared to the control group, patients treated with empagliflozin using repeated-measures ANOVA showed greater improvement in reducing the severity of depression symptoms over time (p value = 0.0001).
    Conclusions: Considering the promising findings in this clinical trial, further study of empagliflozin as adjunctive therapy in MDD with larger sample sizes and longer follow-ups is recommended.
    MeSH term(s) Humans ; Antidepressive Agents/therapeutic use ; Benzhydryl Compounds ; Citalopram/therapeutic use ; Depressive Disorder, Major/drug therapy ; Double-Blind Method ; Drug Therapy, Combination ; Glucosides ; Treatment Outcome ; Adolescent ; Young Adult ; Adult ; Middle Aged
    Chemical Substances Antidepressive Agents ; Benzhydryl Compounds ; Citalopram (0DHU5B8D6V) ; empagliflozin (HDC1R2M35U) ; Glucosides
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2050438-X
    ISSN 1471-244X ; 1471-244X
    ISSN (online) 1471-244X
    ISSN 1471-244X
    DOI 10.1186/s12888-024-05627-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Efficacy of spironolactone as adjunctive therapy to sodium valproate in bipolar-I disorder: A double-blind, randomized, placebo-controlled clinical trial.

    Zandifar, Atefeh / Badrfam, Rahim / Gholamian, Fatemeh / Shafiee, Arman

    Brain and behavior

    2023  Volume 13, Issue 12, Page(s) e3313

    Abstract: Introduction: Treatment of mood and cognitive symptoms of patients with bipolar disorder is associated with many complications and is generally not associated with therapeutic satisfaction. In this clinical trial, we evaluated the effectiveness of ... ...

    Abstract Introduction: Treatment of mood and cognitive symptoms of patients with bipolar disorder is associated with many complications and is generally not associated with therapeutic satisfaction. In this clinical trial, we evaluated the effectiveness of spironolactone in controlling mood and cognitive symptoms, sleep quality, appetite, and body mass index in patients with bipolar disorder in manic episodes.
    Methods: Sixty inpatients with bipolar disorder in manic episodes were treated with spironolactone/placebo in an 8-week randomized, double-blind, placebo-controlled clinical trial. They were evaluated using the Young Mania Rating Scale (YMRS), mini-mental state examination (MMSE), Pittsburgh sleep quality index, Simplified Nutritional Appetite Questionnaire, and body mass index in weeks 1, 4, and 8.
    Results: For cognitive impairment (MMSE), there were significant interaction effects of group and time at week 8 (B = -1.60, SE = 0.69, t = -2.33, p = .021) such that individuals in the spironolactone group experienced more improvement in their cognitive performance. For manic symptoms (YMRS), there were no significant interaction effects of group and time at week 8 (B = -2.53, SE = 1.46, t = -1.73, p = .085).
    Conclusions: Considering the promising findings in this clinical trial, further study of spironolactone as adjunctive therapy in bipolar disorder in manic episodes with larger sample sizes, multicenter settings, and longer follow-ups are recommended.
    MeSH term(s) Humans ; Bipolar Disorder/diagnosis ; Double-Blind Method ; Drug Therapy, Combination ; Mania/drug therapy ; Psychiatric Status Rating Scales ; Spironolactone/therapeutic use ; Treatment Outcome ; Valproic Acid/therapeutic use
    Chemical Substances Spironolactone (27O7W4T232) ; Valproic Acid (614OI1Z5WI)
    Language English
    Publishing date 2023-11-06
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2623587-0
    ISSN 2162-3279 ; 2162-3279
    ISSN (online) 2162-3279
    ISSN 2162-3279
    DOI 10.1002/brb3.3313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Asian journal of psychiatry and COVID-19; A window with a transcultural view - Reply to editor's letter.

    Badrfam, Rahim / Zandifar, Atefeh

    Asian journal of psychiatry

    2021  Volume 58, Page(s) 102604

    MeSH term(s) Asia/epidemiology ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/psychology ; Communicable Disease Control/methods ; Communicable Disease Control/organization & administration ; Ethnopsychology/trends ; Humans ; Iran ; Mental Health/trends ; Periodicals as Topic/trends ; Publishing/organization & administration ; SARS-CoV-2
    Language English
    Publishing date 2021-02-16
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2021.102604
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Child abuse in low- and middle-income countries during the COVID-19 pandemic; the need for culture-based interventions.

    Badrfam, Rahim / Zandifar, Atefeh

    Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc

    2021  Volume 34, Issue 4, Page(s) 360

    MeSH term(s) COVID-19 ; Child ; Child Abuse ; Developing Countries ; Humans ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-05-25
    Publishing country England
    Document type Letter
    ZDB-ID 1018093-x
    ISSN 1744-6171 ; 1073-6077 ; 0897-9685
    ISSN (online) 1744-6171
    ISSN 1073-6077 ; 0897-9685
    DOI 10.1111/jcap.12330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Mass immunization and COVID-19: the need for continued primary health care.

    Badrfam, Rahim / Zandifar, Atefeh

    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit

    2021  Volume 27, Issue 3, Page(s) 312–313

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Humans ; Mass Vaccination ; Mediterranean Region/epidemiology ; Primary Health Care ; SARS-CoV-2
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-03-23
    Publishing country Egypt
    Document type Letter
    ZDB-ID 1291071-5
    ISSN 1687-1634 ; 1020-3397
    ISSN (online) 1687-1634
    ISSN 1020-3397
    DOI 10.26719/2021.27.3.312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19: Considering the prevalence of schizophrenia in the coming decades.

    Zandifar, Atefeh / Badrfam, Rahim

    Psychiatry research

    2020  Volume 288, Page(s) 112982

    Keywords covid19
    Language English
    Publishing date 2020-04-05
    Publishing country Ireland
    Document type Letter
    ZDB-ID 445361-x
    ISSN 1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
    ISSN (online) 1872-7123 ; 1872-7506
    ISSN 0925-4927 ; 0165-1781
    DOI 10.1016/j.psychres.2020.112982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: COVID-19 and Melancholia: Different Perception of the Concept of Stigma and Loss.

    Badrfam, Rahim / Zandifar, Atefeh

    Iranian journal of psychiatry

    2020  Volume 15, Issue 3, Page(s) 264–265

    Keywords covid19
    Language English
    Publishing date 2020-10-28
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2388800-3
    ISSN 2008-2215 ; 1735-4587
    ISSN (online) 2008-2215
    ISSN 1735-4587
    DOI 10.18502/ijps.v15i3.3824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Stigma Over COVID-19; New Conception Beyond Individual Sense.

    Badrfam, Rahim / Zandifar, Atefeh

    Archives of medical research

    2020  Volume 51, Issue 6, Page(s) 593–594

    Keywords covid19
    Language English
    Publishing date 2020-05-20
    Publishing country United States
    Document type Letter
    ZDB-ID 1156844-6
    ISSN 1873-5487 ; 0188-4409 ; 0188-0128
    ISSN (online) 1873-5487
    ISSN 0188-4409 ; 0188-0128
    DOI 10.1016/j.arcmed.2020.05.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: COVID-19 and mental health: An Iranian perspective.

    Badrfam, Rahim / Zandifar, Atefeh

    Asian journal of psychiatry

    2020  Volume 54, Page(s) 102266

    MeSH term(s) COVID-19 ; Humans ; Iran ; Mental Health ; Social Capital
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2020.102266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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