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  1. Article ; Online: From FDA to MHRA: are drug regulators for hire?

    Demasi, Maryanne

    BMJ (Clinical research ed.)

    2022  Volume 377, Page(s) o1538

    MeSH term(s) Humans ; Personnel Selection
    Language English
    Publishing date 2022-06-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.o1538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.10: Show issues Location:
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  2. Article ; Online: Covid-19: Is the US compensation scheme for vaccine injuries fit for purpose?

    Demasi, Maryanne

    BMJ (Clinical research ed.)

    2022  Volume 377, Page(s) o919

    MeSH term(s) COVID-19/prevention & control ; Compensation and Redress ; Humans ; Vaccines
    Chemical Substances Vaccines
    Language English
    Publishing date 2022-04-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.o919
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: FDA oversight of clinical trials is "grossly inadequate," say experts.

    Demasi, Maryanne

    BMJ (Clinical research ed.)

    2022  Volume 379, Page(s) o2628

    MeSH term(s) Humans ; United States ; United States Food and Drug Administration ; Clinical Trials as Topic
    Language English
    Publishing date 2022-11-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.o2628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.10: Show issues Location:
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  4. Article ; Online: FDA urged to publish follow-up studies on covid-19 vaccine safety signals.

    Demasi, Maryanne

    BMJ (Clinical research ed.)

    2022  Volume 379, Page(s) o2527

    MeSH term(s) Humans ; COVID-19 Vaccines/adverse effects ; Follow-Up Studies ; COVID-19/prevention & control
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-10-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.o2527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.10: Show issues Location:
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  5. Article ; Online: US nutritionists call for dietary guideline limits on saturated fat intake to be lifted.

    Demasi, Maryanne

    BMJ (Clinical research ed.)

    2020  Volume 371, Page(s) m4226

    Language English
    Publishing date 2020-10-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m4226
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.10: Show issues Location:
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  6. Article ; Online: COVID-19 and metabolic syndrome: could diet be the key?

    Demasi, Maryanne

    BMJ evidence-based medicine

    2020  Volume 26, Issue 1, Page(s) 1–2

    MeSH term(s) COVID-19/epidemiology ; COVID-19/etiology ; Diet/adverse effects ; Humans ; Metabolic Syndrome/complications ; Metabolic Syndrome/epidemiology ; Risk Factors
    Keywords covid19
    Language English
    Publishing date 2020-07-10
    Publishing country England
    Document type Editorial
    ISSN 2515-4478
    ISSN (online) 2515-4478
    DOI 10.1136/bmjebm-2020-111451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Interventions to help patients withdraw from depression drugs: A systematic review.

    Gøtzsche, Peter C / Demasi, Maryanne

    The International journal of risk & safety in medicine

    2023  

    Abstract: Background: Depression drugs can be difficult to come off due to withdrawal symptoms. Gradual tapering with tapering support is needed to help patients withdraw safely.: Objective: To review the withdrawal success rates, using any intervention, and ... ...

    Abstract Background: Depression drugs can be difficult to come off due to withdrawal symptoms. Gradual tapering with tapering support is needed to help patients withdraw safely.
    Objective: To review the withdrawal success rates, using any intervention, and the effects on relapse/recurrence rates, symptom severity, quality of life, and withdrawal symptoms.
    Methods: Systematic review based on PubMed and Embase searches (last search 4 October 2022) of randomised trials with one or more treatment arms aimed at helping patients withdraw from a depression drug, regardless of indication for treatment. We calculated the mean and median success rates and the risk difference of depressive relapse when discontinuing or continuing depression drugs.
    Results: We included 13 studies (2085 participants). Three compared two withdrawal interventions and ten compared drug discontinuation vs. continuation. The success rates varied hugely between the trials (9% to 80%), with a weighted mean of 47% (95% confidence interval 38% to 57%) and a median of 50% (interquartile range 29% to 65%). A meta-regression showed that the length of taper was highly predictive for the risk of relapse (P = 0.00001). All the studies we reviewed confounded withdrawal symptoms with relapse; did not use hyperbolic tapering; withdrew the depression drug too fast in a linear fashion; and stopped it entirely when receptor occupancy was still high.
    Conclusion: The true proportion of patients on depression drugs who can stop safely without relapse is likely considerably higher than the 50% we found.
    Language English
    Publishing date 2023-09-13
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1055458-0
    ISSN 1878-6847 ; 0924-6479
    ISSN (online) 1878-6847
    ISSN 0924-6479
    DOI 10.3233/JRS-230011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3083: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: COVID-19 and metabolic syndrome

    Demasi, Maryanne

    BMJ Evidence-Based Medicine

    could diet be the key?

    2020  , Page(s) bmjebm–2020–111451

    Keywords covid19
    Language English
    Publisher BMJ
    Publishing country uk
    Document type Article ; Online
    ISSN 2515-446X
    DOI 10.1136/bmjebm-2020-111451
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article ; Online: The Fallacy of OTC Statin Therapy.

    Demasi, Maryanne / DuBroff, Robert

    Journal of the American College of Cardiology

    2021  Volume 78, Issue 25, Page(s) e325

    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2021-12-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2021.09.1380
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 196: Show issues

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