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  1. Article ; Online: Diabetic Hemichorea-Hemiballism.

    Pal, Rimesh / Bhadada, Sanjay K

    Neurology India

    2023  Volume 71, Issue 2, Page(s) 406–407

    MeSH term(s) Humans ; Dyskinesias/etiology ; Chorea/diagnostic imaging ; Chorea/etiology ; Diabetes Mellitus
    Language English
    Publishing date 2023-05-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.375388
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 698: Show issues Location:
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  2. Article: Giant multicystic ovaries in a young girl.

    Pal, Rimesh / Bhadada, Sanjay Kumar

    The Indian journal of medical research

    2022  Volume 152, Issue Suppl 1, Page(s) S89

    MeSH term(s) Female ; Humans ; Hypothyroidism ; Polycystic Ovary Syndrome/diagnostic imaging
    Language English
    Publishing date 2022-03-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_2142_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19, hypothalamo-pituitary-adrenal axis and clinical implications.

    Pal, Rimesh

    Endocrine

    2020  Volume 68, Issue 2, Page(s) 251–252

    MeSH term(s) Adrenal Glands/pathology ; Adrenal Glands/virology ; Adrenal Insufficiency/diagnosis ; Adrenal Insufficiency/mortality ; Adrenal Insufficiency/virology ; Adrenocorticotropic Hormone/blood ; Adult ; Aged ; Angiotensin-Converting Enzyme 2 ; Autopsy ; Betacoronavirus/pathogenicity ; Betacoronavirus/physiology ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/etiology ; Coronavirus Infections/mortality ; Coronavirus Infections/physiopathology ; Edema/complications ; Edema/pathology ; Edema/virology ; Female ; Humans ; Hydrocortisone/blood ; Hydrocortisone/deficiency ; Hypopituitarism/blood ; Hypopituitarism/mortality ; Hypopituitarism/physiopathology ; Hypopituitarism/virology ; Hypothalamo-Hypophyseal System/physiopathology ; Hypothalamo-Hypophyseal System/virology ; Hypothyroidism/blood ; Hypothyroidism/mortality ; Hypothyroidism/physiopathology ; Hypothyroidism/virology ; Infarction/complications ; Infarction/pathology ; Infarction/virology ; Male ; Middle Aged ; Pandemics ; Peptidyl-Dipeptidase A/physiology ; Pituitary-Adrenal System/physiopathology ; Pituitary-Adrenal System/virology ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/etiology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/physiopathology ; Prognosis ; SARS-CoV-2
    Chemical Substances Adrenocorticotropic Hormone (9002-60-2) ; Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) ; Hydrocortisone (WI4X0X7BPJ)
    Keywords covid19
    Language English
    Publishing date 2020-04-28
    Publishing country United States
    Document type Letter
    ZDB-ID 1194484-5
    ISSN 1559-0100 ; 1355-008X ; 0969-711X
    ISSN (online) 1559-0100
    ISSN 1355-008X ; 0969-711X
    DOI 10.1007/s12020-020-02325-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: AGEs accumulation with vascular complications, glycemic control and metabolic syndrome: A narrative review.

    Pal, Rimesh / Bhadada, Sanjay K

    Bone

    2023  Volume 176, Page(s) 116884

    Abstract: Background: Multiple pathogenetic mechanisms are involved in the genesis of various microvascular and macrovascular complications of diabetes mellitus. Of all these, advanced glycation end products (AGEs) have been strongly implicated.: Objectives: ... ...

    Abstract Background: Multiple pathogenetic mechanisms are involved in the genesis of various microvascular and macrovascular complications of diabetes mellitus. Of all these, advanced glycation end products (AGEs) have been strongly implicated.
    Objectives: The present narrative review aims to summarize the available literature on the genesis of AGEs and their potential role in the causation of both micro- and macrovascular complications of diabetes mellitus.
    Results: Uncontrolled hyperglycemia triggers the formation of AGEs through non-enzymatic glycation reactions between reducing sugars and proteins, lipids, or nucleic acids. AGEs accumulate in bloodstream and bodily tissues under chronic hyperglycemia. AGEs create irreversible cross-linkages of various intra- and extracellular molecules and activate the receptor for advanced glycation end products (RAGE), which stimulates downstream signaling pathways that generate reactive oxygen species (ROS) and contribute to oxidative stress. Additionally, intracellular glycation of mitochondrial respiratory chain proteins by AGEs contributes to the further generation of ROS, which, in turn, sets a vicious cycle that further promotes the production of endogenous AGEs. Through these pathways, AGEs play a principal role in the pathogenesis of various diabetic complications, including diabetic retinopathy, nephropathy, neuropathy, bone disease, atherosclerosis and non-alcoholic fatty liver disease. Multiple clinical studies and meta-analyses have revealed a positive association between tissue or circulating levels of AGEs and development of various diabetic complications. Besides, exogenous AGEs, primarily those derived from diets, promote insulin resistance, obesity, and metabolic syndrome.
    Conclusions: AGEs, triggered by chronic hyperglycemia, play a pivotal role in the pathogenesis of various complications of diabetes mellitus.
    MeSH term(s) Humans ; Metabolic Syndrome ; Glycemic Control ; Reactive Oxygen Species ; Hyperglycemia ; Cardiovascular Diseases ; Glycation End Products, Advanced
    Chemical Substances Reactive Oxygen Species ; Glycation End Products, Advanced
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 632515-4
    ISSN 1873-2763 ; 8756-3282
    ISSN (online) 1873-2763
    ISSN 8756-3282
    DOI 10.1016/j.bone.2023.116884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Woes of ethnic minority groups suffering from diabetes during the COVID-19 pandemic: high time to address the same.

    Prasad, Trupti N / Pal, Rimesh

    Evidence-based nursing

    2022  Volume 26, Issue 3, Page(s) 94

    MeSH term(s) Humans ; Ethnicity ; Minority Groups ; COVID-19 ; Ethnic and Racial Minorities ; Pandemics ; Diabetes Mellitus
    Language English
    Publishing date 2022-12-22
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1425988-6
    ISSN 1468-9618 ; 1367-6539
    ISSN (online) 1468-9618
    ISSN 1367-6539
    DOI 10.1136/ebnurs-2022-103629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5184: Show issues Location:
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  6. Article ; Online: Intercepting the deadly trinity of mucormycosis, diabetes and COVID-19 in India.

    Banerjee, Mainak / Pal, Rimesh / Bhadada, Sanjay K

    Postgraduate medical journal

    2023  Volume 98, Issue e2, Page(s) e108–e109

    MeSH term(s) Humans ; Mucormycosis/diagnosis ; Mucormycosis/epidemiology ; Mucormycosis/therapy ; COVID-19/epidemiology ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/therapy ; India/epidemiology
    Language English
    Publishing date 2023-04-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1136/postgradmedj-2021-140537
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  8. Article ; Online: COVID-19, hypothalamo-pituitary-adrenal axis and clinical implications

    Pal, Rimesh

    Endocrine

    2020  Volume 68, Issue 2, Page(s) 251–252

    Keywords covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1194484-5
    ISSN 1355-008X ; 0969-711X
    ISSN 1355-008X ; 0969-711X
    DOI 10.1007/s12020-020-02325-1
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Zs.A 3884: Show issues Location:
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  9. Article ; Online: GLP-1 receptor agonists, SGLT2 inhibitors and noncardiovascular mortality in type 2 diabetes: Insights from a meta-analysis.

    Banerjee, Mainak / Pal, Rimesh / Maisnam, Indira / Mukhopadhyay, Satinath

    Diabetes & metabolic syndrome

    2024  Volume 18, Issue 1, Page(s) 102943

    Abstract: Objective: Type-2 diabetes (T2D) poses a higher risk of noncardiovascular mortality in addition to the burden of cardiovascular mortality. The well-established cardiovascular benefits of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium- ... ...

    Abstract Objective: Type-2 diabetes (T2D) poses a higher risk of noncardiovascular mortality in addition to the burden of cardiovascular mortality. The well-established cardiovascular benefits of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) could solely explain their apparent effects on all-cause mortality in T2D. The present meta-analysis aims to pool their effects on noncardiovascular mortality in T2D and summarize the recent evidence on plausible pathways mediating these effects.
    Methods: PubMed, Embase, Web of Science, and clinical trial registries were searched for randomized controlled trials (RCTs) with ≥1-year duration in adults with T2D reporting both cardiovascular and all-cause mortality in treatment versus placebo arms (PROSPERO: CRD42022337559). Noncardiovascular mortality was calculated by subtracting cardiovascular mortality events from all-cause mortality and risk ratios (RRs) were calculated. Random-effects meta-analysis was done. GRADE framework was used to assess evidence quality.
    Results: We identified 17 eligible RCTs pooling data retrieved from 109,892 patients. Randomization to GLP-1 RA treatment versus placebo was associated with reduced noncardiovascular mortality (RR = 0.90; 95%CI: 0.81-0.99; I
    Conclusion: The impact of GLP-1RAs and SGLT2i on mortality in people with T2D extends beyond their cardiovascular benefits.
    MeSH term(s) Humans ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Glucagon-Like Peptide-1 Receptor Agonists ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/chemically induced ; Glucagon-Like Peptide 1 ; Cardiovascular Diseases/complications ; Glucagon-Like Peptide-1 Receptor/agonists ; Hypoglycemic Agents/therapeutic use
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors ; Glucagon-Like Peptide-1 Receptor Agonists ; Glucagon-Like Peptide 1 (89750-14-1) ; Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents
    Language English
    Publishing date 2024-01-05
    Publishing country Netherlands
    Document type Meta-Analysis ; Journal Article ; Review
    ZDB-ID 2273766-2
    ISSN 1878-0334 ; 1871-4021
    ISSN (online) 1878-0334
    ISSN 1871-4021
    DOI 10.1016/j.dsx.2024.102943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Glycemic Control in Youth-onset Type 2 Diabetes: Predicting the Tomorrow Based on Lessons Learnt from TODAY.

    Pal, Rimesh / Bhadada, Sanjay K

    The Journal of clinical endocrinology and metabolism

    2022  Volume 107, Issue 10, Page(s) e4252–e4253

    MeSH term(s) Adolescent ; Blood Glucose ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/therapy ; Glycated Hemoglobin A/analysis ; Glycemic Control ; Humans
    Chemical Substances Blood Glucose ; Glycated Hemoglobin A
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgac338
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