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  1. Article ; Online: Characterization of clinical presentation, histological features, ultrasonographic findings, and survival in 29 dogs with granulomatous hepatitis.

    Prentice, Kayla D / Callahan-Clark, Julie E / Parry, Nicola M / Schwarz, Leslie A / Webster, Cynthia R L

    Journal of veterinary internal medicine

    2023  Volume 38, Issue 1, Page(s) 167–175

    Abstract: Background: Granulomatous hepatitis (GH) is a form of chronic hepatitis (CH) in dogs for which limited information is published.: Hypothesis: Describe the clinical presentation, clinical pathology, ultrasound, and hepatic histopathology findings and ... ...

    Abstract Background: Granulomatous hepatitis (GH) is a form of chronic hepatitis (CH) in dogs for which limited information is published.
    Hypothesis: Describe the clinical presentation, clinical pathology, ultrasound, and hepatic histopathology findings and to report survival times in dogs with GH.
    Animals: Twenty-nine client-owned dogs with GH.
    Methods: Retrospective observational study. Pathology records were searched. Inclusion criteria included a histopathologic diagnosis of GH, absence of an identified etiology or evidence of extrahepatic granulomatous disease, and a medical record available for review. Clinical presentation, clinical pathologic findings, treatment protocols, and survival times were recorded. Available hepatic biopsy material was graded and scored, and ultrasound evaluations reviewed.
    Results: The median age was 7 years (range, 0.66-12 years). Nineteen breeds were represented. Decreased appetite (19/29), lethargy (16/29), and fever (13/29) were seen most commonly. All dogs had increased serum transaminase activities, whereas 21/29 and 12/24 had hyperbilirubinemia and neutrophilia, respectively. Ultrasonographic findings included hepatomegaly (12/22), nodular parenchymal lesions (9/22), and hyperechoic parenchymal bands (8/22). Histopathologic necroinflammatory scores were moderate to severe in 16/19 dogs, and fibrosis scores were mild in 14/19 dogs. Treatments varied and included antibiotics, immunosuppressive drugs, and hepatoprotectants. Overall median survival was 635 days (range, 1-2482 days).
    Conclusion and clinical importance: Granulomatous hepatitis in dogs is associated with high histopathologic grade, fever, neutrophilia, and a high incidence of hepatomegaly and focal parenchymal lesions on ultrasound examination. Despite disease severity on presentation, dogs with GH can have a good outcome with prolonged survival.
    MeSH term(s) Humans ; Dogs ; Animals ; Hepatomegaly/veterinary ; Dog Diseases/diagnostic imaging ; Dog Diseases/drug therapy ; Hepatitis, Chronic/veterinary ; Retrospective Studies
    Language English
    Publishing date 2023-11-23
    Publishing country United States
    Document type Observational Study, Veterinary ; Journal Article
    ZDB-ID 92798-3
    ISSN 1939-1676 ; 0891-6640
    ISSN (online) 1939-1676
    ISSN 0891-6640
    DOI 10.1111/jvim.16937
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 and pets: When pandemic meets panic.

    Parry, Nicola M A

    Forensic Science International. Reports

    2020  Volume 2, Page(s) 100090

    Abstract: As the novel coronavirus outbreak spreads globally with devastating effects on human health, pets are also becoming unnecessary victims amidst the pandemic panic. Many have been reluctantly left home alone by owners who have been forced to temporarily ... ...

    Abstract As the novel coronavirus outbreak spreads globally with devastating effects on human health, pets are also becoming unnecessary victims amidst the pandemic panic. Many have been reluctantly left home alone by owners who have been forced to temporarily evacuate their homes. And, although no evidence exists to indicate that they can either transmit the virus or develop its associated coronavirus disease 2019 (COVID-19), fear among the public that pets might play a role in spreading COVID-19 has resulted in pets being abandoned or even killed. This article outlines some of the ways in which the current pandemic has negatively impacted the welfare of pets. It also highlights the relationships between animal, human, and environmental health, as well as the importance of taking a collaborative transdisciplinary
    Language English
    Publishing date 2020-04-11
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2665-9107
    ISSN (online) 2665-9107
    DOI 10.1016/j.fsir.2020.100090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: COVID-19 and pets: When pandemic meets panic

    Parry, Nicola M.A.

    Foren. Sci. Internat. Rep.

    Abstract: As the novel coronavirus outbreak spreads globally with devastating effects on human health, pets are also becoming unnecessary victims amidst the pandemic panic. Many have been reluctantly left home alone by owners who have been forced to temporarily ... ...

    Abstract As the novel coronavirus outbreak spreads globally with devastating effects on human health, pets are also becoming unnecessary victims amidst the pandemic panic. Many have been reluctantly left home alone by owners who have been forced to temporarily evacuate their homes. And, although no evidence exists to indicate that they can either transmit the virus or develop its associated coronavirus disease 2019 (COVID-19), fear among the public that pets might play a role in spreading COVID-19 has resulted in pets being abandoned or even killed. This article outlines some of the ways in which the current pandemic has negatively impacted the welfare of pets. It also highlights the relationships between animal, human, and environmental health, as well as the importance of taking a collaborative transdisciplinary One Health approach to help prevent future COVID-19 outbreaks.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #46412
    Database COVID19

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  4. Article: COVID-19 and pets: When pandemic meets panic

    Parry, Nicola M.A

    Forensic science international. 2020 Dec., v. 2

    2020  

    Abstract: As the novel coronavirus outbreak spreads globally with devastating effects on human health, pets are also becoming unnecessary victims amidst the pandemic panic. Many have been reluctantly left home alone by owners who have been forced to temporarily ... ...

    Abstract As the novel coronavirus outbreak spreads globally with devastating effects on human health, pets are also becoming unnecessary victims amidst the pandemic panic. Many have been reluctantly left home alone by owners who have been forced to temporarily evacuate their homes. And, although no evidence exists to indicate that they can either transmit the virus or develop its associated coronavirus disease 2019 (COVID-19), fear among the public that pets might play a role in spreading COVID-19 has resulted in pets being abandoned or even killed. This article outlines some of the ways in which the current pandemic has negatively impacted the welfare of pets. It also highlights the relationships between animal, human, and environmental health, as well as the importance of taking a collaborative transdisciplinary One Health approach to help prevent future COVID-19 outbreaks.
    Keywords Coronavirus infections ; One Health initiative ; Orthocoronavirinae ; environmental health ; fearfulness ; forensic sciences ; human health ; humans ; pandemic ; pets ; viruses
    Language English
    Dates of publication 2020-12
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-light
    ISSN 2665-9107
    DOI 10.1016/j.fsir.2020.100090
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: COVID-19 and pets

    Parry, Nicola M.A.

    Forensic Science International: Reports

    When pandemic meets panic

    2020  Volume 2, Page(s) 100090

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2665-9107
    DOI 10.1016/j.fsir.2020.100090
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: COVID-19 and pets

    Nicola M.A. Parry

    Forensic Science International: Reports, Vol 2, Iss , Pp 100090- (2020)

    When pandemic meets panic

    2020  

    Abstract: As the novel coronavirus outbreak spreads globally with devastating effects on human health, pets are also becoming unnecessary victims amidst the pandemic panic. Many have been reluctantly left home alone by owners who have been forced to temporarily ... ...

    Abstract As the novel coronavirus outbreak spreads globally with devastating effects on human health, pets are also becoming unnecessary victims amidst the pandemic panic. Many have been reluctantly left home alone by owners who have been forced to temporarily evacuate their homes. And, although no evidence exists to indicate that they can either transmit the virus or develop its associated coronavirus disease 2019 (COVID-19), fear among the public that pets might play a role in spreading COVID-19 has resulted in pets being abandoned or even killed. This article outlines some of the ways in which the current pandemic has negatively impacted the welfare of pets. It also highlights the relationships between animal, human, and environmental health, as well as the importance of taking a collaborative transdisciplinary One Health approach to help prevent future COVID-19 outbreaks.
    Keywords Animal coronaviruses ; COVID-19 ; One health ; Pets ; SARS-CoV-2 ; Zoonotic disease ; Criminal law and procedure ; K5000-5582 ; covid19
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: The rise of veterinary forensics.

    Parry, Nicola M A / Stoll, Alexander

    Forensic science international

    2019  Volume 306, Page(s) 110069

    Abstract: Veterinary forensics is rapidly emerging as a distinct branch of veterinary medicine, especially because of increasing mindfulness about animal cruelty, and of the link between acts of cruelty to animals and violence toward humans. Nevertheless, the ... ...

    Abstract Veterinary forensics is rapidly emerging as a distinct branch of veterinary medicine, especially because of increasing mindfulness about animal cruelty, and of the link between acts of cruelty to animals and violence toward humans. Nevertheless, the application of forensic sciences in veterinary cases lags behind its application in medical cases. Although gaps persist in veterinarians' knowledge of forensics and in how to apply this field to medicolegal cases involving animals, continued research and publication in veterinary forensics are rapidly developing the evidence base in this area. Additionally, educational opportunities in veterinary forensics are also increasing at both undergraduate and postgraduate levels. Together, these changes will continue to improve veterinarians' abilities to investigate cases involving animals. To further strengthen these investigations, veterinarians should also collaborate with the appropriate experts in different disciplines of forensic science.
    MeSH term(s) Animal Welfare ; Animals ; Animals, Wild ; Conservation of Natural Resources ; Cooperative Behavior ; Crime ; Endangered Species ; Evidence-Based Medicine ; Forensic Medicine ; Humans ; Publishing ; Veterinarians ; Veterinary Medicine
    Language English
    Publishing date 2019-11-20
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 424042-x
    ISSN 1872-6283 ; 0379-0738
    ISSN (online) 1872-6283
    ISSN 0379-0738
    DOI 10.1016/j.forsciint.2019.110069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Over-celling fetal microbial exposure.

    Kennedy, Katherine M / Bellissimo, Christian J / Breznik, Jessica A / Barrett, Jon / Braun, Thorsten / Bushman, Frederic D / De Goffau, Marcus / Elovitz, Michal A / Heimesaat, Markus M / Konnikova, Liza / Koren, Omry / Parry, Samuel / Rossi, Laura / Segata, Nicola / Simmons, Rebecca A / Surette, Michael G / Walter, Jens / Sloboda, Deborah M

    Cell

    2021  Volume 184, Issue 24, Page(s) 5839–5841

    MeSH term(s) Female ; Fetus ; Humans ; Placenta ; Pregnancy
    Language English
    Publishing date 2021-11-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2021.10.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The rise of veterinary forensics

    Parry, Nicola M.A / Stoll, Alexander

    Forensic science international. 2020 Jan., v. 306

    2020  

    Abstract: Veterinary forensics is rapidly emerging as a distinct branch of veterinary medicine, especially because of increasing mindfulness about animal cruelty, and of the link between acts of cruelty to animals and violence toward humans. Nevertheless, the ... ...

    Abstract Veterinary forensics is rapidly emerging as a distinct branch of veterinary medicine, especially because of increasing mindfulness about animal cruelty, and of the link between acts of cruelty to animals and violence toward humans. Nevertheless, the application of forensic sciences in veterinary cases lags behind its application in medical cases. Although gaps persist in veterinarians’ knowledge of forensics and in how to apply this field to medicolegal cases involving animals, continued research and publication in veterinary forensics are rapidly developing the evidence base in this area. Additionally, educational opportunities in veterinary forensics are also increasing at both undergraduate and postgraduate levels. Together, these changes will continue to improve veterinarians’ abilities to investigate cases involving animals. To further strengthen these investigations, veterinarians should also collaborate with the appropriate experts in different disciplines of forensic science.
    Keywords animal welfare ; experts ; forensic sciences ; humans ; veterinarians ; veterinary medicine ; violence
    Language English
    Dates of publication 2020-01
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 424042-x
    ISSN 1872-6283 ; 0379-0738
    ISSN (online) 1872-6283
    ISSN 0379-0738
    DOI 10.1016/j.forsciint.2019.110069
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Outcome and Prognostic Factors in Cats Undergoing Resection of Intestinal Adenocarcinomas: 58 Cases (2008-2020).

    Czajkowski, Peter S / Parry, Nicola M / Wood, Carrie A / Casale, Sue A / Phipps, Whitney E / Mahoney, Jennifer A / Spector, Daniel I / Price, Lori Lyn / Berg, John

    Frontiers in veterinary science

    2022  Volume 9, Page(s) 911666

    Abstract: The purpose of this multi-institutional retrospective study was to expand the available data pertaining to pre-operative clinical findings, progression-free and overall survival times, and potential prognostic factors for cats undergoing surgery for ... ...

    Abstract The purpose of this multi-institutional retrospective study was to expand the available data pertaining to pre-operative clinical findings, progression-free and overall survival times, and potential prognostic factors for cats undergoing surgery for intestinal adenocarcinomas. Fifty-eight cats treated over a 12-year period were included in the study. Progression-free and overall survival times were estimated using Kaplan-Meier analyses. Potential prognostic variables were evaluated for associations with progression-free and overall survival using univariate Cox proportional hazards regression analyses. Prior to surgery, the intestinal mass was identified using ultrasonography in 89% of cats in which it was applied; however, imaging findings suggestive of intrathoracic metastases were observed in only 9% of cats. Among 22 cats undergoing ultrasound-guided fine needle aspiration cytology, the results agreed with the results of histopathology in only 10 cats. Discordant results were most commonly related to the presence of marked inflammation in cytology samples, which may have obscured the presence of neoplastic cells. Diffuse intestinal small cell lymphoma was identified as a comorbidity in 5 cats. Resection of the tumor with the objective of obtaining wide surgical margins was performed in each cat. On histopathology, 20 tumors were classified as mucinous adenocarcinoma and 28 were adenocarcinoma not otherwise specified. Intestinal transection site margins were complete in 94% of cats; however, complete mural margins were present in only 15% of cats. Local lymph node metastases were identified in 52% of cats and carcinomatosis was diagnosed in 81% of cats. Disease progression was documented in 32 of the 58 cats (55%). Of these 32 cats, 14 (43%) had local recurrence of the primary intestinal tumor. Median progression-free survival was 203 days (95% CI 130-299 days), and median overall survival time was 284 days (95% CI 200-363 days). Mitotic count was inversely associated with progression-free survival (HR 1.04; 95% CI 1.01-1.07,
    Language English
    Publishing date 2022-06-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2022.911666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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