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  1. Article: Exploring the Early-Life Microbiome and Future Risk of Inflammatory Bowel Disease.

    Ng, Siew C

    Gastroenterology & hepatology

    2023  Volume 19, Issue 11, Page(s) 693–696

    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply.

    Zhang, Fen / Ng, Siew C

    Gastroenterology

    2022  Volume 163, Issue 1, Page(s) 337–338

    Language English
    Publishing date 2022-03-31
    Publishing country United States
    Document type Letter
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2022.03.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Editorial: Faecal microbiota transplantation in IBS-Moving closer or away from success? Authors' reply.

    Su, Qi / Yau, Yuk K / Ng, Siew C

    Alimentary pharmacology & therapeutics

    2023  Volume 58, Issue 9, Page(s) 952–953

    MeSH term(s) Humans ; Fecal Microbiota Transplantation ; Irritable Bowel Syndrome/therapy ; Feces ; Microbiota
    Language English
    Publishing date 2023-10-13
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.17729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reply.

    Zhang, Lin / Chan, Francis K L / Ng, Siew C

    Gastroenterology

    2022  Volume 162, Issue 7, Page(s) 2135

    Language English
    Publishing date 2022-02-19
    Publishing country United States
    Document type Letter
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2022.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Early-life exposures and the microbiome: implications for IBD prevention.

    Zhang, Lin / Agrawal, Manasi / Ng, Siew C / Jess, Tine

    Gut

    2024  Volume 73, Issue 3, Page(s) 541–549

    Abstract: The early-life period is one of microbiome establishment and immune maturation. Early-life exposures are increasingly being recognised to play an important role in IBD risk. The composition of functions of the gut microbiome in the prenatal, perinatal, ... ...

    Abstract The early-life period is one of microbiome establishment and immune maturation. Early-life exposures are increasingly being recognised to play an important role in IBD risk. The composition of functions of the gut microbiome in the prenatal, perinatal, and postnatal period may be crucial towards development of health or disease, including IBD, later in life. We herein present a comprehensive summary of the interplay between early-life factors and microbiome perturbations, and their association with risk of IBD. In addition, we provide an overview of host and external factors in early life that are known to impact gut microbiome maturation and exposures implicated in IBD risk. Considering the emerging concept of IBD prevention, we propose strategies to minimise maternal and offspring exposure to potentially harmful variables and recommend protective measures during pregnancy and the postpartum period. This holistic view of early-life factors and microbiome signatures among mothers and their offspring will help frame our current understanding of their importance towards IBD pathogenesis and frame the roadmap for preventive strategies.
    MeSH term(s) Pregnancy ; Female ; Humans ; Inflammatory Bowel Diseases/prevention & control ; Microbiota ; Gastrointestinal Microbiome ; Postpartum Period ; Mothers
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2023-330002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reply.

    Zuo, Tao / Yeoh, Yun Kit / Ng, Siew C

    Gastroenterology

    2021  Volume 160, Issue 6, Page(s) 2193–2195

    Language English
    Publishing date 2021-01-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2021.01.196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Reply.

    Xu, Zhilu / Chan, Francis K L / Ng, Siew C

    Gastroenterology

    2021  Volume 160, Issue 6, Page(s) 2195–2196

    Language English
    Publishing date 2021-01-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2021.01.198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: COVID-19 and the gastrointestinal tract: more than meets the eye.

    Ng, Siew C / Tilg, Herbert

    Gut

    2020  Volume 69, Issue 6, Page(s) 973–974

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Diarrhea ; Gastrointestinal Tract ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-09
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2020-321195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Emerging Trends of Inflammatory Bowel Disease in Asia.

    Ng, Siew C

    Gastroenterology & hepatology

    2016  Volume 12, Issue 3, Page(s) 193–196

    Language English
    Publishing date 2016-04-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Promises of microbiome-based therapies.

    Bajaj, Jasmohan S / Ng, Siew C / Schnabl, Bernd

    Journal of hepatology

    2022  Volume 76, Issue 6, Page(s) 1379–1391

    Abstract: Humans harbour large quantities of microbes, including bacteria, fungi, viruses and archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota and gut barrier dysfunction. Preclinical models demonstrate the importance ... ...

    Abstract Humans harbour large quantities of microbes, including bacteria, fungi, viruses and archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota and gut barrier dysfunction. Preclinical models demonstrate the importance of the gut microbiota in the pathogenesis of various liver diseases. In this review, we discuss how manipulation of the gut microbiota can be used as a novel treatment approach for liver disease. We summarise current data on untargeted approaches, including probiotics and faecal microbiota transplantation, and precision microbiome-centered therapies, including engineered bacteria, postbiotics and phages, for the treatment of liver diseases.
    MeSH term(s) Bacteria ; Dysbiosis/microbiology ; Fecal Microbiota Transplantation ; Gastrointestinal Microbiome ; Humans ; Liver Diseases ; Microbiota ; Probiotics/therapeutic use
    Language English
    Publishing date 2022-04-20
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2021.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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