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  1. Article: COVID-19 and the state of food security in Africa.

    Mukiibi, Edward

    Agriculture and human values

    2020  , Page(s) 1–2

    Keywords covid19
    Language English
    Publishing date 2020-05-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 743547-2
    ISSN 1572-8366 ; 0889-048X
    ISSN (online) 1572-8366
    ISSN 0889-048X
    DOI 10.1007/s10460-020-10079-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 and the state of food security in Africa

    Mukiibi, Edward

    Agriculture and Human Values

    2020  Volume 37, Issue 3, Page(s) 627–628

    Keywords Agronomy and Crop Science ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 743547-2
    ISSN 1572-8366 ; 0889-048X
    ISSN (online) 1572-8366
    ISSN 0889-048X
    DOI 10.1007/s10460-020-10079-9
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Data Literacy

    Edward Mukiibi / Eliz Nassali State / Robert Stalone Buwule

    Journal of eScience Librarianship, Vol 12, Iss

    A catalyst for improving research publication productivity of Kyambogo University Academic Staff

    2023  Volume 2

    Abstract: Objective: The aim of this study is to explore how data literacy can influence the research and publications productivity of Kyambogo University academic staff.Methods: The study employed a literature review to collect detailed information. It observed ... ...

    Abstract Objective: The aim of this study is to explore how data literacy can influence the research and publications productivity of Kyambogo University academic staff.Methods: The study employed a literature review to collect detailed information. It observed lessons, and studied patterns of the phenomenon to explore data literacy initiatives that can be used by Kyambogo University academic staff to improve their research publications productivity and also to mitigate the accrued challenges.Results: The paper explored eight initiatives through which data literacy skills could enhance the research productivity of Kyambogo University academic staff. These were awareness and promoting freedom of using open data, engaging students in data literacy activities, pedagogical reflection, datafication of single and joint academic staff publications, visualization of data, storytelling, ethical use of data, and preservation of research data.Conclusions: While this paper relies on the context of the Kyambogo University academic staff, the authors posit that these data literacy skills can be embraced by universities in developing economies; especially those struggling with poor research and publications productivity. The paper further identifies areas where universities in developing economies, in conjunction with their libraries, can improve the academic staff pedagogy and compliance to eScience through polishing their data literacies.
    Keywords Data Literacy ; Research publications ; Kyambogo University ; Bibliography. Library science. Information resources ; Z
    Subject code 001
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher UMass Chan Medical School, Lamar Soutter Library
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Organochlorine pesticide residues in Uganda's honey as a bioindicator of environmental contamination and reproductive health implications to consumers.

    Ben Mukiibi, Stuart / Nyanzi, Steven Allan / Kwetegyeka, Justus / Olisah, Chijioke / Taiwo, Adewale Matthew / Mubiru, Edward / Tebandeke, Emmanuel / Matovu, Henry / Odongo, Silver / Abayi, Juma John Moses / Ngeno, Emily Chelangat / Sillanpää, Mika / Ssebugere, Patrick

    Ecotoxicology and environmental safety

    2021  Volume 214, Page(s) 112094

    Abstract: Honey has multifaceted nutritional and medicinal values; however, its quality is hinged on the floral origin of the nectar. Taking advantage of the large areas that they cover; honeybees are often used as bioindicators of environmental contamination. The ...

    Abstract Honey has multifaceted nutritional and medicinal values; however, its quality is hinged on the floral origin of the nectar. Taking advantage of the large areas that they cover; honeybees are often used as bioindicators of environmental contamination. The focus of the present paper was to examine the quality of honey from within the vicinity of an abandoned pesticide store in Masindi District in western Uganda. Surficial soils (<20 cm depths) and honey samples were collected from within the vicinity of the abandoned pesticide store and analysed for organochlorine pesticide (OCP) residues using gas chromatograph coupled to an electron capture detector (GC-ECD). The mean level of ∑DDTs in all the soil samples was 503.6 µg/kg dry weight (d.w). ∑DDTs contributed 92.2% to the ∑OCPs contamination loads in the soil samples, and others (lindane, aldrin, dieldrin, and endosulfans) contributed only 7.8%. Ratio (p, p'-DDE+p, p'-DDD)/p, p'-DDT of 1.54 suggested historical DDT input in the area. In all the honey samples, the mean level of ∑DDTs was 20.9 µg/kg. ∑DDTs contributed 43.3% to ∑OCPs contamination loads in the honey samples, followed by lindane (29.8%), endosulfans (23.6%) and dieldrin (3.2%), with corresponding mean levels of 14.4, 11.4 and 1.55 µg/kg, respectively. Reproductive risk assessment was done based on the hazard quotient (HQ) and hazard index (HI) procedure. In our study, the calculated HIs for adults (102.38), and children (90.33) suggested high potential health risks to the honey consumers. Lindane, endosulfan and p, p'-DDD detected in the honey samples at levels exceeding the acute reference dose (ARfD) are known risk factors for spontaneous abortion, reduced implantation, menstrual cycle shortening, impaired semen quality, and prostate cancer in exposed individuals and experimental animal models.
    MeSH term(s) Adult ; Aldrin/analysis ; Animals ; Child ; DDT/analysis ; Dichlorodiphenyl Dichloroethylene/analysis ; Dieldrin/analysis ; Dietary Exposure/statistics & numerical data ; Endosulfan/analysis ; Environmental Biomarkers ; Environmental Monitoring/methods ; Female ; Hexachlorocyclohexane/analysis ; Honey/analysis ; Humans ; Hydrocarbons, Chlorinated/analysis ; Male ; Pesticide Residues/analysis ; Pesticides/analysis ; Reproductive Health ; Semen Analysis ; Soil ; Uganda
    Chemical Substances Environmental Biomarkers ; Hydrocarbons, Chlorinated ; Pesticide Residues ; Pesticides ; Soil ; Dichlorodiphenyl Dichloroethylene (4M7FS82U08) ; Hexachlorocyclohexane (59NEE7PCAB) ; DDT (CIW5S16655) ; Dieldrin (I0246D2ZS0) ; Endosulfan (OKA6A6ZD4K) ; Aldrin (OZE3CLY605)
    Language English
    Publishing date 2021-03-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 436536-7
    ISSN 1090-2414 ; 0147-6513
    ISSN (online) 1090-2414
    ISSN 0147-6513
    DOI 10.1016/j.ecoenv.2021.112094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Food insecurity as a barrier to sustained antiretroviral therapy adherence in Uganda.

    Weiser, Sheri D / Tuller, David M / Frongillo, Edward A / Senkungu, Jude / Mukiibi, Nozmu / Bangsberg, David R

    PloS one

    2010  Volume 5, Issue 4, Page(s) e10340

    Abstract: Background: Food insecurity is emerging as an important barrier to antiretroviral (ARV) adherence in sub-Saharan Africa and elsewhere, but little is known about the mechanisms through which food insecurity leads to ARV non-adherence and treatment ... ...

    Abstract Background: Food insecurity is emerging as an important barrier to antiretroviral (ARV) adherence in sub-Saharan Africa and elsewhere, but little is known about the mechanisms through which food insecurity leads to ARV non-adherence and treatment interruptions.
    Methodology: We conducted in-depth, open-ended interviews with 47 individuals (30 women, 17 men) living with HIV/AIDS recruited from AIDS treatment programs in Mbarara and Kampala, Uganda to understand how food insecurity interferes with ARV therapy regimens. Interviews were transcribed, coded for key themes, and analyzed using grounded theory.
    Findings: Food insecurity was common and an important barrier to accessing medical care and ARV adherence. Five mechanisms emerged for how food insecurity can contribute to ARV non-adherence and treatment interruptions or to postponing ARV initiation: 1) ARVs increased appetite and led to intolerable hunger in the absence of food; 2) Side effects of ARVs were exacerbated in the absence of food; 3) Participants believed they should skip doses or not start on ARVs at all if they could not afford the added nutritional burden; 4) Competing demands between costs of food and medical expenses led people either to default from treatment, or to give up food and wages to get medications; 5) While working for food for long days in the fields, participants sometimes forgot medication doses. Despite these obstacles, many participants still reported high ARV adherence and exceptional motivation to continue therapy.
    Conclusions: While reports from sub-Saharan Africa show excellent adherence to ARVs, concerns remain that these successes are not sustainable in the presence of widespread poverty and food insecurity. We provide further evidence on how food insecurity can compromise sustained ARV therapy in a resource-limited setting. Addressing food insecurity as part of emerging ARV treatment programs is critical for their long-term success.
    MeSH term(s) Acquired Immunodeficiency Syndrome/drug therapy ; Anti-Retroviral Agents/therapeutic use ; Data Collection ; Drug Costs ; Female ; Food Supply/economics ; Food Supply/statistics & numerical data ; HIV Infections/drug therapy ; Humans ; Hunger/drug effects ; Male ; Medication Adherence/statistics & numerical data ; Patient Compliance/statistics & numerical data ; Poverty ; Uganda
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2010-04-28
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0010340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Food insecurity as a barrier to sustained antiretroviral therapy adherence in Uganda.

    Sheri D Weiser / David M Tuller / Edward A Frongillo / Jude Senkungu / Nozmu Mukiibi / David R Bangsberg

    PLoS ONE, Vol 5, Iss 4, p e

    2010  Volume 10340

    Abstract: Food insecurity is emerging as an important barrier to antiretroviral (ARV) adherence in sub-Saharan Africa and elsewhere, but little is known about the mechanisms through which food insecurity leads to ARV non-adherence and treatment interruptions.We ... ...

    Abstract Food insecurity is emerging as an important barrier to antiretroviral (ARV) adherence in sub-Saharan Africa and elsewhere, but little is known about the mechanisms through which food insecurity leads to ARV non-adherence and treatment interruptions.We conducted in-depth, open-ended interviews with 47 individuals (30 women, 17 men) living with HIV/AIDS recruited from AIDS treatment programs in Mbarara and Kampala, Uganda to understand how food insecurity interferes with ARV therapy regimens. Interviews were transcribed, coded for key themes, and analyzed using grounded theory.Food insecurity was common and an important barrier to accessing medical care and ARV adherence. Five mechanisms emerged for how food insecurity can contribute to ARV non-adherence and treatment interruptions or to postponing ARV initiation: 1) ARVs increased appetite and led to intolerable hunger in the absence of food; 2) Side effects of ARVs were exacerbated in the absence of food; 3) Participants believed they should skip doses or not start on ARVs at all if they could not afford the added nutritional burden; 4) Competing demands between costs of food and medical expenses led people either to default from treatment, or to give up food and wages to get medications; 5) While working for food for long days in the fields, participants sometimes forgot medication doses. Despite these obstacles, many participants still reported high ARV adherence and exceptional motivation to continue therapy.While reports from sub-Saharan Africa show excellent adherence to ARVs, concerns remain that these successes are not sustainable in the presence of widespread poverty and food insecurity. We provide further evidence on how food insecurity can compromise sustained ARV therapy in a resource-limited setting. Addressing food insecurity as part of emerging ARV treatment programs is critical for their long-term success.
    Keywords Medicine ; R ; Science ; Q
    Subject code 360 ; 590
    Language English
    Publishing date 2010-04-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Audio / Video: Food Insecurity as a Barrier to Sustained Antiretroviral Therapy Adherence in Uganda

    Weiser, Sheri D / Tuller, David M / Frongillo, Edward A / Senkungu, Jude / Mukiibi, Nozmu / Bangsberg, David R

    PloS one. 2010 Apr., v. 5, no. 4

    2010  

    Abstract: Background: Food insecurity is emerging as an important barrier to antiretroviral (ARV) adherence in sub-Saharan Africa and elsewhere, but little is known about the mechanisms through which food insecurity leads to ARV non-adherence and treatment ... ...

    Abstract Background: Food insecurity is emerging as an important barrier to antiretroviral (ARV) adherence in sub-Saharan Africa and elsewhere, but little is known about the mechanisms through which food insecurity leads to ARV non-adherence and treatment interruptions. Methodology: We conducted in-depth, open-ended interviews with 47 individuals (30 women, 17 men) living with HIV/AIDS recruited from AIDS treatment programs in Mbarara and Kampala, Uganda to understand how food insecurity interferes with ARV therapy regimens. Interviews were transcribed, coded for key themes, and analyzed using grounded theory. Findings: Food insecurity was common and an important barrier to accessing medical care and ARV adherence. Five mechanisms emerged for how food insecurity can contribute to ARV non-adherence and treatment interruptions or to postponing ARV initiation: 1) ARVs increased appetite and led to intolerable hunger in the absence of food; 2) Side effects of ARVs were exacerbated in the absence of food; 3) Participants believed they should skip doses or not start on ARVs at all if they could not afford the added nutritional burden; 4) Competing demands between costs of food and medical expenses led people either to default from treatment, or to give up food and wages to get medications; 5) While working for food for long days in the fields, participants sometimes forgot medication doses. Despite these obstacles, many participants still reported high ARV adherence and exceptional motivation to continue therapy. Conclusions: While reports from sub-Saharan Africa show excellent adherence to ARVs, concerns remain that these successes are not sustainable in the presence of widespread poverty and food insecurity. We provide further evidence on how food insecurity can compromise sustained ARV therapy in a resource-limited setting. Addressing food insecurity as part of emerging ARV treatment programs is critical for their long-term success.
    Language English
    Dates of publication 2010-04
    Document type Article ; Audio / Video
    ZDB-ID 2267670-3
    ISSN 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0010340
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Iron overload in Africa. Interaction between a gene and dietary iron content.

    Gordeuk, V / Mukiibi, J / Hasstedt, S J / Samowitz, W / Edwards, C Q / West, G / Ndambire, S / Emmanual, J / Nkanza, N / Chapanduka, Z

    The New England journal of medicine

    1992  Volume 326, Issue 2, Page(s) 95–100

    Abstract: Background and methods: In contrast to hemochromatosis, which in white populations is inherited through a gene linked to the HLA locus, iron overload in sub-Saharan Africa is believed to result solely from increased dietary iron derived from traditional ...

    Abstract Background and methods: In contrast to hemochromatosis, which in white populations is inherited through a gene linked to the HLA locus, iron overload in sub-Saharan Africa is believed to result solely from increased dietary iron derived from traditional home-brewed beer. To examine the hypothesis that African iron overload also involves a genetic factor, we used likelihood analysis to test for an interaction between a gene (the hypothesized iron-loading locus) and an environmental factor (increased dietary iron) that determines transferrin saturation and unsaturated iron-binding capacity. We studied 236 members of 36 African families chosen because they contained index subjects with iron overload. Linkage to the HLA region was tested with use of lod scores.
    Results: In the index subjects, increased iron was present in both hepatocytes and cells of the mononuclear-phagocyte system. Among family members with increased dietary iron due to the consumption of traditional beer, transferrin saturation in serum was distributed bimodally, with 56 normal values (less than 60 percent saturation) and 44 elevated values; the mean serum ferritin concentration was five times higher in the subjects with elevated transferrin saturation (P less than 0.005). The pedigree analysis provided evidence of both a genetic effect (P less than 0.005) and an effect of increased dietary iron (P less than 0.005) on transferrin saturation and unsaturated iron-binding capacity. In the most likely model, increased dietary iron raised the mean transferrin saturation from 30 to 81 percent and lowered the mean unsaturated iron-binding capacity from 38 to 13 mumol per liter in subjects heterozygous for the iron-loading locus. The hypothesis of tight linkage to HLA was rejected.
    Conclusions: Iron overload in Africa may be caused by an interaction between the amount of dietary iron and a gene distinct from any HLA-linked gene.
    MeSH term(s) Adult ; Africa, Central ; Africa, Southern ; Aged ; Beer/adverse effects ; Diet/adverse effects ; Family ; Female ; Genetic Linkage ; HLA Antigens ; Hemosiderosis/etiology ; Hemosiderosis/genetics ; Humans ; Iron/adverse effects ; Iron/analysis ; Iron/metabolism ; Liver/chemistry ; Male ; Middle Aged ; Transferrin/analysis
    Chemical Substances HLA Antigens ; Transferrin ; Iron (E1UOL152H7)
    Language English
    Publishing date 1992-01-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJM199201093260204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Iron overload in Africa: Interaction between a gene and dietary iron content

    Gordeuk, V / Mukiibi, J / Hasstedt, S.J / Samowitz, W / Edwards, C.Q / West, G / Ndambire, S / Emmanual, J / Nkanza, N / Chapanduka, Z

    New England journal of medicine. Jan 9, 1992. v. 326 (2)

    1992  

    Abstract: Background and Methods. In contrast to hemochromatosis, which in white populations is inherited through a gene linked to the HLA locus, iron overload in sub-Saharan Africa is believed to result solely from increased dietary iron derived from traditional ... ...

    Abstract Background and Methods. In contrast to hemochromatosis, which in white populations is inherited through a gene linked to the HLA locus, iron overload in sub-Saharan Africa is believed to result solely from increased dietary iron derived from traditional home-brewed beer. To examine the hypothesis that African iron overload also involves a genetic factor, we used likelihood analysis to test for an interaction between a gene (the hypothesized iron-loading locus) and an environmental factor (increased dietary iron) that determines transferrin saturation and unsaturated iron-binding capacity. We studied 236 members of 36 African families chosen because they contained index subjects with iron overload. Linkage to the HLA region was tested with use of lod scores. Results. In the index subjects, increased iron was present in both hepatocytes and cells of the mononuclearphagocyte system. Among family members with increased dietary iron due to the consumption of traditional beer, transferrin saturation in serum was distributed bimodally, with 56 normal values (<60 percent saturation) and 44 elevated values; the mean serum ferritin concentration was five times higher in the subjects with elevated transferrin saturation (P<0.005). The pedigree analysis provided evidence of both a genetic effect (P<0.005) and an effect of increased dietary iron (P<0.005) on transferrin saturation and unsaturated iron-binding capacity. In the most likely model, increased dietary iron raised the mean transferrin saturation from 30 to 81 percent and lowered the mean unsaturated iron-binding capacity from 38 to 13 micromoles per liter in subjects heterozygous for the iron-loading locus. The hypothesis of tight linkage to HLA was rejected. Conclusions. Iron overload in Africa may be caused by an interaction between the amount of dietary iron and a gene distinct from any HLA-linked gene.
    Keywords iron ; hemochromatosis ; nutrition-genotype interaction ; beers ; dietary minerals ; blood serum ; transferrin ; genetic techniques and protocols ; liver diseases ; hepatocytes ; women ; men ; ferritin ; Africa
    Language English
    Dates of publication 1992-0109
    Size p. 95-100.
    Document type Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    Database NAL-Catalogue (AGRICOLA)

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