LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 55

Search options

  1. Article ; Online: Reply to Cimolai: Post-COVID syndrome and autoimmunity.

    Acosta-Ampudia, Yeny / Anaya, Juan Manuel

    The Journal of infectious diseases

    2022  Volume 226, Issue 4, Page(s) 753–754

    MeSH term(s) Autoantibodies ; Autoimmune Diseases ; Autoimmunity ; COVID-19 ; Humans ; Lymphocyte Activation
    Chemical Substances Autoantibodies
    Language English
    Publishing date 2022-03-21
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiac106
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.50: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 445: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: How Important Is the Assessment of Soluble ACE-2 in COVID-19?

    Rojas, Manuel / Acosta-Ampudia, Yeny / Monsalve, Diana M / Ramírez-Santana, Carolina / Anaya, Juan-Manuel

    American journal of hypertension

    2022  Volume 34, Issue 3, Page(s) 296–297

    MeSH term(s) Aldosterone ; Angiotensin II ; Angiotensin-Converting Enzyme 2 ; COVID-19 ; Humans ; SARS-CoV-2
    Chemical Substances Angiotensin II (11128-99-7) ; Aldosterone (4964P6T9RB) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2022-01-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639383-4
    ISSN 1941-7225 ; 1879-1905 ; 0895-7061
    ISSN (online) 1941-7225 ; 1879-1905
    ISSN 0895-7061
    DOI 10.1093/ajh/hpaa178
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2329: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Metabolic fingerprinting of systemic sclerosis: a systematic review.

    Morales-González, Victoria / Galeano-Sánchez, Daniel / Covaleda-Vargas, Jaime Enrique / Rodriguez, Yhojan / Monsalve, Diana M / Pardo-Rodriguez, Daniel / Cala, Mónica P / Acosta-Ampudia, Yeny / Ramírez-Santana, Carolina

    Frontiers in molecular biosciences

    2023  Volume 10, Page(s) 1215039

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-08-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2023.1215039
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Persistent Autoimmune Activation and Proinflammatory State in Post-Coronavirus Disease 2019 Syndrome.

    Acosta-Ampudia, Yeny / Monsalve, Diana M / Rojas, Manuel / Rodríguez, Yhojan / Zapata, Elizabeth / Ramírez-Santana, Carolina / Anaya, Juan-Manuel

    The Journal of infectious diseases

    2022  Volume 225, Issue 12, Page(s) 2155–2162

    Abstract: Background: The immunopathological pathways enabling post-coronavirus disease 2019 (COVID-19) syndrome (PCS) development are not entirely known. We underwent a longitudinal analysis of patients with COVID-19 who developed PCS aiming to evaluate the ... ...

    Abstract Background: The immunopathological pathways enabling post-coronavirus disease 2019 (COVID-19) syndrome (PCS) development are not entirely known. We underwent a longitudinal analysis of patients with COVID-19 who developed PCS aiming to evaluate the autoimmune and immunological status associated with this condition.
    Methods: Thirty-three patients were included for longitudinal clinical and autoantibody analyses, 12 of whom were assessed for cytokines and lymphocyte populations. Patients were followed for 7-11 months after acute COVID-19. Autoimmune profile and immunological statuses were evaluated mainly by enzyme-linked-immunosorbent assays and flow cytometry.
    Results: Latent autoimmunity and overt autoimmunity persisted over time. A proinflammatory state was observed in patients with PCS characterized by up-regulated interferon-α, tumor necrosis factor-α, granulocyte colony-stimulating factor (G-CSF), interleukin (IL)-17A, IL-6, IL-1β, and IL-13, whereas interferon-γ-induced protein 10 (IP-10) was decreased. In addition, PCS was characterized by increased levels of Th9, CD8+ effector T cells, naive B cells, and CD4+ effector memory T cells. Total levels of immunoglobulin G S1-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies remained elevated over time.
    Conclusions: The clinical manifestations of PCS are associated with the persistence of a proinflammatory and effector phenotype induced by SARS-CoV-2 infection. This long-term persistent immune activation may contribute to the development of latent and overt autoimmunity. Results suggest the need to evaluate the role of immunomodulation in the treatment of PCS.
    MeSH term(s) Autoimmunity ; COVID-19/complications ; Cytokines ; Humans ; Inflammation ; Interferon-gamma ; SARS-CoV-2
    Chemical Substances Cytokines ; Interferon-gamma (82115-62-6)
    Language English
    Publishing date 2022-01-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiac017
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.50: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 445: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Autoimmunity is a hallmark of post-COVID syndrome.

    Rojas, Manuel / Rodríguez, Yhojan / Acosta-Ampudia, Yeny / Monsalve, Diana M / Zhu, Chengsong / Li, Quan-Zhen / Ramírez-Santana, Carolina / Anaya, Juan-Manuel

    Journal of translational medicine

    2022  Volume 20, Issue 1, Page(s) 129

    Abstract: Autoimmunity has emerged as a characteristic of the post-COVID syndrome (PCS), which may be related to sex. In order to further investigate the relationship between SARS-CoV-2 and autoimmunity in PCS, a clinical and serological assessment on 100 patients ...

    Abstract Autoimmunity has emerged as a characteristic of the post-COVID syndrome (PCS), which may be related to sex. In order to further investigate the relationship between SARS-CoV-2 and autoimmunity in PCS, a clinical and serological assessment on 100 patients was done. Serum antibody profiles against self-antigens and infectious agents were evaluated by an antigen array chip for 116 IgG and 104 IgM antibodies. Thirty pre-pandemic healthy individuals were included as a control group. The median age of patients was 49 years (IQR: 37.8 to 55.3). There were 47 males. The median post-COVID time was 219 (IQR: 143 to 258) days. Latent autoimmunity and polyautoimmunity were found in 83% and 62% of patients, respectively. Three patients developed an overt autoimmune disease. IgG antibodies against IL-2, CD8B, and thyroglobulin were found in more than 10% of the patients. Other IgG autoantibodies, such as anti-interferons, were positive in 5-10% of patients. Anti-SARS-CoV-2 IgG antibodies were found in > 85% of patients and were positively correlated with autoantibodies, age, and body mass index (BMI). Few autoantibodies were influenced by age and BMI. There was no effect of gender on the over- or under-expression of autoantibodies. IgG anti-IFN-λ antibodies were associated with the persistence of respiratory symptoms. In summary, autoimmunity is characteristic of PCS, and latent autoimmunity correlates with humoral response to SARS-CoV-2.
    MeSH term(s) Adult ; Antibodies, Viral/blood ; Autoimmunity ; COVID-19 ; Humans ; Immunoglobulin M/blood ; Male ; Middle Aged ; SARS-CoV-2
    Chemical Substances Antibodies, Viral ; Immunoglobulin M
    Language English
    Publishing date 2022-03-16
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2118570-0
    ISSN 1479-5876 ; 1479-5876
    ISSN (online) 1479-5876
    ISSN 1479-5876
    DOI 10.1186/s12967-022-03328-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Identifying the culprits in neurological autoimmune diseases.

    Acosta-Ampudia, Yeny / Monsalve, Diana M / Ramírez-Santana, Carolina

    Journal of translational autoimmunity

    2019  Volume 2, Page(s) 100015

    Abstract: The target organ of neurological autoimmune diseases (NADs) is the central or peripheral nervous system. Multiple sclerosis (MS) is the most common NAD, whereas Guillain-Barré syndrome (GBS), myasthenia gravis (MG), and neuromyelitis optica (NMO) are ... ...

    Abstract The target organ of neurological autoimmune diseases (NADs) is the central or peripheral nervous system. Multiple sclerosis (MS) is the most common NAD, whereas Guillain-Barré syndrome (GBS), myasthenia gravis (MG), and neuromyelitis optica (NMO) are less common NADs, but the incidence of these diseases has increased exponentially in the last few years. The identification of a specific culprit in NADs is challenging since a myriad of triggering factors interplay with each other to cause an autoimmune response. Among the factors that have been associated with NADs are genetic susceptibility, epigenetic mechanisms, and environmental factors such as infection, microbiota, vitamins, etc. This review focuses on the most studied culprits as well as the mechanisms used by these to trigger NADs.
    Language English
    Publishing date 2019-09-06
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2589-9090
    ISSN (online) 2589-9090
    DOI 10.1016/j.jtauto.2019.100015
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Comment on: Nature and Dimensions of the Systemic Hyper-inflammation and Its Attenuation by Convalescent Plasma in Severe COVID-19.

    Acosta-Ampudia, Yeny / Rojas, Manuel / Monsalve, Diana M / Rodríguez, Yhojan / Ramírez-Santana, Carolina / Anaya, Juan-Manuel

    The Journal of infectious diseases

    2021  Volume 223, Issue 10, Page(s) 1833–1834

    Language English
    Publishing date 2021-03-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiab137
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.50: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 445: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Predictors of mortality in hospitalised patients with COVID-19: a 1-year case-control study.

    Camacho-Domínguez, Laura / Rojas, Manuel / Herrán, María / Rodríguez, Yhojan / Beltrán, Santiago / Galindo, Paola Saboya / Aguirre-Correal, Nicolas / Espitia, María / García, Santiago / Bejarano, Valeria / Morales-González, Victoria / Covaleda-Vargas, Jaime Enrique / Rodríguez-Jiménez, Mónica / Zapata, Elizabeth / Monsalve, Diana M / Acosta-Ampudia, Yeny / Anaya, Juan-Manuel / Ramírez-Santana, Carolina

    BMJ open

    2024  Volume 14, Issue 2, Page(s) e072784

    Abstract: Background: A paucity of predictive models assessing risk factors for COVID-19 mortality that extend beyond age and gender in Latino population is evident in the current academic literature.: Objectives: To determine the associated factors with ... ...

    Abstract Background: A paucity of predictive models assessing risk factors for COVID-19 mortality that extend beyond age and gender in Latino population is evident in the current academic literature.
    Objectives: To determine the associated factors with mortality, in addition to age and sex during the first year of the pandemic.
    Design: A case-control study with retrospective revision of clinical and paraclinical variables by systematic revision of clinical records was conducted. Multiple imputations by chained equation were implemented to account for missing variables. Classification and regression trees (CART) were estimated to evaluate the interaction of associated factors on admission and their role in predicting mortality during hospitalisation. No intervention was performed.
    Setting: High-complexity centre above 2640 m above sea level (masl) in Colombia.
    Participants: A population sample of 564 patients admitted to the hospital with confirmed COVID-19 by PCR. Deceased patients (n=282) and a control group (n=282), matched by age, sex and month of admission, were included.
    Main outcome measure: Mortality during hospitalisation.
    Main results: After the imputation of datasets, CART analysis estimated 11 clinical profiles based on respiratory distress, haemoglobin, lactate dehydrogenase, partial pressure of oxygen to inspired partial pressure of oxygen ratio, chronic kidney disease, ferritin, creatinine and leucocytes on admission. The accuracy model for prediction was 80.4% (95% CI 71.8% to 87.3%), with an area under the curve of 78.8% (95% CI 69.63% to 87.93%).
    Conclusions: This study discloses new interactions between clinical and paraclinical features beyond age and sex influencing mortality in COVID-19 patients. Furthermore, the predictive model could offer new clues for the personalised management of this condition in clinical settings.
    MeSH term(s) Humans ; COVID-19 ; Case-Control Studies ; SARS-CoV-2 ; Retrospective Studies ; Oxygen ; Hospital Mortality
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-072784
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: How important is the assessment of soluble ACE-2 in COVID-19?

    Rojas, Manuel / Acosta-Ampudia, Yeny / M. Monsalve, Diana / Ramírez-Santana, Carolina / Anaya, Juan-Manuel

    American Journal of Hypertension ; ISSN 0895-7061 1941-7225

    2020  

    Keywords Internal Medicine ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    DOI 10.1093/ajh/hpaa178
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Latent autoimmune thyroid disease.

    Rodríguez, Yhojan / Rojas, Manuel / Monsalve, Diana M / Acosta-Ampudia, Yeny / Pacheco, Yovana / Rodríguez-Jiménez, Mónica / Ramírez-Santana, Carolina / Anaya, Juan-Manuel

    Journal of translational autoimmunity

    2020  Volume 3, Page(s) 100038

    Abstract: Objective: To determine the prevalence of thyroid autoantibodies and the associated factors in euthyroid subjects.: Methods: 300 euthyroid subjects, chosen by stratified sampling from an inception cohort of 1335 individuals, were included. Thyroid ... ...

    Abstract Objective: To determine the prevalence of thyroid autoantibodies and the associated factors in euthyroid subjects.
    Methods: 300 euthyroid subjects, chosen by stratified sampling from an inception cohort of 1335 individuals, were included. Thyroid function was evaluated by measuring the serum levels of TSH (0.3-4.5 μIU/mL) and FT4 (5.2-12.7μg/dL). Anti-peroxidase (TPOAbs), anti-thyroglobulin (TgAbs), and anti-TSH receptor (TrAbs) antibodies were evaluated with 23 additional autoantibodies as well as vitamin D (VitD) levels. The analysis included sociodemographic, clinical, and environmental characteristics. Data were analyzed by bivariate and multivariate tests.
    Results: Thyroid autoimmunity was observed in 15.3% of the subjects (TPOAbs 11.3% and TgAbs 2.0%). In six individuals, both autoantibodies were positive. TrAbs were not detected in any individual. Familial thyroid disease (β ​= ​3.4, 95% CI: 1.2-9.5,
    Conclusion: Latent thyroid autoimmunity is not rare. Environmental, genetic, and immunological factors as well as ancestry are associated risk factors. These results would facilitate the implementation of screening strategies in order to provide timely diagnosis and treatment.
    Language English
    Publishing date 2020-01-08
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2589-9090
    ISSN (online) 2589-9090
    DOI 10.1016/j.jtauto.2020.100038
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top