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  1. Article ; Online: Commentary: Thyroid eye disease-does the profile differ in India?

    Grover, Ashok Kumar

    Indian journal of ophthalmology

    2020  Volume 68, Issue 8, Page(s) 1635

    MeSH term(s) Graves Ophthalmopathy/diagnosis ; Graves Ophthalmopathy/epidemiology ; Humans ; India/epidemiology ; Severity of Illness Index
    Language English
    Publishing date 2020-07-22
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_2274_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 329: Show issues Location:
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  2. Article ; Online: COVID-19 crisis and residency education: A moment to seize the opportunity and create a new road map!

    Grover, Ashok Kumar

    Indian journal of ophthalmology

    2020  Volume 68, Issue 6, Page(s) 959–960

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; India ; Internship and Residency ; Ophthalmology ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Surveys and Questionnaires
    Keywords covid19
    Language English
    Publishing date 2020-05-27
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_1498_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19 crisis and residency education

    Ashok Kumar Grover

    Indian Journal of Ophthalmology, Vol 68, Iss 6, Pp 959-

    A moment to seize the opportunity and create a new road map!

    2020  Volume 960

    Keywords Ophthalmology ; RE1-994 ; covid19
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Residency training in India: Time for a course correction.

    Grover, Ashok Kumar

    Indian journal of ophthalmology

    2018  Volume 66, Issue 6, Page(s) 743–744

    MeSH term(s) Clinical Competence ; Education, Medical, Graduate/methods ; Humans ; India ; Internship and Residency/methods ; Ophthalmology/education
    Language English
    Publishing date 2018
    Publishing country India
    Document type Editorial
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_328_18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Management of nasolacrimal duct obstruction in children: How is it changing?

    Grover, Ashok Kumar

    Indian journal of ophthalmology

    2017  Volume 65, Issue 10, Page(s) 910–911

    Language English
    Publishing date 2017-10
    Publishing country India
    Document type Editorial
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_719_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Host-microbe interaction and pathogen exclusion mediated by an aggregation-prone surface layer protein of Lactobacillus helveticus.

    Choudhary, Ritu / Singh, Kumar Siddharth / Bisht, Sonu / Kumar, Sudarshan / Mohanty, Ashok Kumar / Grover, Sunita / Kaushik, Jai Kumar

    International journal of biological macromolecules

    2023  Volume 244, Page(s) 125146

    Abstract: Probiotic surface layer proteins (Slps) have multiple functions and bacterial adhesion to host cells is one of them. The precise role of Slps in cellular adhesion is not well understood due to its low native protein yield and self-aggregative nature. ... ...

    Abstract Probiotic surface layer proteins (Slps) have multiple functions and bacterial adhesion to host cells is one of them. The precise role of Slps in cellular adhesion is not well understood due to its low native protein yield and self-aggregative nature. Here, we report the recombinant expression and purification of biologically active Slp of Lactobacillus helveticus NCDC 288 (SlpH) in high yield. SlpH is a highly basic protein (pI = 9.4), having a molecular weight of 45 kDa. Circular Dichroism showed a prevalence of beta-strands in SlpH structure and resistance to low pH. SlpH showed binding to human intestinal tissue, enteric Caco-2 cell line, and porcine gastric mucin, but not with fibronectin, collagen type IV and laminin. SlpH inhibited the binding of the enterotoxigenic E. coli by 70 % and 76 % and that of Salmonella Typhimurium SL1344 by 71 % and 75 % to enteric Caco-2 cell line in the exclusion and competition assays, respectively. The pathogen exclusion and competition activity and tolerance to harsh gastrointestinal conditions show the potential for developing SlpH as a prophylactic or therapeutic agent against enteric pathogens.
    MeSH term(s) Animals ; Humans ; Swine ; Membrane Proteins ; Lactobacillus helveticus/genetics ; Escherichia coli ; Caco-2 Cells ; Host Microbial Interactions ; Bacterial Adhesion ; Probiotics/metabolism
    Chemical Substances S-layer proteins ; Membrane Proteins
    Language English
    Publishing date 2023-06-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.125146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Host-microbe interaction and pathogen exclusion mediated by an aggregation-prone surface layer protein of Lactobacillus helveticus

    Choudhary, Ritu / Singh, Kumar Siddharth / Bisht, Sonu / Kumar, Sudarshan / Mohanty, Ashok Kumar / Grover, Sunita / Kaushik, Jai Kumar

    International Journal of Biological Macromolecules. 2023 July, v. 244 p.125146-

    2023  

    Abstract: Probiotic surface layer proteins (Slps) have multiple functions and bacterial adhesion to host cells is one of them. The precise role of Slps in cellular adhesion is not well understood due to its low native protein yield and self-aggregative nature. ... ...

    Abstract Probiotic surface layer proteins (Slps) have multiple functions and bacterial adhesion to host cells is one of them. The precise role of Slps in cellular adhesion is not well understood due to its low native protein yield and self-aggregative nature. Here, we report the recombinant expression and purification of biologically active Slp of Lactobacillus helveticus NCDC 288 (SlpH) in high yield. SlpH is a highly basic protein (pI = 9.4), having a molecular weight of 45 kDa. Circular Dichroism showed a prevalence of beta-strands in SlpH structure and resistance to low pH. SlpH showed binding to human intestinal tissue, enteric Caco-2 cell line, and porcine gastric mucin, but not with fibronectin, collagen type IV and laminin. SlpH inhibited the binding of the enterotoxigenic E. coli by 70 % and 76 % and that of Salmonella Typhimurium SL1344 by 71 % and 75 % to enteric Caco-2 cell line in the exclusion and competition assays, respectively. The pathogen exclusion and competition activity and tolerance to harsh gastrointestinal conditions show the potential for developing SlpH as a prophylactic or therapeutic agent against enteric pathogens.
    Keywords Lactobacillus helveticus ; Salmonella Typhimurium ; bacterial adhesion ; circular dichroism spectroscopy ; collagen ; enterotoxigenic Escherichia coli ; fibronectins ; host-pathogen relationships ; human cell lines ; humans ; intestines ; laminin ; molecular weight ; mucins ; pH ; pathogens ; probiotics ; swine ; therapeutics ; Surface-layer protein ; Probiotic surface adhesins ; Host-microbe interactions ; Circular dichroism ; Pathogen exclusion and competition ; Extracellular surface matrix proteins
    Language English
    Dates of publication 2023-07
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.125146
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Dog tick (Rhipecephalus) causing Lyme disease in an adult human.

    Grover, Ashok Kumar / Singh, Purneetha / Puri, Saurabh / Jindal, Saurabh / Choudhary, Pankaj Nand

    Journal of family medicine and primary care

    2022  Volume 11, Issue 8, Page(s) 4824–4826

    Abstract: Lyme disease is a tick-borne multisystem disorder transmitted by the family of Ixodes and caused by a spirochete, ...

    Abstract Lyme disease is a tick-borne multisystem disorder transmitted by the family of Ixodes and caused by a spirochete,
    Language English
    Publishing date 2022-08-30
    Publishing country India
    Document type Case Reports
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_33_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Bis(thiophen-2-yl-methylene) Benzene-1, 4-Diamine as Fluorescent Probe for the Detection of Fe

    Berhanu, Asnake Lealem / Bhogal, Shikha / Mohiuddin, Irshad / Grover, Aman / Malik, Ashok Kumar / Aulakh, Jatinder Singh

    Journal of fluorescence

    2022  Volume 32, Issue 3, Page(s) 1247–1259

    Abstract: A Schiff base bis(thiophen-2-yl-methylene)benzene-1, 4-diamine (L) was synthesized and used for selective and sensitive detection of ... ...

    Abstract A Schiff base bis(thiophen-2-yl-methylene)benzene-1, 4-diamine (L) was synthesized and used for selective and sensitive detection of Fe
    MeSH term(s) Benzene ; Diamines ; Fluorescent Dyes/chemistry ; Spectrometry, Fluorescence ; Thiophenes ; Water/chemistry
    Chemical Substances Diamines ; Fluorescent Dyes ; Thiophenes ; Water (059QF0KO0R) ; Benzene (J64922108F)
    Language English
    Publishing date 2022-03-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2016892-5
    ISSN 1573-4994 ; 1053-0509
    ISSN (online) 1573-4994
    ISSN 1053-0509
    DOI 10.1007/s10895-022-02914-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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