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  1. Article: Treatment of fungal infection on left ventricle assist device driveline exit site: a case report and systematic review.

    Brandão, Sara Michelly Gonçalves / Biseli, Bruno / Ayub-Ferreira, Silvia Moreira / Strabelli, Tânia Mara Varejão / Bocchi, Edimar Alcides

    Journal of wound care

    2023  Volume 32, Issue Sup9a, Page(s) cxc–cxciv

    Abstract: Objective: The use of ventricular assist devices (VAD) is increasing; however, diagnosis and management of device complications, such as the driveline exit site (DES) being the portal of entry for fungal infection, is not well known.: Method: A ... ...

    Abstract Objective: The use of ventricular assist devices (VAD) is increasing; however, diagnosis and management of device complications, such as the driveline exit site (DES) being the portal of entry for fungal infection, is not well known.
    Method: A systematic review involving searching PubMed (2005 to July 2020) was conducted. The case of a 43-year-old female patient who had a left VAD (LVAD) (HeartMate 3, Abbott, US) is also reported.
    Results: The patient was successfully treated with ketoconazole cream and oral fluconazole for likely superficial DES fungal infections. We included 36 studies that met our inclusion criteria; however, only one was included in our review. In the literature, five cases of DES fungal infection were reported, with
    Conclusion: LVAD fungal infections are uncommon but can be responsible for high mortality rates, require a prolonged period of treatment, and can present a huge problem when surgical alternatives are not available. However,
    MeSH term(s) Female ; Humans ; Adult ; Heart-Assist Devices/adverse effects ; Dermatomycoses ; Candida ; Emollients ; Patient Discharge
    Chemical Substances Emollients
    Language English
    Publishing date 2023-09-13
    Publishing country England
    Document type Case Reports ; Systematic Review ; Journal Article
    ZDB-ID 1353951-6
    ISSN 0969-0700
    ISSN 0969-0700
    DOI 10.12968/jowc.2023.32.Sup9a.cxc
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4572: Show issues Location:
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  2. Article ; Online: Risk Factors for Surgical Site Infection in Patients Undergoing Pediatric Cardiac Surgery.

    Ribeiro, Anna Christina de Lima / Siciliano, Rinaldo Focaccia / Lopes, Antonio Augusto / Strabelli, Tania Mara Varejão

    Arquivos brasileiros de cardiologia

    2023  Volume 120, Issue 12, Page(s) e20220592

    Abstract: Background: Central Illustration : Risk Factors for Surgical Site Infection in Patients Undergoing Pediatric Cardiac Surgery Risk factors for surgical site infection in patients undergoing pediatric cardiac surgery.: Background: Surgical site ... ...

    Title translation Fatores de Risco para Infecção da Ferida Operatória em Pacientes Submetidos à Cirurgia Cardíaca Pediátrica.
    Abstract Background: Central Illustration : Risk Factors for Surgical Site Infection in Patients Undergoing Pediatric Cardiac Surgery Risk factors for surgical site infection in patients undergoing pediatric cardiac surgery.
    Background: Surgical site infection is an important complication after pediatric cardiac surgery, associated with increased morbidity and mortality.
    Objectives: We sought to identify risk factors for surgical site infection after pediatric cardiac surgeries.
    Methods: A case-control study included patients aged between 1 year and 19 years and 11 months of age, submitted to cardiac surgery performed at a tertiary cardiac center from January 1 st , 2011, through December 31, 2018. Charts were reviewed for pre-, intra, and postoperative variables. We identified two randomly selected control patients with the same pathophysiological diagnosis and underwent surgery within thirty days of each index case. Univariate and multivariate logistic regression analyses were performed to identify risk factors. Statistical significance was defined as p<0.05.
    Results: Sixty-six cases and 123 controls were included. Surgical site infection incidence ranged from 2% to 3.8%. The following risk factors were identified: Infant age (OR 3.19, 95% CI 1.26 to 8.66, p=0.014), presence of genetic syndrome (OR 6.20, CI 95% 1.70 to 21.65, p=0.004), categories 3 and 4 of RACHS-1 (OR 8.40, CI 95% 3.30 to 21.34, p<0.001), 48 h C-reactive protein level range was detected as a protective factor for this infection (OR 0.85, 95% CI 0.73 to 0.98, p=0.023).
    Conclusions: The risk factors defined in this study could not be modified. Therefore, additional surveillance and new preventive strategies need to be implemented to reduce the incidence of surgical site infection. The increased CRP in the postoperative period was a protective factor that needs further understanding.
    MeSH term(s) Infant ; Humans ; Child ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology ; Surgical Wound Infection/prevention & control ; Case-Control Studies ; Cardiac Surgical Procedures/adverse effects ; Risk Factors ; Retrospective Studies
    Language English
    Publishing date 2023-12-21
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20220592
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 548: Show issues Location:
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  3. Book ; Online: COVID-19 e o Coração

    Strabelli, Tânia Mara Varejão / Uip, David Everson

    Arquivos Brasileiros de Cardiologia n.ahead 2020

    2020  

    Keywords Coronavirus-19/complicações ; betaCoV/bat/Yunnan/complications ; Febre ; Síndrome Respiratória Aguda Grave ; Dispneia ; Transtornos Respiratórios ; Fatores de Risco ; Hipertensão ; Diabetes Mellitus ; covid19
    Language Portuguese
    Publishing date 2020-01-01
    Publisher Sociedade Brasileira de Cardiologia - SBC
    Publishing country br
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online: COVID-19 e o Coração

    Strabelli, Tânia Mara Varejão / Uip, David Everson

    Arquivos Brasileiros de Cardiologia v.114 n.4 2020

    2020  

    Keywords Coronavirus-19/complicações ; betaCoV/bat/Yunnan/complications ; Febre ; Síndrome Respiratória Aguda Grave ; Dispneia ; Transtornos Respiratórios ; Fatores de Risco ; Hipertensão ; Diabetes Mellitus ; covid19
    Language Portuguese
    Publishing date 2020-04-01
    Publisher Sociedade Brasileira de Cardiologia - SBC
    Publishing country br
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: COVID-19 and the Heart.

    Strabelli, Tânia Mara Varejão / Uip, David Everson

    Arquivos brasileiros de cardiologia

    2020  Volume 114, Issue 4, Page(s) 598–600

    Title translation COVID-19 e o Coração.
    MeSH term(s) Angiotensin-Converting Enzyme 2 ; Betacoronavirus ; COVID-19 ; Cardiovascular Diseases/etiology ; Coronavirus Infections/complications ; Humans ; Pandemics ; Peptidyl-Dipeptidase A/analysis ; Pneumonia, Viral/complications ; SARS-CoV-2
    Chemical Substances Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language Portuguese
    Publishing date 2020-03-30
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20200209
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    Zs.A 548: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Case 4/2019 - 26-Year-Old Man with Congenital Chagas Disease and Heart Transplantation.

    Pinesi, Henrique Trombini / Strabelli, Tânia Mara Varejão / Aiello, Vera Demarchi

    Arquivos brasileiros de cardiologia

    2019  Volume 113, Issue 2, Page(s) 286–293

    MeSH term(s) Adult ; Biopsy ; Chagas Cardiomyopathy/congenital ; Chagas Cardiomyopathy/diagnostic imaging ; Chagas Cardiomyopathy/pathology ; Chagas Cardiomyopathy/surgery ; Electrocardiography ; Heart Transplantation ; Humans ; Magnetic Resonance Imaging ; Male ; Radiography, Thoracic ; Recurrence ; Trypanosoma cruzi/isolation & purification
    Language Portuguese
    Publishing date 2019-09-02
    Publishing country Brazil
    Document type Case Reports ; Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.5935/abc.20190162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  8. Article ; Online: The Predictive Value of Sepsis Scores for In-Hospital Mortality in Patients with Left-Sided Infective Endocarditis.

    Almeida, Bianca Leal de / Strabelli, Tania Mara Varejao / Bittencourt, Marcio Sommer / Oliveira, Vítor Falcão de / Gualandro, Danielle Menosi / Mansur, Alfredo Jose / Tarasouchi, Flavio / Pocebon, Lucas / Paixão, Milena / Goldemberg, Flora / Salomão, Reinaldo / Siciliano, Rinaldo Focaccia

    Tropical medicine and infectious disease

    2024  Volume 9, Issue 1

    Abstract: Background: As infective endocarditis has particular characteristics compared to other infectious diseases, it is not clear if sepsis scores are reported with good accuracy in these patients. The aim of this study is to evaluate the accuracy of the ... ...

    Abstract Background: As infective endocarditis has particular characteristics compared to other infectious diseases, it is not clear if sepsis scores are reported with good accuracy in these patients. The aim of this study is to evaluate the accuracy of the qSOFA and SOFA scores to predict mortality in patients with infective endocarditis.
    Methods: Between January 2010 and June 2019, 867 patients with suspected left-sided endocarditis were evaluated; 517 were included with left-sided infective endocarditis defined as "possible" or "definite" endocarditis, according to the Modified Duke Criteria. ROC curves were constructed to assess the accuracy of qSOFA and SOFA sepsis scores for the prediction of in-hospital mortality.
    Results: The median age was 57 years, 65% were male, 435 (84%) had pre-existing heart valve disease, and the overall mortality was 28%. The most frequent etiologies were
    Conclusions: qSOFA and SOFA scores were associated with increased in-hospital mortality in patients with infective endocarditis. However, as accuracy was relatively lower compared to other sites of bacterial infections, we believe that this score may have lower accuracy when predicting the prognosis of patients with IE, because, in this disease, the patient's death may be more frequently linked to valvular and cardiac dysfunction, as well as embolic events, and less frequently directly associated with sepsis.
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed9010023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Changing trends in clinical characteristics and in-hospital mortality of patients with infective endocarditis over four decades.

    Santos, Diego Augusto Medeiros / Siciliano, Rinaldo Focaccia / Besen, Bruno Adler Maccagnan Pinheiro / Strabelli, Tania Mara Varejão / Sambo, Caio Trevelin / Milczwski, Vitor de Medeiros / Goldemberg, Flora / Tarasoutchi, Flavio / Vieira, Marcelo Luiz Campos / Paixão, Milena Ribeiro / Gualandro, Danielle Menosi / Accorsi, Tarso Augusto Duenhas / Pomerantzeff, Pablo Maria Alberto / Mansur, Alfredo José

    Journal of infection and public health

    2024  Volume 17, Issue 4, Page(s) 712–718

    Abstract: Background: Infective endocarditis continues to be a significant concern and may be undergoing an epidemiological transition.: Methods: Were studied 1804 consecutive episodes of infective endocarditis between 1978 and 2022. The mean age was 48 ( ± 19) ...

    Abstract Background: Infective endocarditis continues to be a significant concern and may be undergoing an epidemiological transition.
    Methods: Were studied 1804 consecutive episodes of infective endocarditis between 1978 and 2022. The mean age was 48 ( ± 19), and 1162 (64%) patients were male. Temporal trends in demographic data, comorbidities, predisposing conditions, microorganisms, complications and in-hospital death have been studied over the decades (1978-1988, 1989-1999, 2000-2010 and 2011-2022). The outcomes and clinical characteristics were modeled using nonlinear cubic spline functions.
    Findings: Valve surgery was performed in 50% of the patients and overall in-hospital mortality was 30%. From the first to the fourth decade studied, the average age of patients increased from 29 to 57 years (p < 0.001), with significant declines in the occurrence of rheumatic valvular heart disease (15% to 6%; p < 0.001) and streptococcal infections (46% to 33%; p < 0.001). Healthcare-associated infections have increased (9% to 21%; p < 0.001), as have prosthetic valve endocarditis (26% to 53%; p < 0.001), coagulase-negative staphylococcal infections (4% to 11%; p < 0.001), and related-complications (heart failure, embolic events, and perivalvular abscess; p < 0.001). These changes were associated with a decline in adjusted in-hospital mortality from 34% to 25% (p = 0.019).
    Interpretation: In the 44 years studied, there was an increase in the mean age of patients, healthcare-related, prosthetic valve, coagulase-negative staphylococci/MRSA infections, and related complications. Notably, these epidemiological changes were associated with a decline in the adjusted in-hospital mortality.
    MeSH term(s) Humans ; Male ; Adult ; Middle Aged ; Female ; Endocarditis, Bacterial/surgery ; Hospital Mortality ; Coagulase ; Heart Valve Prosthesis/adverse effects ; Prosthesis-Related Infections/epidemiology ; Endocarditis/epidemiology ; Staphylococcus ; Staphylococcal Infections/complications
    Chemical Substances Coagulase
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2024.02.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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