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  1. Article: Primary Rhabdomyosarcoma of the Pleura: A Case Report and Review of the Literature.

    Chekhlabi, Nabila / Toughza, Jihane / Dini, Nezha

    Cureus

    2021  Volume 13, Issue 1, Page(s) e12491

    Abstract: Rhabdomyosarcoma is a malignant tumor of striated muscle tissue that can exceptionally present in the pleura. Its prognosis is generally poor. We report a case of an eight-year-old child admitted for a persistent dry cough which had progressed for three ... ...

    Abstract Rhabdomyosarcoma is a malignant tumor of striated muscle tissue that can exceptionally present in the pleura. Its prognosis is generally poor. We report a case of an eight-year-old child admitted for a persistent dry cough which had progressed for three weeks, complicated by breathing difficulties and a deterioration in general condition. He had a history of recent contact with an uncle with pulmonary tuberculosis. Clinical examination on admission revealed right pleural effusion syndrome with moderate respiratory repercussion. The biological assessment shows moderate inflammation and a very high level of lactate dehydrogenase (LDH). Radiologically, there was abundant right pleurisy with intra-pleural nodular masses without ipsilateral pulmonary invasion or other distant localization. Pleural puncture reveals exudative lymphocytic fluid with negative tuberculous polymerase chain reaction (PCR) and atypical cells in cytology. Biopsy of the pleural mass showed pleural rhabdomyosarcoma of the alveolar type. The pet scan found bone metastases at two costal arches. After conditioning, the child received several courses of chemotherapy. The clinical and radiological outcome was favorable. This case is reported in view of its rarity and originality. We conclude that early diagnosis and treatment greatly improves the prognosis of this aggressive tumor.
    Language English
    Publishing date 2021-01-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.12491
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 et greffe de cellules souches hématopoïétiques : recommandations et situation au Maroc.

    Toughza, Jihane / Agadr, Aomar / Ismaili, Nabil

    Bulletin du cancer

    2020  Volume 107, Issue 7-8, Page(s) 741–744

    Title translation COVID-19 and hematopoietic stem cell transplantation: Recommendations.
    MeSH term(s) Aftercare ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Europe ; Hematologic Diseases/therapy ; Hematopoietic Stem Cell Transplantation/methods ; Hematopoietic Stem Cell Transplantation/standards ; Humans ; Hygiene ; Immunotherapy, Adoptive ; Infection Control/methods ; Infection Control/standards ; Morocco/epidemiology ; Neoplasms/therapy ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Practice Guidelines as Topic ; SARS-CoV-2 ; Societies, Medical ; Societies, Scientific ; Tissue Donors ; United States ; World Health Organization
    Keywords covid19
    Language French
    Publishing date 2020-06-20
    Publishing country France
    Document type Letter
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2020.05.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diagnostic et prise en charge d´une thrombopénie néonatale sévère par allo-immunisation materno-fœtale: rapport d´un cas et revue de la littérature.

    Toughza, Jihane / Agadr, Aomar / Nejjari, Mouad / Ammari, Insaf Al

    The Pan African medical journal

    2020  Volume 37, Page(s) 382

    Abstract: Thrombocytopenia is a common hematologic disorder in the neonatal period. It can occur in neonates hospitalized in the Intensive Care Unit and in preterm infants. It is characterized by a platelet count of less than 150.000/ ... ...

    Title translation Diagnosis and management of severe neonatal thrombocytopenia due to maternal alloimmunization against fetal platelet antigens: case study and literature review.
    Abstract Thrombocytopenia is a common hematologic disorder in the neonatal period. It can occur in neonates hospitalized in the Intensive Care Unit and in preterm infants. It is characterized by a platelet count of less than 150.000/mm
    MeSH term(s) Adult ; Antigens, Human Platelet/immunology ; Female ; Fetal Blood/immunology ; Humans ; Immunoglobulin G/immunology ; Infant, Newborn ; Isoantibodies/immunology ; Male ; Pregnancy ; Severity of Illness Index ; Thrombocytopenia, Neonatal Alloimmune/diagnosis ; Thrombocytopenia, Neonatal Alloimmune/immunology
    Chemical Substances Antigens, Human Platelet ; Immunoglobulin G ; Isoantibodies
    Language French
    Publishing date 2020-12-29
    Publishing country Uganda
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2020.37.382.24325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: COVID-19 et greffe de cellules souches hématopoïétiques : recommandations et situation au Maroc./ [COVID-19 and hematopoietic stem cell transplantation: Recommendations]

    Toughza, Jihane / Agadr, Aomar / Ismaili, Nabil

    Bull Cancer

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #633672
    Database COVID19

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  5. Article ; Online: COVID-19 et greffe de cellules souches hématopoïétiques

    Toughza, Jihane / Agadr, Aomar / Ismaili, Nabil

    Bulletin du Cancer

    recommandations et situation au Maroc

    2020  Volume 107, Issue 7-8, Page(s) 741–744

    Keywords Cancer Research ; Oncology ; Radiology Nuclear Medicine and imaging ; Hematology ; General Medicine ; covid19
    Language French
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2020.05.006
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Diagnostic et prise en charge d´une thrombopénie néonatale sévère par allo-immunisation materno-fœtale

    Jihane Toughza / Aomar Agadr / Mouad Nejjari / Insaf Al Ammari

    The Pan African Medical Journal, Vol 37, Iss

    rapport d´un cas et revue de la littérature

    2020  Volume 382

    Abstract: La thrombopénie est une anomalie hématologique fréquente durant la période néonatale particulièrement chez les nouveau-nés hospitalisés en unité de soins intensifs et chez les prématurés. Elle est définie par une numération plaquettaire inférieure à 150 ... ...

    Abstract La thrombopénie est une anomalie hématologique fréquente durant la période néonatale particulièrement chez les nouveau-nés hospitalisés en unité de soins intensifs et chez les prématurés. Elle est définie par une numération plaquettaire inférieure à 150 000/mm3. Parmi les thrombopénies immunes, la thrombopénie par allo-immunisation materno-fœtale d´incidence de 1 cas pour 1 000 naissances, n´est pas un évènement rare mais souvent non diagnostiqué dans les formes mineures. Celle-ci résulte de l´immunisation maternelle contre les antigènes plaquettaires fœtaux hérités du père et absents chez la mère. Les allo anticorps IgG maternels traversent le placenta et provoquent la destruction des plaquettes fœtales. En cas de thrombopénie sévère, les conséquences sont graves avec 10 à 30 % d´hémorragies intracrâniennes. Le diagnostic est essentiellement cli-nique, et doit être connu par les pédiatres.
    Keywords thrombopénie néonatale sévère ; alloimmunisation materno-fœtale ; diagnostic ; prise en charge ; Medicine ; R
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher The Pan African Medical Journal
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Scolarité et devenir social après un cancer dans l'enfance.

    Bonneau, Jacinthe / Dugas, Karyn / Louis, Aurélien / Morel, Laëtitia / Toughza, Jihane / Frappaz, Didier

    Bulletin du cancer

    2015  Volume 102, Issue 7-8, Page(s) 691–697

    Abstract: The survival rate improvement of childhood cancer survivors lead to question about their educational and social outcome. Authors suggest an international review in order to find risk factors of school or social failure after cancer experience. Principal ... ...

    Title translation Educational and social outcome after childhood cancer.
    Abstract The survival rate improvement of childhood cancer survivors lead to question about their educational and social outcome. Authors suggest an international review in order to find risk factors of school or social failure after cancer experience. Principal cohort is studied in USA (the Children Cancer Survivor Study). Nevertheless, European studies are also published. The results vary, depending on subpopulation studied and on control choice (siblings or general population). Treatment improvement and supportive care make difficult to compare studies with current situations. Moreover, there are not international standard of education or social outcome. School and social behaviour are influenced by: types of tumor (cerebral tumor but also sometimes hemopathy and osteosarcoma), age at diagnosis (very young children and adolescent), treatments (neurotoxical treatments, hematopoietic stem cell transplant), and social or educational status of the parents.
    MeSH term(s) Achievement ; Adolescent ; Age Factors ; Bone Neoplasms/therapy ; Brain Neoplasms/therapy ; Child ; Educational Status ; Europe ; Hematologic Neoplasms/therapy ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Osteosarcoma/therapy ; Quality of Life ; Social Skills ; Survivors
    Language French
    Publishing date 2015-07
    Publishing country France
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2015.03.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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