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  1. Article ; Online: Recognizing the complexities of co-prescriptions and life-style factors in opioid agonist treatment: A response from Eleni Domzaridou, Matthew J. Carr, Tim Millar, Roger T. Webb and Darren M. Ashcroft.

    Domzaridou, Eleni / Carr, Matthew J / Millar, Tim / Webb, Roger T / Ashcroft, Darren M

    Addiction (Abingdon, England)

    2024  Volume 119, Issue 5, Page(s) 967–968

    MeSH term(s) Humans ; Analgesics, Opioid/therapeutic use ; Prescriptions ; Drug Overdose/drug therapy ; Benzodiazepines ; Retrospective Studies
    Chemical Substances Analgesics, Opioid ; Benzodiazepines (12794-10-4)
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Letter
    ZDB-ID 1141051-6
    ISSN 1360-0443 ; 0965-2140
    ISSN (online) 1360-0443
    ISSN 0965-2140
    DOI 10.1111/add.16447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Identifying and resolving root causes of poor performance in nitric acid plants

    Ashcroft, Julie

    paper presented to the International Fertiliser Society as part of an open webinar on 19th October 2021

    (Proceedings / International Fertiliser Society ; 860)

    2021  

    Author's details by Julie Ashcroft
    Series title Proceedings / International Fertiliser Society ; 860
    Proceedings / the International Fertiliser Society
    Collection Proceedings / the International Fertiliser Society
    Language English
    Size 16 Seiten, Illustrationen, Diagramme
    Publisher International Fertiliser Society
    Publishing place Colchester
    Publishing country Great Britain
    Document type Book
    Note Literaturverzeichnis: Seite 14-15
    HBZ-ID HT021213809
    ISBN 978-0-85310-497-1 ; 0-85310-497-2
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  3. Article ; Online: A review of the principles and biotechnological applications of glycoside hydrolases from extreme environments.

    Ashcroft, Ellie / Munoz-Munoz, Jose

    International journal of biological macromolecules

    2024  Volume 259, Issue Pt 1, Page(s) 129227

    Abstract: It is apparent that Biocatalysts are shaping the future by providing a more sustainable approach to established chemical processes. Industrial processes rely heavily on the use of toxic compounds and high energy or pH reactions, factors that both ... ...

    Abstract It is apparent that Biocatalysts are shaping the future by providing a more sustainable approach to established chemical processes. Industrial processes rely heavily on the use of toxic compounds and high energy or pH reactions, factors that both contributes to the worsening climate crisis. Enzymes found in bacterial systems and other microorganisms, from the glaciers of the Arctic to the sandy deserts of Abu Dhabi, provide key tools and understanding as to how we can progress in the biotechnology sector. These extremophilic bacteria harness the adaptive enzymes capable of withstanding harsh reaction conditions in terms of stability and reactivity. Carbohydrate-active enzymes, including glycoside hydrolases or carbohydrate esterases, are extremely beneficial for the presence and future of biocatalysis. Their involvement in the industry spans from laundry detergents to paper and pulp treatment by degrading oligo/polysaccharides into their monomeric products in almost all detrimental environments. This includes exceedingly high temperatures, pHs or even in the absence of water. In this review, we discuss the structure and function of different glycoside hydrolases from extremophiles, and how they can be applied to industrial-scale reactions to replace the use of harsh chemicals, reduce waste, or decrease energy consumption.
    MeSH term(s) Glycoside Hydrolases ; Bacteria/chemistry ; Biotechnology ; Extreme Environments ; Extremophiles ; Carbohydrates
    Chemical Substances Glycoside Hydrolases (EC 3.2.1.-) ; Carbohydrates
    Language English
    Publishing date 2024-01-05
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.129227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Exploring educational models within the operating room.

    Ashcroft, James

    Postgraduate medical journal

    2021  Volume 97, Issue 1152, Page(s) 616–619

    MeSH term(s) Clinical Competence ; Humans ; Models, Educational ; Operating Rooms ; Students, Medical
    Language English
    Publishing date 2021-03-10
    Publishing country England
    Document type Editorial
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1136/postgradmedj-2021-139815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Keep older healthcare workers off the covid-19 front line.

    Ashcroft, John

    BMJ (Clinical research ed.)

    2020  Volume 369, Page(s) m1511

    MeSH term(s) Age Factors ; Aged ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Health Personnel ; Health Policy ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Risk Factors ; SARS-CoV-2 ; State Medicine ; United Kingdom
    Keywords covid19
    Language English
    Publishing date 2020-04-17
    Publishing country England
    Document type Letter
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m1511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effective notification systems should be streamlined for the pandemic, not discarded.

    Ashcroft, John

    BMJ (Clinical research ed.)

    2020  Volume 370, Page(s) m3055

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Disease Outbreaks ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-06
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m3055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Strategies for giving feedback in the operating room.

    Marton, Akos / Ashcroft, James

    Postgraduate medical journal

    2023  Volume 99, Issue 1169, Page(s) 211–213

    Abstract: Feedback is crucial to learning and is a difficult concept to define, occurring as a consequence of learner performance with the ultimate aim of influencing change in the learner. Here, we discuss strategies for giving feedback in the operating room ... ...

    Abstract Feedback is crucial to learning and is a difficult concept to define, occurring as a consequence of learner performance with the ultimate aim of influencing change in the learner. Here, we discuss strategies for giving feedback in the operating room revolving around the following themes: encouraging a sociocultural process, forming an educational alliance, sharing training goals, finding the appropriate time, giving task-specific feedback, approaching unsatisfactory performance and providing follow-up. It is essential that surgeons understand the fundamental feedback theories at play in the operating room described in this article and how they influence surgical training at all stages.
    MeSH term(s) Humans ; Feedback ; Operating Rooms ; Learning ; Educational Status ; Surgeons
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1136/postgradmedj-2021-141268
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: First experience in laparoscopic surgery in low and middle income countries: A systematic review.

    Troller, Rebekka / Bawa, Jasmine / Baker, Olivia / Ashcroft, James

    World journal of gastrointestinal surgery

    2024  Volume 16, Issue 2, Page(s) 546–553

    Abstract: Background: Laparoscopic surgery has reduced morbidity and mortality rates, shorter postoperative recovery periods and lower complication rates than open surgery. It is routine practice in high-income countries and is becoming increasingly common in ... ...

    Abstract Background: Laparoscopic surgery has reduced morbidity and mortality rates, shorter postoperative recovery periods and lower complication rates than open surgery. It is routine practice in high-income countries and is becoming increasingly common in countries with limited resources. However, introducing laparoscopic surgery in low-and-middle-income countries (LMIC) can be expensive and requires resources, equipment, and trainers.
    Aim: To report the challenges and benefits of introducing laparoscopic surgery in LMIC as well as to identify solutions to these challenges for countries with limited finances and resources.
    Methods: MEDLINE, EMBASE and Cochrane databases were searched for studies reporting first experience in laparoscopic surgery in LMIC. Included studies were published between 1996 and 2022 with full text available in English. Exclusion criteria were studies considering only open surgery, ear, nose, and throat, endoscopy, arthroscopy, hysteroscopy, cystoscopy, transplant, or bariatric surgery.
    Results: Ten studies out of 3409 screened papers, from eight LMIC were eligible for inclusion in the final analysis, totaling 2497 patients. Most reported challenges were related to costs of equipment and training programmes, equipment problems such as faulty equipment, and access to surgical kits. Training-related challenges were reliance on foreign trainers and lack of locally trained surgeons and theatre staff. The benefits of introducing laparoscopic surgery were economic and clinical, including a reduction in hospital stay, complications, and morbidity/mortality. The introduction of laparoscopic surgery also provided training opportunities for junior doctors.
    Conclusion: Despite financial and technical challenges, many studies emphasise the overall benefit of introducing laparoscopic surgery in LMICs such as reduced hospital stay and the related lower cost for patients. While many of the clinical centres in LMICs have proposed practical solutions to the challenges reported, more support is critically required, in particular regarding training.
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2573700-4
    ISSN 1948-9366
    ISSN 1948-9366
    DOI 10.4240/wjgs.v16.i2.546
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Understanding students' attitudes about work requirements before and during Covid-19.

    Dominic, Catherine / Ashcroft, James / Byrne, Matthew H V

    Medical education

    2024  

    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Letter
    ZDB-ID 195274-2
    ISSN 1365-2923 ; 0308-0110
    ISSN (online) 1365-2923
    ISSN 0308-0110
    DOI 10.1111/medu.15366
    Database MEDical Literature Analysis and Retrieval System OnLINE

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