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  1. Article ; Online: The authors reply.

    Sankar, Jhuma / Das, Rashmi Ranjan

    Critical care medicine

    2024  Volume 52, Issue 5, Page(s) e246–e247

    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000006228
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    Zs.A 1261: Show issues Location:
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  2. Article: Editorial: Insights and advances in pediatric critical care.

    Sankar, Jhuma / Kissoon, Niranjan

    Frontiers in pediatrics

    2022  Volume 10, Page(s) 1057991

    Language English
    Publishing date 2022-10-31
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.1057991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Extracellular Histones-Friend or Foe?

    Tayal, Anshula / Sankar, Jhuma

    Indian journal of pediatrics

    2022  Volume 89, Issue 10, Page(s) 966–967

    MeSH term(s) Histones ; Humans
    Chemical Substances Histones
    Language English
    Publishing date 2022-08-04
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-022-04335-5
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  4. Article ; Online: Advances in Shock Management and Fluid Resuscitation in Children.

    Gupta, Samriti / Sankar, Jhuma

    Indian journal of pediatrics

    2023  Volume 90, Issue 3, Page(s) 280–288

    Abstract: Shock in children is associated with significant mortality and morbidity, particularly in resource-limited settings. The principles of management include early recognition, fluid resuscitation, appropriate inotropes, antibiotic therapy in sepsis, ... ...

    Abstract Shock in children is associated with significant mortality and morbidity, particularly in resource-limited settings. The principles of management include early recognition, fluid resuscitation, appropriate inotropes, antibiotic therapy in sepsis, supportive therapy for organ dysfunction, and regular hemodynamic monitoring. During the past decade, each step has undergone several changes and evolved as evidence that has been translated into recommendations and practice. There is a paradigm shift from protocolized-based care to personalized management, from liberal strategies to restrictive strategies in terms of fluids, blood transfusion, ventilation, and antibiotics, and from clinical monitoring to multimodal monitoring using bedside technologies. However, uncertainties are still prevailing in terms of the volume of fluids, use of steroids, and use of extracorporeal and newer therapies while managing shock. These changes have been summarized along with evidence in this article with the aim of adopting an evidence-based approach while managing children with shock.
    MeSH term(s) Child ; Humans ; Shock, Septic ; Sepsis/drug therapy ; Shock ; Fluid Therapy ; Blood Transfusion ; Anti-Bacterial Agents/therapeutic use ; Resuscitation
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-01-30
    Publishing country India
    Document type Journal Article ; Review ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-022-04434-3
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  5. Article: Sirolimus for multifocal infantile haemangiomas with hepatic & adrenal involvement.

    Sankar, Jhuma / Das, Prasenjit

    The Indian journal of medical research

    2022  Volume 152, Issue Suppl 1, Page(s) S40–S41

    MeSH term(s) Hemangioma/diagnostic imaging ; Hemangioma/drug therapy ; Humans ; Liver Neoplasms/drug therapy ; Sirolimus/therapeutic use
    Chemical Substances Sirolimus (W36ZG6FT64)
    Language English
    Publishing date 2022-03-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_1671_19
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  6. Article ; Online: Impact of 'The Intensivist' in the PICU.

    Parihaar, Man Singh / Sankar, Jhuma

    Indian journal of pediatrics

    2020  Volume 87, Issue 4, Page(s) 251–252

    MeSH term(s) Child ; Controlled Before-After Studies ; Humans ; Income ; Intensive Care Units, Pediatric ; Leadership ; Length of Stay
    Language English
    Publishing date 2020-02-05
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-020-03218-x
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  7. Article ; Online: Infant Pulmonary Function Tests in Children with Airway Anomalies and Correlation with Bronchoscopy Findings.

    Pathania, Amit / Jat, Kana Ram / Sankar, Jhuma / Lodha, Rakesh / Kabra, Sushil K

    Indian pediatrics

    2024  

    Abstract: Objectives: To evaluate the role infant pulmonary function tests (Tidal Breathing Flow Volume Loops, TBFVL) in children with airway anomalies and to correlate the TBFVL so obtained with bronchoscopy findings.: Methods: In this prospective cohort ... ...

    Abstract Objectives: To evaluate the role infant pulmonary function tests (Tidal Breathing Flow Volume Loops, TBFVL) in children with airway anomalies and to correlate the TBFVL so obtained with bronchoscopy findings.
    Methods: In this prospective cohort study, we enrolled children aged 0-2 years with airway anomalies and performed TBFVL and bronchoscopy. The primary outcome measure was graphic pattern of TBFVL in laryngomalacia. Secondary outcome measures were types of TBFVL results in various airway anomalies and controls.
    Results: Out of 53 children enrolled, 28 (52.3%) had laryngomalacia. Pattern 3 (fluttering of inspiratory limb) was commonest TBFVL pattern in laryngomalacia. Among TBFVL parameters, the ratio of inspiratory time to expiratory time (Ti/Te) and tPTEF/tE was significantly high in children with isolated laryngomalacia compared to controls. At six months of follow-up, TBFVL pattern 1 (normal) became the commonest pattern.
    Conclusion: A particular type of airway anomaly may have a characteristic graphic pattern in TBFVL and TBFVL pattern may indicate improvement in airway anomalies in follow-up.
    Language English
    Publishing date 2024-03-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
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    Zs.A 859: Show issues Location:
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  8. Article: Association of Serum Ferritin Levels with Metabolic Syndrome in India: a Cross-Sectional Study.

    Chand, Meena Ramesh / Agarwal, Nagina / Nishanth, Dev / Jhuma, Sankar

    Maedica

    2021  Volume 16, Issue 1, Page(s) 48–53

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-01-06
    Publishing country Romania
    Document type Editorial
    ZDB-ID 2399972-X
    ISSN 2069-6116 ; 1841-9038
    ISSN (online) 2069-6116
    ISSN 1841-9038
    DOI 10.26574/maedica.2020.16.1.48
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  9. Article ; Online: Sirolimus for multifocal infantile haemangiomas with hepatic & adrenal involvement

    Jhuma Sankar / Prasenjit Das

    Indian Journal of Medical Research, Vol 152, Iss 7, Pp 40-

    2020  Volume 41

    Keywords Medicine ; R
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Pediatric Sepsis Phenotypes and Outcome: 5-Year Retrospective Cohort Study in a Single Center in India (2017-2022).

    Sankar, Jhuma / Agarwal, Sheetal / Goyal, Anshu / Kabra, S K / Lodha, Rakesh

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2024  Volume 25, Issue 4, Page(s) e186–e192

    Abstract: Objectives: To describe mortality associated with different clinical phenotypes of sepsis in children.: Design: Retrospective study.: Setting: PICU of a tertiary care center in India from 2017 to 2022.: Patients: Six hundred twelve children ( ... ...

    Abstract Objectives: To describe mortality associated with different clinical phenotypes of sepsis in children.
    Design: Retrospective study.
    Setting: PICU of a tertiary care center in India from 2017 to 2022.
    Patients: Six hundred twelve children (from 2 mo to 17 yr old) with a retrospectively applied diagnosis of sepsis using 2020 guidance.
    Methods: The main outcome was mortality associated with sepsis subtypes. Other analyses included assessment of risk factors, requirement for organ support, and PICU resources used by sepsis phenotype. Clinical data were recorded on a predesigned proforma.
    Interventions: None.
    Measurements and results: Of the 612 children identified, there were 382 (62%) with sepsis but no multiple organ failure (NoMOF), 48 (8%) with thrombocytopenia-associated MOF (TAMOF), 140 (23%) with MOF without thrombocytopenia, and 40 (6.5%) with sequential MOF (SMOF). Mortality was higher in the SMOF (20/40 [50%]), MOF (62/140 [44%]) and TAMOF (20/48 [42%]) groups, compared with NoMOF group (82/382 [21%] [ p < 0.001]). The requirement for organ support and PICU resources was higher in all phenotypes with MOF as compared with those without MOF. On multivariable analysis elevated lactate and having MOF were associated with greater odds of mortality.
    Conclusions: In this single-center experience of sepsis in India, we found that sepsis phenotypes having MOF were associated with mortality and the requirement of PICU resources. Prospective studies in different regions of the world will help identify a classification of pediatric sepsis that is more widely applicable.
    MeSH term(s) Child ; Humans ; Infant ; Retrospective Studies ; Prospective Studies ; Sepsis/diagnosis ; Phenotype ; Thrombocytopenia/epidemiology ; Thrombocytopenia/complications ; Intensive Care Units, Pediatric ; India/epidemiology
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000003449
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