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  1. Book: Mechanical Properties of Human Tissues

    Singh, Gurpreet / Chanda, Arnab

    (Materials Horizons: From Nature to Nanomaterials)

    2023  

    Author's details Dr. Arnab Chanda is an Assistant Professor in the Centre for Biomedical Engineering, Indian Institute of Technology (IIT) Delhi, India and a joint faculty at the Department of Biomedical Engineering, All India Institute of Medical Sciences (AIIMS) Delhi, India. He is also the founder of a startup company BIOFIT Technologies LLC, USA. Dr. Chanda is an expert in the fabrication and mechanical characterization of tissue mimics, and has previously developed artificial surrogates for human skin, muscles, brain, artery, and plantar fascia, and tested them at both lab and clinical settings. These experimental models have been used extensively for surgical training and to study a wide range of injury scenarios. To date, he has received young researcher awards from ASME and MHRD, holds 7 US patents, 2 Indian patents, has authored over 50 articles in reputed international journals. Currently, Dr. Chanda heads the "Disease and Injury Mechanics Lab (DIML)", where his team is working on developi
    Series title Materials Horizons: From Nature to Nanomaterials
    Keywords Soft Tissue ; biomechanics ; Healthcare ; Hyperelastic ; Tissue Simulants ; Medical Models ; Biomechanics
    Language English
    Size 104 p.
    Edition 1
    Publisher Springer Nature Singapore
    Document type Book
    Note PDA Manuell_23
    Format 160 x 241 x 12
    ISBN 9789819922246 ; 9819922240
    Database PDA

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  2. Article ; Online: COVID-19 in India: transmission dynamics, epidemiological characteristics, testing, recovery and effect of weather - Corrigendum.

    Chanda, Arnab

    Epidemiology and infection

    2020  Volume 148, Page(s) e243

    Keywords covid19
    Language English
    Publishing date 2020-10-23
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268820002411
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  3. Article ; Online: COVID-19 in India: transmission dynamics, epidemiological characteristics, testing, recovery and effect of weather.

    Chanda, Arnab

    Epidemiology and infection

    2020  Volume 148, Page(s) e182

    Abstract: The spread of COVID-19 is recent in India, which has within 4 months caused over 190 000 infections, as of 1 June 2020, despite four stringent lockdowns. With the current rate of the disease transmission in India, which is home to over 1.35 billion ... ...

    Abstract The spread of COVID-19 is recent in India, which has within 4 months caused over 190 000 infections, as of 1 June 2020, despite four stringent lockdowns. With the current rate of the disease transmission in India, which is home to over 1.35 billion people, the infection spread is predicted to be worse than the USA in the upcoming months. To date, there is a major lack of understanding of the transmission dynamics and epidemiological characteristics of the disease in India, inhibiting effective measures to control the pandemic. We collected all the available data of the individual patients, cases and a range of parameters such as population distribution, testing and healthcare facilities, and weather, across all Indian states till May 2020. Numerical analysis was conducted to determine the effect of each parameter on the COVID-19 situation in India. A significant amount of local transmission in India initiated with travellers returning from abroad. Maharashtra, Tamil Nadu and Delhi are currently the top three infected states in India with doubling time of 14.5 days. The average recovery rate across Indian states is 42%, with a mortality rate below 3%. The rest 55% are currently active cases. In total, 88% of the patients experienced symptoms of high fever, 68% suffered from dry cough and 7.1% patients were asymptomatic. In total, 66.8% patients were males, 73% were in the age group of 20-59 years and over 83% recovered in 11-25 days. Approximately 3.4 million people were tested between 1 April and 25 May 2020, out of which 4% were detected COVID-19-positive. Given the current doubling time of infections, several states may face a major shortage of public beds and healthcare facilities soon. Weather has minimal effect on the infection spread in most Indian states. The study results will help policymakers to predict the trends of the disease spread in the upcoming months and devise better control measures.
    MeSH term(s) Adult ; Betacoronavirus/physiology ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Communicable Disease Control ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/mortality ; Coronavirus Infections/transmission ; Female ; Health Resources ; Humans ; India/epidemiology ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/transmission ; Population Density ; SARS-CoV-2 ; Travel ; Weather
    Keywords covid19
    Language English
    Publishing date 2020-08-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268820001776
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  4. Article ; Online: Biomechanical modeling of footwear-fluid-floor interaction during slips.

    Gupta, Shubham / Chanda, Arnab

    Journal of biomechanics

    2023  Volume 156, Page(s) 111690

    Abstract: Slips and falls are among the major concerns for public safety. Slipping risks can be reduced by ensuring adequate traction at the shoe-floor interface. The outsole design of footwear is a critical factor to maintain sufficient shoe-floor traction in the ...

    Abstract Slips and falls are among the major concerns for public safety. Slipping risks can be reduced by ensuring adequate traction at the shoe-floor interface. The outsole design of footwear is a critical factor to maintain sufficient shoe-floor traction in the presence of slippery contaminants such as water or oil. While the role of floorings and contaminants on footwear traction has been studied widely, limited works have investigated the role of footwear outsole geometry and tread patterns on shoe-floor traction. In this work, eight footwear outsole designs and their traction performance were tested on a common flooring with water contamination, through the development of a novel fluid-structure interaction based computational framework. Induced fluid pressure, mass flow rates, and contact areas were quantified across the outsole patterns, and their effect on footwear friction was investigated. The study results were validated using mechanical slip testing experiments. The results indicated that the outsoles which had horizontal treads or untreaded heel regions can lead to drastic reduction of footwear friction. Also, contact area alone was quantified to be a poor choice in estimating the traction performance of footwear on water contaminated floorings. Such novel study results have not been reported to date, and are anticipated to provide important guidelines to footwear manufacturers to evaluate and optimize footwear tread parameters which would help in reducing the risk of slips.
    MeSH term(s) Friction ; Floors and Floorcoverings ; Shoes ; Accidental Falls/prevention & control ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218076-5
    ISSN 1873-2380 ; 0021-9290
    ISSN (online) 1873-2380
    ISSN 0021-9290
    DOI 10.1016/j.jbiomech.2023.111690
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  6. Article ; Online: COVID-19 in India

    Chanda, Arnab

    Epidemiology and Infection

    transmission dynamics, epidemiological characteristics, testing, recovery and effect of weather – Corrigendum

    2020  Volume 148

    Keywords Epidemiology ; Infectious Diseases ; covid19
    Language English
    Publisher Cambridge University Press (CUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/s0950268820002411
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  7. Article ; Online: Development of patient-specific finite element model for study of composite dental implants.

    Gupta, Vivek / Garg, Anshika / Tewari, Nitesh / Srivastav, Sukeshana / Chanda, Arnab

    Biomedical physics & engineering express

    2024  Volume 10, Issue 2

    Abstract: Traumatic dental injuries can occur due to various reasons such as accidents, sports injuries, fights, falls, and others. These injuries can affect the teeth, gums, and surrounding tissues, and can range from minor chips and cracks to severe fractures, ... ...

    Abstract Traumatic dental injuries can occur due to various reasons such as accidents, sports injuries, fights, falls, and others. These injuries can affect the teeth, gums, and surrounding tissues, and can range from minor chips and cracks to severe fractures, dislocations, and avulsions (when the tooth is completely knocked out of the socket). The most common way to address this is by replacing affected teeth with dental implants. The purpose of this research is to evaluate the use of composite materials in dental implants and compare them with the traditionally used materials using a patient specific cone beam computed tomography (CBCT) based finite element model (FEM). To conduct this research, two different implant groups i.e., traditional implant and composite implant were designed using Titanium grade 4, zirconium oxide-reinforced lithium silicate (ZLS), and Zirconia (ZrO
    MeSH term(s) Humans ; Dental Implants ; Finite Element Analysis ; Software ; Maxilla ; Crowns ; Zirconium
    Chemical Substances Dental Implants ; zirconium oxide (S38N85C5G0) ; Zirconium (C6V6S92N3C)
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ISSN 2057-1976
    ISSN (online) 2057-1976
    DOI 10.1088/2057-1976/ad28ce
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  8. Article: Editorial: Advances and Perspective in bio-implants for commercialization.

    Sidhu, Sarabjeet Singh / Chanda, Arnab / Abdel-Hady Gepreel, Mohamed

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1306077

    Language English
    Publishing date 2023-10-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1306077
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  9. Article ; Online: Biomechanical Modeling of Human Skin Tissue Surrogates.

    Chanda, Arnab

    Biomimetics (Basel, Switzerland)

    2018  Volume 3, Issue 3

    Abstract: Surrogates, which precisely simulate nonlinear mechanical properties of the human skin at different body sites, would be indispensable for biomechanical testing applications, such as estimating the accurate load response of skin implants and prosthetics ... ...

    Abstract Surrogates, which precisely simulate nonlinear mechanical properties of the human skin at different body sites, would be indispensable for biomechanical testing applications, such as estimating the accurate load response of skin implants and prosthetics to study the biomechanics of static and dynamic loading conditions on the skin, dermatological and sports injuries, and estimating the dynamic load response of lethal and nonlethal ballistics. To date, human skin surrogates have been developed mainly with materials, such as gelatin and polydimethylsiloxane (PDMS), based on assumption of simplified mechanical properties, such as an average elastic modulus (estimated through indentation tests), and Poisson's ratio. In addition, pigskin and cowhides, which have widely varying mechanical properties, have been used to simulate human skin. In the current work, a novel elastomer-based material system is developed, which precisely mimics the nonlinear stress-stretch behavior, elastic modulus at high and low strains, and fracture strengths of the natural human skin at different body sites. The manufacturing and fabrication process of these skin surrogates are discussed, and mechanical testing results are presented.
    Language English
    Publishing date 2018-07-23
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2313-7673
    ISSN (online) 2313-7673
    DOI 10.3390/biomimetics3030018
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  10. Article ; Online: Finite element analysis of a hybrid corrugated hip implant for stability and loading during gait phases.

    Gupta, Vivek / Chanda, Arnab

    Biomedical physics & engineering express

    2022  Volume 8, Issue 3

    Abstract: Implants used in total hip replacements (THR) exhibit high failure rates and up to a decade of operational life. These surgical failures could be mainly attributed to the improper positioning, post-surgical stability and loading, of the implants during ... ...

    Abstract Implants used in total hip replacements (THR) exhibit high failure rates and up to a decade of operational life. These surgical failures could be mainly attributed to the improper positioning, post-surgical stability and loading, of the implants during different phases of the gait. Typically, revised surgeries are suggested within a few years of hip implantation, which requires multiple femoral drilling operations to remove an existing implant, and to install a new implant. The pain and trauma associated with such procedures are also challenging with the existing hip implants. In this work, we designed a novel corrugated hip implant with innovative dimensioning as per ASTM standards, and grooves for directed insertion and removal (using a single femoral drilling and positioning operation). Biocompatible titanium alloy (Ti6Al4V) was chosen as the implant material, and the novel implant was placed into a femur model through a virtual surgery to study its stability and loading during a dynamic gait cycle. A detailed mesh convergence study was conducted to select a computationally accurate finite element (FE) mesh. Tight fit and frictional fit attachment conditions were simulated, and the gait induced displacements and stresses on the implant, cortical and cancellous bone sections were characterized. During walking, the implant encountered the maximum von-Mises stress of 254.97 MPa at the femoral head. The analyses indicated low micro-motions (i.e., approximately 7
    MeSH term(s) Arthroplasty, Replacement, Hip ; Finite Element Analysis ; Gait ; Hip Prosthesis ; Stress, Mechanical
    Language English
    Publishing date 2022-04-27
    Publishing country England
    Document type Journal Article
    ISSN 2057-1976
    ISSN (online) 2057-1976
    DOI 10.1088/2057-1976/ac669c
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