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  1. Article ; Online: Reply to: Comments on recent viewpoint article by Lazzaro di Biase and Alfonso Fasano titled "Low-frequency deep brain stimulation for Parkinson's disease: Great expectation or false hope?"

    di Biase, Lazzaro / Fasano, Alfonso

    Movement disorders : official journal of the Movement Disorder Society

    2017  Volume 32, Issue 1, Page(s) 176–177

    MeSH term(s) Deep Brain Stimulation ; Humans ; Parkinson Disease ; Subthalamic Nucleus
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.26859
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    Zs.MO 238: Show issues

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  2. Article ; Online: Dystonia and parkinsonism: Not an easy combo.

    Montiel, Marcela / Fasano, Alfonso

    Parkinsonism & related disorders

    2024  , Page(s) 106009

    Language English
    Publishing date 2024-01-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1311489-x
    ISSN 1873-5126 ; 1353-8020
    ISSN (online) 1873-5126
    ISSN 1353-8020
    DOI 10.1016/j.parkreldis.2024.106009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reply to: Comment on: A Transatlantic Viewpoint on the Role of Pallidal Stimulation for Parkinson's Disease.

    Boogers, Alexandra / Fasano, Alfonso

    Movement disorders : official journal of the Movement Disorder Society

    2024  Volume 39, Issue 4, Page(s) 761

    MeSH term(s) Humans ; Parkinson Disease/therapy ; Deep Brain Stimulation/methods ; Globus Pallidus/physiology
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Letter
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.29780
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  4. Article ; Online: An Apple a Day Will Not Keep the (Parkinson Disease) Doctor at Bay!

    Boogers, Alexandra / Fasano, Alfonso / Lang, Anthony

    Annals of neurology

    2024  

    Language English
    Publishing date 2024-03-30
    Publishing country United States
    Document type Letter
    ZDB-ID 80362-5
    ISSN 1531-8249 ; 0364-5134
    ISSN (online) 1531-8249
    ISSN 0364-5134
    DOI 10.1002/ana.26936
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  5. Book ; Online ; E-Book: Fundamentals and Clinics of Deep Brain Stimulation

    Temel, Yasin / Leentjens, Albert F.G. / de Bie, Rob M.A. / Chabardes, Stephan / Fasano, Alfonso

    An Interdisciplinary Approach

    2020  

    Abstract: This book deals with a rapidly growing field of medical science: deep brain stimulation (DBS). Influencing deep brain networks by electrical stimulation through implanted electrodes is increasingly applied, and DBS has become a popular treatment for ... ...

    Author's details edited by Yasin Temel, Albert F.G. Leentjens, Rob M.A. de Bie, Stephan Chabardes, Alfonso Fasano
    Abstract This book deals with a rapidly growing field of medical science: deep brain stimulation (DBS). Influencing deep brain networks by electrical stimulation through implanted electrodes is increasingly applied, and DBS has become a popular treatment for neurological and psychiatric indications. Professionals in the field of DBS are expected to understand classical subjects as disease mechanisms, brain anatomy and function, and clinical symptomatology of the diseases they treat. In addition, they are required to be familiar with specific patient management skills and treatment strategies. A third dimension is hardware and software-related knowledge. Depending on the degree of involvement, professionals need to understand basic or advanced concepts of stimulation protocols. All these aspects of DBS are discussed in this book. Authors from many different disciplines, from many different countries, have contributed their expertise and personal experience to this book. Their contributions reflect the multidisciplinary nature of DBS treatment. This book is written for a wide readership that involves many different professionals and disciplines, including neurologists, neurosurgeons, psychiatrists, neurophysiologists, neuroanatomists, psychologists, rehabilitation specialists, nurses, speech therapists, physiotherapists, engineers and other paramedical disciplines. In our society, where sharing expertise and experience, and global knowledge has become the new standard, patients want the best possible DBS therapy. One prerequisite for this is the presence of a well-integrated and dedicated multidisciplinary team, with up-to-date knowledge of the possibilities of DBS treatment. .
    Keywords Nervous system/Surgery ; Neurology ; Psychiatry ; Clinical psychology ; Neurosciences ; Nursing ; Neurosurgery ; Clinical Psychology ; Neuroscience
    Subject code 617.48
    Language English
    Size 1 online resource (XII, 307 p. 62 illus., 43 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-36346-5 ; 3-030-36345-7 ; 978-3-030-36346-8 ; 978-3-030-36345-1
    DOI 10.1007/978-3-030-36346-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Book ; Online: Levodopa-induced Dyskinesias in Parkinsons Disease: Current Knowledge and Future Scenarios

    Fasano, Alfonso / Koch, Giacomo / Cerasa, Antonio / Morgante, Francesca

    2015  

    Abstract: This topic aims to pool the most recent advances in the phenomenology and pathophysiology of levodopa-induced dyskinesias. The papers in this eBook have strongly contributed to reduce the gaps in our knowledge of LIDs ... ...

    Abstract This topic aims to pool the most recent advances in the phenomenology and pathophysiology of levodopa-induced dyskinesias. The papers in this eBook have strongly contributed to reduce the gaps in our knowledge of LIDs pathogenesis
    Keywords Neurology. Diseases of the nervous system ; Medicine (General)
    Size 1 electronic resource (99 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020090490
    ISBN 9782889195459 ; 2889195457
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Article ; Online: A Transatlantic Viewpoint on the Role of Pallidal Stimulation for Parkinson's Disease.

    Boogers, Alexandra / Fasano, Alfonso

    Movement disorders : official journal of the Movement Disorder Society

    2023  Volume 39, Issue 1, Page(s) 36–39

    MeSH term(s) Humans ; Parkinson Disease/therapy ; Globus Pallidus/physiology ; Subthalamic Nucleus/physiology ; Deep Brain Stimulation
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.29656
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  8. Article ; Online: Punding in Parkinson's Disease: An Update.

    Rajalingam, Rajasumi / Fasano, Alfonso

    Movement disorders clinical practice

    2023  Volume 10, Issue 7, Page(s) 1035–1047

    Abstract: Background: Punding is a stereotyped behavior characterized by an intense fascination with a complex, excessive, non-goal oriented, repetitive activity affecting individuals with Parkinson's disease (PD) on dopamine replacement therapy (DRT).: ... ...

    Abstract Background: Punding is a stereotyped behavior characterized by an intense fascination with a complex, excessive, non-goal oriented, repetitive activity affecting individuals with Parkinson's disease (PD) on dopamine replacement therapy (DRT).
    Objectives: In 2010, we published the first review focused on the pathophysiology of punding. This study aims to systematically review the literature of the past decade on punding in PD, particularly focusing on the clinical features, underlying pathophysiological mechanisms, and treatment.
    Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we searched PubMed, Embase, and APA PsycInfo for articles published between July 1, 2010 and March 19, 2022. The search strategy included: (punding) AND (parkinson*).
    Results: Of 256 studies identified, 29 were eligible for inclusion with 19 original research articles and 10 case reports. This review confirmed that predictors of punding in PD are higher doses of DRT, younger age, male sex, and increasing disease severity. We also found an association between punding and psychiatric and/or cognitive symptoms. Neuroimaging studies have showed that punding in PD is associated with a disconnection between midbrain, limbic and white matter tracts projecting to the frontal cortices and a breakdown of the connectivity among the crucial nodes of the reward circuit. Low-frequency repetitive transcranial magnetic stimulation on the dorsolateral prefrontal cortex has been shown to produce a transient beneficial effect in PD patients with punding.
    Conclusion: In conclusion, although the clinical features of punding have been established, in the past 12 years, we gained a better understanding of the pathophysiological mechanisms of punding, mainly thanks to magnetic resonance imaging techniques.
    Language English
    Publishing date 2023-04-23
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2330-1619
    ISSN (online) 2330-1619
    DOI 10.1002/mdc3.13748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Another Step Forward for Freezing of Gait in Parkinson's Disease.

    Fomenko, Anton / Fasano, Alfonso / Kalia, Suneil K

    Journal of Parkinson's disease

    2024  Volume 14, Issue 2, Page(s) 353–355

    Abstract: The study "A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease" by Milekovic et al. introduces a novel neuroprosthesis for treating locomotor deficits in late-stage Parkinson's disease (PD). This approach employs an epidural ... ...

    Abstract The study "A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease" by Milekovic et al. introduces a novel neuroprosthesis for treating locomotor deficits in late-stage Parkinson's disease (PD). This approach employs an epidural spinal array targeting dorsal roots and electromyography to create a spatiotemporal map of muscle activation, aiming to restore natural gait patterns. Significant improvements in gait freezing and balance were observed in both non-human primate models and a human patient, resulting in improved mobility and quality of life. This innovative method, integrating real-time feedback and non-invasive motor intention decoding, marks a significant advancement in PD treatment.
    MeSH term(s) Animals ; Humans ; Parkinson Disease/complications ; Parkinson Disease/therapy ; Gait Disorders, Neurologic/etiology ; Gait Disorders, Neurologic/therapy ; Quality of Life ; Gait/physiology ; Spinal Cord
    Language English
    Publishing date 2024-01-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2620609-2
    ISSN 1877-718X ; 1877-7171
    ISSN (online) 1877-718X
    ISSN 1877-7171
    DOI 10.3233/JPD-230412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Healthcare Differences and COVID-19 Impact on Parkinson's Disease.

    Rodríguez-Quiroga, Sergio / Fasano, Alfonso

    Movement disorders clinical practice

    2022  Volume 9, Issue 6, Page(s) 846–849

    Language English
    Publishing date 2022-06-10
    Publishing country United States
    Document type Journal Article
    ISSN 2330-1619
    ISSN (online) 2330-1619
    DOI 10.1002/mdc3.13491
    Database MEDical Literature Analysis and Retrieval System OnLINE

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