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  1. Article: Retraction: Intussusception in Adults: A Rare Etiology of Small Intestinal Obstruction.

    Alshahrani, Abdulwahab A / Alotaibi, Naif A / Alzahrani, Fahad K / Alaqidi, Meshal F / Alabbad, Faisal A / Alqarni, Mohammed A / Altwirki, Abdulah A / Alshabri, Meshari I / Al Dakheel, Khalid A / Faqihi, Essa J / Mijlad, Waleed K / Al-Hawaj, Faisal

    Cureus

    2024  Volume 16, Issue 1, Page(s) r117

    Abstract: This retracts the article DOI: 10.7759/cureus.20502.]. ...

    Abstract [This retracts the article DOI: 10.7759/cureus.20502.].
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Retraction of Publication
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.r117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Therapeutic plasma exchange (removal of the non-cell portion of blood) in critically ill adult patients with serious SARS CoV-2 disease (COVID-19)

    Karakitsos, Dimitrios / Faqihi, Fahad

    http://isrctn.com/

    2020  

    Keywords covid19
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Book ; Online
    DOI 10.1186/isrctn21363594
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Therapeutic plasma exchange in life-threatening COVID-19 and associated cytokine release syndrome.

    Faqihi, Fahad / Alharthy, Abdulrahman / Karakitsos, Dimitrios

    Journal of the Formosan Medical Association = Taiwan yi zhi

    2020  Volume 119, Issue 12, Page(s) 1888–1889

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/therapy ; Cytokine Release Syndrome ; Cytokines ; Humans ; Pandemics ; Plasma Exchange ; Pneumonia, Viral ; SARS-CoV-2
    Chemical Substances Cytokines
    Keywords covid19
    Language English
    Publishing date 2020-07-13
    Publishing country Singapore
    Document type Letter ; Comment
    ZDB-ID 2096659-3
    ISSN 1876-0821 ; 0929-6646
    ISSN (online) 1876-0821
    ISSN 0929-6646
    DOI 10.1016/j.jfma.2020.07.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1041: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: SARS-CoV-2 Complicated by Sinusitis and Co-Infection with Human Metapneumovirus.

    Alharthy, Abdulrahman / Faqihi, Fahad / Karakitsos, Dimitrios

    Rhode Island medical journal (2013)

    2020  Volume 103, Issue 6, Page(s) 23–24

    Abstract: A previously healthy 25-year-old Asian male was admitted with acute respiratory failure due to COVID-19 pneumonia to our intensive care unit. He received empiric therapy and higher level of respiratory support via a high flow nasal cannula. Notably, ... ...

    Abstract A previously healthy 25-year-old Asian male was admitted with acute respiratory failure due to COVID-19 pneumonia to our intensive care unit. He received empiric therapy and higher level of respiratory support via a high flow nasal cannula. Notably, human metapneumovirus was detected from the nasopharyngeal swab by RT-PCR. Six days post-ICU admission, sinusitis was clinically and sonographically detected. SARS-CoV-2 was detected in the fluid aspirated from the antrum. The patient has made an uneventful recovery. Further studies are required to investigate co-infections with SARS-CoV-2 and other viruses.
    MeSH term(s) Adult ; Betacoronavirus/isolation & purification ; COVID-19 ; Coinfection ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Humans ; Intensive Care Units ; Male ; Metapneumovirus/isolation & purification ; Nasopharynx/virology ; Pandemics ; Paramyxoviridae Infections/complications ; Paramyxoviridae Infections/diagnosis ; Paramyxoviridae Infections/therapy ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Sinusitis/diagnostic imaging
    Keywords covid19
    Language English
    Publishing date 2020-08-03
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 419430-5
    ISSN 2327-2228 ; 0363-7913
    ISSN (online) 2327-2228
    ISSN 0363-7913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 222: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Therapeutic plasma exchange in life-threatening COVID-19 and associated cytokine release syndrome

    Fahad Faqihi / Abdulrahman Alharthy / Dimitrios Karakitsos

    Journal of the Formosan Medical Association, Vol 119, Iss 12, Pp 1888-

    2020  Volume 1889

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Comment on Hu et al: The cytokine storm and COVID-19.

    Faqihi, Fahad / Alharthy, Abdulrahman / Memish, Ziad A / Karakitsos, Dimitrios

    Journal of medical virology

    2020  Volume 93, Issue 2, Page(s) 631–633

    MeSH term(s) COVID-19 ; Cytokine Release Syndrome ; Cytokines ; Humans ; SARS-CoV-2
    Chemical Substances Cytokines
    Keywords covid19
    Language English
    Publishing date 2020-08-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26396
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1320: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Managing High Frequency of Ambulance Calls in Hospitals: A Systematic Review.

    Alruwaili, Abdullah / Alanazy, Ahmed / Alanazi, Turki M / Alobaidi, Nowaf / Almamary, Ahmad Saleh / Faqihi, Bandar M / Al Enazi, Fahad H / Siraj, Rayan / Almukhlifi, Yasir / Al Nufaiei, Ziyad F / Alsulami, Maher

    Risk management and healthcare policy

    2024  Volume 17, Page(s) 287–296

    Abstract: Background: This study addresses the critical issue of high-volume emergency calls in hospitals, focusing on the strain caused by frequent caller patients on ambulance services. The aim was to synthesize various management methods for handling high- ... ...

    Abstract Background: This study addresses the critical issue of high-volume emergency calls in hospitals, focusing on the strain caused by frequent caller patients on ambulance services. The aim was to synthesize various management methods for handling high-frequency hospital calls.
    Methods: The systematic review was conducted following the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines and guided by the Cochrane Handbook for systematic reviews. Inclusion criteria encompassed studies focusing on the management of emergency departments in hospitals, exploring various medical conditions requiring ambulance attention, and reporting on the impact of a high volume of ambulance calls on hospitals. Databases including PubMed, Web of Science, and Google Scholar were searched from January 1, 2005, to May 1, 2022. The quality of included studies was assessed using the Critical Appraisal Skills Programme (CASP) Checklist.
    Results: Out of 2390 identified citations, 18 studies met the inclusion criteria. These studies, from 12 countries, presented diverse methods categorized into country policy-based management, modeling approaches, and general strategies. Key findings included the effectiveness of risk stratification models and community-based interventions in managing high call frequencies and improving patient care. Our review identified effective strategies such as risk stratification models and community-based interventions, which have shown significant impacts in managing high call frequencies, aligning closely with our objective. These approaches have been pivotal in reducing the burden on emergency services and improving patient care.
    Conclusion: The study synthesizes effective management methods for high-frequency ambulance calls, including predictive modeling and community interventions. It highlights the need for multi-faceted management strategies in different healthcare settings and underscores the importance of continued research and implementation of these methods to improve emergency service efficiency.
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2495128-6
    ISSN 1179-1594
    ISSN 1179-1594
    DOI 10.2147/RMHP.S436265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Lung Injury in COVID-19-An Emerging Hypothesis.

    Alharthy, Abdulrahman / Faqihi, Fahad / Memish, Ziad A / Karakitsos, Dimitrios

    ACS chemical neuroscience

    2020  Volume 11, Issue 15, Page(s) 2156–2158

    Abstract: Lung injury with COVID-19 may be due to a complex underlying pathophysiology. Cytokine release syndrome appears to be a catalyst of different inflammatory pathways promoting lung parenchymal injury and thromboembolic phenomena ("dual hit" injury). ... ...

    Abstract Lung injury with COVID-19 may be due to a complex underlying pathophysiology. Cytokine release syndrome appears to be a catalyst of different inflammatory pathways promoting lung parenchymal injury and thromboembolic phenomena ("dual hit" injury). Recently, severe neurological manifestations such as acute disseminated encephalomyelitis, which may be not linked to lung pathology, have been identified in COVID-19, contributing thus further to the versatility of its clinical features.
    MeSH term(s) Animals ; Betacoronavirus/metabolism ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/metabolism ; Coronavirus Infections/physiopathology ; Cytokines/metabolism ; Humans ; Lung Injury/etiology ; Lung Injury/metabolism ; Lung Injury/physiopathology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/physiopathology ; SARS-CoV-2
    Chemical Substances Cytokines
    Keywords covid19
    Language English
    Publishing date 2020-07-24
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.0c00422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Molecular docking analysis of KRAS inhibitors for cancer management.

    J Hakeem, Israa / Alsharif, Fatmah Hazza / Aljadani, Majidah / Fahad Alabbas, Ibrahim / Faqihi, Mohammed Saud / Aloufi, Ahmed Hamdan / Almutairi, Wael Abdullah / Akber, Asif Hussain / Alam, Qamre

    Bioinformation

    2023  Volume 19, Issue 4, Page(s) 411–416

    Abstract: The majority of human tumors are characterized by abnormal signaling caused by oncogenic RAS proteins. KRAS is a member of the RAS family and is currently one of the most thoroughly researched targets for cancer treatment due to its prevalence in a ... ...

    Abstract The majority of human tumors are characterized by abnormal signaling caused by oncogenic RAS proteins. KRAS is a member of the RAS family and is currently one of the most thoroughly researched targets for cancer treatment due to its prevalence in a variety of deadly malignancies. Targeting the KRAS protein, which plays a crucial role in regulating cell growth, differentiation, and apoptosis, shows great potential as a strategy for fighting cancer. Herein, in silico screening of 530 natural compounds against KRAS protein was performed. The top-scoring hits, namely ZINC32502206, ZINC98363763, ZINC85645815, and ZINC98364259 displayed a robust affinity towards KRAS as evidenced by their respective binding affinity values of -10.50, -10.01, -9.80, and -9.70 kcal/mol, respectively which were notably higher than that of the control compound AMG 510 (-9.10 kcal/mol). Through virtual screening and visual inspection, it was observed that these hits effectively interacted with the essential residues located within the active site of KRAS. Based on the findings of this study, it can be inferred that these compounds may have the potential to be employed in the treatment of cancer by targeting KRAS.
    Language English
    Publishing date 2023-04-30
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/97320630019411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Fragile Endothelium and Brain Dysregulated Neurochemical Activity in COVID-19.

    Alharthy, Abdulrahman / Faqihi, Fahad / Memish, Ziad A / Karakitsos, Dimitrios

    ACS chemical neuroscience

    2020  Volume 11, Issue 15, Page(s) 2159–2162

    Abstract: Immune system and renin-angiotensin-aldosterone system dysregulation with associated cytokine release syndrome may be a key feature of early stage of SARS-CoV-2 organotropism and infection. Following viral mediated brain injury, dysregulated ... ...

    Abstract Immune system and renin-angiotensin-aldosterone system dysregulation with associated cytokine release syndrome may be a key feature of early stage of SARS-CoV-2 organotropism and infection. Following viral mediated brain injury, dysregulated neurochemical activity may cause neurogenic stress cardiomyopathy, which is characterized by transient myocardial dysfunction and arrhythmias. Cardiomyopathy along with acute acute inflammatory thromboembolism and endotheliitis (fragile endothelium) might at least partially explain the underlying mechanisms of rapidly evolving life-threatening COVID-19. Further studies are clearly required to explore these complex pathologies.
    MeSH term(s) Animals ; Betacoronavirus/metabolism ; Brain/immunology ; Brain/metabolism ; Brain/pathology ; Brain Chemistry/physiology ; COVID-19 ; Coronavirus Infections/immunology ; Coronavirus Infections/metabolism ; Coronavirus Infections/pathology ; Endothelium, Vascular/immunology ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Humans ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/pathology ; Renin-Angiotensin System/physiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-27
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.0c00437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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