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  1. Article ; Online: Establishing an out-of-hospital cardiac arrest registry in China: a key first step to improving outcomes.

    Mellett-Smith, Adam / Couper, Keith

    The Lancet. Public health

    2023  Volume 8, Issue 12, Page(s) e908–e909

    MeSH term(s) Humans ; Out-of-Hospital Cardiac Arrest/epidemiology ; Out-of-Hospital Cardiac Arrest/therapy ; Registries ; Cardiopulmonary Resuscitation ; China/epidemiology
    Language English
    Publishing date 2023-09-16
    Publishing country England
    Document type Journal Article
    ISSN 2468-2667
    ISSN (online) 2468-2667
    DOI 10.1016/S2468-2667(23)00208-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The quality of quality-of-life outcome data: The challenge of data interpretation.

    Couper, Keith

    Resuscitation

    2019  Volume 146, Page(s) 266–267

    MeSH term(s) Heart Arrest ; Humans ; Intensive Care Units ; Prospective Studies ; Quality of Life ; Surveys and Questionnaires
    Language English
    Publishing date 2019-12-09
    Publishing country Ireland
    Document type Editorial ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2019.11.029
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    Zs.A 1048: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Improving vasopressor use in cardiac arrest.

    Perkins, Gavin D / Couper, Keith

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 81

    Abstract: The Chain of Survival highlights the effectiveness of early recognition of cardiac arrest and call for help, early cardiopulmonary resuscitation and early defibrillation. Most patients, however, remain in cardiac arrest despite these interventions. Drug ... ...

    Abstract The Chain of Survival highlights the effectiveness of early recognition of cardiac arrest and call for help, early cardiopulmonary resuscitation and early defibrillation. Most patients, however, remain in cardiac arrest despite these interventions. Drug treatments, particularly the use of vasopressors, have been included in resuscitation algorithms since their inception. This narrative review describes the current evidence base for vasopressors and reports that adrenaline (1 mg) is highly effective at achieving return of spontaneous circulation (number needed to treat 4) but is less effective on long-term outcomes (survival to 30 days, number needed to treat 111) with uncertain effects on survival with a favourable neurological outcome. Randomised trials evaluating vasopressin, either as an alternative to or in addition to adrenaline, and high-dose adrenaline have failed to find evidence of improved long-term outcomes. There is a need for future trials to evaluate the interaction between steroids and vasopressin. Evidence for other vasopressors (e.g. noradrenaline, phenylephedrine) is insufficient to support or refute their use. The use of intravenous calcium chloride as a routine intervention in out of hospital cardiac arrest is not associated with benefit and may cause harm. The optimal route for vascular access between peripheral intravenous versus intraosseous routes is currently the subject of two large randomised trials. Intracardiac, endobronchial, and intramuscular routes are not recommended. Central venous administration should be limited to patients where an existing central venous catheter is in situ and patent.
    MeSH term(s) Humans ; Epinephrine/pharmacology ; Epinephrine/therapeutic use ; Heart ; Norepinephrine ; Out-of-Hospital Cardiac Arrest ; Vasoconstrictor Agents/therapeutic use ; Heart Arrest/drug therapy
    Chemical Substances Epinephrine (YKH834O4BH) ; Norepinephrine (X4W3ENH1CV) ; Vasoconstrictor Agents
    Language English
    Publishing date 2023-03-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04301-3
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    Zs.A 5517: Show issues Location:
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  4. Article ; Online: Cardiac Arrest in the ICU: Measuring Performance to Drive Improvements in Care.

    Tomassini, Sara / Couper, Keith

    Chest

    2022  Volume 162, Issue 3, Page(s) 499–500

    MeSH term(s) Cardiopulmonary Resuscitation ; Heart Arrest/therapy ; Humans ; Intensive Care Units
    Language English
    Publishing date 2022-09-02
    Publishing country United States
    Document type Editorial
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2022.04.012
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    Ui III Zs.45: Show issues Location:
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    Zs.MO 349: Show issues

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  5. Article ; Online: Police response to out-of-hospital cardiac arrest: The importance of confidence.

    Mellor, Elizabeth / Couper, Keith

    Resuscitation

    2022  Volume 175, Page(s) 1–2

    MeSH term(s) Cardiopulmonary Resuscitation ; Defibrillators ; Emergency Medical Services ; Humans ; Out-of-Hospital Cardiac Arrest/therapy ; Police
    Language English
    Publishing date 2022-04-11
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2022.04.005
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    Zs.A 1048: Show issues Location:
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  6. Article ; Online: Resuscitation Plus Special Issue: Cardiac arrest research.

    Couper, Keith / Masterson, Siobhan / Nehme, Ziad

    Resuscitation plus

    2023  Volume 15, Page(s) 100416

    Language English
    Publishing date 2023-06-21
    Publishing country Netherlands
    Document type Editorial
    ISSN 2666-5204
    ISSN (online) 2666-5204
    DOI 10.1016/j.resplu.2023.100416
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  7. Book ; Online: RECOVERY Respiratory Support

    Couper, Keith

    http://isrctn.com/

    Respiratory Strategies in patients with coronavirus COVID-19- CPAP, High-flow, and standard care

    2020  

    Keywords covid19
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Book ; Online
    DOI 10.1186/isrctn16912075
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Noninvasive Respiratory Strategies and Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure Due to COVID-19-Reply.

    Couper, Keith / Connolly, Bronwen A / McAuley, Daniel F

    JAMA

    2022  Volume 327, Issue 20, Page(s) 2023–2024

    MeSH term(s) Acute Disease ; COVID-19/complications ; COVID-19/mortality ; Humans ; Hypoxia/etiology ; Hypoxia/therapy ; Intubation, Intratracheal/methods ; Noninvasive Ventilation/methods ; Oxygen Inhalation Therapy/methods ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/mortality ; Respiratory Insufficiency/therapy ; Respiratory Therapy/methods
    Language English
    Publishing date 2022-05-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2022.5279
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    Ua VI Zs.88: Show issues Location:
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  9. Article ; Online: COVID-19 and the global OHCA crisis: An urgent need for system level solutions.

    Christian, Michael D / Couper, Keith

    Resuscitation

    2020  Volume 157, Page(s) 274–276

    MeSH term(s) COVID-19 ; Humans ; Out-of-Hospital Cardiac Arrest/epidemiology ; Pandemics ; Registries ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-11-09
    Publishing country Ireland
    Document type Editorial ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2020.11.004
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    Zs.A 1048: Show issues Location:
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  10. Article ; Online: COVID-19: long-term effects on the community response to cardiac arrest?

    Perkins, Gavin D / Couper, Keith

    The Lancet. Public health

    2020  Volume 5, Issue 8, Page(s) e415–e416

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; France ; Humans ; Out-of-Hospital Cardiac Arrest ; Pandemics ; Paris ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ISSN 2468-2667
    ISSN (online) 2468-2667
    DOI 10.1016/S2468-2667(20)30134-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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