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  1. Article: Optimizing Endoscopic Bypass Procedures.

    Thompson, Christopher C

    Gastroenterology & hepatology

    2024  Volume 20, Issue 1, Page(s) 64–67

    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Response.

    Haseeb, Muhammad / Thompson, Christopher C

    Gastrointestinal endoscopy

    2023  Volume 98, Issue 1, Page(s) 140

    Language English
    Publishing date 2023-05-13
    Publishing country United States
    Document type Letter
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.03.012
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  3. Book: Bariatrics for the endoscopist

    Thompson, Christopher C.

    (Gastrointestinal endoscopy clinics of North America ; 21,2)

    2011  

    Author's details guest ed. Christopher C. Thompson
    Series title Gastrointestinal endoscopy clinics of North America ; 21,2
    Collection
    Language English
    Size XVI S., S. 190 - 350 : Ill., graph. Darst.
    Publisher Saunders an imprint of Elsevier
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT016872770
    ISBN 978-1-4557-0453-8 ; 1-4557-0453-9
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Bariatric endoscopy

    Thompson, Christopher C. / Ryan, Michele B.

    2013  

    Author's details Christopher Thompson ; Michele B. Ryan ed
    Language English
    Size XI, 245 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017570786
    ISBN 978-1-4419-1709-6 ; 9781441917102 ; 1-4419-1709-8 ; 1441917101
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Endoscopic therapy for gastroesophageal reflux disease: where are we, where are we going?

    Haseeb, Muhammad / Thompson, Christopher C

    Current opinion in gastroenterology

    2023  Volume 39, Issue 5, Page(s) 381–389

    Abstract: Purpose of review: Gastroesophageal reflux disease (GERD) is the most common chronic condition with increasing prevalence in the Western world. Despite medical therapy, a considerable proportion of patients continue to experience symptoms, thus fueling ... ...

    Abstract Purpose of review: Gastroesophageal reflux disease (GERD) is the most common chronic condition with increasing prevalence in the Western world. Despite medical therapy, a considerable proportion of patients continue to experience symptoms, thus fueling the demand for minimally invasive GERD treatment options. This review will assess the currently available endoscopic approaches by analyzing their outcomes data, indication for use and limitations.
    Recent findings: With increasing evidence of the safety and efficacy of endoscopic therapies, recent guidelines and consensus society documents have updated their recommendations for the endoscopic treatment of GERD. In this review, we have comprehensively assessed the current landscape of endoscopic approaches for the treatment of GERD and provided insight into future directions.
    Summary: Endoscopic therapies for GERD show promise as new treatments emerge and existing therapies evolve into safer and more reproducible options. They are well positioned to cater to a large subset of the population suffering from chronic condition of GERD.
    MeSH term(s) Humans ; Endoscopy ; Gastroesophageal Reflux/diagnosis
    Language English
    Publishing date 2023-07-20
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 632571-3
    ISSN 1531-7056 ; 0267-1379
    ISSN (online) 1531-7056
    ISSN 0267-1379
    DOI 10.1097/MOG.0000000000000968
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  6. Article ; Online: Isolated left sternocleidomastoid pyomyositis: a rare presentation of cervical sepsis.

    Fraser, Calum / Thompson, Christopher Sg / Yeo, Justin C L

    BMJ case reports

    2024  Volume 17, Issue 2

    Abstract: An elderly gentleman self-presented to A+E with a 7-day history of significant and progressive left-sided neck pain, swelling and fevers, despite oral antibiotics from his general practitioner. Examination revealed a large left-sided neck mass involving ... ...

    Abstract An elderly gentleman self-presented to A+E with a 7-day history of significant and progressive left-sided neck pain, swelling and fevers, despite oral antibiotics from his general practitioner. Examination revealed a large left-sided neck mass involving levels 2-5 of the neck that was firm to palpate, with erythematous overlying skin.An urgent CT scan demonstrated a large collection throughout the length of the left sternocleidomastoid muscle (SCM), measuring 13×5.5×4 cm, with extensive adjacent inflammatory change. He was subsequently taken to theatre for washout and debridement, during which the collection was found to be loculated and isolated to the SCM, with surrounding structures spared.Postoperatively, he was managed with intravenous fluids and a total of 2 weeks of intravenous antibiotics. The wound partially dehisced during healing and the cavity was packed with flaminal and regularly dressed with input from the tissue viability team. This was then left to heal by secondary intention and the patient was followed up in clinic over the following weeks to ensure resolution.
    MeSH term(s) Male ; Humans ; Aged ; Pyomyositis/diagnosis ; Pyomyositis/drug therapy ; Neck/diagnostic imaging ; Neck Muscles/diagnostic imaging ; Sepsis/drug therapy ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-257426
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  7. Article: Assessing implementation strategy and learning curve for transoral incisionless fundoplication as a new technique.

    Haseeb, Muhammad / Thompson, Christopher C

    Clinical endoscopy

    2022  Volume 55, Issue 6, Page(s) 751–752

    Language English
    Publishing date 2022-11-08
    Publishing country Korea (South)
    Document type Editorial ; Comment
    ZDB-ID 2643507-X
    ISSN 2234-2443 ; 2234-2400
    ISSN (online) 2234-2443
    ISSN 2234-2400
    DOI 10.5946/ce.2022.280
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  8. Article ; Online: Development of a novel endoscopic suturing simulator: validation and impact on clinical learning curve (with video).

    Jirapinyo, Pichamol / Thompson, Christopher C

    Gastrointestinal endoscopy

    2023  Volume 99, Issue 1, Page(s) 41–49

    Abstract: Background and aims: Endoscopic suturing is a complex skill with broad applications. The aim of this study was to develop and validate a novel endoscopic suturing simulator and scoring system for the purse-string suture pattern.: Methods: This was a ... ...

    Abstract Background and aims: Endoscopic suturing is a complex skill with broad applications. The aim of this study was to develop and validate a novel endoscopic suturing simulator and scoring system for the purse-string suture pattern.
    Methods: This was a prospective study of an endoscopic suturing simulator that consists of a circular opening representing a dilated gastrojejunal anastomosis of Roux-en-Y gastric bypass with 12 small target holes around its circumference. Purse-string suturing is performed in a counterclockwise fashion. Time allotted is 5 minutes, and each successful bite is awarded 10 points. Participants were divided into the novice, intermediate, and experienced groups. Validity evidence based on content, validity evidence based on other variables, and validity evidence based on consequences of testing were assessed.
    Results: Seventeen subjects (3 novice, 7 intermediate, and 7 experienced) participated in the study. Validity evidence based on content: The content validity index for realism, relevance, and representativeness was 0.89, 1.00, and 1.00, respectively. Validity evidence based on other variables: The novice, intermediate, and experienced groups scored 30.0 ± 8.2, 57.1 ± 28.1, and 131.2 ± 51.7 (P = .001). Validity evidence based on consequences of testing: The simulator group required 5 ± 5 transoral outlet reduction cases before being able to independently complete an entire purse-string, whereas the non-simulator group required 38 ± 11 clinical cases (P < .0001).
    Conclusions: This novel endoscopic suturing simulator seems realistic, relevant, and representative of the clinical suturing experience. In addition, it seems effective at objectively assessing suturing skills and shortening the clinical learning curve.
    MeSH term(s) Humans ; Learning Curve ; Prospective Studies ; Endoscopy ; Gastric Bypass ; Reoperation ; Suture Techniques ; Clinical Competence ; Laparoscopy
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Video-Audio Media ; Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.07.045
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  9. Article ; Online: Maternal depression and child telomere length: The role of genetic sensitivity.

    Thompson, Amanda J / Henrich, Christopher C

    Journal of affective disorders

    2023  Volume 334, Page(s) 77–82

    Abstract: Background: The stress of a mother's depression may increasingly tax psychobiological systems that help children with self-regulation, increasing children's allostatic load over time. Some evidence supports children exposed to maternal depression tend ... ...

    Abstract Background: The stress of a mother's depression may increasingly tax psychobiological systems that help children with self-regulation, increasing children's allostatic load over time. Some evidence supports children exposed to maternal depression tend to have shorter telomeres and tend to have more somatic and psychological problems. Children having one or more A1 alleles of dopamine receptor 2 (DRD2, rs1800497), tend to have greater sensitivity to maternal depression and could experience more adverse child outcomes that contribute to greater allostatic load.
    Methods: Using the Future Families and Child Wellbeing dataset, secondary-data analyses were used to test the effect of repeated exposure to maternal depression during early childhood on children's telomere length during middle childhood moderated by children's DRD2 genotype (N = 2884).
    Results: Greater maternal depression was not significantly associated with shorter child telomere length and this association was not moderated by DRD2 genotypes while controlling for factors associated with child telomere length.
    Implications: The effect of maternal depression on children's TL may not be significant in populations from diverse racial-ethnic and family backgrounds during middle childhood. These findings could help further our current understanding psychobiological systems affected by maternal depression that result in adverse child outcomes.
    Limitations: Even though this study used a relatively large and diverse sample, replication of DRD2 moderation in even larger samples is an important next step.
    MeSH term(s) Humans ; Child ; Child, Preschool ; Female ; Telomere Shortening/genetics ; Family ; Telomere/genetics ; Mothers/psychology
    Language English
    Publishing date 2023-05-03
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2023.04.103
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  10. Article ; Online: Combining transoral outlet reduction with pharmacotherapy yields similar 1-year efficacy with improved safety compared with surgical revision for weight regain after Roux-en-Y gastric bypass (with videos).

    Jirapinyo, Pichamol / Thompson, Christopher C

    Gastrointestinal endoscopy

    2023  Volume 98, Issue 4, Page(s) 552–558

    Abstract: Background and aims: Transoral outlet reduction (TORe) and antiobesity medication (AOM) are effective treatments for weight regain after Roux-en-Y gastric bypass (RYGB). This study aims to assess the efficacy of combination therapy (TORe + AOM) for ... ...

    Abstract Background and aims: Transoral outlet reduction (TORe) and antiobesity medication (AOM) are effective treatments for weight regain after Roux-en-Y gastric bypass (RYGB). This study aims to assess the efficacy of combination therapy (TORe + AOM) for treating weight regain and to compare the safety and efficacy of combination therapy with AOM alone, TORe alone, and surgical revision of RYGB.
    Methods: This was a retrospective study of RYGB patients with weight regain who underwent combination therapy, defined as initiation of at least 1 AOM within 6 months before or after TORe. Outcomes were weight loss after combination therapy and comparison of combination therapy with AOM alone, TORe alone, and surgical revision.
    Results: One hundred forty-five RYGB patients underwent combination therapy. Most commonly prescribed AOMs were topiramate, phentermine/topiramate, phentermine, and liraglutide. At 12 months, patients experienced 15.2% ± 7.4% total weight loss (TWL). Ninety percent of patients achieved ≥5% TWL at 12 months. Combination therapy was associated with greater weight loss than AOM alone (15.2% ± 7.4% vs 6.8% ± 8.2% TWL, P < .0001) or TORe alone (15.2% ± 7.4% vs 8.7% ± 8.3% TWL, P < .0001), with similar serious adverse event rates (2.1% vs 4.7% vs .6% for combination therapy vs AOM alone vs TORe alone, P > .05). Combination therapy yielded similar weight loss to surgical revision (15.2% ± 7.4% vs 16.4% ± 13.1% TWL, P = .34), with a lower serious adverse event rate (2.1% vs 14.3%, P = .0004).
    Conclusions: Combination of TORe with AOM is superior to either therapy alone, providing similar efficacy to surgical revision with a better safety profile for the treatment of weight regain after RYGB.
    MeSH term(s) Humans ; Reoperation ; Gastric Bypass ; Retrospective Studies ; Topiramate ; Phentermine ; Weight Loss ; Weight Gain
    Chemical Substances Topiramate (0H73WJJ391) ; Phentermine (C045TQL4WP)
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.04.2092
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