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  1. Article ; Online: Combined immunotherapy and VEGF-antagonist in hepatocellular carcinoma: a step forward.

    Bhoori, Sherrie / Mazzaferro, Vincenzo

    The Lancet. Oncology

    2020  Volume 21, Issue 6, Page(s) 740–741

    MeSH term(s) Antibodies, Monoclonal, Humanized ; Bevacizumab ; Carcinoma, Hepatocellular ; Humans ; Immunotherapy ; Liver Neoplasms ; Vascular Endothelial Growth Factor A
    Chemical Substances Antibodies, Monoclonal, Humanized ; Vascular Endothelial Growth Factor A ; Bevacizumab (2S9ZZM9Q9V) ; atezolizumab (52CMI0WC3Y)
    Language English
    Publishing date 2020-06-04
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(20)30211-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5696: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 460: Show issues

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  2. Article: Hepatocellular Carcinoma Recurrence After Liver Transplantation.

    Gabutti, Alejandro / Bhoori, Sherrie / Cascella, Tommaso / Bongini, Marco

    Oncology (Williston Park, N.Y.)

    2020  Volume 34, Issue 3

    Abstract: Key Points • Recurrent HCC after OLT management is challenging and notoriously difficult. • High oncologic-risk patient identification and close follow-up are essential. • Recurrences diagnosed within the first 2 years after OLT can be classified as ... ...

    Abstract Key Points • Recurrent HCC after OLT management is challenging and notoriously difficult. • High oncologic-risk patient identification and close follow-up are essential. • Recurrences diagnosed within the first 2 years after OLT can be classified as early-onset and are associated with poor prognosis. • Surgical resection should be the first curative attempt when it is technically feasible. • TACE in patients who have undergone OLT appears to be effective and safe. • Sorafenib can be used as systemic therapy in cases with multi-organ recurrence; newer therapies are emerging. • The benefit of immunosuppression with an mTOR inhibitor has not been established. • In the posttransplant setting, a combination treatment approach is warranted.
    MeSH term(s) Carcinoma, Hepatocellular/etiology ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/surgery ; Combined Modality Therapy ; Female ; Hepatitis C/pathology ; Humans ; Liver Neoplasms/etiology ; Liver Neoplasms/pathology ; Liver Neoplasms/surgery ; Liver Transplantation ; Middle Aged ; Neoplasm Recurrence, Local/etiology ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/therapy ; Risk Factors ; Treatment Outcome
    Language English
    Publishing date 2020-03-19
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1067950-9
    ISSN 0890-9091
    ISSN 0890-9091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3168: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Zs.MO 372: Show issues

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  3. Article: Liver Transplantation for Hepatic Metastases from Colorectal Cancer: Current Knowledge and Open Issues.

    Maspero, Marianna / Sposito, Carlo / Virdis, Matteo / Citterio, Davide / Pietrantonio, Filippo / Bhoori, Sherrie / Belli, Filiberto / Mazzaferro, Vincenzo

    Cancers

    2023  Volume 15, Issue 2

    Abstract: More than 40% of patients with colorectal cancer present liver metastases (CRLM) during the course of their disease and up to 50% present with unresectable disease. Without surgical interventions, survival for patients treated with systemic therapies ... ...

    Abstract More than 40% of patients with colorectal cancer present liver metastases (CRLM) during the course of their disease and up to 50% present with unresectable disease. Without surgical interventions, survival for patients treated with systemic therapies alone is dismal. In the past, liver transplantation (LT) for patients with unresectable CRLM failed to show any survival benefit due to poor selection, ineffective chemotherapeutic regimens, unbalanced immunosuppression and high perioperative mortality. Since then and for many years LT for CRLM was abandoned. The turning point occurred in 2013, when the results from the Secondary Cancer (SECA I) pilot study performed at Oslo University were published reporting a 60% 5-year overall survival after LT in patients with unresectable CRLM. These results effectively reignited the interest in LT as a potential therapy for CRLM, and several trials are undergoing. The aims of this article are to give a comprehensive overview of the available evidence on LT for CRLM, discuss the open issues in this rapidly evolving field, and highlight possible ways to address the future of this fascinating therapeutic alternative for selected patients with CRLM.
    Language English
    Publishing date 2023-01-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15020345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Y

    Rivoltini, Licia / Bhoori, Sherrie / Camisaschi, Chiara / Bergamaschi, Laura / Lalli, Luca / Frati, Paola / Citterio, Davide / Castelli, Chiara / Mazzaferro, Vincenzo

    Gut

    2022  Volume 72, Issue 2, Page(s) 406–407

    MeSH term(s) Humans ; Carcinoma, Hepatocellular/radiotherapy ; Liver Neoplasms/radiotherapy ; Embolization, Therapeutic ; Immunotherapy
    Language English
    Publishing date 2022-05-04
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2021-326869
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 160: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: COVID-19 in long-term liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy.

    Bhoori, Sherrie / Rossi, Roberta Elisa / Citterio, Davide / Mazzaferro, Vincenzo

    The lancet. Gastroenterology & hepatology

    2020  Volume 5, Issue 6, Page(s) 532–533

    MeSH term(s) Aged ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/mortality ; Humans ; Immunosuppressive Agents/administration & dosage ; Immunosuppressive Agents/adverse effects ; Italy/epidemiology ; Liver Transplantation/adverse effects ; Liver Transplantation/mortality ; Male ; Pandemics ; Pneumonia, Viral/mortality ; SARS-CoV-2 ; Transplant Recipients/statistics & numerical data
    Chemical Substances Immunosuppressive Agents
    Keywords covid19
    Language English
    Publishing date 2020-04-09
    Publishing country Netherlands
    Document type Letter
    ISSN 2468-1253
    ISSN (online) 2468-1253
    DOI 10.1016/S2468-1253(20)30116-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Alpha-fetoprotein in liver transplantation for hepatocellular carcinoma: The lower, the better.

    Mazzaferro, Vincenzo / Droz Dit Busset, Michele / Bhoori, Sherrie

    Hepatology (Baltimore, Md.)

    2018  Volume 68, Issue 2, Page(s) 775–777

    MeSH term(s) Carcinoma, Hepatocellular ; Humans ; Liver Cirrhosis ; Liver Neoplasms ; Liver Transplantation ; alpha-Fetoproteins
    Chemical Substances alpha-Fetoproteins
    Language English
    Publishing date 2018-05-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1002/hep.29835
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1660: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: European Society of Organ Transplantation (ESOT) Consensus Report on Downstaging, Bridging and Immunotherapy in Liver Transplantation for Hepatocellular Carcinoma.

    Claasen, Marco Petrus Adrianus Wilhelmus / Sneiders, Dimitri / Rakké, Yannick Sebastiaan / Adam, René / Bhoori, Sherrie / Cillo, Umberto / Fondevila, Constantino / Reig, Maria / Sapisochin, Gonzalo / Tabrizian, Parissa / Toso, Christian

    Transplant international : official journal of the European Society for Organ Transplantation

    2023  Volume 36, Page(s) 11648

    Abstract: Liver transplantation offers the best chance of cure for most patients with non-metastatic hepatocellular carcinoma (HCC). Although not all patients with HCC are eligible for liver transplantation at diagnosis, some can be downstaged using locoregional ... ...

    Abstract Liver transplantation offers the best chance of cure for most patients with non-metastatic hepatocellular carcinoma (HCC). Although not all patients with HCC are eligible for liver transplantation at diagnosis, some can be downstaged using locoregional treatments such as ablation and transarterial chemoembolization. These aforementioned treatments are being applied as bridging therapies to keep patients within transplant criteria and to avoid them from dropping out of the waiting list while awaiting a liver transplant. Moreover, immunotherapy might have great potential to support downstaging and bridging therapies. To address the contemporary status of downstaging, bridging, and immunotherapy in liver transplantation for HCC, European Society of Organ Transplantation (ESOT) convened a dedicated working group comprised of experts in the treatment of HCC to review literature and to develop guidelines pertaining to this cause that were subsequently discussed and voted during the Transplant Learning Journey (TLJ) 3.0 Consensus Conference that took place in person in Prague. The findings and recommendations of the working group on Downstaging, Bridging and Immunotherapy in Liver Transplantation for Hepatocellular Carcinoma are presented in this article.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/surgery ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/surgery ; Liver Neoplasms/pathology ; Liver Transplantation/adverse effects ; Treatment Outcome ; Chemoembolization, Therapeutic/adverse effects ; Neoadjuvant Therapy/adverse effects ; Neoplasm Staging ; Immunotherapy
    Language English
    Publishing date 2023-09-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.3389/ti.2023.11648
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2358: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: COVID-19 in long-term liver transplant patients

    Bhoori, Sherrie / Rossi, Roberta Elisa / Citterio, Davide / Mazzaferro, Vincenzo

    The Lancet Gastroenterology & Hepatology

    preliminary experience from an Italian transplant centre in Lombardy

    2020  Volume 5, Issue 6, Page(s) 532–533

    Keywords Hepatology ; Gastroenterology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2468-1253
    DOI 10.1016/s2468-1253(20)30116-3
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: COVID-19 in long-term liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy

    Bhoori, Sherrie / Rossi, Roberta Elisa / Citterio, Davide / Mazzaferro, Vincenzo

    Lancet Gastroenterol Hepatol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #47825
    Database COVID19

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  10. Article: Carcinoid Syndrome and Hyperinsulinemic Hypoglycemia Associated with Neuroendocrine Neoplasms: A Critical Review on Clinical and Pharmacological Management.

    Spada, Francesca / Rossi, Roberta E / Kara, Elda / Laffi, Alice / Massironi, Sara / Rubino, Manila / Grimaldi, Franco / Bhoori, Sherrie / Fazio, Nicola

    Pharmaceuticals (Basel, Switzerland)

    2021  Volume 14, Issue 6

    Abstract: The carcinoid syndrome (CS) and hyperinsulinemic hypoglycemia (HH) represent two of the most common clinical syndromes associated with neuroendocrine neoplasms (NENs). The former is mainly related to the serotonin secretion by a small bowel NEN, whereas ... ...

    Abstract The carcinoid syndrome (CS) and hyperinsulinemic hypoglycemia (HH) represent two of the most common clinical syndromes associated with neuroendocrine neoplasms (NENs). The former is mainly related to the serotonin secretion by a small bowel NEN, whereas the latter depends on an insulin hypersecretion by a pancreatic insulinoma. Both syndromes/conditions can affect prognosis and quality of life of patients with NENs. They are often diagnosed late when patients become strongly symptomatic. Therefore, their early detection and management are a critical step in the clinical management of NEN patients. A dedicated and experienced multidisciplinary team with appropriate therapeutic strategies is needed and should be encouraged to optimize clinical outcomes. This review aims to critically analyze clinical features, evidence and treatment options of CS and HH and therefore to improve their management.
    Language English
    Publishing date 2021-06-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph14060539
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