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  1. Article ; Online: Editorial: Assessing the value and cost of Organ Donation and Transplantation (ODT).

    Gitto, Lara / Favi, Evaldo / Giorgakis, Emmanouil / Cacciola, Roberto

    Frontiers in public health

    2024  Volume 12, Page(s) 1388317

    MeSH term(s) Humans ; Tissue and Organ Procurement ; Tissue Donors ; Organ Transplantation
    Language English
    Publishing date 2024-03-19
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1388317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Negative COVID-19 Plasma PCR Following COVID-19+ Donor Kidney Transplant.

    Hardgrave, Hailey / Burdine, Lyle / Patel, Raj / Giorgakis, Emmanouil

    Transplantation

    2022  Volume 106, Issue 9, Page(s) e422–e423

    MeSH term(s) COVID-19 ; COVID-19 Testing ; Humans ; Kidney Transplantation/adverse effects ; Polymerase Chain Reaction ; SARS-CoV-2 ; Tissue Donors ; Transplant Recipients
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Letter
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 488: Show issues Location:
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  3. Article ; Online: Organ Reconditioning and Machine Perfusion in Transplantation.

    Bellini, Maria Irene / Bonaccorsi Riani, Eliano / Giorgakis, Emmanouil / Kaisar, Maria E / Patrono, Damiano / Weissenbacher, Annemarie

    Transplant international : official journal of the European Society for Organ Transplantation

    2023  Volume 36, Page(s) 11100

    MeSH term(s) Humans ; Perfusion ; Kidney Transplantation ; Organ Preservation
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.3389/ti.2023.11100
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    Zs.A 2358: Show issues Location:
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  4. Article: Gut microbiome dysbiosis in the setting of solid organ transplantation: What we have gleaned from human and animal studies.

    Sharma, Aparna / Giorgakis, Emmanouil

    World journal of transplantation

    2020  Volume 12, Issue 7, Page(s) 157–162

    Abstract: The human gut microbiome refers to all of the microorganisms present throughout the length of the gastrointestinal tract. Gut flora influence host metabolic and immune processes in myriad ways. They also play an important role in maturation and ... ...

    Abstract The human gut microbiome refers to all of the microorganisms present throughout the length of the gastrointestinal tract. Gut flora influence host metabolic and immune processes in myriad ways. They also play an important role in maturation and modulation of the immune system. Dysbiosis or a pathologic alteration in gut flora has been implicated in a number of diseases ranging from metabolic, autoimmune and degenerative. Whether dysbiosis has similar implications in organ transplant has been the focus of a number of pre-clinical and clinical studies. Researchers have observed significant microbiome changes after solid organ transplantation in humans that have been associated with clinical outcomes such as post-transplant urinary tract infections and diarrhea. In this article, we will discuss the available data regarding pathologic alterations in gut microbiome (dysbiosis) in solid organ transplant recipients as well as some of challenges in this field. We will also discuss animal studies focusing on mouse models of transplantation that shed light on the underlying mechanisms that explain these findings.
    Language English
    Publishing date 2020-02-19
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2220-3230
    ISSN 2220-3230
    DOI 10.5500/wjt.v12.i7.157
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  5. Article ; Online: Expedited placement to maximize utilization of marginal organs.

    Giorgakis, Emmanouil / Mathur, Amit K

    Current opinion in organ transplantation

    2020  Volume 25, Issue 6, Page(s) 640–646

    Abstract: Purpose of review: Deceased donation represents the largest supply of organs for transplant in the United States. Organs with suboptimal characteristics related to donor disease or recovery-related issues are increasingly discarded at the time of ... ...

    Abstract Purpose of review: Deceased donation represents the largest supply of organs for transplant in the United States. Organs with suboptimal characteristics related to donor disease or recovery-related issues are increasingly discarded at the time of recovery, prompting late allocation to candidates later in the match sequence. Late allocation contributes to organ injury by prolonging cold ischemia, which may further lead to the risk of organ discard, despite the potential to provide benefit to certain transplant candidates.
    Recent findings: Expedited placement of marginal organs has emerged as a strategy to address the growing problem of organ discard of marginal organs that have been declined late after recovery. In this review, we describe the basis for expedited organ placement, and approaches to facilitating placement of these grafts, drawing examples from kidney and liver donation and transplantation globally.
    Summary: There is significant global variation in practice related to late allocation. Multiple policy mechanisms exist to facilitate expedited placement, including simultaneous offers to multiple centers, predesignation of aggressive centers, and increasing organ procurement organization autonomy in late allocation. Optimizing late allocation of deceased donor organs holds significant promise to increase the number of transplants.
    MeSH term(s) Humans ; Tissue and Organ Procurement/methods
    Language English
    Publishing date 2020-10-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1390429-2
    ISSN 1531-7013 ; 1087-2418
    ISSN (online) 1531-7013
    ISSN 1087-2418
    DOI 10.1097/MOT.0000000000000827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5609: Show issues Location:
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  6. Article ; Online: Application of resuscitative endovascular balloon occlusion in post-transplant mycotic hepatic artery pseudoaneurysm rupture in the setting of

    Stephenson, Krista / Kalkwarf, Kyle / Giorgakis, Emmanouil

    Annals of hepato-biliary-pancreatic surgery

    2021  Volume 25, Issue 1, Page(s) 126–131

    Abstract: Hepatic artery pseudoaneurysm (HAP) is a rare, highly morbid and frequently fatal complication of liver transplantation. Most are a mycotic mediated weakness of the arterial wall, with associated bacterial or fungal infection of ascitic fluid. As it is ... ...

    Abstract Hepatic artery pseudoaneurysm (HAP) is a rare, highly morbid and frequently fatal complication of liver transplantation. Most are a mycotic mediated weakness of the arterial wall, with associated bacterial or fungal infection of ascitic fluid. As it is usually asymptomatic prior to rupture, the majority present in acute hemorrhagic shock and dire extremis. Resuscitative endovascular balloon occlusion (REBOA) was initially developed for the management of noncompressible hemorrhagic shock in trauma; however, remains underutilized and understudied in the non-trauma setting. We present the case of a mycotic hepatic artery pseudoaneurysm rupture due to
    Language English
    Publishing date 2021-03-01
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 3012179-6
    ISSN 2508-5859 ; 2508-5778
    ISSN (online) 2508-5859
    ISSN 2508-5778
    DOI 10.14701/ahbps.2021.25.1.126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass.

    Gottsponer, Josephine A / Baker, David L / Osborn, Tamara / Estrada, Martha M / Giorgakis, Emmanouil / Burdine, Lyle J / Patel, Raj B

    Journal of surgical case reports

    2023  Volume 2023, Issue 2, Page(s) rjad050

    Abstract: A 56-year-old woman with past medical history significant for bariatric Roux-en-Y gastric bypass 3 years prior presented for evaluation of an 8-month history of severe hypoglycemia relieved by intake of carbohydrates associated with syncopal episodes. ... ...

    Abstract A 56-year-old woman with past medical history significant for bariatric Roux-en-Y gastric bypass 3 years prior presented for evaluation of an 8-month history of severe hypoglycemia relieved by intake of carbohydrates associated with syncopal episodes. Inpatient workup revealed endogenous hyperinsulinemia concerning for insulinoma vs. nesidioblastosis. She successfully underwent pancreaticoduodenectomy (Whipple procedure), and pathology report confirmed scattered low-grade intraepithelial neoplasia within the pancreatic parenchyma consistent with nesidioblastosis. The patient has had satisfactory control of glucose levels 30 days out from surgery.
    Language English
    Publishing date 2023-02-17
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjad050
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  8. Article ; Online: Horseshoe kidney transplantation.

    Osborn, Tamara / Hardgrave, Hailey / Spencer-Cole, Richard / Klutts, Garrett / Nigh, Joseph / Giorgakis, Emmanouil

    ANZ journal of surgery

    2021  Volume 92, Issue 7-8, Page(s) 1919–1920

    MeSH term(s) Fused Kidney/complications ; Fused Kidney/diagnostic imaging ; Fused Kidney/surgery ; Humans ; Kidney ; Kidney Transplantation
    Language English
    Publishing date 2021-11-18
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.17380
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 180: Show issues Location:
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  9. Article ; Online: Early Outcomes of Ruxolitinib in the Treatment of Steroid Refractory Graft-versus-host Disease on Liver Transplant Recipients.

    Kakadia, Sunilkumar / Trotta, Holly / Kurczek, Leslie / Burdine, Lyle / Veeraputhiran, Muthu / Giorgakis, Emmanouil

    Transplantation

    2021  Volume 104, Issue 8, Page(s) e247

    MeSH term(s) Graft vs Host Disease ; Hematopoietic Stem Cell Transplantation ; Humans ; Liver Transplantation ; Pyrazoles
    Chemical Substances Pyrazoles ; ruxolitinib (82S8X8XX8H)
    Language English
    Publishing date 2021-07-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000003252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Acuity circles allocation policy impact on waitlist mortality and donation after circulatory death liver transplantation: A nationwide retrospective analysis.

    Giorgakis, Emmanouil / Ivanics, Tommy / Wallace, David / Wells, Allison / Balogh, Julius / Hardgrave, Hailey / Krinock, Derek / Klutts, Garrett / Burdine, Lyle / Singer, Andrew / Mathur, Amit

    Health science reports

    2023  Volume 6, Issue 2, Page(s) e1066

    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article
    ISSN 2398-8835
    ISSN (online) 2398-8835
    DOI 10.1002/hsr2.1066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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