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  1. Article ; Online: SPIKES: Breaking bad news in the emergency department.

    Rivera, Megan / Yang, Thomas / Moadel, Tiffany / Corbo, Samuel / Natesan, Sreeja

    AEM education and training

    2024  Volume 8, Issue 2, Page(s) e10977

    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type News
    ISSN 2472-5390
    ISSN (online) 2472-5390
    DOI 10.1002/aet2.10977
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Author reply: Letter to the editor on "A matched cohort study investigating premature, accentuated, and accelerated aging in people living with HIV".

    Gooden, Tiffany E / Nirantharakumar, Krishnarajah / Thomas, G Neil

    HIV medicine

    2023  Volume 24, Issue 11, Page(s) 1165

    Language English
    Publishing date 2023-10-04
    Publishing country England
    Document type Letter
    ZDB-ID 2001932-4
    ISSN 1468-1293 ; 1464-2662
    ISSN (online) 1468-1293
    ISSN 1464-2662
    DOI 10.1111/hiv.13560
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  3. Article ; Online: Big data in Earth science: Emerging practice and promise.

    Vance, Tiffany C / Huang, Thomas / Butler, Kevin A

    Science (New York, N.Y.)

    2024  Volume 383, Issue 6688, Page(s) eadh9607

    Abstract: Improvements in the number and resolution of Earth- and satellite-based sensors coupled with finer-resolution models have resulted in an explosion in the volume of Earth science data. This data-rich environment is changing the practice of Earth science, ... ...

    Abstract Improvements in the number and resolution of Earth- and satellite-based sensors coupled with finer-resolution models have resulted in an explosion in the volume of Earth science data. This data-rich environment is changing the practice of Earth science, extending it beyond discovery and applied science to new realms. This Review highlights recent big data applications in three subdisciplines-hydrology, oceanography, and atmospheric science. We illustrate how big data relate to contemporary challenges in science: replicability and reproducibility and the transition from raw data to information products. Big data provide unprecedented opportunities to enhance our understanding of Earth's complex patterns and interactions. The emergence of digital twins enables us to learn from the past, understand the current state, and improve the accuracy of future predictions.
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.adh9607
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  4. Article: Risks Associated with Quality Care among Hispanic and White Populations-A Cross-Sectional Comparison Study.

    Tzeng, Ching-Fang Tiffany / Swoboda, Thomas / Huggins, Charles / D'Etienne, James / Wang, Hao

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 2

    Abstract: Quality care in healthcare is a multifaceted concept that encompasses the execution of effective medical treatments and the patient's overall experience. It involves a multitude of factors, including effectiveness, safety, timeliness, equity, and patient ...

    Abstract Quality care in healthcare is a multifaceted concept that encompasses the execution of effective medical treatments and the patient's overall experience. It involves a multitude of factors, including effectiveness, safety, timeliness, equity, and patient centeredness, which are important in shaping the healthcare landscape. This cross-sectional study used the data from the Health Information National Trends Survey 6 (HINTS 6), which collects data on various aspects of health communication and information-seeking behaviors, to investigate the factors associated with quality care among White and Hispanic populations. All adults who participated in HINTS 6 and visited healthcare service at least once in the past 12 months were included in this study. Multivariable logistic regression was used to determine the association between quality care and delay or discriminated care with the adjustment of all other sociodemographic variables. We analyzed a total of 3611 participants. Poor social determinants of health (SDOHs) (OR 0.61, CI 0.43-0.88,
    Language English
    Publishing date 2024-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12020250
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  5. Article ; Online: Characterization of a novel mouse platelet transfusion model.

    Gordy, Dominique / Swayne, Theresa / Berry, Gregory J / Thomas, Tiffany A / Hudson, Krystalyn E / Stone, Elizabeth F

    Vox sanguinis

    2024  

    Abstract: Background and objectives: Platelet transfusions are increasing with medical advances. Based on FDA criteria, platelet units are assessed by in vitro measures; however, it is not known how platelet processing and storage duration affect function in vivo. ...

    Abstract Background and objectives: Platelet transfusions are increasing with medical advances. Based on FDA criteria, platelet units are assessed by in vitro measures; however, it is not known how platelet processing and storage duration affect function in vivo. Our study's aim was to develop a novel platelet transfusion model stored in mouse plasma that meets FDA criteria adapted to mice, and transfused fresh and stored platelets are detectable in clots in vivo.
    Study design and methods: Platelet units stored in mouse plasma were prepared using a modified platelet-rich plasma (PRP) collection protocol. Characteristics of fresh and stored units, including pH, cell count, in vitro measures of activity, including activation and aggregation, and post-transfusion recovery (PTR), were determined. Lastly, a tail transection assay was conducted using mice transfused with fresh or stored units, and transfused platelets were identified by confocal imaging.
    Results: Platelet units had acceptable platelet and white cell counts and were negative for bacterial contamination. Fresh and 1-day stored units had acceptable pH; the platelets were activatable by thrombin and adenosine diphosphate, agreeable with thrombin, had acceptable PTR, and were present in vivo in clots of recipients after tail transection. In contrast, 2-day stored units had clinically unacceptable quality.
    Conclusion: We developed mouse platelets for transfusion analogous to human platelet units using a modified PRP collection protocol with maximum storage of 1 day for an 'old' unit. This provides a powerful tool to test how process modifications and storage conditions affect transfused platelet function in vivo.
    Language English
    Publishing date 2024-04-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 80313-3
    ISSN 1423-0410 ; 0042-9007
    ISSN (online) 1423-0410
    ISSN 0042-9007
    DOI 10.1111/vox.13642
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  6. Article ; Online: Interventions to prevent and mitigate workplace violence: Teaming up for a safer environment.

    Sanders, Jennifer / Thomas, Lisa / Kerr, Tarra / Benita, Tiffany / Abela, Karla / Ulrich, Beth

    Nursing management

    2023  Volume 54, Issue 8, Page(s) 20–30

    MeSH term(s) Workplace Violence/prevention & control ; Workplace
    Language English
    Publishing date 2023-07-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605889-9
    ISSN 1538-8670 ; 0744-6314
    ISSN (online) 1538-8670
    ISSN 0744-6314
    DOI 10.1097/nmg.0000000000000040
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  7. Article ; Online: Development of a Management App for Postviral Fibromyalgia-Like Symptoms: Patient Preference-Guided Approach.

    Blanchard, Marc / Koller, Cinja Nadana / Azevedo, Pedro Ming / Prétat, Tiffany / Hügle, Thomas

    JMIR formative research

    2024  Volume 8, Page(s) e50832

    Abstract: Background: Persistent fibromyalgia-like symptoms have been increasingly reported following viral infections, including SARS-CoV-2. About 30% of patients with post-COVID-19 syndrome fulfill the fibromyalgia criteria. This complex condition presents ... ...

    Abstract Background: Persistent fibromyalgia-like symptoms have been increasingly reported following viral infections, including SARS-CoV-2. About 30% of patients with post-COVID-19 syndrome fulfill the fibromyalgia criteria. This complex condition presents significant challenges in terms of self-management. Digital health interventions offer a viable means to assist patients in managing their health conditions. However, the challenge of ensuring their widespread adoption and adherence persists. This study responds to this need by developing a patient-centered digital health management app, incorporating patient preferences to enhance usability and effectiveness, ultimately aiming to improve patient outcomes and quality of life.
    Objective: This research aims to develop a digital health self-management app specifically for patients experiencing postviral fibromyalgia-like symptoms. By prioritizing patient preferences and engagement through the app's design and functionality, the study intends to facilitate better self-management practices and improve adherence.
    Methods: Using an exploratory study design, the research used patient preference surveys and usability testing as primary tools to inform the development process of the digital health solution. We gathered and analyzed patients' expectations regarding design features, content, and usability to steer the iterative app development.
    Results: The study uncovered crucial insights from patient surveys and usability testing, which influenced the app's design and functionality. Key findings included a preference for a symptom list over an automated chatbot, a desire to report on a moderate range of symptoms and activities, and the importance of an intuitive onboarding process. While usability testing identified some challenges in the onboarding process, it also confirmed the importance of aligning the app with patient needs to enhance engagement and satisfaction.
    Conclusions: Incorporating patient feedback has been a significant factor in the development of the digital health app. Challenges encountered with user onboarding during usability testing have highlighted the importance of this process for user adoption. The study acknowledges the role of patient input in developing digital health technologies and suggests further research to improve onboarding procedures, aiming to enhance patient engagement and their ability to manage digital health resources effectively.
    International registered report identifier (irrid): RR2-10.2196/32193.
    Language English
    Publishing date 2024-04-19
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-326X
    ISSN (online) 2561-326X
    DOI 10.2196/50832
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  8. Article ; Online: Modeling Hawaiian Agroecology

    Noa Kekuewa Lincoln / Thomas P. Haensel / Tiffany M. Lee

    Frontiers in Sustainable Food Systems, Vol

    Depicting traditional adaptation to the world's most diverse environment

    2023  Volume 7

    Abstract: Most neglected and underutilized crops were developed and utilized within indigenous agroecological cropping systems. While crop suitability must consider the constraints of the environment, the conditions of agroecological systems and the role of crops ... ...

    Abstract Most neglected and underutilized crops were developed and utilized within indigenous agroecological cropping systems. While crop suitability must consider the constraints of the environment, the conditions of agroecological systems and the role of crops within those systems should be considered. Such consideration may guide the implementation of appropriate farming systems specific to different ecosystems and microhabitats. Using the Hawaiian archipelago as a model system of socioecological dynamics, we consider the distribution of agroecological systems and their associated crops to explore how agroecological suitability changes across climate, topography, and soils. We conduct spatial modeling of the potential nature and extent of seven agroecological archetypes based on historical records. The seven spatial models of pre-colonial agroecological systems produced extents distributed across much of the Hawaiian archipelago, with clear adaptive patterns within and across the islands. The distribution of cropping system further affects the appropriateness of crop species application. We argue that the consideration of agroecological niches and associated cropping systems is critical for realizing the potential of underutilized crops and improving the efficiency of contemporary agricultural systems.
    Keywords adaptation ; agroecology ; agroforestry ; biocultural ; cropping systems ; indigenous agriculture ; Nutrition. Foods and food supply ; TX341-641 ; Food processing and manufacture ; TP368-456
    Subject code 571
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Warren Alpert Medical School of Brown University Annual Research Forum

    Jonathan Ho / Mica Kane / Mohammed Haji / Nirav Haribhakti / Thomas Fritz Siegert / Tiffany Ho / Matthew Murphy

    Brown Journal of Hospital Medicine, Vol 2, Iss

    Resident Project Winners

    2023  Volume 3

    Keywords Medicine ; R
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Department of Medicine, Warren Alpert Medical School at Brown University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Évaluation de la fibromyalgie secondaire à la polyarthrite rhumatoïde ou la spondylarthrite.

    Ming Azevedo, Pedro / Prétat, Tiffany / Hügle, Thomas

    Revue medicale suisse

    2022  Volume 18, Issue 773, Page(s) 477–481

    Abstract: Pain is one of the main factors assessed in most of the scores used to measure activity in rheumatoid arthritis (RA) and spondylo arthritis (SpA). However, the experience of pain is complex, subjective and influenced by many factors. Fibromyalgia (FM) is ...

    Title translation Assessment of secondary fibromyalgia in patients with rheumatoid arthritis or spondylarthritis.
    Abstract Pain is one of the main factors assessed in most of the scores used to measure activity in rheumatoid arthritis (RA) and spondylo arthritis (SpA). However, the experience of pain is complex, subjective and influenced by many factors. Fibromyalgia (FM) is present in 16-38% of patients with inflammatory rheumatic diseases (IRD) and has been shown to significantly increase indices of disease activity, often preventing an adequate response to immunosuppressive treatments. Recognition of secondary FM is important to avoid overtreatment. This article explores the relationship between FM and IRD, and how to optimise the assessment and treatment of one in the presence of the other.
    MeSH term(s) Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/diagnosis ; Fibromyalgia/complications ; Fibromyalgia/diagnosis ; Fibromyalgia/epidemiology ; Humans ; Pain/complications ; Pain Measurement ; Spondylarthritis/complications ; Spondylarthritis/diagnosis
    Language French
    Publishing date 2022-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    DOI 10.53738/REVMED.2022.18.773.477
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