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  1. Book: Ekiteki-kan-kasai-denban-mekanizumu-kenkyū

    Kikuchi, Masao / Sugano, Nobuhiro / Yoda, Shinichi

    (Uchū-Kōkū-Kenkyū-Kaihatsu-Kikō-kenkyū-kaihatsu-hōkoku = JAXA research and development report : RR ; 2006,38)

    2007  

    Title variant Research on flame spread mechanism of fuel droplets
    Author's details Masao Kikuchi; Nobuhiro Sugano; Shinichi Yoda
    Series title Uchū-Kōkū-Kenkyū-Kaihatsu-Kikō-kenkyū-kaihatsu-hōkoku = JAXA research and development report : RR ; 2006,38
    Language Japanese ; English
    Size 19 S., Ill., graph. Darst.
    Publisher Japan Aerospace Exploration Agency
    Publishing place Tōkyō
    Document type Book
    Note Text japan. - Zsfassung in engl. Sprache ; Literaturangaben
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Book: Ekiteki-kan-kaen-denpa-mekanizumu-kenkyū

    Kikuchi, Masao / Yamamoto, Shin / Yoda, Shinichi

    (Uchū-Kōkū-Kenkyū-Kaihatsu-Kikō-kenkyū-kaihatsu-hōkoku = JAXA research and development report : RR ; 2005,26)

    2006  

    Title variant Research on flame spread mechanism of fuel droplets
    Author's details Masao Kikuchi; Shin Yamamoto; Shinichi Yoda
    Series title Uchū-Kōkū-Kenkyū-Kaihatsu-Kikō-kenkyū-kaihatsu-hōkoku = JAXA research and development report : RR ; 2005,26
    Language Japanese ; English
    Size 20 S, Ill., graph. Darst., Tab
    Publisher Japan Aerospace Exploration Agency
    Publishing place Tōkyō
    Document type Book
    Note Text japan. mit engl. Zsfassung ; Literaturangaben
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Article ; Online: Authors response to Management of dialysis patients with hepatitis C virus in the era of direct-acting antiviral therapy.

    Toyoda, Hidenori / Kikuchi, Kan

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

    2023  Volume 28, Issue 1, Page(s) 160–161

    MeSH term(s) Humans ; Antiviral Agents/therapeutic use ; Hepacivirus ; Hepatitis C, Chronic/drug therapy ; Renal Dialysis ; Hepatitis C/drug therapy
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2023-09-28
    Publishing country Australia
    Document type Letter
    ZDB-ID 2119809-3
    ISSN 1744-9987 ; 1091-6660 ; 1744-9979
    ISSN (online) 1744-9987
    ISSN 1091-6660 ; 1744-9979
    DOI 10.1111/1744-9987.14070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: The Impact and Treatment of COVID-19 in Hemodialysis Patients.

    Katagiri, Daisuke / Kikuchi, Kan

    Journal of clinical medicine

    2023  Volume 12, Issue 3

    Abstract: Background: Patients with coronavirus disease 2019 (COVID-19) undergoing maintenance hemodialysis have a poor prognosis and limited treatment options.: Methods: This paper outlines the impact of COVID-19, its treatment, and the efficacy of vaccines ... ...

    Abstract Background: Patients with coronavirus disease 2019 (COVID-19) undergoing maintenance hemodialysis have a poor prognosis and limited treatment options.
    Methods: This paper outlines the impact of COVID-19, its treatment, and the efficacy of vaccines in Japanese patients undergoing hemodialysis with a review of the literature.
    Results: Patients undergoing dialysis in dialysis facilities are at greater risk of exposure to severe acute respiratory syndrome coronavirus 2 than the general population due to limited isolation capabilities. Therefore, vaccines are expected to be effective for patients undergoing dialysis. In addition, effective use of available medications is important because treatment options are limited.
    Conclusions: Efforts should be made to prevent the spread of the infection to high-risk patients undergoing dialysis while ensuring the effective use of vaccines.
    Language English
    Publishing date 2023-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12030838
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Management of dialysis patients with hepatitis C virus in the era of direct-acting antiviral therapy.

    Toyoda, Hidenori / Kikuchi, Kan

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

    2023  Volume 27, Issue 5, Page(s) 831–838

    Abstract: The clinical use of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) infection has dramatically changed management of patients with HCV liver disease since 2014; this is also true for patients undergoing dialysis. Due to the high tolerability ... ...

    Abstract The clinical use of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) infection has dramatically changed management of patients with HCV liver disease since 2014; this is also true for patients undergoing dialysis. Due to the high tolerability and antiviral efficacy of anti-HCV therapy, most dialysis patients with HCV infection should currently be candidates for this treatment. Many patients with HCV antibodies no longer have HCV infection, and it is difficult to identify patients with actual HCV infection based only on HCV antibody assays. Despite the high rate of successful HCV eradication, the risk of liver-related events such as hepatocellular carcinoma (HCC), the major complication of HCV infection, persists even after HCV cure, and patients at risk of HCC should undergo continuous HCC surveillance. Finally, the rarity of HCV reinfection and the survival benefit of HCV eradication in dialysis patients should be explored in further studies.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular ; Antiviral Agents/therapeutic use ; Hepacivirus ; Liver Neoplasms/complications ; Hepatitis C, Chronic/complications ; Hepatitis C, Chronic/drug therapy ; Renal Dialysis/adverse effects ; Hepatitis C/drug therapy ; Hepatitis C/complications
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2023-05-22
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2119809-3
    ISSN 1744-9987 ; 1091-6660 ; 1744-9979
    ISSN (online) 1744-9987
    ISSN 1091-6660 ; 1744-9979
    DOI 10.1111/1744-9987.14003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The Impact and Treatment of COVID-19 in Hemodialysis Patients

    Daisuke Katagiri / Kan Kikuchi

    Journal of Clinical Medicine, Vol 12, Iss 838, p

    2023  Volume 838

    Abstract: Background: Patients with coronavirus disease 2019 (COVID-19) undergoing maintenance hemodialysis have a poor prognosis and limited treatment options. Methods: This paper outlines the impact of COVID-19, its treatment, and the efficacy of vaccines in ... ...

    Abstract Background: Patients with coronavirus disease 2019 (COVID-19) undergoing maintenance hemodialysis have a poor prognosis and limited treatment options. Methods: This paper outlines the impact of COVID-19, its treatment, and the efficacy of vaccines in Japanese patients undergoing hemodialysis with a review of the literature. Results: Patients undergoing dialysis in dialysis facilities are at greater risk of exposure to severe acute respiratory syndrome coronavirus 2 than the general population due to limited isolation capabilities. Therefore, vaccines are expected to be effective for patients undergoing dialysis. In addition, effective use of available medications is important because treatment options are limited. Conclusions: Efforts should be made to prevent the spread of the infection to high-risk patients undergoing dialysis while ensuring the effective use of vaccines.
    Keywords COVID-19 ; hemodialysis ; vaccination ; Medicine ; R
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Treatment of Hepatitis C Virus Infection in Dialysis Patients.

    Kikuchi, Kan

    Contributions to nephrology

    2018  Volume 196, Page(s) 119–122

    Abstract: Since 2014, all-oral, interferon (IFN)-free, direct-acting antiviral (DAA) regimens including daclatasvir + asunaprevir dual regimen, ledipasvir/sofosbuvir combination, ombitasvir/paritaprevir/ritonavir combination, elbasvir + grazoprevir dual regimen, ... ...

    Abstract Since 2014, all-oral, interferon (IFN)-free, direct-acting antiviral (DAA) regimens including daclatasvir + asunaprevir dual regimen, ledipasvir/sofosbuvir combination, ombitasvir/paritaprevir/ritonavir combination, elbasvir + grazoprevir dual regimen, and glecaprevir/pibrentasvir combination have been approved for the treatment of hepatitis C. Studies on DAA regimens reported that DAA therapy causes far fewer adverse reactions compared with IFN therapy and exhibits high efficacy in treating hepatitis C virus (HCV) infection in hemodialysis patients, although the ledipasvir/sofosbuvir combination cannot be used for dialysis patients because sofosbuvir is contraindicated for patients with estimated glomerular filtration rate of <30 mL/min/1.73 m2. Since the safety of DAA therapy in elderly patients has also been confirmed, there is basically no age limit for the use of DAAs. The time has come for any hemodialysis patient to receive effective treatment for curing HCV infection.
    Background: The prevalence of HCV infection among dialysis patients in Japan was as high as 6.2% as of 2015. However, numerous patients are left untreated because of the limited efficacy of and adverse reactions caused by IFN.
    Summary: In Japan, the approval of an all-oral, IFN-free, DAA regimen in 2014 marked a paradigm shift for the treatment of HCV infection in patients with dialysis. DAA therapy causes far fewer adverse reactions compared with IFN therapy and has been reported to be highly effective in treating HCV infection in hemodialysis patients. Key Messages: A remarkable progress in HCV treatment has allowed all patients with chronic hepatitis C to receive effective therapies to cure the disease.
    MeSH term(s) Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Contraindications, Drug ; Drug Therapy, Combination ; Hepatitis C, Chronic/complications ; Hepatitis C, Chronic/drug therapy ; Humans ; Interferons/adverse effects ; Japan ; Renal Dialysis/methods ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/therapy ; Sofosbuvir/adverse effects
    Chemical Substances Antiviral Agents ; Interferons (9008-11-1) ; Sofosbuvir (WJ6CA3ZU8B)
    Language English
    Publishing date 2018-07-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 1662-2782 ; 0302-5144
    ISSN (online) 1662-2782
    ISSN 0302-5144
    DOI 10.1159/000485710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Implementation of two novel schemes for patients on dialysis as a response to the COVID-19 surge in Tokyo.

    Naito, Keisuke / Kikuchi, Kan / Watanabe, Yu / Narita, Tomoyo

    Global health & medicine

    2022  Volume 4, Issue 5, Page(s) 253–258

    Abstract: The Japanese government recommended hospitalization of patients on dialysis once they tested positive because of their high COVID-19 mortality rate and definite need for periodic dialysis. However, after experiencing the Delta variant surge, strategic ... ...

    Abstract The Japanese government recommended hospitalization of patients on dialysis once they tested positive because of their high COVID-19 mortality rate and definite need for periodic dialysis. However, after experiencing the Delta variant surge, strategic changes towards outpatient care for mild or asymptomatic cases, along with strengthening emergency preparedness were needed. Facing the Omicron surge, the Tokyo Metropolitan Government introduced two novel schemes:
    Language English
    Publishing date 2022-04-04
    Publishing country Japan
    Document type Editorial
    ISSN 2434-9194
    ISSN (online) 2434-9194
    DOI 10.35772/ghm.2022.01050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Association of Four Types of Vascular Access Including Arterial Superficialization with Mortality in Maintenance Hemodialysis Patients: A Nationwide Cohort Study in Japan.

    Murakami, Minoru / Fujii, Naohiko / Kanda, Eiichiro / Kikuchi, Kan / Wada, Atsushi / Hamano, Takayuki / Masakane, Ikuto

    American journal of nephrology

    2023  Volume 54, Issue 3-4, Page(s) 83–94

    Abstract: Introduction: Vascular access usage varies widely across countries. Previous studies have evaluated the association of clinical outcomes with the three types of vascular access, namely, arteriovenous fistula (AVF), arteriovenous graft (AVG), and ... ...

    Abstract Introduction: Vascular access usage varies widely across countries. Previous studies have evaluated the association of clinical outcomes with the three types of vascular access, namely, arteriovenous fistula (AVF), arteriovenous graft (AVG), and tunneled and cuffed central venous catheter (TC-CVC). However, little is known regarding the association between arterial superficialization (AS) and the mortality of patients.
    Methods: A nationwide cohort study was conducted using data from the Japanese Society for Dialysis Therapy Renal Data Registry (2006-2007). We included patients aged ≥20 years undergoing hemodialysis with a dialysis vintage ≥6 months. The exposures of interest were the four types of vascular access: AVF, AVG, AS, and TC-CVC. Cox proportional hazard models were used to evaluate the associations of vascular access types with 1-year all-cause and cause-specific mortality.
    Results: A total of 183,490 maintenance hemodialysis patients were included: 90.7% with AVF, 6.9% with AVG, 2.0% with AS, and 0.4% with TC-CVC. During the 1-year follow-up period, 13,798 patients died. Compared to patients with AVF, those with AVG, AS, and TC-CVC had a significantly higher risk of all-cause mortality after adjustment for confounding factors: adjusted hazard ratios (95% confidence intervals) - 1.30 (1.20-1.41), 1.56 (1.39-1.76), and 2.15 (1.77-2.61), respectively. Similar results were obtained for infection-related and cardiovascular mortality.
    Conclusion: This nationwide cohort study conducted in Japan suggested that AVF usage may have the lowest risk of all-cause mortality. The study also suggested that the usage of AS may be associated with better survival rates compared to those of TC-CVC in patients who are not suitable for AVF or AVG.
    MeSH term(s) Humans ; Arteriovenous Shunt, Surgical/adverse effects ; Arteriovenous Shunt, Surgical/methods ; Cohort Studies ; Japan/epidemiology ; Kidney Failure, Chronic/therapy ; Renal Dialysis/adverse effects ; Renal Dialysis/mortality ; Retrospective Studies
    Language English
    Publishing date 2023-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 604540-6
    ISSN 1421-9670 ; 0250-8095
    ISSN (online) 1421-9670
    ISSN 0250-8095
    DOI 10.1159/000529991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1635: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Correction to: Factors associated with SARS-CoV-2 antibody titers and prognosis of breakthrough infection in hemodialysis patients.

    Toda, Masataro / Yoshifuji, Ayumi / Kikuchi, Kan / Koinuma, Masayoshi / Komatsu, Motoaki / Fujii, Kentaro / Kato, Ai / Kikuchi, Takahide / Nakazawa, Atsushi / Ryuzaki, Munekazu

    Clinical and experimental nephrology

    2022  Volume 26, Issue 6, Page(s) 581–582

    Language English
    Publishing date 2022-03-09
    Publishing country Japan
    Document type Published Erratum
    ZDB-ID 1338768-6
    ISSN 1437-7799 ; 1342-1751
    ISSN (online) 1437-7799
    ISSN 1342-1751
    DOI 10.1007/s10157-022-02203-2
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    Zs.A 4922: Show issues Location:
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