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Article: Anatomical risk factors for spermatic cord torsion and their involvement in the choice of orchidopexy technique.

Beaud, Nicolas / Kanbar, Anthony / Abdessater, Maher

Morphologie : bulletin de l'Association des anatomistes

2020 Volume 105, Issue 348, Page(s) 1–9

Abstract: Objective: We aim by this article to present a literature review on the anatomical risk factors for spermatic cord torsion and their involvement the different techniques of orchidopexy.: Materials and methods: The literature review was conducted ... ...

Abstract	Objective: We aim by this article to present a literature review on the anatomical risk factors for spermatic cord torsion and their involvement the different techniques of orchidopexy. Materials and methods: The literature review was conducted following PRISMA check-list, using PubMed database and the Mesh terms: testis, torsion, anomaly, orchidopexy. Techniques of surgical management provided by the EMC (French medico-surgical encyclopedia) were also used. Results: Database research identified 500 articles, and 16 mores articles were added from the review of the references lists of relevant articles. At the end, 42 articles were useful for our review including 6 reviews, 5 cross-sectional studies, 14 cohorts, 10 case reports, 1 meta-analysis, 1 letter, and 5 experimental studies. High insertion of the tunica vaginalis, a long mesorchium, deficient attachment of the epididymis to the testis, and anomalies of the gubernaculum testis are the anatomical predispositions for spermatic cord torsion. After reduction of torsion, many surgical techniques for the fixation of the testis have been suggested including: conventional technique by triangulation with or without fasciotomy, window orchidopexy, scrotal pouch, and vaginal eversion with or without dartos fixation. Conclusion: The most common anatomical factor associated with spermatic cord torsion is the high insertion of the tunica vaginalis. Vaginal eversion with fixation to the dartos might be superior to other known techniques and seems promising to become standard.
MeSH term(s)	Cross-Sectional Studies ; Humans ; Male ; Orchiopexy ; Risk Factors ; Spermatic Cord Torsion/surgery ; Testis
Language	English
Publishing date	2020-09-09
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	1443319-9
ISSN	1286-0115
ISSN	1286-0115
DOI	10.1016/j.morpho.2020.06.006
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Article: Diagnosis and Management of Polyorchidism: A Case Report and Literature Review.

Kanbar, Anthony / Dabal, Charbel / El Khoury, Joey / Halabi, Rami / Assaf, Serge / Mina, Anthony / Breidi, Sabine / Abdessater, Maher / El Khoury, Raghid

Case reports in urology

2023 Volume 2023, Page(s) 1620276

Abstract: Polyorchidism, or supernumerary testis, is a rare congenital abnormality of the genitourinary system. In this paper, we present the case of triorchidism in a seven-year-old asymptomatic child with a suspect left scrotal mass detected on routine physical ... ...

Abstract	Polyorchidism, or supernumerary testis, is a rare congenital abnormality of the genitourinary system. In this paper, we present the case of triorchidism in a seven-year-old asymptomatic child with a suspect left scrotal mass detected on routine physical examination. Imaging studies revealed a third testicle in the left hemiscrotum, with comparable dimensions, signal intensity on MRI, and Doppler flow on ultrasound with the ipsilateral testis. We also discuss the clinical presentations, classifications, and current diagnostic and therapeutic strategies of this condition.
Language	English
Publishing date	2023-06-22
Publishing country	United States
Document type	Case Reports
ZDB-ID	2627659-8
ISSN	2090-6978 ; 2090-696X
ISSN (online)	2090-6978
ISSN	2090-696X
DOI	10.1155/2023/1620276
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Article: Hard flaccid syndrome: state of current knowledge.

Abdessater, Maher / Kanbar, Anthony / Akakpo, William / Beley, Sebastien

Basic and clinical andrology

2020 Volume 30, Page(s) 7

Abstract: Introduction: Hard-flaccid syndrome is gaining increased interest among male sexual dysfunctions in the last years. It is poorly understood and defined. Most of the information comes from online forums. This paper is a review of current knowledge on the ...

Abstract	Introduction: Hard-flaccid syndrome is gaining increased interest among male sexual dysfunctions in the last years. It is poorly understood and defined. Most of the information comes from online forums. This paper is a review of current knowledge on the clinical presentation, diagnosis, pathophysiological mechanisms and treatments of this newly recognized condition. Material and methods: A literature review was conducted on MEDLINE, CENTRAL, PASCAL databases and google scholar, using the terms: hard, flaccid, syndrome. The research identified 16 articles published between 2018 and February 2019. After reference lists review and duplicates removal, 7 full text references were eligible and useful for our review that follows PRISMA guidelines. Results: The condition is acquired, chronic and painful. It is characterized by a constantly semi-rigid penis at the flaccid state and a loss in erectile rigidity. Patients have penile sensory changes, urinary symptoms, erectile dysfunction, pelvic floor muscles contraction and psychological distress. Symptoms are worse in standing position. The majority of the cases aged between their second and third decades. A traumatic injury at the base of an erect penis is the initial event. Neurovascular structures damage and subsequent sensory, muscular and vascular changes follow. Initial symptoms trigger emotional distress and reactional sympathetic stimulation that worsen symptoms. Diagnosis is based on patient's history. Imaging and blood tests are normal. Differential diagnosis includes high-flow priapism and non-erecting erections. A multimodal treatment has been so far the most beneficial strategy, consisting of behavioral modifications to reduce stress and decrease pelvic floor muscles contraction, evaluation and treatment of the associated psychological conditions, and medical therapy for pain control and the treatment of the associated erectile dysfunction. Conclusion: Hard-flaccid syndrome is poorly recognized in the daily clinical experience and not well defined. A multimodal approach seems so far the most efficient strategy for treatment. Additional evidence based studies with better quality are needed to define the exact pathophysiological mechanisms and subsequently more efficient therapeutic strategies.
Language	English
Publishing date	2020-06-04
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2732675-5
ISSN	2051-4190
ISSN	2051-4190
DOI	10.1186/s12610-020-00105-5
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Article: The "Cut-to-the-Light" Technique Laser Endoureterotomy for Complete Ureteral Obstruction Resurfaces! A New Application of an Old Technique.

Yarak, Naim / Zouari, Skander / Karray, Omar / Sleiman, Walid / Abdelwahab, Alaa / Bart, Stéphane / Abdessater, Maher

Research and reports in urology

2022 Volume 14, Page(s) 351–358

Abstract: Objective: To describe our new endoscopic approach in treating iatrogenic ureteral stenosis using the "cut-to-The-light" technique.: Methods: Case of a 54 year-old female patient who underwent a right percutaneous nephrolithotomy to treat a staghorn ... ...

Abstract	Objective: To describe our new endoscopic approach in treating iatrogenic ureteral stenosis using the "cut-to-The-light" technique. Methods: Case of a 54 year-old female patient who underwent a right percutaneous nephrolithotomy to treat a staghorn calculus with two subsequent complimentary ureteroscopies complicated by a severe proximal ureteral obstruction. An antegrade flexible uretereroscope and a retrograde rigid ureteroscope were used to locate the stenosis. With the aid of a 365-µm Ho: YAG laser fiber (settings 0.4 J, 12 Hz), we managed to successfully create a small incision in the stenotic lesion, the rigid ureterscopy light was clearly seen by the antegrade flexible ureteroscope and a through-and-through guidewire was then placed, securing the ureter. Ureteral dilatation was then performed followed by a full thickness incision of the ureteral stenosis. A single 8Fr, 28 cm double J ureteral stent was finally placed after stone fragmentation. Results: The operating time was 200 mins. No blood loss. No fever or signs of UTI were seen shortly after the operation. The Foley catheter was successfully removed at day one post-op. The hospital stay was short of only 2 days. Conclusion: The "cut-to-the-light" technique is a new application in the arsenal of ureteral stricture treatment that has been scarcely described in the literature before. The use of this method seems to offer excellent outcomes thus demonstrating the importance of this minimally invasive technique as an alternative to conventional invasive methods used. We believe that studies with larger samples and longer follow up are needed in order to fully determine the benefits of this method and to assess and reveal its suitable application and its drawbacks.
Language	English
Publishing date	2022-10-10
Publishing country	England
Document type	Case Reports
ZDB-ID	2649530-2
ISSN	2253-2447
ISSN	2253-2447
DOI	10.2147/RRU.S371856
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Article ; Online: Hard flaccid syndrome

Maher Abdessater / Anthony Kanbar / William Akakpo / Sebastien Beley

Basic and Clinical Andrology, Vol 30, Iss 1, Pp 1-

state of current knowledge

2020 Volume 7

Abstract: Résumé Contexte Le syndrome de la détumescence rigide (STR) fait le sujet de plusieurs discussions en ligne concernant les dysfonctions sexuelles. Cette entité est. mal définie et peu reconnue. Nous présentons dans cet article une revue de la littérature ...

Abstract	Résumé Contexte Le syndrome de la détumescence rigide (STR) fait le sujet de plusieurs discussions en ligne concernant les dysfonctions sexuelles. Cette entité est. mal définie et peu reconnue. Nous présentons dans cet article une revue de la littérature sur la présentation clinique, le diagnostic, les mécanismes physiopathologiques et les stratégies de thérapeutique du STR. Matériel et Méthodes La revue de la littérature a été réalisée selon les recommandations PRISMA. En cherchant sur MEDLINE, CENTRAL, PASCAL et google scholar les termes « hard, flaccid et syndrome », on a identifié 16 articles publiés entre 2018 et février 2019. Après la revue des références des articles et le triage des doublons, 7 articles ont été retenus. Résultats Il s’agit d’une pathologie acquise, chronique et douloureuse, caractérisée par une verge semi rigide à l’état flaccide avec une perte de rigidité lors des érections. Les patients souffrent de troubles sensitifs péniens et érectiles avec une contracture permanente des muscles pelviens ainsi que des troubles urinaires et psychologiques. Les symptômes sont aggravés par la position debout. La notion de traumatisme de la base de la verge est. rapportée par la majorité des patients. Ce traumatisme semble entrainer une altération des structures nerveuses et vasculaires péniennes à l’origine des troubles sensitifs et érectiles. Ces derniers créent des troubles émotionnels avec une stimulation sympathique réactionnelle qui engendre une contraction surajoutée des muscles pelviens et qui empire les symptômes. Le diagnostic est. clinique et les examens paracliniques sont normaux. Le traitement est. multimodal, il englobe les thérapies comportementales, la prise en charge des altérations psychologiques et de la douleur, afin d’agir sur la contraction des muscles pelviens et sur le stress associé à la dysfonction érectile. Conclusion Le syndrome de la détumescence rigide reste peu connu et mal défini dans la pratique clinique. Une approche thérapeutique multimodale parait la plus adéquate ...
Keywords	Male sexual dysfunction ; Hard flaccid ; Semi-rigid ; Medicine (General) ; R5-920
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Bilateral laparoscopic ureterolysis using hydrodissection in retroperitoneal fibrosis: a new application of an old technique.

Abdessater, Maher / Elias, Sandra / Boustany, Johnny / El Khoury, Raghid

Research and reports in urology

2019 Volume 11, Page(s) 131–135

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2019-05-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2649530-2
ISSN	2253-2447
ISSN	2253-2447
DOI	10.2147/RRU.S201396
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Article ; Online: La thymoglobuline en traitement d’induction chez les transplantés rénaux à faible risque immunologique: une expérience marocaine.

Abouzid, Zineb / Amar, Mohamed Anass / Abdessater, Maher / Alioubane, Meryem / Benjaafar, Anissa / Ouzeddoun, Naima / Benamar, Loubna / Bayahia, Rabia / Bouattar, Tarik

The Pan African medical journal

2022 Volume 41, Page(s) 138

Abstract: Introduction: Thymoglobulin® is a polyclonal antibody indicated for induction treatment in kidney transplantation. The purpose of this study is to estimate the effectiveness of Thymoglobulin® as induction treatment in kidney transplant patients with low ...

Title translation	Thymoglobulin as induction treatment in kidney transplantants with low immunological risk: a Moroccan experience.
Abstract	Introduction: Thymoglobulin® is a polyclonal antibody indicated for induction treatment in kidney transplantation. The purpose of this study is to estimate the effectiveness of Thymoglobulin® as induction treatment in kidney transplant patients with low immune risk. Methods: we conducted a retrospective study between January 2012 and September 2017. Patients with low immunological risk, defined as the absence of previous transplantation and donor-specific antibodies (DSA), were included and received Thymoglobulin® induction therapy. Demographic and clinical characteristics, biological parameters and post-renal transplant complications were studied. Results: we enrolled 55 kidney transplant patients with an average follow-up period of 38 ± 16 months. The average age of patients was 39,1 ± 12,1 years with a male predominance (58.2%). No patient had DSA prior to transplant. Cumulative dose of Thymoglobulin® was 4,26 ± 0,87 mg/kg, with an average duration of 5 ± 0,82 days. Lymphocyte depletion was maximal on the first day of infusion. Three patients had delayed graft function, at least one episode of bacterial infection in 56,4% of patients, 7 cases of CMV infections (12,7%) and 2 cases of CMV disease (3,6%). Graft survival rate was calculated for all patients with an average serum creatinine of 11,7 ± 3,6 mg/l during the last visit. Conclusion: although it is not indicated for first line treatment in patients with low immunological risk, Thymoglobulin® can nevertheless be prescribed at a lower dose, with similar efficacy and without exposure to a higher risk of rejection.
MeSH term(s)	Antilymphocyte Serum ; Cytomegalovirus Infections/drug therapy ; Female ; Graft Rejection/prevention & control ; Graft Survival ; Humans ; Immunosuppressive Agents/therapeutic use ; Infant, Newborn ; Kidney ; Male ; Retrospective Studies
Chemical Substances	Antilymphocyte Serum ; Immunosuppressive Agents ; thymoglobulin (D7RD81HE4W)
Language	French
Publishing date	2022-02-17
Publishing country	Uganda
Document type	Journal Article
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2022.41.138.23091
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Article: Post orgasmic illness syndrome: what do we know till now?

Abdessater, Maher / Elias, Sandra / Mikhael, Elie / Alhammadi, Abdalla / Beley, Sebastien

Basic and clinical andrology

2019 Volume 29, Page(s) 13

Abstract: Background: Peri orgasmic dysfunctions are very rare and little information exists on their diagnosis and treatment. One of these conditions is post-orgasmic illness syndrome (POIS), manifesting by a debilitating cluster of symptoms affecting men within ...

Abstract	Background: Peri orgasmic dysfunctions are very rare and little information exists on their diagnosis and treatment. One of these conditions is post-orgasmic illness syndrome (POIS), manifesting by a debilitating cluster of symptoms affecting men within seconds, minutes, or hours after ejaculation. The aim of this article is to do a thorough literature review about POIS, in order to elucidate the pathophysiology, the diagnosis and the management of this rare disease. Results: Updated literature review on Pubmed was done, using the following terms: "orgasm illness", "post-orgasmic" and "postorgasmic illness syndrome". The references of the 17 identified publications were also reviewed for additional 8 relevant articles that were all included in the results.POIS has 5 preliminary diagnostic criteria and criterion 1 has 7 described clusters. Pathophysiological hypotheses include: immunological phenomenon (most relevant), opioid-like withdrawal, neuroendocrine response, transient deregulation of the autonomic nervous system, hypersensitivity and disordered cytokines. Differential diagnoses include: chronic prostatitis, orgasmolepsy, benign orgasmic cephalgia, sneezing and rhinorrhea, postcoital dysphoria, post-coital asthma and rhinitis. Patients have been symptomatically treated with antihistamines, non-steroidal anti-inflammatory drugs, selective serotonin reuptake inhibitors, and benzodiazepines. A trial of hyposensitization therapy with autologous semen was successful. Conclusion: POIS is a rare condition that is underdiagnosed, most probably because of its unclear pathophysiology leading to a lack of treatment options. Further studies are warranted to investigate the prevalence, pathophysiology, and management of this debilitating condition.
Language	English
Publishing date	2019-09-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2732675-5
ISSN	2051-4190
ISSN	2051-4190
DOI	10.1186/s12610-019-0093-7
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Article: A Potential Protective Effect of Alcohol Consumption in Male Genital Lichen Sclerosus: A Case-Control Study.

El Khoury, Joey / Andraos, Jessica / Kanbar, Anthony / Halabi, Rami / Assaf, Serge / Mina, Anthony / El Breidi, Sabine / Dabal, Charbel / El Hachem, Charbel / Saad, Rodrigue / Kassis, Antoine / Abdessater, Maher / El Khoury, Raghid

Advances in urology

2023 Volume 2023, Page(s) 7208312

Abstract: Materials and methods: A nested case-control study design was chosen. Subjects enrolled were adult male patients who had a circumcision between January 2010 and December 2020 at our university hospital, with a confirmed LSc diagnosis on pathology. Cases ...

Abstract	Materials and methods: A nested case-control study design was chosen. Subjects enrolled were adult male patients who had a circumcision between January 2010 and December 2020 at our university hospital, with a confirmed LSc diagnosis on pathology. Cases were matched with controls by age with a ratio of 1 : 1, all of whom were circumcised and had a negative pathology report. Data collection consisted of sociodemographic, behavioral, and past medical and familial history characteristics. Results: A total of 94 patients were enrolled. The mean age was 49.81 (±22.92) in the group of men with LSc. No significant differences in sociodemographic characteristics (age and BMI) were found between the two compared groups. Smoking cannot predict LSc as opposed to alcohol consumption, which we found to be a protective factor against the appearance of LSc ( Conclusion: In this study, we were able to compare multiple variables between 47 circumcised patients diagnosed with LSc and a control group. We found that LSc patients showed higher rates of diabetes and hypertension. A potential protective effect of alcohol consumption is to be explored in future projects with bigger sample sizes and higher statistical powers.
Language	English
Publishing date	2023-03-15
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2397564-7
ISSN	1687-6377 ; 1687-6369
ISSN (online)	1687-6377
ISSN	1687-6369
DOI	10.1155/2023/7208312
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Article ; Online: Recurrent metastatic clear cell renal carcinoma with sarcomatoid dedifferentiation treated with surgery and Cabozantinib.

Boustany, Johnny / Abdessater, Maher / Hachem, Charbel El / Khoury, Ziad El / Khoury, Walid El / Khoury, Raghid El

Oncotarget

2020 Volume 11, Issue 20, Page(s) 1922–1928

Abstract: Renal cell carcinoma with sarcomatoid dedifferentiation is an entity of RCC that has undergone an anaplastic transformation with both a carcinomatous and a sarcomatous component. The standard treatment in metastatic patients is immunotherapy. The aim of ... ...

Abstract	Renal cell carcinoma with sarcomatoid dedifferentiation is an entity of RCC that has undergone an anaplastic transformation with both a carcinomatous and a sarcomatous component. The standard treatment in metastatic patients is immunotherapy. The aim of this article is to describe our case of metastatic recurrent RCC with sarcomatoid dedifferentiation in a 59 year old male patient treated with nephrectomy and multiple metastasectomies followed by Cabozantinib. Consecutive PET-CT scans showed no evidence of recurrence, three years after the last metastasectomy, and the patient is having currently a normal life. Sarcomatoid dedifferentiation remains a poor prognosis factor in RCC. Surgery for metastases followed by Cabozantinib may be a therapeutic option in metastatic young patients. However, a prospective randomized trial would be the best option to validate this approach.
Language	English
Publishing date	2020-05-19
Publishing country	United States
Document type	Case Reports
ZDB-ID	2560162-3
ISSN	1949-2553 ; 1949-2553
ISSN (online)	1949-2553
ISSN	1949-2553
DOI	10.18632/oncotarget.27543
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