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  1. Article ; Online: Phytochemical, Histochemical and

    Shaikh, Sana Saffiruddin / Bawazir, Abubakar Salam / Yahya, Barrawaz Aateka

    Turkish journal of pharmaceutical sciences

    2022  Volume 19, Issue 2, Page(s) 145–152

    Abstract: Objectives: Costaceae family comprises many ornamental and medicinal plants used for different diseases. This investigation includes the phytochemical, histochemical, and : Materials and methods: Solvents such as methanol, ethyl acetate, and hexane ... ...

    Abstract Objectives: Costaceae family comprises many ornamental and medicinal plants used for different diseases. This investigation includes the phytochemical, histochemical, and
    Materials and methods: Solvents such as methanol, ethyl acetate, and hexane were used to extract the leaves and rhizomes of both plants. The antibacterial study was executed using the agar well diffusion technique.
    Results: Phytochemical study confirmed that alkaloids, flavonoids, quinones, and saponins were present in solvent extracts of both plants. The macromorphological studies including size, shape, texture, surface characters, and color, were analyzed.
    Conclusion: Histochemical analysis revealed alkaloids, proteins, and phenols in the vascular bundles, the cortex, and epidermis of stem, root, and leaves of the plants. Inhibition zones caused by the methanol and hexane extracts showed better antibacterial activity compared to those of other extracts. Future work on the isolation, purification, and characterization of the active constituents and the elucidation of possible mechanisms can be executed.
    Language English
    Publishing date 2022-05-05
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2238484-4
    ISSN 2148-6247 ; 2148-6247
    ISSN (online) 2148-6247
    ISSN 2148-6247
    DOI 10.4274/tjps.galenos.2021.02058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Recent advancements on hyperthermia driven controlled drug delivery from nanotherapeutics.

    Baig, Mirza Shahed / Haque, M Akiful / Konatham, Teja Kumar Reddy / Mohammad, Badrud Duza / Yahya, Barrawaz Aateka / Saffiruddin, Shaikh Sana / Siddiqui, Falak A / Khan, Sharuk L

    Recent advances in drug delivery and formulation

    2022  

    Abstract: Previous reviews of the works on magnetic nanoparticles for hyperthermia induced treatment concentrated mostly on magnetic fluid hyperthermia (MFH) employing monometallic/metal oxide nanocomposites. In the literature, the word "hyperthermia" was also ... ...

    Abstract Previous reviews of the works on magnetic nanoparticles for hyperthermia induced treatment concentrated mostly on magnetic fluid hyperthermia (MFH) employing monometallic/metal oxide nanocomposites. In the literature, the word "hyperthermia" was also limited to the use of heat for medicinal purposes. A number of publications have recently been published demonstrating that magnetic nanoparticle-based hyperthermia may produce restricted high temperatures, resulting in the release of medicines that are either connected to the magnetic nanoparticles or encased in polymer matrices. In this debate, we propose broadening the concept of "hyperthermia" to encompass temperature-based treatment as well as magnetically controlled medication delivery. The review also addresses core-shell magnetic nanomaterials, particularly nanoshells made by stacked assembly, for the use of hyperthermia-based treatment and precise administration of drugs. The primary objective of this review article is to demonstrate how the combination of hyperthermia-induced therapy and 'on demand' drug release models may lead to effective applications in personalized medicine.
    Language English
    Publishing date 2022-09-02
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2667-3886
    ISSN (online) 2667-3886
    DOI 10.2174/2667387816666220902091043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19 pandemic crisis-a complete outline of SARS-CoV-2.

    Shaikh, Sana Saffiruddin / Jose, Anooja P / Nerkar, Disha Anil / Vijaykumar Kv, Midhuna / Shaikh, Saquib Khaleel

    Future journal of pharmaceutical sciences

    2020  Volume 6, Issue 1, Page(s) 116

    Abstract: Background: Coronavirus (SARS-CoV-2), the cause of COVID-19, a fatal disease emerged from Wuhan, a large city in the Chinese province of Hubei in December 2019.: Main body of abstract: The World Health Organization declared COVID-19 as a pandemic due ...

    Abstract Background: Coronavirus (SARS-CoV-2), the cause of COVID-19, a fatal disease emerged from Wuhan, a large city in the Chinese province of Hubei in December 2019.
    Main body of abstract: The World Health Organization declared COVID-19 as a pandemic due to its spread to other countries inside and outside Asia. Initial confirmation of the pandemic shows patient exposure to the Huanan seafood market. Bats might be a significant host for the spread of coronaviruses via an unknown intermediate host. The human-to-human transfer has become a significant concern due to one of the significant reasons that is asymptomatic carriers or silent spreaders. No data is obtained regarding prophylactic treatment for COVID-19, although many clinical trials are underway.
    Conclusion: The most effective weapon is prevention and precaution to avoid the spread of the pandemic. In this current review, we outline pathogenesis, diagnosis, treatment, ongoing clinical trials, prevention, and precautions. We have also highlighted the impact of pandemic worldwide and challenges that can help to overcome the fatal disease in the future.
    Keywords covid19
    Language English
    Publishing date 2020-11-17
    Publishing country Egypt
    Document type Journal Article ; Review
    ZDB-ID 2834845-X
    ISSN 2314-7253 ; 2314-7253
    ISSN (online) 2314-7253
    ISSN 2314-7253
    DOI 10.1186/s43094-020-00133-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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