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  1. Article ; Online: Response to the letter by Dr. Naoya Yamada, and Dr. Koichi Mizuta regarding our manuscript: "Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis".

    Shirabe, Ken / Bekki, Yuki / Gantumur, Dolgormaa / Araki, Kenichiro / Ishii, Norihiro / Kuno, Atsushi / Narimatsu, Hisashi / Mizokami, Masashi

    Journal of gastroenterology

    2018  Volume 54, Issue 2, Page(s) 206–207

    MeSH term(s) Antigens, Neoplasm ; Humans ; Liver Cirrhosis ; Polysaccharides
    Chemical Substances Antigens, Neoplasm ; Polysaccharides
    Language English
    Publishing date 2018-11-09
    Publishing country Japan
    Document type Letter ; Comment
    ZDB-ID 1186495-3
    ISSN 1435-5922 ; 0944-1174
    ISSN (online) 1435-5922
    ISSN 0944-1174
    DOI 10.1007/s00535-018-1524-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 620: Show issues Location:
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  2. Article: Trailblazing through the Opioid Epidemic. Will Science Prevail?

    Limratana, Panop / Yuki, Koichi

    Translational perioperative and pain medicine

    2023  Volume 10, Issue 2, Page(s) 530–532

    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Journal Article
    ISSN 2330-4871
    ISSN 2330-4871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Role of General Anesthetic Drug Selection in Cancer Outcome.

    Yuki, Koichi

    BioMed research international

    2021  Volume 2021, Page(s) 2563093

    Abstract: Cancer remains to be the leading cause of death globally. Surgery is a mainstay treatment for solid tumors. Thus, it is critical to optimize perioperative care. Anesthesia is a requisite component for surgical tumor resection, and general anesthesia is ... ...

    Abstract Cancer remains to be the leading cause of death globally. Surgery is a mainstay treatment for solid tumors. Thus, it is critical to optimize perioperative care. Anesthesia is a requisite component for surgical tumor resection, and general anesthesia is given in the vast majority of tumor resection cases. Because anesthetics are growingly recognized as immunomodulators, it is critical to optimize anesthetic regimens for cancer surgery if the selection can affect outcomes. Here, we reviewed the role of volatile and intravenous anesthesia used for cancer surgery in cancer recurrence.
    MeSH term(s) Anesthesia, General ; Anesthetics/pharmacology ; Animals ; Humans ; Neoplasm Recurrence, Local/pathology ; Neoplasms/immunology ; Neoplasms/pathology ; Neoplasms/surgery ; T-Lymphocytes/immunology ; Treatment Outcome
    Chemical Substances Anesthetics
    Language English
    Publishing date 2021-10-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2021/2563093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Role of General Anesthetic Drug Selection in Cancer Outcome

    Koichi Yuki

    BioMed Research International, Vol

    2021  Volume 2021

    Abstract: Cancer remains to be the leading cause of death globally. Surgery is a mainstay treatment for solid tumors. Thus, it is critical to optimize perioperative care. Anesthesia is a requisite component for surgical tumor resection, and general anesthesia is ... ...

    Abstract Cancer remains to be the leading cause of death globally. Surgery is a mainstay treatment for solid tumors. Thus, it is critical to optimize perioperative care. Anesthesia is a requisite component for surgical tumor resection, and general anesthesia is given in the vast majority of tumor resection cases. Because anesthetics are growingly recognized as immunomodulators, it is critical to optimize anesthetic regimens for cancer surgery if the selection can affect outcomes. Here, we reviewed the role of volatile and intravenous anesthesia used for cancer surgery in cancer recurrence.
    Keywords Medicine ; R
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: The immunomodulatory mechanism of dexmedetomidine.

    Yuki, Koichi

    International immunopharmacology

    2021  Volume 97, Page(s) 107709

    Abstract: Dexmedetomidine has been increasingly introduced into the perioperative care of surgical patients. Because a subset of anesthetics/sedatives are immunomodulatory, it is critical to understand the role of dexmedetomidine in our host immune functions. Here ...

    Abstract Dexmedetomidine has been increasingly introduced into the perioperative care of surgical patients. Because a subset of anesthetics/sedatives are immunomodulatory, it is critical to understand the role of dexmedetomidine in our host immune functions. Here we reviewed the role of dexmedetomidine in different immune cells. We also reviewed published clinical articles that described the role of dexmedetomidine in organ injury, cancer surgery, and infection. In animal studies, dexmedetomidine attenuated organ injury. In clinical studies, dexmedetomidine was associated with an improvement in outcomes in cardiac surgery and transplant surgery. However, there is a paucity in research examining how dexmedetomidine is associated with these outcomes. Further studies are needed to understand its clinical application from immunological standpoints.
    MeSH term(s) Adrenergic alpha-2 Receptor Agonists/pharmacology ; Adrenergic alpha-2 Receptor Agonists/therapeutic use ; Animals ; Dexmedetomidine/pharmacology ; Dexmedetomidine/therapeutic use ; Disease Models, Animal ; Humans ; Immunologic Factors/pharmacology ; Immunologic Factors/therapeutic use ; Inflammation Mediators/antagonists & inhibitors ; Inflammation Mediators/metabolism ; Leukocytes/drug effects ; Leukocytes/immunology ; Leukocytes/metabolism ; Perioperative Period ; Receptors, Adrenergic, alpha-2/metabolism ; Stress, Physiological/drug effects ; Stress, Physiological/immunology ; Surgical Procedures, Operative/adverse effects
    Chemical Substances Adrenergic alpha-2 Receptor Agonists ; Immunologic Factors ; Inflammation Mediators ; Receptors, Adrenergic, alpha-2 ; Dexmedetomidine (67VB76HONO)
    Language English
    Publishing date 2021-04-29
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2021.107709
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5408: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article: Immediate lymphatic reconstruction for breast cancer-related lymphedema: current status and challenges.

    Otsuki, Yuki / Nuri, Takashi / Ueda, Koichi

    Gland surgery

    2024  Volume 13, Issue 3, Page(s) 455–457

    Language English
    Publishing date 2024-03-20
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 3016969-0
    ISSN 2227-8575 ; 2227-684X
    ISSN (online) 2227-8575
    ISSN 2227-684X
    DOI 10.21037/gs-23-527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A Skewered Flap Technique for Fat Grafting in Abdominal Flap Breast Reconstruction.

    Otsuki, Yuki / Nuri, Takashi / Ichida, Tatsuya / Ueda, Koichi

    Plastic and reconstructive surgery. Global open

    2024  Volume 12, Issue 4, Page(s) e5762

    Language English
    Publishing date 2024-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7091: Show issues Location:
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  8. Article: Anesthetic Management for Heart Transplantation in Adults with Congenital Heart Disease.

    Yuki, Koichi

    Translational perioperative and pain medicine

    2020  Volume 7, Issue 3, Page(s) 248–252

    Abstract: As the outcome of patients with congenital heart disease (CHD) has improved, the number of adults with congenital heart disease (ACHD) outnumbered pediatric population with CHD. Heart failure is responsible for 40% of mortality among ACHD, and the number ...

    Abstract As the outcome of patients with congenital heart disease (CHD) has improved, the number of adults with congenital heart disease (ACHD) outnumbered pediatric population with CHD. Heart failure is responsible for 40% of mortality among ACHD, and the number of heart transplantation for ACHD is gradually increasing. However, the early mortality rate of heart transplantation is significantly higher in ACHD than in non-ACHD. Understanding the unique characteristics of heart transplantation in ACHD is critical. In contrast to their early outcome their long-term survival is better in ACHD than in non-CHD patients, and they are likely to present to anesthesia care after heart transplantation for various reasons. Understanding specific issues in post-transplant anesthesia care is another important aspect.
    Language English
    Publishing date 2020-03-27
    Publishing country United States
    Document type Journal Article
    ISSN 2330-4871
    ISSN 2330-4871
    DOI 10.31480/2330-4871/120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: CD11a regulates hematopoietic stem and progenitor cells.

    Hou, Lifei / Yuki, Koichi

    Frontiers in immunology

    2023  Volume 14, Page(s) 1219953

    Abstract: Integrin αLβ2 (CD11a/CD18, CD11a) is a critical leukocyte adhesion molecule in leukocyte arrest and immunological synapse formation. However, its role in the bone marrow has not been investigated in depth. Here we showed that CD11a was expressed on all ... ...

    Abstract Integrin αLβ2 (CD11a/CD18, CD11a) is a critical leukocyte adhesion molecule in leukocyte arrest and immunological synapse formation. However, its role in the bone marrow has not been investigated in depth. Here we showed that CD11a was expressed on all subsets of hematopoietic stem and progenitor cells (HPSCs). CD11a deficiency enhanced HSPCs activity under lipopolysaccharide (LPS) stimulation as demonstrated by a higher HSPC cell count along with an increase in cell proliferation. However, our mixed chimera experiment did not support that this phenotype was driven in a cell-intrinsic manner. Rather we found that the production of IL-27, a major cytokine that drives HSPC proliferation, was significantly upregulated both
    MeSH term(s) Hematopoietic Stem Cells ; Cell Adhesion Molecules ; Lymphocyte Function-Associated Antigen-1 ; Bone Marrow ; CD11a Antigen
    Chemical Substances Cell Adhesion Molecules ; Lymphocyte Function-Associated Antigen-1 ; CD11a Antigen
    Language English
    Publishing date 2023-09-14
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1219953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Narrative review of systemic inflammatory response mechanisms in cardiac surgery and immunomodulatory role of anesthetic agents.

    Maisat, Wiriya / Yuki, Koichi

    Annals of cardiac anaesthesia

    2023  Volume 26, Issue 2, Page(s) 133–142

    Abstract: Although surgical techniques and perioperative care have made significant advances, perioperative mortality in cardiac surgery remains relatively high. Single- or multiple-organ failure remains the leading cause of postoperative mortality. Systemic ... ...

    Abstract Although surgical techniques and perioperative care have made significant advances, perioperative mortality in cardiac surgery remains relatively high. Single- or multiple-organ failure remains the leading cause of postoperative mortality. Systemic inflammatory response syndrome (SIRS) is a common trigger for organ injury or dysfunction in surgical patients. Cardiac surgery involves major surgical dissection, the use of cardiopulmonary bypass (CPB), and frequent blood transfusions. Ischemia-reperfusion injury and contact activation from CPB are among the major triggers for SIRS. Blood transfusion can also induce proinflammatory responses. Here, we review the immunological mechanisms of organ injury and the role of anesthetic regimens in cardiac surgery.
    MeSH term(s) Humans ; Cardiac Surgical Procedures/methods ; Cardiopulmonary Bypass/adverse effects ; Cardiopulmonary Bypass/methods ; Systemic Inflammatory Response Syndrome ; Blood Transfusion
    Language English
    Publishing date 2023-09-14
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    DOI 10.4103/aca.aca_147_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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