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  1. Article ; Online: Comorbidities in idiopathic inflammatory myopathies: Data from the MyoCite cohort.

    Conticini, Edoardo / Khursheed, Tayyeba / Anuja, Anamika Kumari / Agarwal, Vikas / Gupta, Latika

    International journal of rheumatic diseases

    2023  Volume 27, Issue 1, Page(s) e14995

    MeSH term(s) Humans ; Myositis/diagnosis ; Myositis/epidemiology ; Dermatomyositis ; Comorbidity
    Language English
    Publishing date 2023-12-07
    Publishing country England
    Document type Letter
    ZDB-ID 2426924-4
    ISSN 1756-185X ; 1756-1841
    ISSN (online) 1756-185X
    ISSN 1756-1841
    DOI 10.1111/1756-185X.14995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Role of Major Salivary Gland Ultrasound in the Diagnostic Workup of Sicca Syndrome: A Large Single-Centre Study.

    Vallifuoco, Giulia / Falsetti, Paolo / Bardelli, Marco / Conticini, Edoardo / Gentileschi, Stefano / Baldi, Caterina / Al Khayyat, Suhel Gabriele / Cantarini, Luca / Frediani, Bruno

    Tomography (Ann Arbor, Mich.)

    2024  Volume 10, Issue 1, Page(s) 66–78

    Abstract: 1) Objective: To determine the diagnostic accuracy of major salivary gland ultrasonography (SGUS) in primary Sjogren's syndrome (SS), we used the Outcome Measures in Rheumatology Clinical Trials (OMERACT) scoring system on a large single-centre cohort ... ...

    Abstract (1) Objective: To determine the diagnostic accuracy of major salivary gland ultrasonography (SGUS) in primary Sjogren's syndrome (SS), we used the Outcome Measures in Rheumatology Clinical Trials (OMERACT) scoring system on a large single-centre cohort of patients with sicca syndrome. (2) Method: We retrospectively collected the clinical, imaging and serological data of all the patients referred with a suspicion of SS who underwent SGUS and minor salivary glands biopsy. (3) Results: A total of 132 patients were included. The SGUS scores were correlated between the two sides (
    MeSH term(s) Humans ; Sjogren's Syndrome/diagnostic imaging ; Retrospective Studies ; Salivary Glands/diagnostic imaging ; Ultrasonography ; Fibrosis
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2379-139X
    ISSN (online) 2379-139X
    DOI 10.3390/tomography10010006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Idiopathic inflammatory myopathies: one year in review 2023.

    Conticini, Edoardo / Dourado, Eduardo / Bottazzi, Francesca / Cardelli, Chiara / Bruno, Lorenza / Schmidt, Jens / Carli, Linda / Cavagna, Lorenzo / Barsotti, Simone

    Clinical and experimental rheumatology

    2024  Volume 42, Issue 2, Page(s) 213–224

    Abstract: Idiopathic inflammatory myopathies are a group of rare, autoimmune, diseases typically involving striate muscle and also variously affecting several other systems or organs, such as joints, skin, lungs, heart and gastrointestinal tract. IIM are mainly ... ...

    Abstract Idiopathic inflammatory myopathies are a group of rare, autoimmune, diseases typically involving striate muscle and also variously affecting several other systems or organs, such as joints, skin, lungs, heart and gastrointestinal tract. IIM are mainly characterised by subacute onset and chronic course and are burdened by significant morbidity and mortality. Despite the rarity of these conditions, several efforts have been undertaken in the last years to better understand their pathogenesis, as well as to achieve a more precise classification and to define the optimal therapeutic approach. The aim of this review is to provide an up-to-date digest of the most relevant studies published on this topic over the last year.
    MeSH term(s) Humans ; Myositis/diagnosis ; Myositis/drug therapy ; Autoimmune Diseases/diagnosis ; Autoimmune Diseases/therapy
    Language English
    Publishing date 2024-03-14
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    DOI 10.55563/clinexprheumatol/dh5o6c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Idiopathic inflammatory myopathies: one year in review 2022.

    Dourado, Eduardo / Bottazzi, Francesca / Cardelli, Chiara / Conticini, Edoardo / Schmidt, Jens / Cavagna, Lorenzo / Barsotti, Simone

    Clinical and experimental rheumatology

    2023  Volume 41, Issue 2, Page(s) 199–213

    Abstract: Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disorders in which chronic inflammation of the skeletal muscle, leading to muscle weakness, is a common feature. Different phenotypes have been identified within the IIM spectrum based ...

    Abstract Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disorders in which chronic inflammation of the skeletal muscle, leading to muscle weakness, is a common feature. Different phenotypes have been identified within the IIM spectrum based on extra-muscular manifestations, immunology, muscle histology, responsiveness to therapy, and prognosis. The pathogenesis, classification, treatment, and prognosis of the different IIM subtypes are subject to active discussion and research. This review highlights the most relevant literature published on this topic over the last year.
    MeSH term(s) Humans ; Myositis ; Muscle, Skeletal/pathology ; Prognosis ; Inflammation/pathology
    Language English
    Publishing date 2023-02-15
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    DOI 10.55563/clinexprheumatol/jof6qn
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Decrease in life expectancy due to COVID-19 disease not offset by reduced environmental impacts associated with lockdowns in Italy.

    Rugani, Benedetto / Conticini, Edoardo / Frediani, Bruno / Caro, Dario

    Environmental pollution (Barking, Essex : 1987)

    2021  Volume 292, Issue Pt A, Page(s) 118224

    Abstract: The consequence of the lockdowns implemented to address the COVID-19 pandemic on human health damage due to air pollution and other environmental issues must be better understood. This paper analyses the effect of reducing energy demand on the evolution ... ...

    Abstract The consequence of the lockdowns implemented to address the COVID-19 pandemic on human health damage due to air pollution and other environmental issues must be better understood. This paper analyses the effect of reducing energy demand on the evolution of environmental impacts during the occurrence of 2020-lockdown periods in Italy, with a specific focus on life expectancy. An energy metabolism analysis is conducted based on the life cycle assessment (LCA) of all monthly energy consumptions, by sector, category and province area in Italy between January 2015 to December 2020. Results show a general decrease (by ∼5% on average) of the LCA midpoint impact categories (global warming, stratospheric ozone depletion, fine particulate matter formation, etc.) over the entire year 2020 when compared to past years. These avoided impacts, mainly due to reductions in fossil energy consumptions, are meaningful during the first lockdown phase between March and May 2020 (by ∼21% on average). Regarding the LCA endpoint damage on human health, ∼66 Disability Adjusted Life Years (DALYs) per 100,000 inhabitants are estimated to be saved. The analysis shows that the magnitude of the officially recorded casualties is substantially larger than the estimated gains in human lives due to the environmental impact reductions. Future research could therefore investigate the complex cause-effect relationships between the deaths occurred in 2020 imputed to COVID-19 disease and co-factors other than the SARS-CoV-2 virus.
    MeSH term(s) Air Pollutants/analysis ; Air Pollution/analysis ; COVID-19 ; Communicable Disease Control ; Environment ; Environmental Monitoring ; Humans ; Italy ; Life Expectancy ; Pandemics ; Particulate Matter/analysis ; SARS-CoV-2
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2021-09-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2021.118224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Superb microvascular imaging in giant cell arteritis.

    Conticini, Edoardo / Falsetti, Paolo / Baldi, Caterina / Bardelli, Marco / Cantarini, Luca / Frediani, Bruno

    Clinical and experimental rheumatology

    2022  Volume 40, Issue 4, Page(s) 860–861

    MeSH term(s) Diagnostic Imaging ; Giant Cell Arteritis/diagnostic imaging ; Humans
    Language English
    Publishing date 2022-04-27
    Publishing country Italy
    Document type Letter ; Comment
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    DOI 10.55563/clinexprheumatol/ygcvaz
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Routine color doppler ultrasonography for the early diagnosis of cranial giant cell arteritis relapses.

    Conticini, Edoardo / Falsetti, Paolo / Baldi, Caterina / Fabiani, Claudia / Cantarini, Luca / Frediani, Bruno

    Internal and emergency medicine

    2022  Volume 17, Issue 8, Page(s) 2431–2435

    MeSH term(s) Humans ; Giant Cell Arteritis/diagnostic imaging ; Ultrasonography, Doppler, Color ; Recurrence ; Early Diagnosis ; Ultrasonography
    Language English
    Publishing date 2022-09-26
    Publishing country Italy
    Document type Letter
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-022-03110-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Decrease in life expectancy due to COVID-19 disease not offset by reduced environmental impacts associated with lockdowns in Italy

    Rugani, Benedetto / Conticini, Edoardo / Frediani, Bruno / Caro, Dario

    Environmental pollution. 2022 Jan. 01, v. 292

    2022  

    Abstract: The consequence of the lockdowns implemented to address the COVID-19 pandemic on human health damage due to air pollution and other environmental issues must be better understood. This paper analyses the effect of reducing energy demand on the evolution ... ...

    Abstract The consequence of the lockdowns implemented to address the COVID-19 pandemic on human health damage due to air pollution and other environmental issues must be better understood. This paper analyses the effect of reducing energy demand on the evolution of environmental impacts during the occurrence of 2020-lockdown periods in Italy, with a specific focus on life expectancy. An energy metabolism analysis is conducted based on the life cycle assessment (LCA) of all monthly energy consumptions, by sector, category and province area in Italy between January 2015 to December 2020. Results show a general decrease (by ∼5% on average) of the LCA midpoint impact categories (global warming, stratospheric ozone depletion, fine particulate matter formation, etc.) over the entire year 2020 when compared to past years. These avoided impacts, mainly due to reductions in fossil energy consumptions, are meaningful during the first lockdown phase between March and May 2020 (by ∼21% on average). Regarding the LCA endpoint damage on human health, ∼66 Disability Adjusted Life Years (DALYs) per 100,000 inhabitants are estimated to be saved. The analysis shows that the magnitude of the officially recorded casualties is substantially larger than the estimated gains in human lives due to the environmental impact reductions. Future research could therefore investigate the complex cause-effect relationships between the deaths occurred in 2020 imputed to COVID-19 disease and co-factors other than the SARS-CoV-2 virus.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; air pollution ; energy ; energy metabolism ; environmental impact ; evolution ; fossil fuels ; human health ; humans ; life cycle assessment ; longevity ; ozone depletion ; particulates ; stratosphere ; viruses ; Italy
    Language English
    Dates of publication 2022-0101
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2021.118224
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Atypical Posterior Reversible Encephalopathy Syndrome (PRES) in a Patient with Polymyalgia Rheumatica and Giant Cell Arteritis.

    Falsetti, Paolo / Acciai, Caterina / Conticini, Edoardo / Cantarini, Luca / Frediani, Bruno

    Current health sciences journal

    2021  Volume 47, Issue 2, Page(s) 306–309

    Abstract: Posterior reversible encephalopathy syndrome (PRES) is a potentially life-threatening condition, composed of focal neurologic symptoms and peculiar magnetic resonance imaging (MRI) findings suggestive for cerebral vasogenic edema. PRES has been ... ...

    Abstract Posterior reversible encephalopathy syndrome (PRES) is a potentially life-threatening condition, composed of focal neurologic symptoms and peculiar magnetic resonance imaging (MRI) findings suggestive for cerebral vasogenic edema. PRES has been predominantly associated with severe hypertension, but a concomitant inflammatory state, common in vasculitis, can contribute to worsening cerebral vasogenic edema towards cytotoxic edema, and it should be promptly treated with glucocorticoids (GC). Atypical cases of PRES should be suspected in cases of focal neurologic symptoms, associated with severe hypertension, and systemic inflammation. We report the first description of a patient with polymyalgia rheumatica and giant cell arteritis who developed PRES after GC discontinuation for arthroscopic surgery.
    Language English
    Publishing date 2021-06-30
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.47.02.23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Giant cell arteritis presenting as a stroke in the internal carotid artery territory: a case-based review.

    Conticini, Edoardo / Falsetti, Paolo / Bardelli, Marco / Cantarini, Luca / Frediani, Bruno

    Reumatologia

    2021  Volume 59, Issue 2, Page(s) 121–125

    Abstract: Giant cell arteritis (GCA) is a large-vessel vasculitis, typically affecting the aorta and its branches. The involvement of vertebral and internal carotid arteries occurs in a limited number of cases, and stroke as a presenting symptom of GCA is ... ...

    Abstract Giant cell arteritis (GCA) is a large-vessel vasculitis, typically affecting the aorta and its branches. The involvement of vertebral and internal carotid arteries occurs in a limited number of cases, and stroke as a presenting symptom of GCA is extremely unusual: this subset of the disease has a poor prognosis and rarely responds to immunosuppression. We report the case of a 70-year-old woman, who presented to the Emergency Department for ischemic stroke, which appeared to be the first and only symptom of GCA. The prompt administration of steroids and tocilizumab (TCZ) led to clinical and radiological resolution, with no residual disability at 6-month follow-up. Our case-based review, highlighting the rarity of a large vessel vasculitis presenting only with a cerebrovascular accident, provides new evidence for the efficacy of TCZ even in more unusual varieties of GCA: in these cases, TCZ should be immediately prescribed, in order to prevent mortality and severe long-term morbidity.
    Language English
    Publishing date 2021-04-27
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 604151-6
    ISSN 0034-6233
    ISSN 0034-6233
    DOI 10.5114/reum.2021.105414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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