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  1. Article ; Online: Dampening Logistics Creating Inequitable Access: A Major Threat Despite Advancements.

    Ayoobkhan, Fathima Shehnaz / Abdallah, Al-Ola / Anwer, Faiz / Ahmed, Nausheen

    Clinical lymphoma, myeloma & leukemia

    2024  

    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2540992-X
    ISSN 2152-2669 ; 2152-2650
    ISSN (online) 2152-2669
    ISSN 2152-2650
    DOI 10.1016/j.clml.2024.02.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5903: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Real-world CAR-T findings for large B-cell lymphoma from a single institution experience.

    Lutfi, Forat / Tun, Aung M / Hoffmann, Marc / Ahmed, Nausheen

    Annals of palliative medicine

    2024  

    Language English
    Publishing date 2024-04-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2828544-X
    ISSN 2224-5839 ; 2224-5839
    ISSN (online) 2224-5839
    ISSN 2224-5839
    DOI 10.21037/apm-23-545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Bridging the Gap: Early Transition and Hybrid Models of Care to Improve Access to Chimeric Antigen Receptor T Cell Therapy.

    Ahmed, Nausheen / Mahmoudjafari, Zahra / Hamadani, Mehdi / Hashmi, Hamza

    Transplantation and cellular therapy

    2023  Volume 29, Issue 6, Page(s) 399–402

    MeSH term(s) Receptors, Chimeric Antigen/genetics ; Receptors, Chimeric Antigen/therapeutic use ; Immunotherapy, Adoptive ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/therapeutic use ; Cell- and Tissue-Based Therapy
    Chemical Substances Receptors, Chimeric Antigen ; Receptors, Antigen, T-Cell
    Language English
    Publishing date 2023-03-27
    Publishing country United States
    Document type Letter
    ZDB-ID 3062231-1
    ISSN 2666-6367
    ISSN (online) 2666-6367
    DOI 10.1016/j.jtct.2023.03.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5082: Show issues Location:
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  4. Article ; Online: Dawn of Hope for Improved Access to BCMA Therapy: Chimeric Antigen Receptor T Cell and Bispecific Products.

    Ahmed, Nausheen / Wesson, William / Abdallah, Al-Ola

    Transplantation and cellular therapy

    2023  Volume 29, Issue 7, Page(s) 474–475

    MeSH term(s) Humans ; Receptors, Chimeric Antigen ; T-Lymphocytes ; B-Cell Maturation Antigen ; Immunotherapy, Adoptive ; Multiple Myeloma
    Chemical Substances Receptors, Chimeric Antigen ; B-Cell Maturation Antigen
    Language English
    Publishing date 2023-04-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 3062231-1
    ISSN 2666-6367
    ISSN (online) 2666-6367
    DOI 10.1016/j.jtct.2023.04.013
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  5. Article ; Online: Falciparum malaria associated acute kidney injury with polyneuropathy and intra-arterial thrombosis (stroke)

    Nausheen Butt / Ejaz Ahmed

    European Journal of Medical Research, Vol 27, Iss 1, Pp 1-

    2022  Volume 6

    Abstract: Abstract Background Malaria is still major problem in developing countries, such as Pakistan. Besides fever, body ache and vomiting it can present with acute kidney injury, proteinuria, hematuria and cerebral manifestations which are more common with ... ...

    Abstract Abstract Background Malaria is still major problem in developing countries, such as Pakistan. Besides fever, body ache and vomiting it can present with acute kidney injury, proteinuria, hematuria and cerebral manifestations which are more common with falciparum malaria. Neurological manifestations are rare presentation of malaria and should be consider in patients who are admitting with features of neuropathy and stroke. Case presentation We describe an unusual case of falciparum malaria, complicated by acute kidney injury who developed Polyneuropathy and intra-arterial thrombosis in middle cerebral artery territory. Our patient recovered his renal functions during admission and recovered his power and sensation in his limbs as well after 1 month. Conclusion Malaria cause neurological manifestations including axonal and sensory neuropathy, cerebral venous and arterial thrombosis, PMNS, cerebellar signs and symptoms, psychosis, etc. With prompt diagnosis and early treatment they can be cure and regain their motor and sensory functions to normal level.
    Keywords Malaria ; Acute kidney injury ; Polyneuropathy ; Intra-arterial thrombus ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Falciparum malaria associated acute kidney injury with polyneuropathy and intra-arterial thrombosis (stroke).

    Butt, Nausheen / Ahmed, Ejaz

    European journal of medical research

    2022  Volume 27, Issue 1, Page(s) 2

    Abstract: Background: Malaria is still major problem in developing countries, such as Pakistan. Besides fever, body ache and vomiting it can present with acute kidney injury, proteinuria, hematuria and cerebral manifestations which are more common with falciparum ...

    Abstract Background: Malaria is still major problem in developing countries, such as Pakistan. Besides fever, body ache and vomiting it can present with acute kidney injury, proteinuria, hematuria and cerebral manifestations which are more common with falciparum malaria. Neurological manifestations are rare presentation of malaria and should be consider in patients who are admitting with features of neuropathy and stroke.
    Case presentation: We describe an unusual case of falciparum malaria, complicated by acute kidney injury who developed Polyneuropathy and intra-arterial thrombosis in middle cerebral artery territory. Our patient recovered his renal functions during admission and recovered his power and sensation in his limbs as well after 1 month.
    Conclusion: Malaria cause neurological manifestations including axonal and sensory neuropathy, cerebral venous and arterial thrombosis, PMNS, cerebellar signs and symptoms, psychosis, etc. With prompt diagnosis and early treatment they can be cure and regain their motor and sensory functions to normal level.
    MeSH term(s) Acute Kidney Injury/etiology ; Adolescent ; Humans ; Magnetic Resonance Angiography ; Malaria, Falciparum/complications ; Male ; Middle Cerebral Artery ; Polyneuropathies/etiology ; Thrombotic Stroke/diagnosis ; Thrombotic Stroke/etiology
    Language English
    Publishing date 2022-01-06
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1329381-3
    ISSN 2047-783X ; 0949-2321
    ISSN (online) 2047-783X
    ISSN 0949-2321
    DOI 10.1186/s40001-021-00627-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4636: Show issues Location:
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  7. Article: Benign uptake of

    Hussain, Riffat Parveen / Nausheen, Sadaf / Ahmed, Naveed / Mahmood, Tariq

    World journal of nuclear medicine

    2020  Volume 19, Issue 3, Page(s) 288–290

    Abstract: ... ...

    Abstract 18
    Language English
    Publishing date 2020-07-22
    Publishing country Austria
    Document type Case Reports
    ZDB-ID 2911903-0
    ISSN 1607-3312 ; 1450-1147
    ISSN (online) 1607-3312
    ISSN 1450-1147
    DOI 10.4103/wjnm.WJNM_82_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7137: Show issues Location:
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  8. Article ; Online: Evaluating efficacy and safety of loncastuximab tesirine injection for the treatment of adult patients with relapsed or refractory large B-cell lymphoma.

    Ahmed, Nausheen / Hamadani, Mehdi

    Expert review of anticancer therapy

    2021  Volume 21, Issue 12, Page(s) 1313–1320

    Abstract: Introduction: Relapsed or refractory diffuse large B cell lymphoma (DLBCL) has a poor prognosis. Several novel therapies have gained regulatory approval for treatment of DLBCL, however there is still a need for additional therapies to be added to the ... ...

    Abstract Introduction: Relapsed or refractory diffuse large B cell lymphoma (DLBCL) has a poor prognosis. Several novel therapies have gained regulatory approval for treatment of DLBCL, however there is still a need for additional therapies to be added to the armamentarium. Loncastuximab tesirine-lpyl (ADC Therapeutics), an anti-CD19 antibody-drug conjugate (ADC), was recently approved for the treatment of relapsed, refractory diffuse large B-cell lymphoma (DLBCL).
    Areas covered: We review the design and pharmacologic characteristics of loncastuximab tesirine-lpyl, emphasizing on the significance of CD19 as an effective target as well as pyrrolobenzodiazepine (PBD) as an effective payload. We review the key findings of the phase 1 LOTIS-1 and Phase 2 LOTIS-2 trials of loncastuximab in DLBCL, including efficacy and toxicity profile.
    Expert opinion: Key findings in the early-phase trial support the efficacy of Loncastuximab in DLBCL, including in high-risk subgroups. The side effects have been tolerable even in elderly patients (≥75 years). Several ongoing clinical trials are currently evaluating the safety and efficacy of loncastuximab tesirine in a variety of NHL subtypes, as well as the study of combination strategies.
    MeSH term(s) Aged ; Antibodies, Monoclonal, Humanized/adverse effects ; Antigens, CD19/therapeutic use ; Benzodiazepines ; Humans ; Immunoconjugates/adverse effects ; Lymphoma, Large B-Cell, Diffuse/chemically induced ; Lymphoma, Large B-Cell, Diffuse/drug therapy
    Chemical Substances Antibodies, Monoclonal, Humanized ; Antigens, CD19 ; Immunoconjugates ; Benzodiazepines (12794-10-4) ; loncastuximab tesirine (7K5O7P6QIU)
    Language English
    Publishing date 2021-10-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2112544-2
    ISSN 1744-8328 ; 1473-7140
    ISSN (online) 1744-8328
    ISSN 1473-7140
    DOI 10.1080/14737140.2021.1988853
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5907: Show issues Location:
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  9. Article ; Online: The Cavity as a Lasting Abode for Tuberculous Bacilli: An Observational Study.

    Jawad, Nadia / Jafri, Saira / Saifullah, Nausheen / Ahmed, Naseem

    SN comprehensive clinical medicine

    2022  Volume 4, Issue 1, Page(s) 40

    Abstract: The aim of this study was to determine the factors associated with persistent sputum positivity at the end of 2 months of treatment in patients presenting with (drug-susceptible) pulmonary tuberculosis at a tertiary care hospital in Karachi. A cross- ... ...

    Abstract The aim of this study was to determine the factors associated with persistent sputum positivity at the end of 2 months of treatment in patients presenting with (drug-susceptible) pulmonary tuberculosis at a tertiary care hospital in Karachi. A cross-sectional study was conducted at the Department of Chest Medicine (Ward 12), Jinnah Postgraduate Medical Center (JPMC), Karachi, over 6 months. A sample of 73 consenting, newly diagnosed, smear-positive drug-susceptible pulmonary tuberculosis patients was studied. Demographic (age, gender, height, weight and duration of tuberculosis, BMI, socioeconomic, occupational, marital, educational and residential statuses) and clinical factors (chest X-ray extent and cavities, initial smear results, diabetic and smoking statuses) which may be associated with sputum non-conversion were entered in a proforma. Patients were followed up at 2 months of treatment with a sputum smear. Data analysis was done on SPSS (Statistical Package for Social Sciences-version 20.0). Rate of sputum positivity after 2 months of anti-tubercular drug treatment was 17.8%. None of the above-mentioned demographic and clinical factors was associated with persistence of sputum positivity except for the presence of CXR cavities, which made it 5.5 times more likely that the patient would remain smear-positive at 2 months (
    Supplementary information: The online version contains supplementary material available at 10.1007/s42399-021-01098-6.
    Language English
    Publishing date 2022-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2947211-8
    ISSN 2523-8973 ; 2523-8973
    ISSN (online) 2523-8973
    ISSN 2523-8973
    DOI 10.1007/s42399-021-01098-6
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  10. Article: Incidental Acute Appendicitis on Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) Imaging: Radiology From a Different Perspective.

    Hamid, Samar / Nausheen, Sadaf / Ahmed, Naveed / Hussain, Riffat P / Ihsan, Nida

    Cureus

    2021  Volume 13, Issue 9, Page(s) e17734

    Abstract: Although Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) is routinely used in oncological imaging, the F-18 fluorodeoxyglucose (18F-FDG) avidity is not tumor-specific. Numerous benign infective and ... ...

    Abstract Although Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) is routinely used in oncological imaging, the F-18 fluorodeoxyglucose (18F-FDG) avidity is not tumor-specific. Numerous benign infective and inflammatory processes may also show increased radiotracer activity. Similarly, abnormal 18F-FDG uptake in an inflamed appendix can pose a diagnostic challenge for the interpreter of oncologic 18F-FDG PET/CT. We present the case of an 18-year-old female with classic Hodgkin's lymphoma who had 18F-FDG PET/CT while undergoing chemoradiotherapy. The scan demonstrated a complete metabolic response to treatment. However, there was increased 18F-FDG uptake in the right iliac region, projecting over the appendix, which, if interpreted as a lymphomatous involvement, would have upscaled the treatment response to progressive disease. The patient was called for additional workup, which included an ultrasound abdomen. The scan revealed classic features of acute appendicitis. However, there was no appendicolith or luminal obstruction. Upon additional questioning, the patient mentioned mild intermittent abdominal pain and anorexia eased by pain relievers for the preceding few days. On deep palpation of her abdomen, there was rebound tenderness in the right iliac region. According to the Alvarado score, it was graded 7 points suggesting probable/likely appendicitis. After collective evaluation of the clinical, laboratory, and imaging findings, the appendicular 18F-FDG uptake was deemed secondary to uncomplicated acute appendicitis rather than a lymphomatous lesion. Our patient refused surgery as she did not have severe abdominal pain. She was hemodynamically stable without signs of luminal obstruction. She was non-operatively managed with broad-spectrum antibiotics for six days. The results of the follow-up complete blood counts and ultrasound examination were negative. Our patient was symptom-free and recovering normally at a two-week follow-up appointment. We present a follow-up case of classic Hodgkin's lymphoma with incidental uptake in the appendix, which resembled submucosal lymphomatous cell infiltration of the appendix. Careful scrutiny, clinical correlation, physical examination, blood tests, and additional imaging offered helpful insight and led to the correct, benign diagnosis of the 18F-FDG avid appendix.
    Language English
    Publishing date 2021-09-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.17734
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