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  1. Article ; Online: The HIV epidemic 40 years on.

    Bekker, Linda-Gail

    Nature reviews. Microbiology

    2023  Volume 21, Issue 12, Page(s) 767–768

    MeSH term(s) Humans ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Epidemics
    Language English
    Publishing date 2023-10-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2139054-X
    ISSN 1740-1534 ; 1740-1526
    ISSN (online) 1740-1534
    ISSN 1740-1526
    DOI 10.1038/s41579-023-00979-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A terrific journey for which I have great gratitude.

    Bekker, Linda-Gail

    Southern African journal of infectious diseases

    2022  Volume 37, Issue 2, Page(s) 400

    Language English
    Publishing date 2022-02-14
    Publishing country South Africa
    Document type Journal Article
    ZDB-ID 3046282-4
    ISSN 2313-1810 ; 2312-0053
    ISSN (online) 2313-1810
    ISSN 2312-0053
    DOI 10.4102/sajid.v37i2.400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Strategic planning for the second era of the HIV epidemic.

    Bekker, Linda-Gail / Wood, Robin

    The Lancet. Public health

    2024  Volume 9, Issue 4, Page(s) e208–e209

    MeSH term(s) Humans ; Strategic Planning ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Acquired Immunodeficiency Syndrome ; Epidemics/prevention & control
    Language English
    Publishing date 2024-01-13
    Publishing country England
    Document type Journal Article
    ISSN 2468-2667
    ISSN (online) 2468-2667
    DOI 10.1016/S2468-2667(24)00051-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Long-acting agents for HIV treatment and prevention.

    Bekker, Linda-Gail

    Nature medicine

    2022  Volume 28, Issue 8, Page(s) 1542–1543

    MeSH term(s) Anti-HIV Agents/therapeutic use ; HIV Infections/drug therapy ; HIV Infections/prevention & control ; Humans ; Pre-Exposure Prophylaxis
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2022-07-22
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-022-01917-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: DNA vaccines join the fight against COVID-19.

    Blakney, Anna K / Bekker, Linda-Gail

    Lancet (London, England)

    2022  Volume 399, Issue 10332, Page(s) 1281–1282

    MeSH term(s) COVID-19/prevention & control ; Humans ; Vaccines, DNA/therapeutic use
    Chemical Substances Vaccines, DNA
    Language English
    Publishing date 2022-03-29
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)00524-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: HIV is sexually untransmittable when viral load is undetectable.

    Bekker, Linda-Gail / Smith, Philip / Ntusi, Ntobeko A B

    Lancet (London, England)

    2023  Volume 402, Issue 10400, Page(s) 428–429

    MeSH term(s) Humans ; Viral Load ; Sexual Behavior ; HIV Infections/drug therapy
    Language English
    Publishing date 2023-07-22
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)01519-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: HIV control in young key populations in Africa.

    Bekker, Linda-Gail

    The Lancet. Child & adolescent health

    2019  Volume 3, Issue 7, Page(s) 442–444

    MeSH term(s) Cameroon ; Cross-Sectional Studies ; Female ; HIV Infections ; Homosexuality, Male ; Humans ; Male ; Sex Workers ; Sexual and Gender Minorities
    Language English
    Publishing date 2019-05-16
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2352-4650
    ISSN (online) 2352-4650
    DOI 10.1016/S2352-4642(19)30112-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Interrogating the promise of long-acting HIV pre-exposure prophylaxis.

    Pike, Carey / Bekker, Linda-Gail

    Trends in molecular medicine

    2022  Volume 29, Issue 2, Page(s) 93–98

    Abstract: Oral HIV pre-exposure prophylaxis (PrEP) is a well-established product that provides a safe and highly effective way for individuals to protect themselves against HIV infection. However, hopes of a significant reduction in HIV incidence have been ... ...

    Abstract Oral HIV pre-exposure prophylaxis (PrEP) is a well-established product that provides a safe and highly effective way for individuals to protect themselves against HIV infection. However, hopes of a significant reduction in HIV incidence have been disappointing because of low uptake, adherence challenges to a daily pill regimen, and consistently high discontinuation rates within 6 months of initiation. Long-acting agents have been long awaited for their potential to facilitate adherence and to offer a choice between PrEP products. As the first long-acting agents enter the market, with more poised to follow, questions around how to integrate long-acting agents into oral PrEP platforms, and what the potential advantages and pitfalls of this integration will be, now need to be considered.
    MeSH term(s) Humans ; HIV Infections/prevention & control ; HIV Infections/drug therapy ; Pre-Exposure Prophylaxis ; Anti-HIV Agents/pharmacology ; Anti-HIV Agents/therapeutic use ; Incidence
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2022-11-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2036490-8
    ISSN 1471-499X ; 1471-4914
    ISSN (online) 1471-499X
    ISSN 1471-4914
    DOI 10.1016/j.molmed.2022.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Promises and potential pitfalls of long-acting injectable pre-exposure prophylaxis.

    Pike, Carey / Rousseau, Elzette / Bekker, Linda-Gail

    Southern African journal of HIV medicine

    2023  Volume 24, Issue 1, Page(s) 1497

    Abstract: The number of products that can provide pre-exposure prophylaxis (PrEP) for HIV prevention is expanding, with three now approved in South Africa (oral Tenofovir-based PrEP, injectable Cabotegravir, and a Dapivirine-based vaginal ring) and more in the ... ...

    Abstract The number of products that can provide pre-exposure prophylaxis (PrEP) for HIV prevention is expanding, with three now approved in South Africa (oral Tenofovir-based PrEP, injectable Cabotegravir, and a Dapivirine-based vaginal ring) and more in the development pipeline. Although highly effective and safe, oral PrEP products have not reduced HIV incidence in South Africa to the extent seen in other countries, primarily due to adherence challenges, rapidly diminishing persistence over time, and insufficient scale-up of PrEP service delivery. The Dapivirine vaginal ring, which provides 1-month-long protection, provides women with a new and discreet choice for PrEP; however, it is Cabotegravir long-acting (CAB LA) that is anticipated to land the largest impact. Administered as an intramuscular injection given every 2 months, CAB LA is safe, highly efficacious, and expected to become available in South Africa in late 2023. Yet, clinical and implementation questions remain, including the need to understand and characterise breakthrough HIV infections amongst CAB LA users, knowledge of how to package each PrEP product in a new context of PrEP choice, and how to avoid the remedicalisation of PrEP access following extensive efforts to make oral PrEP delivery differentiated and community based.
    Language English
    Publishing date 2023-07-27
    Publishing country South Africa
    Document type Journal Article ; Review
    ZDB-ID 2259791-8
    ISSN 2078-6751 ; 2078-6751
    ISSN (online) 2078-6751
    ISSN 2078-6751
    DOI 10.4102/sajhivmed.v24i1.1497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Africa and AIDS: still much work to be done.

    Bekker, Linda-Gail / Beyrer, Chris

    The lancet. HIV

    2021  Volume 8, Issue 6, Page(s) e315–e316

    MeSH term(s) Acquired Immunodeficiency Syndrome/epidemiology ; Acquired Immunodeficiency Syndrome/prevention & control ; Africa ; Developing Countries ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Humans
    Language English
    Publishing date 2021-06-04
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ISSN 2352-3018
    ISSN (online) 2352-3018
    DOI 10.1016/S2352-3018(21)00101-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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