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  1. Book: Mathematical models for neglected tropical diseases / Pt. A

    Anderson, Roy M.

    essential tools for control and elimination

    (Advances in parasitology ; 87)

    2015  

    Author's details ed. by Roy M. Anderson
    Series title Advances in parasitology ; 87
    Mathematical models for neglected tropical diseases
    Collection Mathematical models for neglected tropical diseases
    Language English
    Size XVIII, 445 S. : Ill., graph. Darst.
    Edition 1. ed.
    Publisher Elsevier/Academic Press
    Publishing place Amsterdam u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT018598066
    ISBN 978-0-12-803256-5 ; 0-12-803256-1
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Collection: Mathematical models for neglected tropical diseases

    Anderson, Roy M.

    essential tools for control and elimination

    (Advances in parasitology ; ...)

    2015  

    Author's details ed. by Roy M. Anderson
    Series title Advances in parasitology
    ...
    Language English
    Dates of publication 2015-9999
    Publisher Elsevier/Academic Press
    Publishing place Amsterdam u.a.
    Publishing country United States
    Document type Book ; Collection (display volumes)
    HBZ-ID HT018598064
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: An urgent need: vaccines for neglected tropical diseases.

    Anderson, Roy M

    The Lancet. Infectious diseases

    2021  Volume 21, Issue 12, Page(s) 1621–1623

    MeSH term(s) Humans ; Neglected Diseases/prevention & control ; Tropical Medicine ; Vaccines
    Chemical Substances Vaccines
    Language English
    Publishing date 2021-08-19
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(21)00260-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Measuring heterogeneities in soil-transmitted helminth transmission and control.

    Maddren, Rosie / Anderson, Roy M

    Trends in parasitology

    2023  Volume 40, Issue 1, Page(s) 45–59

    Abstract: ... in a population increases. Identifying these remaining pockets of infection requires fine-scale monitoring and evaluation (M ...

    Abstract The global effort over the past decade to control soil-transmitted helminths (STH) has resulted in communities with endemic infection reaching low prevalence levels suitable for the validation of elimination as a public health problem (EPHP), defined by the World Health Organisation (WHO) as <2% of infections classified as moderate or heavy intensity. The spatial scale in which this is validated is currently undefined. As the burden of STH infection decreases, the degree of aggregation of infection within individuals in a population increases. Identifying these remaining pockets of infection requires fine-scale monitoring and evaluation (M&E) programmes that are rarely implemented within current national neglected tropical disease (NTD) control. This review examines various heterogeneities that characterise the epidemiology of STH infections, and discusses their impact on control policy formulation.
    MeSH term(s) Animals ; Humans ; Soil/parasitology ; Helminths ; Helminthiasis/epidemiology ; Helminthiasis/prevention & control ; Helminthiasis/parasitology ; Prevalence
    Chemical Substances Soil
    Language English
    Publishing date 2023-12-11
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2036227-4
    ISSN 1471-5007 ; 1471-4922
    ISSN (online) 1471-5007
    ISSN 1471-4922
    DOI 10.1016/j.pt.2023.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Keys to the nematode parasites of vertebrates / Archival vol. / ed. by Roy C. Anderson ...

    Gibbons, Lynda M. / Anderson, Roy C.

    2009  

    Institution Commonwealth Institute of Helminthology
    Collection Keys to the nematode parasites of vertebrates
    Language English
    Size X, 463 S. : Ill.
    Publisher Cabi
    Publishing place Wallingford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015902059
    ISBN 978-1-84593-572-6 ; 1-84593-572-1
    Database Catalogue ZB MED Medicine, Health

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  6. Book: Keys to the nematode parasites of vertebrates / Suppl. vol.

    Gibbons, Lynda M. / Anderson, Roy C.

    2010  

    Institution Commonwealth Institute of Helminthology
    Collection Keys to the nematode parasites of vertebrates
    Language English
    Size VIII, 416 S. : Ill.
    Publisher Cabi
    Publishing place Wallingford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015902062
    ISBN 978-1-84593-571-9 ; 1-84593-571-3
    Database Catalogue ZB MED Medicine, Health

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  7. Book ; Collection: Keys to the nematode parasites of vertebrates

    Gibbons, Lynda M. / Anderson, Roy C.

    2009  

    Institution Commonwealth Institute of Helminthology
    Language English
    Dates of publication 2009-9999
    Publisher Cabi
    Publishing place Wallingford u.a.
    Publishing country Great Britain
    Document type Book ; Collection (display volumes)
    Old title Frühere Ausg. u.d.T. Commonwealth Institute of Helminthology <Saint Albans>: CIH keys to the nematode parasites of vertebrates
    HBZ-ID HT015902039
    Database Catalogue ZB MED Medicine, Health

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  8. Article ; Online: Validation of antibodies: Lessons learned from the Common Fund Protein Capture Reagents Program.

    Roy, Ananda L / Wilder, Elizabeth L / Anderson, James M

    Science advances

    2021  Volume 7, Issue 46, Page(s) eabl7148

    Abstract: Large-scale generation of protein capture reagents remains a technical challenge, but their generation is just the beginning. Validation is a critical, iterative process that yields different results for different uses. Independent, community-based ... ...

    Abstract Large-scale generation of protein capture reagents remains a technical challenge, but their generation is just the beginning. Validation is a critical, iterative process that yields different results for different uses. Independent, community-based validation offers the possibility of transparent data sharing, with use case–specific results made broadly available. This type of resource, which can grow as new validation data are obtained for an expanding group of reagents, provides a community resource that should accompany future reagent-generating efforts. To address a pressing need for antibodies or other reagents that recognize human proteins, the National Institutes of Health Common Fund launched the Protein Capture Reagents Program in 2010 as a pilot to target human transcription factors. Here, we describe lessons learned from this program concerning generation and validation of research reagents, which we believe are generally applicable for future research endeavors working in a similar space.
    Language English
    Publishing date 2021-11-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.abl7148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Probability distributions of helminth parasite burdens within the human host population following repeated rounds of mass drug administration and their impact on the transmission breakpoint.

    Collyer, Benjamin S / Anderson, Roy M

    Journal of the Royal Society, Interface

    2021  Volume 18, Issue 177, Page(s) 20210200

    Abstract: The existence of multiple stable equilibria in models of parasitic helminth transmission was a ground-breaking discovery over 30 years ago. An implication of this discovery, that there is a level of infection below which transmission cannot self-sustain ... ...

    Abstract The existence of multiple stable equilibria in models of parasitic helminth transmission was a ground-breaking discovery over 30 years ago. An implication of this discovery, that there is a level of infection below which transmission cannot self-sustain called the transmission breakpoint, has in part motivated the push towards the elimination of many human diseases caused by the multiple species of helminth worldwide. In the absence of vaccines, the predominant method in this push towards elimination is to repeatedly administer endemic populations with anthelmintic drugs, over several treatment rounds, in what has become to be known as mass drug administration (MDA). MDA will inevitably alter the distribution of parasite burdens among hosts from the baseline distribution, and significantly, the location of the transmission breakpoint is known to be dependent on the level of aggregation of this distribution-for a given mean worm burden, more highly aggregated distributions where fewer individuals harbour most of the burden, will have a lower transmission breakpoint. In this paper, we employ a probabilistic analysis of the changes to the distribution of burdens in a population undergoing MDA, and simple approximations, to determine how key aspects of the programmes (including compliance, drug efficacy and treatment coverage) affect the location of the transmission breakpoint. We find that individual compliance to treatment, which determines the number of times an individual participates in mass drug administration programmes, is key to the location of the breakpoint, indicating the vital importance to ensure that people are not routinely missed in these programmes.
    MeSH term(s) Animals ; Helminthiasis/drug therapy ; Helminthiasis/epidemiology ; Helminths ; Humans ; Mass Drug Administration ; Parasites ; Probability
    Language English
    Publishing date 2021-04-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2156283-0
    ISSN 1742-5662 ; 1742-5689
    ISSN (online) 1742-5662
    ISSN 1742-5689
    DOI 10.1098/rsif.2021.0200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Introduction to the special issue: challenges and opportunities in the fight against neglected tropical diseases: a decade from the London Declaration on NTDs.

    Forbes, Kathryn / Basáñez, Maria-Gloria / Hollingsworth, T Déirdre / Anderson, Roy M

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences

    2023  Volume 378, Issue 1887, Page(s) 20220272

    Abstract: Twenty neglected tropical diseases (NTDs) are currently prioritised by the World Health Organization for eradication, elimination as a public health problem, elimination of transmission or control by 2030. This issue celebrates progress made since the ... ...

    Abstract Twenty neglected tropical diseases (NTDs) are currently prioritised by the World Health Organization for eradication, elimination as a public health problem, elimination of transmission or control by 2030. This issue celebrates progress made since the 2012 London Declaration on NTDs and discusses challenges currently faced to achieve these goals. It comprises 14 contributions spanning NTDs tackled by intensified disease management to those addressed by preventive chemotherapy. Although COVID-19 negatively affected NTD programmes, it also served to spur new multisectoral approaches to strengthen school-based health systems. The issue highlights the needs to improve impact survey design, evaluate new diagnostics, understand the consequences of heterogeneous prevalence and human movement, the potential impact of alternative treatment strategies and the importance of zoonotic transmission. This article is part of the theme issue 'Challenges and opportunities in the fight against neglected tropical diseases: a decade from the London Declaration on NTDs'.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; London/epidemiology ; Movement ; Neglected Diseases/epidemiology ; Neglected Diseases/prevention & control
    Language English
    Publishing date 2023-08-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208382-6
    ISSN 1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
    ISSN (online) 1471-2970
    ISSN 0080-4622 ; 0264-3839 ; 0962-8436
    DOI 10.1098/rstb.2022.0272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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