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  1. Article ; Online: High-Precision Photoacoustic Nitrogen Dioxide Gas Analyzer for Fast Dynamic Measurement.

    Qi, Hongchao / Zhang, Guangyin / Xu, Lin / Yang, Ling / Wang, Zhengzhi / Xu, Yufu / Chen, Ke

    Analytical chemistry

    2024  Volume 96, Issue 3, Page(s) 1354–1361

    Abstract: A high-precision photoacoustic (PA) gas analyzer for fast dynamic measurement of ambient nitrogen dioxide ( ... ...

    Abstract A high-precision photoacoustic (PA) gas analyzer for fast dynamic measurement of ambient nitrogen dioxide (NO
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c05084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Rapid Photoacoustic Exhaust Gas Analyzer for Simultaneous Measurement of Nitrogen Dioxide and Sulfur Dioxide.

    Qi, Hongchao / Zhao, Xinyu / Xu, Yufu / Yang, Ling / Liu, Junjun / Chen, Ke

    Analytical chemistry

    2024  Volume 96, Issue 13, Page(s) 5258–5264

    Abstract: A rapid photoacoustic (PA) exhaust gas analyzer is presented for simultaneous measurements of nitrogen dioxide ( ... ...

    Abstract A rapid photoacoustic (PA) exhaust gas analyzer is presented for simultaneous measurements of nitrogen dioxide (NO
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c05936
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: High-Precision Multipass Fiber-Optic Photoacoustic Gas Analyzer Based on 2

    Xu, Yufu / Wang, Heng / Qi, Hongchao / Zhao, Xinyu / Guo, Min / Zhang, Yajie / Li, Chenxi / Chen, Ke

    Analytical chemistry

    2024  Volume 96, Issue 6, Page(s) 2543–2549

    Abstract: A self-calibration fiber-optic photoacoustic (PA) gas analyzer based on ... ...

    Abstract A self-calibration fiber-optic photoacoustic (PA) gas analyzer based on 2
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c04951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Correction to: Toll-like receptor 4 deficiency ameliorates β2-microglobulin induced age-related cognition decline due to neuroinflammation in mice.

    Zhong, Qi / Zou, Yufeng / Liu, Hongchao / Chen, Ting / Zheng, Feng / Huang, Yifei / Chen, Chang / Zhang, Zongze

    Molecular brain

    2024  Volume 17, Issue 1, Page(s) 19

    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2436057-0
    ISSN 1756-6606 ; 1756-6606
    ISSN (online) 1756-6606
    ISSN 1756-6606
    DOI 10.1186/s13041-024-01090-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sample size calculation for clinical trials analyzed with the meta-analytic-predictive approach.

    Qi, Hongchao / Rizopoulos, Dimitris / van Rosmalen, Joost

    Research synthesis methods

    2023  Volume 14, Issue 3, Page(s) 396–413

    Abstract: The meta-analytic-predictive (MAP) approach is a Bayesian method to incorporate historical controls in new trials that aims to increase the statistical power and reduce the required sample size. Here we investigate how to calculate the sample size of the ...

    Abstract The meta-analytic-predictive (MAP) approach is a Bayesian method to incorporate historical controls in new trials that aims to increase the statistical power and reduce the required sample size. Here we investigate how to calculate the sample size of the new trial when historical data is available, and the MAP approach is used in the analysis. In previous applications of the MAP approach, the prior effective sample size (ESS) acted as a metric to quantify the number of subjects the historical information is worth. However, the validity of using the prior ESS in sample size calculation (i.e., reducing the number of randomized controls by the derived prior ESS) is questionable, because different approaches may yield different values for prior ESS. In this work, we propose a straightforward Monte Carlo approach to calculate the sample size that achieves the desired power in the new trial given available historical controls. To make full use of the available historical information to simulate the new trial data, the control parameters are not taken as a point estimate but sampled from the MAP prior. These sampled control parameters and the MAP prior based on the historical data are then used to derive the statistical power for the treatment effect and the resulting required sample size. The proposed sample size calculation approach is illustrated with real-life data sets with different outcomes from three studies. The results show that this approach to calculating the required sample size for the MAP analysis is straightforward and generic.
    MeSH term(s) Humans ; Sample Size ; Models, Statistical ; Bayes Theorem ; Monte Carlo Method ; Research Design ; Computer Simulation
    Language English
    Publishing date 2023-01-14
    Publishing country England
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 2548499-0
    ISSN 1759-2887 ; 1759-2879
    ISSN (online) 1759-2887
    ISSN 1759-2879
    DOI 10.1002/jrsm.1618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Fiber-Optic Photoacoustic CO Sensor for Gas Insulation Equipment Monitoring Based on Cantilever Differential Lock-In Amplification and Optical Excitation Enhancement.

    Zhao, Xinyu / Ma, Fengxiang / Wang, Heng / Qi, Hongchao / Li, Chenxi / Guo, Min / Chen, Ke

    Analytical chemistry

    2024  Volume 96, Issue 13, Page(s) 5298–5306

    Abstract: A fiber-optic photoacoustic CO sensor for gas insulation equipment is proposed, which relies on F-P interferometric cantilever-based differential lock-in amplification and optical multipass excitation enhancement. The sensor has excellent characteristics ...

    Abstract A fiber-optic photoacoustic CO sensor for gas insulation equipment is proposed, which relies on F-P interferometric cantilever-based differential lock-in amplification and optical multipass excitation enhancement. The sensor has excellent characteristics of high sensitivity, antielectromagnetic interference, fast response, and long-distance detection. The photoacoustic pressure waves in the two resonators of the differential photoacoustic cell (DPAC) are simultaneously detected by two fiber-optic interferometric cantilevers and processed differentially; thereby, the gas flow noise is effectively suppressed. Based on the comprehensive analysis of the superposition of photoacoustic excitation and multipass absorption, the diameter of the resonator is determined to be 6 mm. The optical power emitted by the 1566.6 nm distributed feedback laser is increased to 500 mW by an erbium-doped fiber amplifier. The near-infrared light is reflected 30 times in the multipass cell, which improves the order of magnitude of optical effective excitation. Due to the low sound velocity of SF
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.4c00233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Differential Cantilever Enhanced Fiber-Optic Photoacoustic Sensor for Diffusion Gas Detection.

    Li, Chenxi / Zhang, Yajie / Guo, Min / Qi, Hongchao / Zhao, Xinyu / Chen, Ke

    Analytical chemistry

    2024  Volume 96, Issue 11, Page(s) 4562–4569

    Abstract: Aiming at the problem of the fiber-optic photoacoustic (PA) sensor being easily disturbed by external vibration and noise, a differential cantilever enhanced fiber-optic PA sensor is proposed for diffusion gas detection. The sensor comprises two PA tubes ...

    Abstract Aiming at the problem of the fiber-optic photoacoustic (PA) sensor being easily disturbed by external vibration and noise, a differential cantilever enhanced fiber-optic PA sensor is proposed for diffusion gas detection. The sensor comprises two PA tubes with the same structure and a pair of differential interferometric cantilevers. The two PA tubes are symmetrically distributed. The laser is incident on the PA tube as the signal channel to excite the PA pressure wave. Another tube without incident laser is used as the reference channel to suppress external disturbance. The external interference signals and PA signals superimposed with disturbance are detected by the differential cantilevers from the two channels. The signals are simultaneously restored by a single white-light interferometry demodulator, which multiplexed the spectral frequency domain of the superimposed interference spectrum. The experimental results show that the suppression effect of the differential cantilever enhanced PA sensor on ambient noise is improved by 80%, compared to the traditional single-cantilever sensor. The external cofrequency disturbance is suppressed by 20.9 dB. The minimum detection limit to acetylene (C
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c05396
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Dense Multibutterfly Spots-Enhanced Miniaturized Optical Fiber Photoacoustic Gas Sensor.

    Zhao, Xinyu / Qi, Hongchao / Wang, Heng / Wang, Xiaona / Guo, Min / Peng, Wei / Chen, Ke

    Analytical chemistry

    2024  Volume 96, Issue 14, Page(s) 5554–5559

    Abstract: A miniaturized optical fiber photoacoustic gas sensor enhanced by dense multibutterfly spots is reported for the first time. The principle of space light transmission of neglecting paraxial approximation is theoretically analyzed for designing a dense ... ...

    Abstract A miniaturized optical fiber photoacoustic gas sensor enhanced by dense multibutterfly spots is reported for the first time. The principle of space light transmission of neglecting paraxial approximation is theoretically analyzed for designing a dense multibutterfly spots-based miniature multipass cell. In a multipass photoacoustic tube with a diameter of 16 mm, the light beam is reflected about a hundred times. The light spots on the mirror surfaces at both ends of the photoacoustic tube form a dense multibutterfly distribution. The volume of the micro multipass gas chamber is only 5.3 mL. An optical fiber cantilever based on F-P interference is utilized as a photoacoustic pressure detector. Compared with that of the single-pass structure, the gas detection ability of the photoacoustic system with dense multibutterfly spots is improved by about 50 times. The proposed miniaturized sensor realizes a detection limit of 3.4 ppb for C
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.4c00005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dynamic detection of ppb-level SO

    Zhao, Xinyu / Qi, Hongchao / Xu, Yufu / Li, Chenxi / Guo, Min / Zhao, Jikuan / Cui, Dongyu / Chen, Ke

    Optics letters

    2023  Volume 48, Issue 17, Page(s) 4558–4561

    Abstract: We design a photoacoustic (PA) ... ...

    Abstract We design a photoacoustic (PA) SO
    Language English
    Publishing date 2023-07-15
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.498908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Female Reproductive Factors and Risk of New-Onset Heart Failure: Findings From UK Biobank.

    Zhu, Fang / Qi, Hongchao / Bos, Maxime / Boersma, Eric / Kavousi, Maryam

    JACC. Heart failure

    2023  Volume 11, Issue 9, Page(s) 1203–1212

    Abstract: Background: A comprehensive evaluation of woman-specific risk factors in relation to incident heart failure (HF) is limited.: Objectives: This study sought to investigate the association of multiple female reproductive factors with the risk of HF.: ...

    Abstract Background: A comprehensive evaluation of woman-specific risk factors in relation to incident heart failure (HF) is limited.
    Objectives: This study sought to investigate the association of multiple female reproductive factors with the risk of HF.
    Methods: Between 2007 and 2010, 229,026 women (mean age: 56.5 years) without prevalent HF from the UK Biobank cohort were included and followed until December 2020. The relation between (self-reported) reproductive factors and HF was analyzed using Cox proportional hazards models with adjustment for potential confounding.
    Results: Menarche at age <12 years, compared to age 12-13 years, carried a 9% larger risk of HF (HR: 1.09 [95% CI: 1.01-1.18]). Younger age at menopause was associated with a higher risk of HF (HR
    Conclusions: The findings emphasize the importance of female reproductive history in the assessment of HF risk.
    MeSH term(s) Child ; Humans ; Female ; Middle Aged ; Adolescent ; Young Adult ; Adult ; Heart Failure/epidemiology ; Prospective Studies ; Reproductive History ; Biological Specimen Banks ; Risk Factors ; United Kingdom/epidemiology
    Language English
    Publishing date 2023-04-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2023.02.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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