LIVIVO - Search results -

Search results

Result 1 - 10 of total 1251

Search options

Article ; Online: Identification of the atypically modified autoantigen Ars2 as the target of B-cell receptors from activated B-cell-type diffuse large B-cell lymphoma.

Thurner, Lorenz / Hartmann, Sylvia / Bewarder, Moritz / Fadle, Natalie / Regitz, Evi / Schormann, Claudia / Quiroga, Natalia / Kemele, Maria / Klapper, Wolfram / Rosenwald, Andreas / Trümper, Lorenz / Bohle, Rainer Maria / Nimmesgern, Anna / Körbel, Christina / Lascke, Matthias W / Menger, Michael D / Barth, Stefan / Kubuschok, Boris / Mottok, Anja /

Kaddu-Mulindwa, Dominic / Hansmann, Martin-Leo / Pöschel, Viola / Held, Gerhard / Murawski, Niels / Stilgenbauer, Stephan / Neumann, Frank / Preuss, Klaus-Dieter / Pfreundschuh, Michael

Haematologica

2021 Volume 106, Issue 8, Page(s) 2224–2232

Abstract: It has been suggested that B-cell receptor (BCRs) stimulation by specific antigens plays ... a pathogenic role in diffuse large B-cell lymphoma (DLBCL). Here, it was the aim to screen for specific ... type, but only 1/20 germinal center B cell (GBC)-like type DLBCL. Incubation with Ars2 induced BCR ...

Abstract	It has been suggested that B-cell receptor (BCRs) stimulation by specific antigens plays a pathogenic role in diffuse large B-cell lymphoma (DLBCL). Here, it was the aim to screen for specific reactivities of DLBCL-BCRs in the spectrum of autoantigens and antigens of infectious origin. Arsenite resistance protein 2 (Ars2) was identified as the BCR target of 3/5 ABC-type DLBCL cell lines and 2/11 primary DLBCL cases. Compared to controls, Ars2 was hypo-phosphorylated exclusively in cases and cell lines with Ars2-specific BCRs. In a validation cohort, hypo-phosphorylated Ars2 was found in 8/31 ABC-type, but only 1/20 germinal center B cell (GBC)-like type DLBCL. Incubation with Ars2 induced BCR-pathway activation and increased proliferation, while an Ars2/ETA-toxin conjugate induced killing of cell lines with Ars2-reactive BCRs. Ars2 appears to play a role in a subgroup of ABC-type DLBCLs. Moreover, transformed DLBCL lines with Ars2-reactive BCRs still show growth advantage after incubation with Ars2. These results provide knowledge about the pathogenic role of a specific antigen stimulating the BCR pathway in DLCBL.
MeSH term(s)	Autoantigens ; B-Lymphocytes ; Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Receptors, Antigen, B-Cell/genetics ; Signal Transduction
Chemical Substances	Autoantigens ; Receptors, Antigen, B-Cell
Language	English
Publishing date	2021-08-01
Publishing country	Italy
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2333-4
ISSN	1592-8721 ; 0017-6567 ; 0390-6078
ISSN (online)	1592-8721
ISSN	0017-6567 ; 0390-6078
DOI	10.3324/haematol.2019.241653
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh III Zs.76: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: The yield and impact of pulmonologist-performed EUS-B-FNA of subdiaphragmatic lesions-an institutional experience.

Jeffus, Susanne / Quiroga, Eleonora Fiorletta / Hasan, Zeinab / Fedda, Faysal / Meena, Nikhil / Bartter, Thaddeus

Journal of the American Society of Cytopathology

2023 Volume 12, Issue 5, Page(s) 362–367

Abstract: ... curvilinear ultrasound bronchoscope via the esophagus (EUS-B). The literature with respect to the value of EUS ... B, rapid on-site evaluation, and final diagnostic yield for structures below the diaphragm is ... retrospectively for EUS-B fine needle aspirations (FNAs) from 2013 to 2021. All procedures involving EUS-B-FNA ...

Abstract	Introduction: Pulmonologists can biopsy structures below the diaphragm using the convex curvilinear ultrasound bronchoscope via the esophagus (EUS-B). The literature with respect to the value of EUS-B, rapid on-site evaluation, and final diagnostic yield for structures below the diaphragm is limited. We review our institutional experience. Materials and methods: Our database was queried retrospectively for EUS-B fine needle aspirations (FNAs) from 2013 to 2021. All procedures involving EUS-B-FNA of subdiaphragmatic structures were selected for analysis. The following data elements were collected for each patient: age, gender, clinical indication, sample site, on-site adequacy (OSA), preliminary and final diagnoses, and sufficiency of cell block for ancillary studies. Results: A total of 75 subdiaphragmatic sites were biopsied in 74 patients. Of which, 87% of samples subjected to rapid on-site evaluation were deemed to contain adequate material (OSA+). There were no false-positive OSAs. Six cases remained nondiagnostic at the final diagnosis. The final diagnostic yield (with cell block) was 92% (69/75 cases). Cell block was sufficient for immunohistochemistry or special stains in all applicable cases (n = 36). Molecular testing was requested for 11 cases and successful in 10 (91%). Sampling of subdiaphragmatic sites changed the stage in 67% (38/57) of lung cancer patients. Conclusions: Pulmonologists can perform EUS-B-FNA of subdiaphragmatic sites with high OSA and final diagnostic yield when assisted by cytopathologists. Strong correlations exist between OSA, cell block adequacy, and subsequent capacity to perform ancillary testing. EUS-B below the diaphragm can make an important contribution to the diagnosis of lung cancer, nonpulmonary malignancies, and other diseases.
MeSH term(s)	Humans ; Retrospective Studies ; Pulmonologists ; Endosonography/methods ; Endoscopic Ultrasound-Guided Fine Needle Aspiration/methods ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/pathology
Language	English
Publishing date	2023-05-26
Publishing country	United States
Document type	Review ; Journal Article
ISSN	2213-2945
ISSN	2213-2945
DOI	10.1016/j.jasc.2023.05.004
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Book ; Online ; Thesis: Antigene zur B-Zellrezeptor-gerichteten Therapie des diffus großzelligen B-Zell-Lymphoms

Quiroga Arauco, Natalia [Verfasser]

2020

Author's details	Natalia Quiroga Arauco
Keywords	Medizin, Gesundheit ; Medicine, Health
Subject code	sg610
Language	German
Publisher	Saarländische Universitäts- und Landesbibliothek
Publishing place	Saarbrücken
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Beneficial effect of temporary methotrexate interruption on B and T cell responses upon SARS-CoV-2 vaccination in patients with rheumatoid arthritis or psoriatic arthritis.

Martínez-Fleta, Pedro / Vicente-Rabaneda, Esther F / Triguero-Martínez, Ana / Roy-Vallejo, Emilia / Uriarte-Ecenarro, Miren / Gutiérrez-Rodríguez, Francisco / Quiroga-Colina, Patricia / Romero-Robles, Ana / Montes, Nuria / García-Castañeda, Noelia / Mejía-Abril, Gina P / García-Vadillo, Jesús A / Llorente-Cubas, Irene / Villagrasa, José R / Serra López-Matencio, José M / Ancochea, Julio / Urzainqui, Ana / Esparcia-Pinedo, Laura / Alfranca, Arantzazu /

de la Fuente, Hortensia / García-Vicuña, Rosario / Sánchez-Madrid, Francisco / González-Álvaro, Isidoro / Castañeda, Santos

NPJ vaccines

2024 Volume 9, Issue 1, Page(s) 21

Abstract: B and T cell responses were evaluated in patients with rheumatoid arthritis (RA) or ...

Abstract	B and T cell responses were evaluated in patients with rheumatoid arthritis (RA) or psoriatic arthritis (PsA) after 1 or 2 weeks of methotrexate (MTX) withdrawal following each COVID-19 vaccine dose and compared with those who maintained MTX. Adult RA and PsA patients treated with MTX were recruited and randomly assigned to 3 groups: MTX-maintenance (n = 72), MTX-withdrawal for 1 week (n = 71) or MTX-withdrawal for 2 weeks (n = 73). Specific antibodies to several SARS-CoV-2 antigens and interferon (IFN)-γ and interleukin (IL)-21 responses were assessed. MTX withdrawal in patients without previous COVID-19 was associated with higher levels of anti-RBD IgG and neutralising antibodies, especially in the 2-week withdrawal group and with higher IFN-γ secretion upon stimulation with pools of SARS-CoV-2 S peptides. No increment of RA/PsA relapses was detected across groups. Our data indicate that two-week MTX interruption following COVID-19 vaccination in patients with RA or PsA improves humoral and cellular immune responses.
Language	English
Publishing date	2024-01-30
Publishing country	England
Document type	Journal Article
ISSN	2059-0105
ISSN (online)	2059-0105
DOI	10.1038/s41541-024-00805-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Hepatitis b y c en personas con vih del instituto para el desarrollo humano

Jhemel Garay Quiroga / Edgar Valdez Carrizo

Ciencia Médica, Vol 24, Iss

2022 Volume 1

Abstract: Introducción: La coinfección del VIH con la hepatitis B o C es causa de patología hepática crónica ... de hepatitis B y C en personas con VIH que acuden a consulta en el Instituto para el Desarrollo Humano ... de superficie del virus hepatitis B, anticuer- po anti-core del virus de hepatitis B, anticuerpo contra el virus ...

Abstract	Introducción: La coinfección del VIH con la hepatitis B o C es causa de patología hepática crónica, con diversas seroprevalencias en diferentes regiones del mundo. Objetivo: Conocer la seroprevalencia de hepatitis B y C en personas con VIH que acuden a consulta en el Instituto para el Desarrollo Humano, Cochabamba-Bolivia, gestión 2017-2018. Materiales y Métodos: Estudio descriptivo, prospectivo-transversal, cuantitativo, no experimental.Se analizaron los resultados serológicos de los marcadores: Antígeno de superficie del virus hepatitis B, anticuer- po anti-core del virus de hepatitis B, anticuerpo contra el virus hepatitis C; historial de vacuna para hepatitis B y esquema de tratamiento antirretroviral, de 195 personas con VIH en el Instituto para el Desarrollo Humano, se realizó análisis bivariado para la obtención de datos. Resultados: La seroprevalencia obtenida para hepatitis B es de 7,7% y hepatitis C de 0,5%; la coinfección entre VIH y hepatitis B es de 80% con esquema antirretroviral tenofovir/lamivudina. El grupo poblacional homosexual tiene un riesgo de 5,5 veces más de tener la co-infección de VIH y hepatitis B con un valor de p de 0,006; con relación a la inmunización para hepatitis B solo el 9,2% de los pacientes cuentan con el esquema completo. Conclusión: Es imperativo ofertar las pruebas para hepatitis B y C a todas las personas con VIH; haciendo énfasis en los grupos más vulnerables (homosexuales); es importante el abastecimiento de dosis para la inmunización completa contra la hepatitis B en todos los servicios de salud públicos del país.
Keywords	Medicine (General) ; R5-920
Language	Spanish
Publishing date	2022-04-01T00:00:00Z
Publisher	Universidad Mayor de San Simón, Facultad de Medicina
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: B Cells Adapt Their Nuclear Morphology to Organize the Immune Synapse and Facilitate Antigen Extraction.

Ulloa, Romina / Corrales, Oreste / Cabrera-Reyes, Fernanda / Jara-Wilde, Jorge / Saez, Juan José / Rivas, Christopher / Lagos, Jonathan / Härtel, Steffen / Quiroga, Clara / Yuseff, María-Isabel / Diaz-Muñoz, Jheimmy

Frontiers in immunology

2022 Volume 12, Page(s) 801164

Abstract: Upon interaction with immobilized antigens, B cells form an immune synapse where actin remodeling ... antigen extraction. B cells have restricted cytoplasmic space, mainly occupied by a large nucleus ... that upon activation, B cells re-orientate and adapt the size of their nuclear groove facing the immune synapse ...

Abstract	Upon interaction with immobilized antigens, B cells form an immune synapse where actin remodeling and re-positioning of the microtubule-organizing center (MTOC) together with lysosomes can facilitate antigen extraction. B cells have restricted cytoplasmic space, mainly occupied by a large nucleus, yet the role of nuclear morphology in the formation of the immune synapse has not been addressed. Here we show that upon activation, B cells re-orientate and adapt the size of their nuclear groove facing the immune synapse, where the MTOC sits, and lysosomes accumulate. Silencing the nuclear envelope proteins Nesprin-1 and Sun-1 impairs nuclear reorientation towards the synapse and leads to defects in actin organization. Consequently, B cells are unable to internalize the BCR after antigen activation. Nesprin-1 and Sun-1-silenced B cells also fail to accumulate the tethering factor Exo70 at the center of the synaptic membrane and display defective lysosome positioning, impairing efficient antigen extraction at the immune synapse. Thus, changes in nuclear morphology and positioning emerge as critical regulatory steps to coordinate B cell activation.
MeSH term(s)	Actins/metabolism ; Antigens/metabolism ; B-Lymphocytes ; Receptors, Antigen, B-Cell/metabolism ; Synapses/metabolism
Chemical Substances	Actins ; Antigens ; Receptors, Antigen, B-Cell
Language	English
Publishing date	2022-02-09
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2021.801164
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Characterization of syndromic, nonsyndromic familial, and sporadic type B aortic dissection.

Shalhub, Sherene / Rah, Jasmine Y / Campbell, Rebecca / Sweet, Matthew P / Quiroga, Elina / Starnes, Benjamin W

Journal of vascular surgery

2020 Volume 73, Issue 6, Page(s) 1906–1914.e2

Abstract: Objective: Type B aortic dissection (TBAD) is commonly thought of as a sporadic event ...

Abstract	Objective: Type B aortic dissection (TBAD) is commonly thought of as a sporadic event. However, an increasing body of data has suggested that genetic factors can influence TBAD. Our aim was to determine the prevalence of heritable TBAD, defined as either syndromic TBAD or nonsyndromic familial TBAD and to detail the natural history and long-term clinical outcomes compared with patients with "sporadic" TBAD without an identified syndrome or family history. Methods: The clinical records of 389 patients with TBAD who had presented to a single health care system from 1995 to 2017 were reviewed. A family history was obtained by interview and/or medical record review. Syndromic TBAD was defined as TBAD in patients with Marfan, Loeys-Dietz, or vascular Ehlers-Danlos syndrome. Nonsyndromic familial TBAD was defined as a family history of aortic or arterial aneurysm or dissection and/or sudden death in a first- or second-degree relative in the absence of a known syndrome. Patients with syndromic and nonsyndromic familial TBAD were compared with patients with sporadic TBAD in terms of the comorbid conditions, aortic repair, and mortality. Results: Of 389 patients (71.2% male) with TBAD, the etiology of TBAD was heritable in 27.9% (9.6% syndromic; 18.3% nonsyndromic familial TBAD) and 72.1% sporadic of the cases. Patients with syndromic and nonsyndromic familial TBAD had been more frequently referred in the chronic phase than were the patients with sporadic TBAD (35.5% vs 44.1% vs 25.8%; P = .014) and had presented at a younger age (40.6 ± 10.9 years vs 55.2 ± 11.3 years vs 62 ± 12.9 years; P < .001) and with lower blood pressure at acute TBAD (systolic, 159.2 ± 21 mm Hg vs 178.9 ± 39.3 mm Hg vs 186.1 ± 38.4, P = .01; diastolic, 84.3 ± 17.3 mm Hg vs 91.4 ± 24.1 mm Hg vs 101.6 ± 22.3 mm Hg, P = .001). Among patients with acute TBAD surviving to discharge from the initial hospitalization, thoracic endovascular aortic repair (TEVAR) had been performed in 115 patients, with no significant differences in TEVAR usage in the three groups. However, those with syndromic and nonsyndromic familial TBAD had had a greater incidence of retrograde aortic dissection after TEVAR (33.3% vs 15% vs 3%; P = .006). They had also required a greater number of arch repairs (30% vs 10.5% vs 3.6%; P < .001) and had died at a younger age (47.7 ± 13.1 years vs 65.7 ± 13.7 years vs 72.8 ± 12.7 years; P < .001). Aortic-related mortality was more common among patients with syndromic TBAD (36.7% vs 12.3% vs 17.6%; P = .016). Conclusions: In our single-institutional experience, heritable TBAD accounted for one in four patients with TBAD. Nonsyndromic familial TBAD was twice as common as syndromic TBAD and appeared to share many clinical features. Identifying these patients early in their disease course and personalizing their care might improve their survival.
MeSH term(s)	Adult ; Aged ; Aneurysm, Dissecting/epidemiology ; Aneurysm, Dissecting/genetics ; Aneurysm, Dissecting/mortality ; Aneurysm, Dissecting/surgery ; Aortic Aneurysm, Thoracic/epidemiology ; Aortic Aneurysm, Thoracic/genetics ; Aortic Aneurysm, Thoracic/mortality ; Aortic Aneurysm, Thoracic/surgery ; Blood Vessel Prosthesis Implantation ; Endovascular Procedures ; Female ; Genetic Predisposition to Disease ; Heredity ; Humans ; Male ; Middle Aged ; Pedigree ; Phenotype ; Prevalence ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
Language	English
Publishing date	2020-11-27
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	605700-7
ISSN	1097-6809 ; 0741-5214
ISSN (online)	1097-6809
ISSN	0741-5214
DOI	10.1016/j.jvs.2020.10.080
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1933: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Hepatitis B y C en personas con VIH del instituto para el desarrollo humano

Jhemel Garay Quiroga / Edgar Valdez Carrizo

Ciencia Médica, Vol 24, Iss

2021 Volume 1

Abstract	Introducción: La coinfección del VIH con la hepatitis B o C es causa de patología hepática crónica, con diversas seroprevalencias en diferentes regiones del mundo. Objetivo: Conocer la seroprevalencia de hepatitis B y C en personas con VIH que acuden a consulta en el Instituto para el Desarrollo Humano, Cochabamba-Bolivia, gestión 2017-2018. Materiales y Métodos: Estudio descriptivo, prospectivo-transversal, cuantitativo, no experimental. Se analizaron los resultados serológicos de los marcadores: Antígeno de superficie del virus hepatitis B, anticuer- po anti-core del virus de hepatitis B, anticuerpo contra el virus hepatitis C; historial de vacuna para hepatitis B y esquema de tratamiento antirretroviral, de 195 personas con VIH en el Instituto para el Desarrollo Humano, se realizó análisis bivariado para la obtención de datos. Resultados: La seroprevalencia obtenida para hepatitis B es de 7,7% y hepatitis C de 0,5%; la coinfección entre VIH y hepatitis B es de 80% con esquema antirretroviral tenofovir/lamivudina. El grupo poblacional homosexual tiene un riesgo de 5,5 veces más de tener la co-infección de VIH y hepatitis B con un valor de p de 0,006; con relación a la inmunización para hepatitis B solo el 9,2% de los pacientes cuentan con el esquema completo. Conclusión: Es imperativo ofertar las pruebas para hepatitis B y C a todas las personas con VIH; haciendo énfasis en los grupos más vulnerables (homosexuales); es importante el abastecimiento de dosis para la inmunización completa contra la hepatitis B en todos los servicios de salud públicos del país.
Keywords	VIH ; Hepatitis B ; Hepatitis C ; Tenofovir ; Lamivudina ; Medicine (General) ; R5-920
Language	Spanish
Publishing date	2021-10-01T00:00:00Z
Publisher	Universidad Mayor de San Simón, Facultad de Medicina
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Prediction of the potential biological activity of novel spiropyrazolo[3,4-b]pyridines and spiropyrazolo[3,4-b]pyridine-5,5'-pyrimidines by a ligand-protein inverse-docking approach.

Mejía-Gutiérrez, M / Olivero-Verbel, J / Quiroga, J / Romo, P / Castaño, S / Fierro, L

Journal of molecular graphics & modelling

2020 Volume 97, Page(s) 107581

Abstract: The interaction of a series of spiropyrazolo[3,4-b]pyridines and spiropyrazolo[3,4-b]pyridine-5,5' ...

Abstract	The interaction of a series of spiropyrazolo[3,4-b]pyridines and spiropyrazolo[3,4-b]pyridine-5,5'-pyrimidines with 975 molecular targets involved in different diseases and biochemical alterations in humans was assessed. In-silico and in-vivo methods were used to predict the potential biological activity of these compounds. The exposure of several individuals of C. elegans to these compounds shows that their lethality would be less than 10% and that they do not induce any alteration in their locomotion. The compounds identified as PRV-8 and 13-G were the most bioactive, and also showed other advantages such as; better structural properties, adequate pharmacokinetic and pharmacodynamic properties, and good flexibility and unsaturation, which placed them as the compounds of greatest interest to be tested in-vitro and in-vivo. The series of compounds described here exhibited significant interactions with the estrogen signaling pathway.
MeSH term(s)	Animals ; Antineoplastic Agents/pharmacology ; Caenorhabditis elegans ; Humans ; Ligands ; Molecular Docking Simulation ; Pyridines/pharmacology ; Pyrimidines/pharmacology ; Structure-Activity Relationship
Chemical Substances	Antineoplastic Agents ; Ligands ; Pyridines ; Pyrimidines ; pyridine (NH9L3PP67S)
Language	English
Publishing date	2020-03-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	1396450-1
ISSN	1873-4243 ; 1093-3263
ISSN (online)	1873-4243
ISSN	1093-3263
DOI	10.1016/j.jmgm.2020.107581
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3491: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: New Records of Anopheles benarrochi B (Diptera: Culicidae) in Malaria Hotspots in the Amazon Regions of Ecuador and Peru.

Morales Viteri, Diego / Herrera-Varela, Manuela / Albuja, Maribel / Quiroga, Cristina / Diaz, Gloria / Del Aguila Morante, Clara / Ramirez, Dario / Vinetz, Joseph M / Bickersmith, Sara A / Conn, Jan E

Journal of medical entomology

2020 Volume 58, Issue 3, Page(s) 1234–1240

Abstract: ... in the final analysis. Haplotypes from the present study plus An. benarrochi B GenBank sequences grouped ... study specimens were An. benarrochi B. Our findings confirm the presence of An. benarrochi B in Ecuador ... is An. benarrochi B, and we observed that it is highly anthropophilic. Overall, the known ...

Abstract	The increase in malaria transmission in the Amazon region motivated vector control units of the Ministry of Health of Ecuador and Peru to investigate Anopheles (Diptera: Culicidae) species present in transmission hotspots. Mosquitoes were collected using prokopack aspirators and CDC light traps (Ecuador) and human landing catch in Peru. In Ecuador, 84 Anopheles were captured from Pastaza, Morona Santiago, and Orellana provinces and identified morphologically [An. (An.) apicimacula Dyar and Knab, An. (Nys.) near benarrochi, An. (Nys.) near oswaldoi, An. (Nys.) near strodei, An. (An.) nimbus (Theobald, 1902), and An. (Nyssorhynchus) sp.]. In Peru, 1,150 Anopheles were collected in Andoas District. A subsample of 166 specimens was stored under silica and identified as An. near oswaldoi, An. darlingi, and An. (An.) mattogrossensis Lutz and Neiva. COI barcode region sequences were obtained for 137 adults (107 from Peru, 30 from Ecuador) identified by ITS2 PCR-RFLP as An. benarrochi Gabaldon, Cova Garcia, and Lopez and retained in the final analysis. Haplotypes from the present study plus An. benarrochi B GenBank sequences grouped separately from Brazilian An. benarrochi GenBank sequences by 44 mutation steps, indicating that the present study specimens were An. benarrochi B. Our findings confirm the presence of An. benarrochi B in Ecuador and reported here for the first time from the Amazonian provinces of Orellana and Morona Santiago. Furthermore, we confirm that the species collected in Andoas District in the Datem del Maranon Province, Peru, is An. benarrochi B, and we observed that it is highly anthropophilic. Overall, the known distribution of An. benarrochi B has been extended and includes southern Colombia, much of Peru and eastern Ecuador.
MeSH term(s)	Animal Distribution ; Animals ; Anopheles/physiology ; Ecuador ; Malaria ; Mosquito Vectors/physiology ; Peru
Language	English
Publishing date	2020-12-22
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	410635-0
ISSN	1938-2928 ; 0022-2585
ISSN (online)	1938-2928
ISSN	0022-2585
DOI	10.1093/jme/tjaa293
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 303: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito