Article ; Online: Progression from palindromic rheumatism to rheumatoid arthritis after COVID-19 vaccination.
ARP rheumatology
2022 Volume 1, Issue 1, Page(s) 100–101
Abstract: Infections including COVID-19 infection are associated with immune overactivation and hyperinflammation, and cases of incident inflammatory arthritis after COVID-19 and other respiratory viral infections have been reported. Theoretical concerns of ... ...
Title translation | Progression from palindromic rheumatism to rheumatoid arthritis after COVID-19 vaccination. |
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Abstract | Infections including COVID-19 infection are associated with immune overactivation and hyperinflammation, and cases of incident inflammatory arthritis after COVID-19 and other respiratory viral infections have been reported. Theoretical concerns of autoimmunity due to molecular mimicry exist with vaccines including vaccines for COVID-19, and rare cases of flares of underlying chronic inflammatory disorders such as systemic lupus erythematosus have been reported after COVID-19 vaccination. Here we present the case of a patient with a 7-year history of well-controlled palindromic rheumatism who developed rheumatoid arthritis 2 weeks after vaccination for COVID-19. This is the first such case to our knowledge, and further studies can elaborate on the risk of autoimmunity due to COVID-19 vaccines if one exists. Given the overall safety and efficacy of COVID-19 vaccines, the proven benefits of vaccinating vulnerable patients with autoimmune disorders outweigh this potential theoretical risk of autoimmune disease flare, and vaccinations in this at-risk population shall be strongly encouraged. |
MeSH term(s) | Arthritis, Rheumatoid ; Autoimmune Diseases/etiology ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Vaccination/adverse effects ; Vaccines |
Chemical Substances | COVID-19 Vaccines ; Vaccines |
Language | English |
Publishing date | 2022-05-21 |
Publishing country | Portugal |
Document type | Case Reports ; Journal Article |
ISSN | 2795-4552 |
ISSN (online) | 2795-4552 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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