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  1. Article ; Online: Climate change and the origin of SARS-CoV-2.

    Yan Yam, Esabelle Lo

    Journal of travel medicine

    2020  Volume 27, Issue 8

    MeSH term(s) Biodiversity ; COVID-19/epidemiology ; COVID-19/virology ; Climate Change ; Environment ; Humans ; Population Dynamics ; SARS-CoV-2 ; Travel ; Travel Medicine/methods ; Travel Medicine/trends
    Language English
    Publishing date 2020-12-03
    Publishing country England
    Document type Letter
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taaa224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 will further exacerbate global antimicrobial resistance.

    Yam, Esabelle Lo Yan

    Journal of travel medicine

    2020  Volume 27, Issue 6

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Antimicrobial Stewardship ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/drug therapy ; Drug Resistance, Bacterial ; Global Health ; Humans ; Pandemics ; Pneumonia, Viral/drug therapy ; SARS-CoV-2
    Chemical Substances Anti-Bacterial Agents
    Keywords covid19
    Language English
    Publishing date 2020-05-30
    Publishing country England
    Document type Letter
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taaa098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19 will further exacerbate global antimicrobial resistance

    Yam, Esabelle Lo Yan

    Journal of Travel Medicine

    2020  Volume 27, Issue 6

    Keywords General Medicine ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taaa098
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: i-MoMCARE

    Chan Hang Saing / Mengieng Ung / Sovanthida Suy / Sreymom Oy / Chhavarath Dary / Esabelle Lo Yan Yam / Sophea Chhorn / Michiko Nagashima-Hayashi / Dyna Khuon / Sovatha Mam / Rattana Kim / Vonthanak Saphonn / Siyan Yi

    Trials, Vol 24, Iss 1, Pp 1-

    Innovative Mobile Technology for Maternal and Child Health Care in Cambodia—study protocol of a cluster randomized controlled trial

    2023  Volume 19

    Abstract: Abstract Background The Government of Cambodia established the village health support groups (VHSGs) in 2003 to facilitate primary healthcare activities, including maternal and child health (MCH) services. However, VHSGs face several challenges that ... ...

    Abstract Abstract Background The Government of Cambodia established the village health support groups (VHSGs) in 2003 to facilitate primary healthcare activities, including maternal and child health (MCH) services. However, VHSGs face several challenges that hinder them from performing optimally, including a lack of regular structured training and remuneration and limited and inconsistent support and supervision from the health centers (HCs). This implementation research aims to develop, implement, and evaluate a digital health intervention to improve the performance of VHSGs through better support and supervision and increase the MCH service coverage in rural Cambodia. Methods i-MoMCARE, a two-arm cluster randomized controlled trial, will be conducted between 2022 and 2025. Five operational districts (ODs) have been randomized to an intervention arm and the other five ODs to the control arm. The intervention will last for 24 months. Around 200 VHSGs in the intervention arm will be equipped with a mobile application as a job aid and 20 HC staff with a web interface to improve support and supervision of VHSGs. The potential beneficiaries will include pregnant women, mothers, and children under 2 years old. We will measure the outcomes at baseline and endline. The primary outcomes will consist of a composite MCH index constructed from maternal and newborn care indicators, child immunization, and treatment of under-two children. Secondary outcomes will include coverage of selected MCH services. We will conduct the intention-to-treat and per-protocol analyses. We will conduct qualitative interviews with selected beneficiaries and stakeholders to evaluate the intervention’s acceptability, feasibility, and scalability. We will also conduct a cost-effective analysis using decision-analytic modeling incorporating a societal perspective that explores different time horizons, intervention effects, and when scaled up to the national level. Discussion i-MoMCARE is expected to increase MCH service access and coverage in rural ...
    Keywords Community health workers ; Digital health intervention ; Maternal and child health ; Implementation research ; Low- and middle-income country ; Asia ; Medicine (General) ; R5-920
    Subject code 360
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: i-MoMCARE: Innovative Mobile Technology for Maternal and Child Health Care in Cambodia-study protocol of a cluster randomized controlled trial.

    Saing, Chan Hang / Ung, Mengieng / Suy, Sovanthida / Oy, Sreymom / Dary, Chhavarath / Yam, Esabelle Lo Yan / Chhorn, Sophea / Nagashima-Hayashi, Michiko / Khuon, Dyna / Mam, Sovatha / Kim, Rattana / Saphonn, Vonthanak / Yi, Siyan

    Trials

    2023  Volume 24, Issue 1, Page(s) 692

    Abstract: Background: The Government of Cambodia established the village health support groups (VHSGs) in 2003 to facilitate primary healthcare activities, including maternal and child health (MCH) services. However, VHSGs face several challenges that hinder them ...

    Abstract Background: The Government of Cambodia established the village health support groups (VHSGs) in 2003 to facilitate primary healthcare activities, including maternal and child health (MCH) services. However, VHSGs face several challenges that hinder them from performing optimally, including a lack of regular structured training and remuneration and limited and inconsistent support and supervision from the health centers (HCs). This implementation research aims to develop, implement, and evaluate a digital health intervention to improve the performance of VHSGs through better support and supervision and increase the MCH service coverage in rural Cambodia.
    Methods: i-MoMCARE, a two-arm cluster randomized controlled trial, will be conducted between 2022 and 2025. Five operational districts (ODs) have been randomized to an intervention arm and the other five ODs to the control arm. The intervention will last for 24 months. Around 200 VHSGs in the intervention arm will be equipped with a mobile application as a job aid and 20 HC staff with a web interface to improve support and supervision of VHSGs. The potential beneficiaries will include pregnant women, mothers, and children under 2 years old. We will measure the outcomes at baseline and endline. The primary outcomes will consist of a composite MCH index constructed from maternal and newborn care indicators, child immunization, and treatment of under-two children. Secondary outcomes will include coverage of selected MCH services. We will conduct the intention-to-treat and per-protocol analyses. We will conduct qualitative interviews with selected beneficiaries and stakeholders to evaluate the intervention's acceptability, feasibility, and scalability. We will also conduct a cost-effective analysis using decision-analytic modeling incorporating a societal perspective that explores different time horizons, intervention effects, and when scaled up to the national level.
    Discussion: i-MoMCARE is expected to increase MCH service access and coverage in rural Cambodia. It will contribute to advancing digital health use in primary healthcare interventions, which remains in its infancy in the country. Furthermore, the study findings will be a valuable addition to a growing body of literature on the effectiveness and feasibility of mobile health to improve coverage of MCH services in rural low- and middle-income country settings.
    Trial registration: ClinicalTrial.gov NCT05639595. Registered on 06 December 2022.
    MeSH term(s) Female ; Humans ; Infant ; Infant, Newborn ; Pregnancy ; Cambodia ; Randomized Controlled Trials as Topic ; Maternal-Child Health Services ; Mobile Applications
    Language English
    Publishing date 2023-10-26
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-023-07724-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Antimicrobial Resistance in the Asia Pacific region: a meeting report.

    Yam, Esabelle Lo Yan / Hsu, Li Yang / Yap, Eric Peng-Huat / Yeo, Tsin Wen / Lee, Vernon / Schlundt, Joergen / Lwin, May O / Limmathurotsakul, Direk / Jit, Mark / Dedon, Peter / Turner, Paul / Wilder-Smith, Annelies

    Antimicrobial resistance and infection control

    2019  Volume 8, Page(s) 202

    Abstract: The Asia Pacific region, home to two-thirds of the world's population and ten of the least developed countries, is considered a regional hot-spot for the emergence and spread of antimicrobial resistance (AMR). Despite this, there is a dearth of high- ... ...

    Abstract The Asia Pacific region, home to two-thirds of the world's population and ten of the least developed countries, is considered a regional hot-spot for the emergence and spread of antimicrobial resistance (AMR). Despite this, there is a dearth of high-quality regional data on the extent of AMR. Recognising the urgency to close this gap, Singapore organised a meeting to discuss the problems in the region and frame a call for action. Representatives from across the region and beyond attended the meeting on the "Antimicrobial Resistance in the Asia Pacific & its impact on Singapore" held in November 2018. This meeting report is a summary of the discussions on the challenges and progress in surveillance, drivers and levers of AMR emergence, and the promising innovations and technologies that could be used to combat the increasing threat of AMR in the region. Enhanced surveillance and research to provide improved evidence-based strategies and policies are needed. The major themes that emerged for an action plan are working towards a tailored solution for the region by harnessing the One Health approach, enhancing inter-country collaborations, and collaboratively leverage upon new emerging technologies. A regionally coordinated effort that is target-driven, sustainable and builds on a framework facilitating communication and governance will strengthen the fight against AMR in the Asia Pacific region.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Asia ; Bacteria/drug effects ; Congresses as Topic ; Developing Countries ; Drug Resistance, Bacterial ; Humans ; One Health ; Singapore
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2019-12-18
    Publishing country England
    Document type Congress ; Research Support, Non-U.S. Gov't
    ZDB-ID 2666706-X
    ISSN 2047-2994 ; 2047-2994
    ISSN (online) 2047-2994
    ISSN 2047-2994
    DOI 10.1186/s13756-019-0654-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Strengthening national capacities for pandemic preparedness: a cross-country analysis of COVID-19 cases and deaths.

    Duong, David B / King, Andrew J / Grépin, Karen A / Hsu, Li Yang / Lim, Jeremy Fy / Phillips, Christine / Thai, Truc Thanh / Venkatachalam, Indumathi / Vogt, Florian / Yam, Esabelle Lo Yan / Bazley, Stephanie / Chang, Lydia Dai-Jia / Flaugh, Rachel / Nagle, Baily / Ponniah, Johanan Dravium / Sun, Penny / Trad, Nicolas K / Berwick, Donald M

    Health policy and planning

    2021  Volume 37, Issue 1, Page(s) 55–64

    Abstract: The International Health Regulations-State Party Annual Reporting (IHR-SPAR) index and the Global Health Security Index (GHSI) have been developed to aid in strengthening national capacities for pandemic preparedness. We examined the relationship between ...

    Abstract The International Health Regulations-State Party Annual Reporting (IHR-SPAR) index and the Global Health Security Index (GHSI) have been developed to aid in strengthening national capacities for pandemic preparedness. We examined the relationship between country-level rankings on these two indices, along with two additional indices (the Universal Health Coverage Service Coverage Index and World Bank Worldwide Governance Indicator (n = 195)) and compared them to the country-level reported coronavirus disease (COVID-19) cases and deaths (Johns Hopkins University COVID-19 Dashboard) through 17 June 2020. Ordinary least squares regression models were used to compare weekly reported COVID-19 cases and death rates per million in the first 12 weeks of the pandemic between countries classified as low, middle and high ranking on each index while controlling for country socio-demographic information. Countries with higher GHSI and IHR-SPAR index scores experienced fewer reported COVID-19 cases and deaths but only for the first 8 weeks after the country's first case. For the GHSI, this association was further limited to countries with populations below 69.4 million. For both the GHSI and IHR-SPAR, countries with a higher sub-index score in human resources for pandemic preparedness reported fewer COVID-19 cases and deaths in the first 8 weeks after the country's first reported case. The Universal Health Coverage Service Coverage Index and Worldwide Governance Indicator country-level rankings were not associated with COVID-19 outcomes. The associations between GHSI and IHR-SPAR scores and COVID-19 outcomes observed in this study demonstrate that these two indices, although imperfect, may have value, especially in countries with a population under 69.4 million people for the GHSI. Preparedness indices may have value; however, they should continue to be evaluated as policy makers seek to better prepare for future global public health crises.
    MeSH term(s) COVID-19 ; Global Health ; Humans ; Pandemics/prevention & control ; Public Health ; SARS-CoV-2
    Language English
    Publishing date 2021-10-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 632896-9
    ISSN 1460-2237 ; 0268-1080
    ISSN (online) 1460-2237
    ISSN 0268-1080
    DOI 10.1093/heapol/czab122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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