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  1. Book: The AST handbook of transplant infections

    Kumar, Deepali / Humar, Atul

    2011  

    Title variant Handbook of transplant infections
    Institution American Society of Transplantation
    Author's details ed. by Deepali Kumar ; Atul Humar
    Keywords Transplants / adverse effects ; Virus Diseases / therapy ; Bacterial Infections / therapy ; Mycoses / therapy
    Language English
    Size XV, 171 S. : Ill., 25 cm
    Publisher Wiley-Blackwell
    Publishing place Chichester
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT016993699
    ISBN 978-0-470-65827-7 ; 0-470-65827-4 ; 9781444397925 ; 9781444397932 ; 9781444397949 ; 1444397923 ; 1444397931 ; 144439794X
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: SARS-CoV-2 mRNA vaccine: Sometimes life needs a boost.

    Lo, Carson Ka-Lok / Kumar, Deepali

    Transplant infectious disease : an official journal of the Transplantation Society

    2023  Volume 25, Issue 5, Page(s) e14135

    MeSH term(s) Humans ; COVID-19 Vaccines ; SARS-CoV-2/genetics ; COVID-19/prevention & control ; Antibodies, Viral ; Vaccination ; mRNA Vaccines
    Chemical Substances COVID-19 Vaccines ; Antibodies, Viral
    Language English
    Publishing date 2023-08-24
    Publishing country Denmark
    Document type Editorial
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.14135
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  3. Article ; Online: Respiratory viral infections including COVID-19 in solid organ transplantation.

    Lo, Carson K L / Kumar, Deepali

    Current opinion in organ transplantation

    2023  Volume 28, Issue 6, Page(s) 471–482

    Abstract: Purpose of review: Respiratory viral infections are prevalent and contribute to significant morbidity and mortality among solid organ transplant (SOT) recipients. We review updates from literature on respiratory viruses, including severe acute ... ...

    Abstract Purpose of review: Respiratory viral infections are prevalent and contribute to significant morbidity and mortality among solid organ transplant (SOT) recipients. We review updates from literature on respiratory viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in the SOT recipient.
    Recent findings: With the wider availability and use of molecular diagnostic tests, our understanding of the epidemiology and impact of respiratory viruses in the SOT population continues to expand. While considerable attention has been given to the coronavirus disease 2019 (COVID-19) pandemic, the advances in prevention and treatment strategies of SARS-CoV-2 offered valuable insights into the development of new therapeutic options for managing other respiratory viruses in both the general and SOT population.
    Summary: Respiratory viruses can present with a diverse range of symptoms in SOT recipients, with potentially associated acute rejection and chronic lung allograft dysfunction in lung transplant recipients. The epidemiology, clinical presentations, diagnostic approaches, and treatment and preventive strategies for clinically significant RNA and DNA respiratory viruses in SOT recipients are reviewed. This review also covers novel antivirals, immunologic therapies, and vaccines in development for various community-acquired respiratory viruses.
    MeSH term(s) Humans ; COVID-19/epidemiology ; SARS-CoV-2 ; Organ Transplantation/adverse effects ; Transplantation, Homologous ; Transplant Recipients
    Language English
    Publishing date 2023-09-26
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1390429-2
    ISSN 1531-7013 ; 1087-2418
    ISSN (online) 1531-7013
    ISSN 1087-2418
    DOI 10.1097/MOT.0000000000001106
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  4. Article ; Online: C4 article

    Kumar, Deepali

    American Journal of Transplantation ; ISSN 1600-6135 1600-6143

    Implications of COVID‐19 in transplantation

    2020  

    Keywords Immunology and Allergy ; Pharmacology (medical) ; Transplantation ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/ajt.16346
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Naringenin ameliorates aluminum toxicity-induced testicular dysfunctions in mice by suppressing oxidative stress and histopathological alterations.

    Rai, Ravina / Jat, Deepali / Mishra, Siddhartha Kumar

    Systems biology in reproductive medicine

    2023  Volume 69, Issue 5, Page(s) 347–353

    Abstract: Environmental aluminum intoxication has shown increasingly alarming negative consequences on reproductive health. This needs mechanistic exploration and preventive management using medicines like herbal supplementation. The ameliorative effects of ... ...

    Abstract Environmental aluminum intoxication has shown increasingly alarming negative consequences on reproductive health. This needs mechanistic exploration and preventive management using medicines like herbal supplementation. The ameliorative effects of naringenin (NAR) against AlCl
    MeSH term(s) Male ; Mice ; Animals ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Aluminum/toxicity ; Aluminum/metabolism ; Oxidative Stress ; Testis/metabolism ; Body Weight
    Chemical Substances Antioxidants ; Aluminum (CPD4NFA903) ; naringenin (HN5425SBF2)
    Language English
    Publishing date 2023-05-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2417234-0
    ISSN 1939-6376 ; 1939-6368
    ISSN (online) 1939-6376
    ISSN 1939-6368
    DOI 10.1080/19396368.2023.2203794
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  6. Article ; Online: Response to Correspondence on Outcomes of COVID-19 in Unvaccinated Compared With Vaccinated Solid Organ Transplant Recipients.

    Hall, Victoria G / Humar, Atul / Kumar, Deepali

    Transplantation

    2022  Volume 106, Issue 10, Page(s) e462

    MeSH term(s) COVID-19/prevention & control ; Humans ; Organ Transplantation/adverse effects ; SARS-CoV-2 ; Transplant Recipients
    Language English
    Publishing date 2022-07-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004253
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    Zs.MO 509: Show issues

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  7. Article ; Online: 30G needle aspiration - A modified technique of capsulorhexis in pediatric cataract with high intra-lenticular pressure.

    Singhal, Deepali / Narde, Harpreet Kaur / Maharana, Prafulla Kumar

    Indian journal of ophthalmology

    2023  Volume 71, Issue 5, Page(s) 2237–2239

    Abstract: This surgical technique describes a modification of the continuous curvilinear capsulorhexis (CCC) to achieve an adequate-sized capsulorhexis in pediatric cataracts with high intralenticular pressure. Performing CCC in pediatric cataracts is challenging, ...

    Abstract This surgical technique describes a modification of the continuous curvilinear capsulorhexis (CCC) to achieve an adequate-sized capsulorhexis in pediatric cataracts with high intralenticular pressure. Performing CCC in pediatric cataracts is challenging, especially when the intralenticular pressure is high. This technique involves 30 G needle decompression of the lens to reduce positive intralenticular pressure and subsequent flattening of the anterior capsule. This minimizes the chances of extension of CCC without using any special equipment. This technique was used in two eyes of two patients (age 8 and 10 years) with unilateral developmental cataracts. Both surgeries were performed by a single surgeon (PKM). In both eyes, a well-centered CCC was achieved with no extension, and a posterior chamber intraocular lens (IOL) was placed in the capsular bag. Thus, our technique of 30 G needle aspiration could be extremely useful to achieve an adequately sized CCC in pediatric cataracts with high intralenticular pressure, especially for beginner surgeons.
    MeSH term(s) Humans ; Child ; Capsulorhexis/methods ; Lens Capsule, Crystalline/surgery ; Lens Implantation, Intraocular/methods ; Phacoemulsification/methods ; Cataract/complications
    Language English
    Publishing date 2023-05-18
    Publishing country India
    Document type Journal Article
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_1276_22
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    Zs.MO 598: Show issues

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  8. Article: Nutritional characteristics of

    Chaudhary, Mridul Kant / Tripathi, Deepali / Misra, Ankita / Singh, Satyendra Pratap / Srivastava, Pankaj Kumar / Gupta, Vartika / Acharya, Rabinarayan / Srivastava, Sharad

    Heliyon

    2024  Volume 10, Issue 2, Page(s) e24193

    Abstract: Malnutrition and hunger is a serious global issue, however, wild fruits possess the potential of combatting it being rich in nutrients. ...

    Abstract Malnutrition and hunger is a serious global issue, however, wild fruits possess the potential of combatting it being rich in nutrients.
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24193
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  9. Article ; Online: High-risk pregnancy in India: Prevalence and contributing risk factors - a national survey-based analysis.

    Kuppusamy, Periyasamy / Prusty, Ranjan Kumar / Kale, Deepali Prakash

    Journal of global health

    2023  Volume 13, Page(s) 4116

    Abstract: Background: High-risk pregnancies (HRP) place women and their offspring at the highest risk for morbidity and mortality. Maternal and medical risks increase pregnancy risk and complications during pregnancy and childbirth. Here, we reported the current ... ...

    Abstract Background: High-risk pregnancies (HRP) place women and their offspring at the highest risk for morbidity and mortality. Maternal and medical risks increase pregnancy risk and complications during pregnancy and childbirth. Here, we reported the current prevalence of high-risk pregnancies among Indian women, which is defined through various factors such as maternal, lifestyle, medical, current health risk and adverse birth outcomes.
    Methods: This is a cross-sectional study based on secondary data from India's National Family Health Survey-5 (NFHS-5). A total of 23 853 currently pregnant women were considered for analysis after considering the inclusion and exclusion criteria. The prevalence and contributing factors of high-risk pregnancies were estimated using descriptive statistics and logistic regression, respectively.
    Results: The prevalence of high-risk pregnancies among Indian women was 49.4%, with 33% of women having a single high-risk, and 16.4% having multiple high-risk pregnancies. Notably, pregnant women from Meghalaya and Manipur states had 67.8% and 66.7% with one or more high-risk factors, respectively. About 31.1% of women had short birth spacing, and 19.5% of women had adverse birth outcomes during the last birth. Logistic regression analysis showed that women with no education (adjusted odds ratio (AOR) = 2.02; 95% confidence interval (CI) = 1.84-2.22) and the poorest wealth quintile (AOR = 1.33; 95% CI = 1.04-1.29) had significantly higher odds of having HRP than those with higher education and the highest wealth quintile, respectively.
    Conclusions: Nearly half of all pregnancies in India have one or more high-risk factors, which is a matter of concern, and the risks were higher among the vulnerable population such as no educated, poorest groups etc. The leading high-risk factors such as short-birth spacing, adverse birth outcomes, and caesarean deliveries should be addressed through the health policy and programmes.
    MeSH term(s) Pregnancy ; Female ; Humans ; Pregnancy, High-Risk ; Prevalence ; Cross-Sectional Studies ; India/epidemiology ; Pregnancy Complications/epidemiology
    Language English
    Publishing date 2023-09-15
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2741629-X
    ISSN 2047-2986 ; 2047-2986
    ISSN (online) 2047-2986
    ISSN 2047-2986
    DOI 10.7189/jogh.13.04116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A comprehensive review on role of Aurora kinase inhibitors (AKIs) in cancer therapeutics.

    Gupta, Deepali / Kumar, Mukesh / Saifi, Sana / Rawat, Shivani / Ethayathulla, A S / Kaur, Punit

    International journal of biological macromolecules

    2024  Volume 265, Issue Pt 2, Page(s) 130913

    Abstract: Aurora kinases (AURKs) are a family of serine /threonine protein kinases that have a crucial role in cell cycle process mainly in the event of chromosomal segregation, centrosome maturation and cytokinesis. The family consists of three members including ... ...

    Abstract Aurora kinases (AURKs) are a family of serine /threonine protein kinases that have a crucial role in cell cycle process mainly in the event of chromosomal segregation, centrosome maturation and cytokinesis. The family consists of three members including Aurora kinase A (AURK-A), Aurora kinase B (AURK-B) and Aurora kinase C (AURK-C). All AURKs contain a conserved kinase domain for their activity but differ in their cellular localization and functions. AURK-A and AURK-B are expressed mainly in somatic cells while the expression of AURK-C is limited to germ cells. AURK-A promotes G2 to M transition of cell cycle by controlling centrosome maturation and mitotic spindle assembly. AURK-B and AURK-C form the chromosome passenger complex (CPC) that ensures proper chromosomal alignments and segregation. Aberrant expression of AURK-A and AURK-B has been detected in several solid tumours and malignancies. Hence, they have become an attractive therapeutic target against cancer. The first part of this review focuses on AURKs structure, functions, subcellular localization, and their role in tumorigenesis. The review also highlights the functional and clinical impact of selective as well as pan kinase inhibitors. Currently, >60 compounds that target AURKs are in preclinical and clinical studies. The drawbacks of existing inhibitors like selectivity, drug resistance and toxicity have also been addressed. Since, majority of inhibitors are Aurora kinase inhibitor (AKI) type-1 that bind to the active (DFG
    MeSH term(s) Humans ; Protein Serine-Threonine Kinases/metabolism ; Cell Division ; Cell Cycle Proteins/genetics ; Chromosome Segregation ; Neoplasms/drug therapy ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use
    Chemical Substances Protein Serine-Threonine Kinases (EC 2.7.11.1) ; Cell Cycle Proteins ; Protein Kinase Inhibitors
    Language English
    Publishing date 2024-03-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.130913
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