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  1. Article: Vaping associated spontaneous pneumothorax - A case series of an enigmatic entity!

    Ashraf, Obaid / Nasrullah, Adeel / Karna, Rahul / Alhajhusain, Ahmad

    Respiratory medicine case reports

    2021  Volume 34, Page(s) 101535

    Abstract: The use of electronic nicotine delivery devices (ENDDs) has risen to an epidemic level among high schoolers and people aged 18-34. To our knowledge there are only 7 reported cases of spontaneous pneumothorax (SP-PTX) associated with vaping, and herein we ...

    Abstract The use of electronic nicotine delivery devices (ENDDs) has risen to an epidemic level among high schoolers and people aged 18-34. To our knowledge there are only 7 reported cases of spontaneous pneumothorax (SP-PTX) associated with vaping, and herein we describe 4 additional cases. We propose identifying this disease process as a novel entity, Vaping-Associated Spontaneous Pneumothorax (VASP). VASP requires early interventional treatment and has a high recurrence rate, and we suggest that vaping cessation and early interventional treatment including tube thoracostomy and surgical treatment is necessary in most cases to prevent recurrences.
    Language English
    Publishing date 2021-10-23
    Publishing country England
    Document type Case Reports
    ZDB-ID 2666110-X
    ISSN 2213-0071
    ISSN 2213-0071
    DOI 10.1016/j.rmcr.2021.101535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Nontraumatic Neurosurgical Emergencies.

    Ashraf, Obaid / Bajwa, Omer / Leonardo, Jody / Altenbaugh, Mary

    Critical care nursing quarterly

    2021  Volume 46, Issue 1, Page(s) 2–16

    Abstract: Most neurosurgical emergencies involve management of intracranial pressure, decompression of brain parenchyma, or diversion of cerebrospinal fluid. These interventions aim to prevent progression and reverse damage to neural structures. The pathologies ... ...

    Abstract Most neurosurgical emergencies involve management of intracranial pressure, decompression of brain parenchyma, or diversion of cerebrospinal fluid. These interventions aim to prevent progression and reverse damage to neural structures. The pathologies that require emergent treatment either develop acutely or may progress over days until they reach a critical point causing decompensation. The risk of any intervention need to be weighed against potential benefits and should involve discussions with the family. Interventions have shown to be effective and facilitate patients' return to improved functionality. However, while neurosurgical interventions are lifesaving, surviving patients may have a severe residual disability. This article presents an overview of commonly seen nontraumatic neurosurgical emergencies. Each section presents key facets of presentation, initial workup, management, and role of surgical intervention.
    MeSH term(s) Humans ; Emergencies ; Neurosurgical Procedures
    Language English
    Publishing date 2021-12-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639095-x
    ISSN 1550-5111 ; 0887-9303
    ISSN (online) 1550-5111
    ISSN 0887-9303
    DOI 10.1097/CNQ.0000000000000434
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Possible role of COVID-19 in the relapse of Klein-Levin Syndrome.

    Nasrullah, Adeel / Javed, Anam / Ashraf, Obaid / Malik, Khalid

    Respiratory medicine case reports

    2021  Volume 33, Page(s) 101445

    Abstract: Klein-Levin Syndrome (KLS) is an extremely rare neurological disorder which can manifest as recurring spells of sleepiness, cognitive disturbances and behavioral changes. We present a novel case of KLS relapse in the setting of Coronavirus disease-19 ( ... ...

    Abstract Klein-Levin Syndrome (KLS) is an extremely rare neurological disorder which can manifest as recurring spells of sleepiness, cognitive disturbances and behavioral changes. We present a novel case of KLS relapse in the setting of Coronavirus disease-19 (COVID-19). A 36-year-old male who had a known history of KLS since adolescence was admitted with sleepiness and behavioral disturbances. Brain imaging and autoimmune encephalitis work was unremarkable. The patient was diagnosed with a relapse of KLS secondary to COVID-19 based on symptomology and lack of any other precipitating factor. The patient required 8 days of hospitalization and was treated with benzodiazepines due to a history of robust response to lorazepam during a prior episode. The patient progressively improved and was discharged home on lorazepam taper. We report that similar to other neurotropic viruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be the culprit in instigating KLS relapse.
    Language English
    Publishing date 2021-05-29
    Publishing country England
    Document type Case Reports
    ZDB-ID 2666110-X
    ISSN 2213-0071
    ISSN 2213-0071
    DOI 10.1016/j.rmcr.2021.101445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: In Vitro Anticancer and Antibacterial Activities of the Essential Oil of Forsskal's Basil Growing in Extreme Environmental Conditions.

    Bader, Ammar / Abdalla, Ashraf N / Obaid, Najla A / Youssef, Lamees / Naffadi, Hind M / Elzubier, Mohamed E / Almaimani, Riyad A / Flamini, Guido / Pieracci, Ylenia / El-Readi, Mahmoud Zaki

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 3

    Abstract: Many species belonging to the ... ...

    Abstract Many species belonging to the genus
    Language English
    Publishing date 2023-02-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13030651
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Evaluation of 2,3-Dihydro-1,5-benzothiazepine Derivatives as Potential Tyrosinase Inhibitors:

    Al-Rooqi, Munirah M / Sadiq, Amina / Obaid, Rami J / Ashraf, Zaman / Nazir, Yasir / Jassas, Rabab S / Naeem, Nafeesa / Alsharif, Meshari A / Shah, Syed Wadud Ali / Moussa, Ziad / Mughal, Ehsan Ullah / Farghaly, Abdel-Rahman / Ahmed, Saleh A

    ACS omega

    2023  Volume 8, Issue 19, Page(s) 17195–17208

    Abstract: Benzothiazepines are pharmacologically active compounds, frequently utilized as a precursor for acquiring versatile molecules with several bioactivities including anti-inflammatory, anti-human immunodeficiency virus (anti-HIV), analgesic, antitumor, ... ...

    Abstract Benzothiazepines are pharmacologically active compounds, frequently utilized as a precursor for acquiring versatile molecules with several bioactivities including anti-inflammatory, anti-human immunodeficiency virus (anti-HIV), analgesic, antitumor, antimicrobial, and antitubercular. In this study, the 2,4-diphenyl-2,3-dihydro-1,5-benzothiazepine scaffold was selected for their
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c01566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Surgical Emergencies in the ICU.

    Saini, Vikram / Ashraf, Obaid / Babowice, James / Hamilton, Holly A / Khan, Uzer / Bhanot, Nitin

    Critical care nursing quarterly

    2022  Volume 46, Issue 1, Page(s) 48–65

    Abstract: Surgical emergencies are common in the critical care setting and require prompt diagnosis and management. Here, we discuss some of the surgical emergencies involving the gastrointestinal, hepatobiliary, and genitourinary sites. In addition, foreign body ... ...

    Abstract Surgical emergencies are common in the critical care setting and require prompt diagnosis and management. Here, we discuss some of the surgical emergencies involving the gastrointestinal, hepatobiliary, and genitourinary sites. In addition, foreign body aspiration and necrotizing soft-tissue infections have been elaborated. Clinicians should be aware of the risk factors, keys examination findings, diagnostic modalities, and medical as well as surgical treatment options for these potentially fatal illnesses.
    MeSH term(s) Humans ; Emergencies ; Risk Factors ; Intensive Care Units
    Language English
    Publishing date 2022-11-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639095-x
    ISSN 1550-5111 ; 0887-9303
    ISSN (online) 1550-5111
    ISSN 0887-9303
    DOI 10.1097/CNQ.0000000000000437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Qualitative And Quantitative Magnetic Resonance Imaging Assessment Of Focal Liver Lesions

    Obaid Ashraf / Choh Naseer / Shah Omair

    Journal of Research in Clinical Medicine, Vol 9, Iss 1, Pp 27-

    A Study To Evaluate The Role Of Different MRI Sequences.

    2021  Volume 27

    Abstract: Background: Focal liver lesions have a broad differential diagnosis. MRI with its improved soft tissue characterization and newer sequences can significantly narrow the differentials especially when discriminating benign from malignant lesions. Methods: ... ...

    Abstract Background: Focal liver lesions have a broad differential diagnosis. MRI with its improved soft tissue characterization and newer sequences can significantly narrow the differentials especially when discriminating benign from malignant lesions. Methods: T1, T1 IN AND OUT OF PHASE, T2, LONG TE T2 AND Diffusion Weighted Imaging was done in 159 patients with USG documented focal liver lesion. Qualitative and quantitative assessment of ADC values and long TE images was done and a threshold for differentiating benign from malignant lesions was obtained. The MRI diagnosis was compared with final diagnosis obtained from histopathology in most cases or follow up and other tests (markers and RBC scan) were histopathology was not available. Sensitivity, specificity and accuracy of MRI sequences in differentiating various focal lesions were obtained. Results: T1 weighted images were useful for identifying fat, hemorrhage and iron within the lesions. T2 weighted imaging was able to correctly classify 82.0% lesions as malignant and 83.7% lesions as benign. Long TE T2 images were highly accurate in distinguishing haemangiomas and cysts from solid lesions. On diffusion-weighted (DW) imaging, 89.5% (i.e. 60 out of 67) lesions were correctly classified as malignant and 88.0% (i.e. 81 out of 92) lesions were correctly classified as benign. Threshold ADC value of 1.37 × 10-3 mm2/s is highly accurate for differentiating malignant from benign lesions. Conclusion: DWI is a sine qua non in liver lesion assessment allowing improved detection and characterization. Long TE T2 weighted imaging can accurately detect haemangiomas and cysts and rule out metastasis.
    Keywords mri magnetic resonance imaging ; dwi diffusion weighted imaging ; usg ultrasonography ; adc apparent diffusion coefficient ; te time to echo ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Tabriz University of Medical Sciences Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Amidst COVID-19 pandemic: the catastrophic sequelae of an inadvertent carotid artery insertion during central venous catheter placement - a case report.

    Tanveer Ud Din, Mian / Nasrullah, Adeel / Sarma, Deeksha / Ashraf, Obaid / Arshad, Hammad

    Journal of community hospital internal medicine perspectives

    2021  Volume 11, Issue 5, Page(s) 689–692

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2021-09-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2616884-4
    ISSN 2000-9666
    ISSN 2000-9666
    DOI 10.1080/20009666.2021.1952015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cerebral hemiatrophy

    Suhail Rafiq / Musaib Ahmad Dar / Obaid Ashraf / Inayat Ellahi

    CHRISMED Journal of Health and Research, Vol 8, Iss 4, Pp 272-

    Case series of three cases

    2021  Volume 275

    Abstract: Pediatric cerebral hemiatrophy is a rare entity with widespread etiology. Imaging in form of computed tomography and magnetic resonance imaging is helpful in differentiating between the etiologies of hemiatrophy. We describe imaging findings in three ... ...

    Abstract Pediatric cerebral hemiatrophy is a rare entity with widespread etiology. Imaging in form of computed tomography and magnetic resonance imaging is helpful in differentiating between the etiologies of hemiatrophy. We describe imaging findings in three different cases of hemiatrophy due to Sturge-Weber syndrome, Dyke-Davidoff-Masson syndrome, and Rasmussen encephalitis.
    Keywords dyke-davidoff-masson syndrome ; hemiatrophy ; magnetic resonance imaging ; rasmussen encephalitis ; sturge-weber syndrome ; Medicine ; R ; Nursing ; RT1-120
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: COVID-19: An Update on the Epidemiological, Clinical, Preventive, and Therapeutic Management of 2019 Novel Coronavirus Disease.

    Ashraf, Obaid / Virani, Ahmed / Cheema, Tariq

    Critical care nursing quarterly

    2020  Volume 44, Issue 1, Page(s) 128–137

    Abstract: The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) remains a serious issue for global health, given widespread infectivity and a high contagion rate. A tremendous amount of data has been generated since it was ... ...

    Abstract The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) remains a serious issue for global health, given widespread infectivity and a high contagion rate. A tremendous amount of data has been generated since it was first identified in December 2019. It is vital to keep up with these data from across the world at a time of uncertainty and continuously evolving guidelines and clinical practice. This review provides an update on recent developments concerning epidemiology, clinical presentation, treatment options, and scientific advancements to combat the COVID-19 pandemic.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/physiopathology ; COVID-19/therapy ; Contact Tracing/methods ; Global Health/statistics & numerical data ; Humans ; Pandemics/prevention & control ; Preventive Medicine/methods ; SARS-CoV-2 ; United States/epidemiology
    Language English
    Publishing date 2020-11-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639095-x
    ISSN 1550-5111 ; 0887-9303
    ISSN (online) 1550-5111
    ISSN 0887-9303
    DOI 10.1097/CNQ.0000000000000346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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