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  1. Article: Guillain-Barré syndrome following the first dose of SARS-CoV-2 vaccine: A temporal occurrence, not a causal association.

    Ogbebor, Osakpolor / Seth, Harshit / Min, Zaw / Bhanot, Nitin

    IDCases

    2021  Volume 24, Page(s) e01143

    Abstract: Safety monitoring is of paramount importance for vaccines authorized for emergent use (EUA) by the US Food and Drug Administration (FDA) against SARS-CoV-2. Mass immunization is an essential tool to end the current pandemic, but vaccine surveillance is ... ...

    Abstract Safety monitoring is of paramount importance for vaccines authorized for emergent use (EUA) by the US Food and Drug Administration (FDA) against SARS-CoV-2. Mass immunization is an essential tool to end the current pandemic, but vaccine surveillance is necessary to identify any potentially associated harms. At the same time, probability of temporal bias should be borne in mind before making conclusions about causality between the vaccine and an attributable undesired effect. We report a case of Guillain-Barré syndrome after the first dose of SARS-CoV-2 vaccine and believe this is a temporal, rather than causal association.
    Language English
    Publishing date 2021-04-30
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2021.e01143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hashimoto's encephalopathy: a rare cause of delirium.

    Ogbebor, Osakpolor / Patel, Kavya

    BMJ case reports

    2019  Volume 12, Issue 9

    Abstract: Cognitive impairment is a frequent presentation of patients who come to the hospital. We report a case of a patient who presents with a common symptom, however, with a rare disease. This is an 84-year-old woman with a history of hypertension and atrial ... ...

    Abstract Cognitive impairment is a frequent presentation of patients who come to the hospital. We report a case of a patient who presents with a common symptom, however, with a rare disease. This is an 84-year-old woman with a history of hypertension and atrial fibrillation who was reported to have confusion of 3 weeks. Investigations, including a complete blood count, MRI imaging of the brain, cerebrospinal fluid analysis and paraneoplastic screen, were all negative. Of note, thyroid peroxidase antibody was elevated. She did not have a history of thyroid disease. Following this, an assessment of Hashimoto encephalopathy was made. She was started on steroids and she showed remarkable recovery within 2 months, therefore, confirming the diagnosis. This case report emphasises the need to consider Hashimoto's encephalopathy as a differential for delirium especially when other common aetiologies have been ruled out.
    MeSH term(s) Aged, 80 and over ; Atrial Fibrillation ; Delirium/diagnostic imaging ; Delirium/etiology ; Delirium/immunology ; Delirium/physiopathology ; Diagnosis, Differential ; Encephalitis/complications ; Encephalitis/diagnosis ; Encephalitis/drug therapy ; Encephalitis/physiopathology ; Female ; Hashimoto Disease/complications ; Hashimoto Disease/diagnosis ; Hashimoto Disease/drug therapy ; Hashimoto Disease/physiopathology ; Humans ; Hypertension ; Magnetic Resonance Imaging ; Steroids/therapeutic use ; Travel ; Treatment Outcome
    Chemical Substances Steroids
    Language English
    Publishing date 2019-09-06
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-230118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Neurological Emergencies in the Intensive Care Unit.

    Ogbebor, Osakpolor / Tariq, Shahzaib / Jaber, Tariq / Super, Jamie / Bhanot, Nitin / Rana, Sandeep / Malik, Khalid

    Critical care nursing quarterly

    2022  Volume 46, Issue 1, Page(s) 17–34

    Abstract: Neurological emergencies carry significant morbidity and mortality, and it is necessary to have a multidisciplinary approach involving the emergency physician, the neurologist, the intensivist, and the critical care nursing staff. These disorders can be ... ...

    Abstract Neurological emergencies carry significant morbidity and mortality, and it is necessary to have a multidisciplinary approach involving the emergency physician, the neurologist, the intensivist, and the critical care nursing staff. These disorders can be broadly divided into noninfectious and infectious etiologies. In this article, we review a few of the neurological emergencies that present to the neurological intensive unit, with emphasis on convulsive status epileptics, myasthenia gravis, Guillain-Barré syndrome, meningitis, encephalitis, and brain abscess.
    MeSH term(s) Humans ; Emergencies ; Intensive Care Units ; Critical Care Nursing
    Language English
    Publishing date 2022-11-23
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 639095-x
    ISSN 1550-5111 ; 0887-9303
    ISSN (online) 1550-5111
    ISSN 0887-9303
    DOI 10.1097/CNQ.0000000000000435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: COVID-19: Diagnostic Testing and Challenges.

    Ogbebor, Osakpolor / Min, Zaw / Cheema, Tariq / Bhanot, Nitin

    Critical care nursing quarterly

    2020  Volume 43, Issue 4, Page(s) 343–348

    Abstract: Coronavirus disease-2019 (COVID-19) was declared a pandemic by the World Health Organization on March 11, 2020. Following this, there has been a rapid development in policies and strategies to contain and mitigate the pandemic. One of such strategies ... ...

    Abstract Coronavirus disease-2019 (COVID-19) was declared a pandemic by the World Health Organization on March 11, 2020. Following this, there has been a rapid development in policies and strategies to contain and mitigate the pandemic. One of such strategies involves the development and utilization of testing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative organism of COVID-19. In this article, we explore the diagnostic modalities for COVID-19 based on the available information to date.
    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Reproducibility of Results ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639095-x
    ISSN 1550-5111 ; 0887-9303
    ISSN (online) 1550-5111
    ISSN 0887-9303
    DOI 10.1097/CNQ.0000000000000320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Abdominal Pain, an Atypical Presenting Symptom of Granulomatosis with Polyangiitis.

    Desai, Krishna / Jose, Merin / Ogbebor, Osakpolor

    Cureus

    2020  Volume 12, Issue 4, Page(s) e7864

    Abstract: Granulomatosis with polyangiitis (GPA) formerly known as Wegener's granulomatosis, is an anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV). It is an uncommon disease with an estimated prevalence of 3 in 100,000 individuals with ... ...

    Abstract Granulomatosis with polyangiitis (GPA) formerly known as Wegener's granulomatosis, is an anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV). It is an uncommon disease with an estimated prevalence of 3 in 100,000 individuals with an equal distribution in both sexes. It is characterized by necrotizing granulomatous vasculitis that primarily affects the upper and lower respiratory tracts and the kidneys.  Our patient's initial presentation was abdominal pain with no typical pulmonary or renal manifestations. Along the course of her hospitalization, she had multiple episodes of drop in hemoglobin and a steady increase in serum creatinine which was thought to be due to IV contrast nephropathy. With this case, we project the need for a high index of clinical suspicion to make an early diagnosis, especially in patients with atypical symptoms such as abdominal pain, and acknowledge the fact that IV contrast can possibly act as a second hit in underlying GPA, unmasking the active renal symptoms of the disease.
    Language English
    Publishing date 2020-04-27
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.7864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Toxicological Emergencies.

    Azharuddin, Syed / Ogbebor, Osakpolor / Shuster, Mareena / Smith, Bridget / Arshad, Hammad / Cheema, Tariq

    Critical care nursing quarterly

    2022  Volume 46, Issue 1, Page(s) 82–99

    Abstract: Poisoning, drug overdose, and adverse drug effects continue to be a common encounter, especially in the intensive care unit (ICU). Patients are often critically ill or have a potential to rapidly deteriorate and warrant ICU admission. Adults suffering ... ...

    Abstract Poisoning, drug overdose, and adverse drug effects continue to be a common encounter, especially in the intensive care unit (ICU). Patients are often critically ill or have a potential to rapidly deteriorate and warrant ICU admission. Adults suffering from overdoses rarely give a complete and accurate description of the quantity or type of medications ingested. In most adult cases, multiple substances are involved. A tentative diagnosis in most overdose and poisoning cases can be made by physical examination and simple laboratory tests (electrolyte panel, creatinine, serum osmolarity, urinalysis, etc). Supportive care, with particular attention to airway management, oxygenation, and circulation, is the mainstay of treatment. Basic treatment principles include limiting the amount of toxin absorbed, enhancing the elimination of ingested toxin, and preventing the conversion of non-toxic compounds to toxic metabolites. Drugs or poisons, where specific antidotes or effective therapies exist (especially acetaminophen, salicylates, methanol, ethylene glycol, and digitalis), should be aggressively sought and treated after initial stabilization has been accomplished. For those drugs or poisons where specific quantitative tests are available, levels should be obtained before treatment and may be repeated as clinically indicated.
    MeSH term(s) Adult ; Humans ; Emergencies ; Antidotes/therapeutic use ; Ethylene Glycol ; Methanol ; Poisons
    Chemical Substances Antidotes ; Ethylene Glycol (FC72KVT52F) ; Methanol (Y4S76JWI15) ; Poisons
    Language English
    Publishing date 2022-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639095-x
    ISSN 1550-5111 ; 0887-9303
    ISSN (online) 1550-5111
    ISSN 0887-9303
    DOI 10.1097/CNQ.0000000000000439
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19 ; Diagnostic Testing and Challenges

    Ogbebor, Osakpolor / Min, Zaw / Cheema, Tariq / Bhanot, Nitin

    Critical Care Nursing Quarterly

    2020  Volume 43, Issue 4, Page(s) 343–348

    Keywords Critical Care ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 639095-x
    ISSN 0887-9303
    ISSN 0887-9303
    DOI 10.1097/cnq.0000000000000320
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Disseminated Gonococcal Infection Complicated by Prosthetic Joint Infection: Case Report and Genomic and Phylogenetic Analysis.

    Ogbebor, Osakpolor / Mortimer, Tatum D / Fryling, Kyra / Zhang, Jessica J / Bhanot, Nitin / Grad, Yonatan H

    Open forum infectious diseases

    2020  Volume 8, Issue 2, Page(s) ofaa632

    Abstract: Neisseria ... ...

    Abstract Neisseria gonorrhoeae
    Language English
    Publishing date 2020-12-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofaa632
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  9. Article: Bartonella Endocarditis Presenting as Recurrent Cerebral Mycotic Aneurysm.

    Ogbebor, Osakpolor / Pawate, Veena / Woo, Jean / Kelly, Kevin / Cerejo, Russell / Bhanot, Nitin

    Cureus

    2021  Volume 13, Issue 11, Page(s) e19969

    Abstract: Bartonella henselae is a known cause of culture-negative endocarditis, which can be difficult to diagnose without a high clinical suspicion as specific diagnostic testing is required.  We report the case of a 48-year-old male who presented with altered ... ...

    Abstract Bartonella henselae is a known cause of culture-negative endocarditis, which can be difficult to diagnose without a high clinical suspicion as specific diagnostic testing is required.  We report the case of a 48-year-old male who presented with altered sensorium. A CT of the head showed left-hemispheric intracranial hemorrhage (ICH) likely secondary to ruptured left posterior cerebral artery (PCA) fusiform aneurysm seen on catheter cerebral angiogram, which was treated with endovascular embolization. The patient had a significant history of mitral valve prolapse; however, a transthoracic echocardiogram (TTE) was negative for any vegetation. Blood cultures were also negative. A year later, he presented with another ICH in the PCA territory and was found to have a new left distal PCA aneurysm, which was again treated with endovascular embolization. During that hospitalization, an echocardiogram showed myxomatous changes in the mitral valve with severe mitral regurgitation; however, blood cultures were negative. Further queries about the patient's social history revealed that his spouse had been a cat owner in 2018, which prompted Bartonella henselae testing. The blood work showed elevated immunoglobulin G (IgG) titers for which he was placed on antibiotics. A follow-up catheter angiogram detected a new distal middle cerebral artery (MCA) M4 branch aneurysm treated with surgical clipping. The aneurysm tested positive for Bartonella henselae on polymerase chain reaction (PCR) testing. The patient subsequently underwent successful mitral valve replacement, which also was positive for Bartonella henselae on PCR testing; however, the Warthin-Starry stain was negative. This case demonstrates how a comprehensive history along with persistent evaluation for the underlying etiology of cerebral aneurysms can lead to the diagnosis of Bartonella henselae endocarditis. Cerebral mycotic aneurysms are known complications of endocarditis; however, the underlying infection can be difficult to diagnose. Recognition of this culture-negative endocarditis is critical for the appropriate treatment and management of patients to prevent morbidity and mortality.
    Language English
    Publishing date 2021-11-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.19969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Lemierre's Syndrome: A Case Series.

    Jaber, Tariq M / Saini, Vikram / Ogbebor, Osakpolor / Dumont, Tiffany / Balaan, Marvin / Lega, Mark / Cheema, Tariq

    Cureus

    2021  Volume 13, Issue 10, Page(s) e18436

    Abstract: Lemierre's syndrome (LS) is a potentially fatal complication of oropharyngeal infection, resulting in contiguous suppurative thrombosis of the internal jugular vein (IJV) and septic emboli. It is most commonly associated ... ...

    Abstract Lemierre's syndrome (LS) is a potentially fatal complication of oropharyngeal infection, resulting in contiguous suppurative thrombosis of the internal jugular vein (IJV) and septic emboli. It is most commonly associated with
    Language English
    Publishing date 2021-10-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.18436
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