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  1. Book ; Online ; E-Book: Adaptive phytoremediation practices

    Pandey, Vimal Chandra / Gajic, Gordana / Sharma, Pallavi / Roy, Madhumita

    resilience to climate change

    2022  

    Author's details Vimal Chandra Pandey, Gordana Gajic, Pallavi Sharma, Madhumita Roy
    Keywords Electronic books
    Language English
    Size 1 Online Ressource (353 Seiten)
    Publisher Elsevier
    Publishing place Amsterdam ; Kidlington ; Cambridge, MA
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021270469
    ISBN 978-0-12-823832-5 ; 9780128238318 ; 0-12-823832-1 ; 0128238313
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Addressing lanthanum toxicity in plants: Sources, uptake, accumulation, and mitigation strategies.

    Sharma, Pallavi / Jha, Ambuj Bhushan / Dubey, Rama Shanker

    The Science of the total environment

    2024  Volume 929, Page(s) 172560

    Abstract: Lanthanum (La), the second most abundant rare earth element (REE) is emerging as an environmental issue, with the potential to impact ecosystems and human health. Major sources of soil contamination by La include agricultural, and industrial activities. ... ...

    Abstract Lanthanum (La), the second most abundant rare earth element (REE) is emerging as an environmental issue, with the potential to impact ecosystems and human health. Major sources of soil contamination by La include agricultural, and industrial activities. Lanthanum is non-essential for plant growth but accumulates in various plant parts. The uptake of La by plants is intricately influenced by various factors such as soil pH, redox potential, cation exchange capacity, presence of organic acids and rhizosphere composition. These factors significantly impact the availability and absorption of La ions. Lanthanum impact on plants depends on soil characteristics, cultivated species, developmental stage, La concentration, treatment period, and growth conditions. Excessive La concentrations affect cell division, DNA structure, nutrient uptake, and photosynthesis and induce toxicity symptoms. Plants employ detoxification mechanisms like vacuolar sequestration, osmolyte synthesis, and antioxidant defense system. However, higher concentrations of La can overwhelm these defense mechanisms, leading to adverse effects on plant growth and development. Further, accumulation of La in plants increases the risk for human exposure. Strategies to mitigate La toxicity are, therefore, vital for ecosystem protection. The application of phytoremediation, supplementation, chelation, amendments, and biosorption techniques contributes to the mitigation of La toxicity. This review provides insights into La sources, uptake, toxicity, and alleviation strategies in plants. Identifying research gaps and discussing advancements aims to foster a holistic understanding and develop effective strategies for protecting plant health and ecosystem resilience against La contamination.
    Language English
    Publishing date 2024-04-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.172560
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Enhancing Plasmapheresis Efficacy in Waldenstrom Macroglobulinemia: Overcoming Circuit Clotting Challenges.

    Khan, Urvashi / Sharma, Sourabh / Prasad, Pallavi / Agarwal, Anupam / Jain, Ankur / Jain, Aditi / Verma, Himanshu

    Seminars in dialysis

    2024  Volume 37, Issue 3, Page(s) 282–283

    MeSH term(s) Humans ; Waldenstrom Macroglobulinemia/therapy ; Plasmapheresis/methods ; Treatment Outcome
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article ; Letter
    ZDB-ID 1028193-9
    ISSN 1525-139X ; 0894-0959
    ISSN (online) 1525-139X
    ISSN 0894-0959
    DOI 10.1111/sdi.13206
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Author Reply: Comparison of Norepinephrine and Terlipressin vs Norepinephrine Alone for Management of Septic Shock: A Randomized Control Study.

    Sahoo, Pallavi / Kothari, Nikhil / Sharma, Ankur / Goyal, Shilpa

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2023  Volume 27, Issue 8, Page(s) 603–604

    Abstract: How to cite this article: ...

    Abstract How to cite this article:
    Language English
    Publishing date 2023-07-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Estimation of direct and maternal covariance along with genetic and phenotypic trends of reproduction traits in Murrah buffalo.

    Sharma, Smriti / Dhaka, Surender Singh / Patil, Chandrashekhar Santosh / Rathi, Pallavi

    Reproduction in domestic animals = Zuchthygiene

    2024  Volume 59, Issue 1, Page(s) e14526

    Abstract: The research utilized data from 662 Murrah buffaloes meticulously recorded over 24 years (1996-2019) from historical pedigree sheets maintained at the buffalo farm of the Department of Livestock Production and Management (LPM) at Lala Lajpat Rai ... ...

    Abstract The research utilized data from 662 Murrah buffaloes meticulously recorded over 24 years (1996-2019) from historical pedigree sheets maintained at the buffalo farm of the Department of Livestock Production and Management (LPM) at Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS), Hisar. A series of six univariate animal models were employed to calculate estimates of (co)variance components and heritability for first lactation reproduction traits. Among these models, Model 2 was identified as the best fit for age at first calving (AFC) and calving interval (CI), while Model 1 proved optimal for service period (SP) and conception rate (CR). The heritability estimates for AFC, SP, CR and CI across the models were ranged between 0.11 and 0.32, 0.01 and 0.03, 0.05 and 0.06, and 0.01 and 0.06, respectively. Maternal effects (m
    MeSH term(s) Animals ; Female ; Bison ; Farms ; Fertilization ; Lactation/genetics ; Reproduction/genetics
    Language English
    Publishing date 2024-01-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1015187-4
    ISSN 1439-0531 ; 0936-6768
    ISSN (online) 1439-0531
    ISSN 0936-6768
    DOI 10.1111/rda.14526
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cytochrome

    Saha, Pallavi / Das, Samarpita / Indurthi, Harish K / Kumar, Rohit / Roy, Arnab / Kalia, Nitin Pal / Sharma, Deepak K

    RSC medicinal chemistry

    2024  Volume 15, Issue 3, Page(s) 769–787

    Abstract: ... ...

    Abstract Cytochrome
    Language English
    Publishing date 2024-01-27
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2632-8682
    ISSN (online) 2632-8682
    DOI 10.1039/d3md00587a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nanowonders in agriculture: Unveiling the potential of nanoparticles to boost crop resilience to salinity stress.

    Soni, Sunil / Jha, Ambuj Bhushan / Dubey, Rama Shanker / Sharma, Pallavi

    The Science of the total environment

    2024  Volume 925, Page(s) 171433

    Abstract: Soil salinization significantly affects crop production by reducing crop quality and decreasing yields. Climate change can intensify salinity-related challenges, making the task of achieving global food security more complex. To address the problem of ... ...

    Abstract Soil salinization significantly affects crop production by reducing crop quality and decreasing yields. Climate change can intensify salinity-related challenges, making the task of achieving global food security more complex. To address the problem of elevated salinity stress in crops, nanoparticles (NPs) have emerged as a promising solution. NPs, characterized by their small size and extensive surface area, exhibit remarkable functionality and reactivity. Various types of NPs, including metal and metal oxide NPs, carbon-based NPs, polymer-based NPs, and modified NPs, have displayed potential for mitigating salinity stress in plants. However, the effectiveness of NPs application in alleviating plant stress is dependent upon multiple factors, such as NPs size, exposure duration, plant species, particle composition, and prevailing environmental conditions. Moreover, alterations to NPs surfaces through functionalization and coating also play a role in influencing plant tolerance to salinity stress. NPs can influence cellular processes by impacting signal transduction and gene expression. They counteract reactive oxygen species (ROS), regulate the water balance, enhance photosynthesis and nutrient uptake and promote plant growth and yield. The objective of this review is to discuss the positive impacts of diverse NPs on alleviating salinity stress within plants. The intricate mechanisms through which NPs accomplish this mitigation are also discussed. Furthermore, this review addresses existing research gaps, recent breakthroughs, and prospective avenues for utilizing NPs to combat salinity stress.
    MeSH term(s) Prospective Studies ; Resilience, Psychological ; Agriculture ; Nanoparticles ; Crop Production ; Metal Nanoparticles ; Oxides ; Salinity
    Chemical Substances Oxides
    Language English
    Publishing date 2024-03-06
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.171433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: In Silico Analysis of Natural Plant-Derived Cyclotides with Antifungal Activity against Pathogenic Fungi.

    Sharma, Akshita / Butool, Bisma / Sahu, Pallavi / Mishra, Reema / Mohanty, Aparajita

    Protein and peptide letters

    2024  

    Abstract: Background: Fungal infections in plants, animals, and humans are widespread across the world. Limited classes of antifungal drugs to treat fungal infections and loss of drug efficacy due to rapidly evolving fungal strains pose a challenge in the ... ...

    Abstract Background: Fungal infections in plants, animals, and humans are widespread across the world. Limited classes of antifungal drugs to treat fungal infections and loss of drug efficacy due to rapidly evolving fungal strains pose a challenge in the agriculture and health sectors. Hence, the search for a new class of antifungal agents is imperative. Cyclotides are cyclic plant peptides with multiple bioactivities, including antifungal activity. They have six conserved cysteine residues forming three disulfide linkages (CI-CIV, CII-CV, CIII-CVI) that establish a Cyclic Cystine Knot (CCK) structure, making them extremely resistant to chemical, enzymatic, and thermal attacks.
    Aim: This in silico analysis of natural, plant-derived cyclotides aimed to assess the parameters that can assist and hasten the process of selecting the cyclotides with potent antifungal activity and prioritize them for in vivo/ in vitro experiments.
    Objective: The objective of this study was to conduct in silico studies to compare the physicochemical parameters, sequence diversity, surface structures, and membrane-cyclotide interactions of experimentally screened (from literature survey) potent (MIC ≤ 20 μM) and non-potent (MIC > 20 μM) cyclotides for antifungal activity.
    Methodology: Cyclotide sequences assessed for antifungal activity were retrieved from the database (Cybase). Various online and offline tools were used for sequence-based studies, such as physicochemical parameters, sequence diversity, and neighbor-joining trees. Structure-based studies involving surface structure analysis and membrane-cyclotide interaction were also carried out. All investigations were conducted in silico.
    Result: Physicochemical parameter values, viz. isoelectric point, net charge, and the number of basic amino acids, were significantly higher in potent cyclotides compared to non-potent cyclotides. The surface structure of potent cyclotides showed a larger hydrophobic patch with a higher number of hydrophobic amino acids. Furthermore, the membrane-cyclotide interaction studies of potent cyclotides revealed lower transfer free energy (ΔG transfer) and higher penetration depth into fungal membranes, indicating higher binding stability and membrane-disruption ability.
    Conclusion: These in silico studies can be applied for rapidly identifying putatively potent antifungal cyclotides for in vivo and in vitro experiments, which will ultimately be relevant in the agriculture and pharmaceutical sectors.
    Language English
    Publishing date 2024-03-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1280776-x
    ISSN 1875-5305 ; 0929-8665
    ISSN (online) 1875-5305
    ISSN 0929-8665
    DOI 10.2174/0109298665295545240223114346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dietary flavonoids-rich

    Sharma, Pallavi / Dhiman, Poonam / Singh, Damanpreet

    Nutritional neuroscience

    2022  Volume 26, Issue 7, Page(s) 582–593

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Mice ; Animals ; Seizures/chemically induced ; Kindling, Neurologic ; Pentylenetetrazole/pharmacology ; Citrus ; Flavonoids/therapeutic use ; Flavonoids/pharmacology ; Anticonvulsants/pharmacology
    Chemical Substances Pentylenetetrazole (WM5Z385K7T) ; Flavonoids ; Anticonvulsants
    Language English
    Publishing date 2022-05-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1447449-9
    ISSN 1476-8305 ; 1028-415X
    ISSN (online) 1476-8305
    ISSN 1028-415X
    DOI 10.1080/1028415X.2022.2071807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Concomitant Non-V600E BRAF and KRAS Mutations in Colorectal Carcinoma by Next-Generation Sequencing: A Distinct Subtype.

    Srivastava, Pallavi / Mishra, Sridhar / Shukla, Saumya / Sharma, Pooja / Husain, Nuzhat

    International journal of surgical pathology

    2023  , Page(s) 10668969231215425

    Abstract: The RAS-RAF-MEK-ERK signaling cascade is the most frequently affected signaling pathway in colorectal cancer. ...

    Abstract The RAS-RAF-MEK-ERK signaling cascade is the most frequently affected signaling pathway in colorectal cancer.
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1336393-1
    ISSN 1940-2465 ; 1066-8969
    ISSN (online) 1940-2465
    ISSN 1066-8969
    DOI 10.1177/10668969231215425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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