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  1. Book: Global progress on use of vaccines for invasive Salmonella infections

    Crump, John A.

    (Vaccine ; 33, Suppl. 3)

    2015  

    Author's details guest ed.: John A. Crump
    Series title Vaccine ; 33, Suppl. 3
    Collection
    Language English
    Size C67 S. : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT018713731
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1930 -33,Suppl.3- not available for loan Zeitschriften-Lesesaal

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  2. Book: Invasive Salmonella disease in Africa

    Crump, John A.

    (Clinical infectious diseases ; volume 61, supplement 4 (1 November 2015))

    2015  

    Author's details guest editors: John A. Crump, MB ChB, MD, DTM&H, FRACP, FRCPA, FRCP; Robert S. Heyderman, PhD, FRCP, DTM&H
    Series title Clinical infectious diseases ; volume 61, supplement 4 (1 November 2015)
    Collection
    Language English
    Size Seite S235-S385, Illustrationen
    Publisher Oxford University Press
    Publishing place Cary, NC
    Publishing country United States
    Document type Book
    HBZ-ID HT018854742
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 1505 -61,Suppl.4- not available for loan Zeitschriften-Lesesaal

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  3. Article: Lived Experiences of Cognitive Dysfunction in Fibromyalgia: How Patients Discuss Their Experiences and Suggestions for Patient Education.

    Millar, Kayla A / Crump, Lyndsay / LaChapelle, Diane L

    Journal of patient experience

    2024  Volume 11, Page(s) 23743735241229385

    Abstract: Cognitive dysfunction (CD) is a common, impairing symptom experienced by persons with fibromyalgia (FM). This study explored how individuals with FM describe their experience of CD in an online peer support environment. Posts referencing cognitive ... ...

    Abstract Cognitive dysfunction (CD) is a common, impairing symptom experienced by persons with fibromyalgia (FM). This study explored how individuals with FM describe their experience of CD in an online peer support environment. Posts referencing cognitive symptoms were extracted from two Facebook FM peer support groups at two timepoints. Using inductive Thematic Analysis, key discussion themes were identified and compared across groups and time. Four themes represented the way members described their cognitive experiences in FM: understanding and describing CD experiences, distrust of cognitive abilities, choosing between pain and medication side effects, and misunderstanding and judgement from others. Two themes represented the impact of CD on members' lives: impaired social interaction and loss of identity. Group members described broad impairments in daily functioning that significantly and negatively impacted their quality of life, indicating CD symptoms may play a more prominent role in the FM experience than previously understood. An infographic is included to aid patient education and help facilitate patient-provider discussions of CD symptoms.
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2857285-3
    ISSN 2374-3743 ; 2374-3735
    ISSN (online) 2374-3743
    ISSN 2374-3735
    DOI 10.1177/23743735241229385
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Endometriosis: A review of recent evidence and guidelines.

    Crump, Jessica / Suker, Adriana / White, Louise

    Australian journal of general practice

    2024  Volume 53, Issue 1-2, Page(s) 11–18

    Abstract: Background: Endometriosis is a chronic inflammatory condition defined as endometrial-like tissue proliferating outside the uterus. It is a common yet frequently under-recognised condition affecting one in nine Australian women.: Objective: This paper ...

    Abstract Background: Endometriosis is a chronic inflammatory condition defined as endometrial-like tissue proliferating outside the uterus. It is a common yet frequently under-recognised condition affecting one in nine Australian women.
    Objective: This paper aims to provide a summary of the recommendations for the diagnosis and management of endometriosis-associated pain and infertility from the most recent evidence-based guidelines on endometriosis by the European Society of Human Reproduction and Embryology, the Royal Australian College of Obstetricians and Gynaecologists and the National Institute for Health and Care Excellence.
    Discussion: Effective management of endometriosis requires prompt diagnosis to enable early multidisciplinary intervention that aligns with patient needs and priorities. Assessment includes a thorough history, pelvic examination where appropriate and referral for transvaginal ultrasound and/or magnetic resonance imaging. If endometriosis is suspected based on clinical symptoms but imaging is negative or empirical treatment is ineffective, individuals should be referred to a gynaecologist for further assessment and consideration of laparoscopy. Management options include hormonal and surgical therapies.
    MeSH term(s) Female ; Humans ; Endometriosis/complications ; Endometriosis/diagnosis ; Endometriosis/therapy ; Pelvic Pain/diagnosis ; Pelvic Pain/drug therapy ; Australia ; Ultrasonography ; Magnetic Resonance Imaging
    Language English
    Publishing date 2024-02-05
    Publishing country Australia
    Document type Review ; Journal Article
    ZDB-ID 2924889-9
    ISSN 2208-7958 ; 2208-794X
    ISSN (online) 2208-7958
    ISSN 2208-794X
    DOI 10.31128/AJGP/04-23-6805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2235: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Towards equitable scheduling of global health teleconferences: a spatial exploration of the world's population and health by time zone.

    Crump, John A / Davies, Tilman M

    BMJ open

    2022  Volume 12, Issue 5, Page(s) e056696

    Abstract: Objectives: To examine the world's population, development, and health by condensed Coordinated Universal Time (UTC) offset to support a normative position on how to most defensibly schedule global health teleconferences with the primary goal of ... ...

    Abstract Objectives: To examine the world's population, development, and health by condensed Coordinated Universal Time (UTC) offset to support a normative position on how to most defensibly schedule global health teleconferences with the primary goal of advancing equitable regard for participants by health condition.
    Design: Spatial exploration examined through the lens of equitable regard for participants.
    Setting: The Earth.
    Participants: The global population.
    Main outcome measures: Global population, countries, Human Development Index (HDI), and health measured in total and disease-specific disability-adjusted life years (DALYs) per 100 000 per year by UTC offset. Strengths and weaknesses of scheduling teleconferences accordingly to alternative approaches.
    Results: The UTC offset with the largest population of approximately 1 724 million persons occurred in UTC+5, largest country count of approximately 40 countries in UTC+1, and the lowest median HDI of 0.527 occurred in UTC0. The highest median total DALYs per 100 000 per year of 41 873 occurred in UTC+11, highest median HIV/AIDS DALYs per 100 000 per year of 941 in UTC0, and highest median typhoid and paratyphoid fevers DALYs per 100 000 per year of 279 occurred in UTC+5. Hypothetical teleconference scheduling scenarios generated temporal distances of up to 11 hours to UTC offsets representing the most countries and greatest number of DALYs per 100 000 per year. Teleconference scheduling based on egoism was considered to be problematic, and contractualism as unrealistically demanding. Utilitarianism resulted in the risk of systematically disadvantaging small, temporally remote groups. Egalitarianism offered equality, but prioritarianism offered the possibility of addressing health inequities.
    Conclusions: Global health teleconferences may generate great temporal distances between participants compromising representative participation, as well as the well-being of attendees. Our spatial exploration of the world's population and health by UTC offset may be used to support a normative position on scheduling global health teleconferences that enhance progress towards health equity.
    MeSH term(s) Global Health ; Health Equity ; Humans ; Quality-Adjusted Life Years ; Telecommunications ; Typhoid Fever
    Language English
    Publishing date 2022-05-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2021-056696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Beyond αβ T cells: NK, iNKT, and γδT cell biology in leukemic patients and potential for off-the-shelf adoptive cell therapies for AML.

    Kent, Andrew / Crump, Lyndsey S / Davila, Eduardo

    Frontiers in immunology

    2023  Volume 14, Page(s) 1202950

    Abstract: Acute myeloid leukemia (AML) remains an elusive disease to treat, let alone cure, even after highly intensive therapies such as stem cell transplants. Adoptive cell therapeutic strategies based on conventional alpha beta (αβ)T cells are an active area of ...

    Abstract Acute myeloid leukemia (AML) remains an elusive disease to treat, let alone cure, even after highly intensive therapies such as stem cell transplants. Adoptive cell therapeutic strategies based on conventional alpha beta (αβ)T cells are an active area of research in myeloid neoplasms given their remarkable success in other hematologic malignancies, particularly B-cell-derived acute lymphoid leukemia, myeloma, and lymphomas. Several limitations have hindered clinical application of adoptive cell therapies in AML including lack of leukemia-specific antigens, on-target-off-leukemic toxicity, immunosuppressive microenvironments, and leukemic stem cell populations elusive to immune recognition and destruction. While there are promising T cell-based therapies including chimeric antigen receptor (CAR)-T designs under development, other cytotoxic lymphocyte cell subsets have unique phenotypes and capabilities that might be of additional benefit in AML treatment. Of particular interest are the natural killer (NK) and unconventional T cells known as invariant natural killer T (iNKT) and gamma delta (γδ) T cells. NK, iNKT, and γδT cells exhibit intrinsic anti-malignant properties, potential for alloreactivity, and human leukocyte-antigen (HLA)-independent function. Here we review the biology of each of these unconventional cytotoxic lymphocyte cell types and compare and contrast their strengths and limitations as the basis for adoptive cell therapies for AML.
    MeSH term(s) Humans ; T-Lymphocytes ; Leukemia, Myeloid, Acute/therapy ; Cell- and Tissue-Based Therapy ; Gamma Rays ; Hematologic Neoplasms ; Tumor Microenvironment
    Language English
    Publishing date 2023-08-15
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1202950
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Costs associated with treating uveal melanoma are understudied.

    Crump, R Trafford / Khan, Asher / Weis, Ezekiel

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

    2023  Volume 58, Issue 6, Page(s) e240–e241

    MeSH term(s) Humans ; Melanoma/diagnosis ; Melanoma/therapy ; Uveal Neoplasms/diagnosis ; Uveal Neoplasms/therapy
    Language English
    Publishing date 2023-07-21
    Publishing country England
    Document type Letter
    ZDB-ID 80091-0
    ISSN 1715-3360 ; 0008-4182
    ISSN (online) 1715-3360
    ISSN 0008-4182
    DOI 10.1016/j.jcjo.2023.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 588: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Ivermectin: enigmatic multifaceted 'wonder' drug continues to surprise and exceed expectations.

    Crump, Andy

    The Journal of antibiotics

    2017  Volume 70, Issue 5, Page(s) 495–505

    Abstract: Over the past decade, the global scientific community have begun to recognize the unmatched value of an extraordinary drug, ivermectin, that originates from a single microbe unearthed from soil in Japan. Work on ivermectin has seen its discoverer, ... ...

    Abstract Over the past decade, the global scientific community have begun to recognize the unmatched value of an extraordinary drug, ivermectin, that originates from a single microbe unearthed from soil in Japan. Work on ivermectin has seen its discoverer, Satoshi Ōmura, of Tokyo's prestigious Kitasato Institute, receive the 2014 Gairdner Global Health Award and the 2015 Nobel Prize in Physiology or Medicine, which he shared with a collaborating partner in the discovery and development of the drug, William Campbell of Merck & Co. Incorporated. Today, ivermectin is continuing to surprise and excite scientists, offering more and more promise to help improve global public health by treating a diverse range of diseases, with its unexpected potential as an antibacterial, antiviral and anti-cancer agent being particularly extraordinary.
    MeSH term(s) Animals ; Antiparasitic Agents/history ; Antiparasitic Agents/pharmacology ; Drug Design ; Drug Discovery ; Global Health ; History, 20th Century ; History, 21st Century ; Humans ; Ivermectin/history ; Ivermectin/isolation & purification ; Ivermectin/pharmacology ; Japan ; Nobel Prize ; Public Health
    Chemical Substances Antiparasitic Agents ; Ivermectin (70288-86-7)
    Language English
    Publishing date 2017-05
    Publishing country Japan
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 390800-8
    ISSN 1881-1469 ; 0021-8820 ; 0368-3532
    ISSN (online) 1881-1469
    ISSN 0021-8820 ; 0368-3532
    DOI 10.1038/ja.2017.11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Progress in Typhoid Fever Epidemiology.

    Crump, John A

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2018  Volume 68, Issue Suppl 1, Page(s) S4–S9

    Abstract: Salmonella enterica subspecies enterica serovar Typhi (Salmonella Typhi) is the cause of typhoid fever and a human host-restricted organism. Our understanding of the global burden of typhoid fever has improved in recent decades, with both an increase in ... ...

    Abstract Salmonella enterica subspecies enterica serovar Typhi (Salmonella Typhi) is the cause of typhoid fever and a human host-restricted organism. Our understanding of the global burden of typhoid fever has improved in recent decades, with both an increase in the number and geographic representation of high-quality typhoid fever incidence studies, and greater sophistication of modeling approaches. The 2017 World Health Organization Strategic Advisory Group of Experts on Immunization recommendation for the introduction of typhoid conjugate vaccines for infants and children aged >6 months in typhoid-endemic countries is likely to require further improvements in our understanding of typhoid burden at the global and national levels. Furthermore, the recognition of the critical and synergistic role of water and sanitation improvements in concert with vaccine introduction emphasize the importance of improving our understanding of the sources, patterns, and modes of transmission of Salmonella Typhi in diverse settings.
    MeSH term(s) Child, Preschool ; Disease Reservoirs ; Global Health ; Humans ; Incidence ; Infant ; Practice Guidelines as Topic ; Typhoid Fever/epidemiology ; Typhoid Fever/prevention & control ; Typhoid Fever/transmission ; Typhoid-Paratyphoid Vaccines/immunology
    Chemical Substances Typhoid-Paratyphoid Vaccines
    Language English
    Publishing date 2018-12-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciy846
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 480: Show issues

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  10. Article ; Online: Separating conscious and unconscious perception in animals.

    Crump, Andrew / Birch, Jonathan

    Learning & behavior

    2021  Volume 49, Issue 4, Page(s) 347–348

    Abstract: In a new study, Ben-Haim et al. use subliminal stimuli to separate conscious and unconscious perception in macaques. A programme of this type, using a range of cognitive tasks, is a promising way to look for conscious perception in more controversial ... ...

    Abstract In a new study, Ben-Haim et al. use subliminal stimuli to separate conscious and unconscious perception in macaques. A programme of this type, using a range of cognitive tasks, is a promising way to look for conscious perception in more controversial cases.
    MeSH term(s) Animals ; Consciousness ; Subliminal Stimulation ; Visual Perception
    Language English
    Publishing date 2021-11-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2048665-0
    ISSN 1543-4508 ; 1543-4494
    ISSN (online) 1543-4508
    ISSN 1543-4494
    DOI 10.3758/s13420-021-00479-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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