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  1. Article ; Online: Heteroresistance in tuberculosis: are we missing drug-resistant bacteria hiding in plain sight?

    Park, Mirae / Satta, Giovanni / Haldar, Pranabashis

    Thorax

    2024  

    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Editorial
    ZDB-ID 204353-1
    ISSN 1468-3296 ; 0040-6376
    ISSN (online) 1468-3296
    ISSN 0040-6376
    DOI 10.1136/thorax-2024-221409
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    In stock of ZB MED Cologne/Königswinter

    Ui III Zs.83: Show issues Location:
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  2. Article ; Online: Thermomonas paludicola

    Kim, Mirae / Park, Miri S / Kang, Ilnam / Cho, Jang-Cheon

    International journal of systematic and evolutionary microbiology

    2023  Volume 73, Issue 2

    Abstract: A Gram-stain-negative, aerobic, rod-shaped and motile bacterium, designated ... ...

    Abstract A Gram-stain-negative, aerobic, rod-shaped and motile bacterium, designated IMCC34681
    MeSH term(s) Fatty Acids/chemistry ; Phospholipids/chemistry ; Lotus ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Sodium Chloride ; Wetlands ; Sequence Analysis, DNA ; DNA, Bacterial/genetics ; Base Composition ; Bacterial Typing Techniques ; Republic of Korea
    Chemical Substances Fatty Acids ; Phospholipids ; RNA, Ribosomal, 16S ; Sodium Chloride (451W47IQ8X) ; DNA, Bacterial
    Language English
    Publishing date 2023-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2002336-4
    ISSN 1466-5034 ; 1466-5026
    ISSN (online) 1466-5034
    ISSN 1466-5026
    DOI 10.1099/ijsem.0.005737
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 409: Show issues Location:
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  3. Article ; Online: Economic analysis of the circular economy based on waste plastic pyrolysis oil: a case of the university campus.

    Park, Hayoung / Kim, Kayoung / Yu, Mirae / Yun, Zhihao / Lee, Sanghun

    Environment, development and sustainability

    2023  , Page(s) 1–21

    Abstract: Recently, the concept of a circular economy for carbon neutrality is emerging. In particular, waste plastics are one of the key wastes, and efforts are being made to recycle them as energy rather than dispose of them. Accordingly, the technology of ... ...

    Abstract Recently, the concept of a circular economy for carbon neutrality is emerging. In particular, waste plastics are one of the key wastes, and efforts are being made to recycle them as energy rather than dispose of them. Accordingly, the technology of producing and utilizing pyrolysis oil from waste plastics attracts attention. As it is an early stage of technology development, however, there are not many demonstrations and papers that analyze the technology broadly. The goal of this study is to propose building a circular economy on a university campus through waste plastic pyrolysis oil technology. To show its feasibility, waste plastic pyrolysis oil technology is analyzed comprehensively from economic, environmental, and policy perspectives using the scenario analysis technique on the university campus level. A methodology of the scenario analysis technique enables predicting the uncertainties. Since plastic pyrolysis oil technologies and carbon neutrality are accompanied by many uncertainties, this technique is expected to be an appropriate methodology for this study. First, the amount of pyrolysis oil production from waste plastics from the campus is estimated. Then, the cost and carbon emissions from waste plastics are estimated if the pyrolysis oil technology is used instead of the traditional waste disposal process. As a result, the total economic profits of up to 425,484,022 won/year (354,570.01 $/year) are expected when a circular economy is built using waste plastic pyrolysis oil. In addition, it is also confirmed that greenhouse gas (GHG) emissions can be reduced by up to 840,891 kgCO
    Language English
    Publishing date 2023-03-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2015291-7
    ISSN 1573-2975 ; 1387-585X
    ISSN (online) 1573-2975
    ISSN 1387-585X
    DOI 10.1007/s10668-023-02963-1
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  4. Article ; Online: Use of Xpert MTB/RIF and Xpert Ultra in extrapulmonary tuberculosis.

    Park, Mirae / Kon, Onn Min

    Expert review of anti-infective therapy

    2020  Volume 19, Issue 1, Page(s) 65–77

    Abstract: Introduction: Tuberculosis (TB) remains a major global health burden. There still remains a large gap between the notified and estimated incident cases. Extrapulmonary (EP) TB represents 15% of all TB cases and the diagnosis is more challenging due to ... ...

    Abstract Introduction: Tuberculosis (TB) remains a major global health burden. There still remains a large gap between the notified and estimated incident cases. Extrapulmonary (EP) TB represents 15% of all TB cases and the diagnosis is more challenging due to the paucity of the organism. Smear microscopy is often insensitive and culture methods are prolonged. With the introduction of Xpert MTB/RIF and more recently Xpert Ultra, this has changed TB diagnostics by providing a rapid accessible platform to diagnose TB and identify rifampicin resistance within 2 h.
    Areas covered: The diagnostic accuracy and the clinical role of Xpert MTB/RIF and Xpert Ultra in the different forms of EPTB.
    Expert opinion: Whilst significant advances have been made in TB diagnostics, there is still a need to optimize the diagnostic yield of Xpert MTB/RIF and Xpert Ultra in EPTB samples. Research is needed to facilitate standardization and optimal preparation of samples as well as understanding the role of Xpert MTB/RIF and Xpert Ultra in different burden settings. Alongside the current GeneXpert platform, the launch of rapid second-line drug resistance polymerase chain reactions and whole genome sequencing may help tackle the global health burden with a more comprehensive diagnostic approach and appropriate treatment.
    MeSH term(s) Antitubercular Agents/pharmacology ; Drug Resistance, Bacterial ; Humans ; Polymerase Chain Reaction/methods ; Rifampin/pharmacology ; Time Factors ; Tuberculosis/diagnosis ; Tuberculosis/drug therapy ; Tuberculosis/microbiology
    Chemical Substances Antitubercular Agents ; Rifampin (VJT6J7R4TR)
    Language English
    Publishing date 2020-09-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2020.1810565
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  5. Article ; Online: Improving Text-to-SQL with a Hybrid Decoding Method

    Geunyeong Jeong / Mirae Han / Seulgi Kim / Yejin Lee / Joosang Lee / Seongsik Park / Harksoo Kim

    Entropy, Vol 25, Iss 513, p

    2023  Volume 513

    Abstract: Text-to-SQL is a task that converts natural language questions into SQL queries. Recent text-to-SQL models employ two decoding methods: sketch-based and generation-based, but each has its own shortcomings. The sketch-based method has limitations in ... ...

    Abstract Text-to-SQL is a task that converts natural language questions into SQL queries. Recent text-to-SQL models employ two decoding methods: sketch-based and generation-based, but each has its own shortcomings. The sketch-based method has limitations in performance as it does not reflect the relevance between SQL elements, while the generation-based method may increase inference time and cause syntactic errors. Therefore, we propose a novel decoding method, Hybrid decoder, which combines both methods. This reflects inter-SQL element information and defines elements that can be generated, enabling the generation of syntactically accurate SQL queries. Additionally, we introduce a Value prediction module for predicting values in the WHERE clause. It simplifies the decoding process and reduces the size of vocabulary by predicting values at once, regardless of the number of conditions. The results of evaluating the significance of Hybrid decoder indicate that it improves performance by effectively incorporating mutual information among SQL elements, compared to the sketch-based method. It also efficiently generates SQL queries by simplifying the decoding process in the generation-based method. In addition, we design a new evaluation measure to evaluate if it generates syntactically correct SQL queries. The result demonstrates that the proposed model generates syntactically accurate SQL queries.
    Keywords semantic parsing ; text-to-SQL ; pointer network ; natural language processing ; Science ; Q ; Astrophysics ; QB460-466 ; Physics ; QC1-999
    Subject code 005
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Giant Duckweed (

    Lee, Hojun / De Saeger, Jonas / Bae, Sunwoo / Kim, Mirae / Depuydt, Stephen / Heynderickx, Philippe M / Wu, Di / Han, Taejun / Park, Jihae

    Toxics

    2023  Volume 11, Issue 9

    Abstract: Aquatic environment are often contaminated with heavy metals from various industrial sources. However, physicochemical techniques for pollutant detection are limited, thus prompting the need for additional bioassays. We investigated the use of greater ... ...

    Abstract Aquatic environment are often contaminated with heavy metals from various industrial sources. However, physicochemical techniques for pollutant detection are limited, thus prompting the need for additional bioassays. We investigated the use of greater duckweed (
    Language English
    Publishing date 2023-09-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2733883-6
    ISSN 2305-6304 ; 2305-6304
    ISSN (online) 2305-6304
    ISSN 2305-6304
    DOI 10.3390/toxics11090788
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  7. Article ; Online: Acute mitral valve dysfunction and cardiogenic shock due to escape of prosthetic mechanical leaflet

    Mirae Lee / Su A Jo / Ik Hyun Park

    The Korean Journal of Internal Medicine, Vol 35, Iss 1, Pp 250-

    2020  Volume 251

    Keywords Medicine ; R
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher The Korean Association of Internal Medicine
    Document type Article ; Online
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  8. Article ; Online: Improving Text-to-SQL with a Hybrid Decoding Method.

    Jeong, Geunyeong / Han, Mirae / Kim, Seulgi / Lee, Yejin / Lee, Joosang / Park, Seongsik / Kim, Harksoo

    Entropy (Basel, Switzerland)

    2023  Volume 25, Issue 3

    Abstract: Text-to-SQL is a task that converts natural language questions into SQL queries. Recent text-to-SQL models employ two decoding methods: sketch-based and generation-based, but each has its own shortcomings. The sketch-based method has limitations in ... ...

    Abstract Text-to-SQL is a task that converts natural language questions into SQL queries. Recent text-to-SQL models employ two decoding methods: sketch-based and generation-based, but each has its own shortcomings. The sketch-based method has limitations in performance as it does not reflect the relevance between SQL elements, while the generation-based method may increase inference time and cause syntactic errors. Therefore, we propose a novel decoding method, Hybrid decoder, which combines both methods. This reflects inter-SQL element information and defines elements that can be generated, enabling the generation of syntactically accurate SQL queries. Additionally, we introduce a Value prediction module for predicting values in the WHERE clause. It simplifies the decoding process and reduces the size of vocabulary by predicting values at once, regardless of the number of conditions. The results of evaluating the significance of Hybrid decoder indicate that it improves performance by effectively incorporating mutual information among SQL elements, compared to the sketch-based method. It also efficiently generates SQL queries by simplifying the decoding process in the generation-based method. In addition, we design a new evaluation measure to evaluate if it generates syntactically correct SQL queries. The result demonstrates that the proposed model generates syntactically accurate SQL queries.
    Language English
    Publishing date 2023-03-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e25030513
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  9. Article ; Online: Antiobesity and antidiabetic effects of the dairy bacterium Propionibacterium freudenreichii MJ2 in high-fat diet-induced obese mice by modulating lipid metabolism

    Mirae An / Yeon-Hee Park / Young-Hee Lim

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 14

    Abstract: Abstract Obesity can cause chronic metabolic disorders such as type 2 diabetes, hyperlipidemia, and nonalcoholic fatty liver diseases. The aim of this study was to investigate the antiobesity and antidiabetic effects of the dairy bacterium P. ... ...

    Abstract Abstract Obesity can cause chronic metabolic disorders such as type 2 diabetes, hyperlipidemia, and nonalcoholic fatty liver diseases. The aim of this study was to investigate the antiobesity and antidiabetic effects of the dairy bacterium P. freudenreichii MJ2 isolated from raw milk using 3T3-L1 cells and high-fat diet (HFD)-induced obese mice. Lipid accumulation and the expression levels of genes related to lipid metabolism, such as preadipocytic gene (Pref-1), adipogenic genes (PPARγ and C/EBPα), and lipogenic genes (FAS, SCD-1, and ACC), significantly decreased in heat-killed P. freudenreichii MJ2 (hkMJ2)-treated adipocytes. Live P. freudenreichii MJ2 (MJ2), hkMJ2, and Lactobacillus plantarum (LP) decreased body weight gain in HFD-induced obese mice compared with the model group. The liver and epididymal white adipose tissue weights in the MJ2-, hkMJ2- and LP-treated groups were significantly lower than those in the model group. The expression levels of genes and proteins related to adipogenesis and lipogenesis significantly decreased and lipolysis (HSL and ATGL) increased in the MJ2-, hkMJ2-, and LP-treated groups. The expression levels of genes related to fatty acid β-oxidation (CPT-1α and ACOX1) increased in the MJ2-, hkMJ2-, and LP-treated groups. In addition, blood glucose and fasting insulin levels in the MJ2- and hkMJ2-treated groups decreased compared with those in the model group. P. freudenreichii MJ2 ameliorate insulin resistance by obesity. In conclusion, both MJ2 and hkMJ2 alleviate obesity and metabolic syndrome.
    Keywords Medicine ; R ; Science ; Q
    Subject code 616
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
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  10. Article ; Online: Background free

    Yang, Seung-Hyun / Kim, Jiwon / Lee, Tae Geol / Park, Mirae / Son, Hye Young / Joo, Chan Gyu / Shim, Jeong Hyun / Lee, Youngbok / Huh, Yong-Min

    The Analyst

    2023  Volume 148, Issue 21, Page(s) 5355–5360

    Abstract: This study demonstrated the potential of 50 nm PEGylated Si NPs for high- ... ...

    Abstract This study demonstrated the potential of 50 nm PEGylated Si NPs for high-resolution
    Language English
    Publishing date 2023-10-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an01395b
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