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  1. Article: Editorial: Foods, dietary supplements, and herbal products treating the diseases of the 21st century: moving from traditional to scientific research.

    Sanches Silva, Ana / Garg, Neha / Nile, Shivraj Hariram

    Frontiers in nutrition

    2024  Volume 11, Page(s) 1388181

    Language English
    Publishing date 2024-03-18
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2024.1388181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Modulation of Expression Levels of Various Cytokines and Inflammatory Responses by Glucosinolate Derivatives.

    Baskar, Venkidasamy / Krishnan, Murugesan / Rajakumar, Govindasamy / Hariram Nile, Shivraj / Thiruvengadam, Muthu

    Current topics in medicinal chemistry

    2023  Volume 23, Issue 17, Page(s) 1575–1578

    MeSH term(s) Glucosinolates/pharmacology ; Glucosinolates/metabolism ; Cytokines
    Chemical Substances Glucosinolates ; Cytokines
    Language English
    Publishing date 2023-06-27
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2064823-6
    ISSN 1873-4294 ; 1568-0266
    ISSN (online) 1873-4294
    ISSN 1568-0266
    DOI 10.2174/1568026623666230605120626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Trypsin from Pyloric Caeca of Asian Seabass: Purification, Characterization, and Its Use in the Hydrolysis of Acid-Soluble Collagen.

    Patil, Umesh / Baloch, Khurshid Ahmed / Nile, Shivraj Hariram / Kim, Jun Tae / Benjakul, Soottawat

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 15

    Abstract: The study aimed to purify trypsin from the pyloric caeca of Asian seabass ( ...

    Abstract The study aimed to purify trypsin from the pyloric caeca of Asian seabass (
    Language English
    Publishing date 2023-08-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12152937
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19

    Nile, Shivraj Hariram / Kai, Guoyin

    Indian journal of microbiology. 2021 Mar., v. 61, no. 1

    2021  

    Abstract: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing potentially fatal coronavirus disease-19 (COVID-19), with a significant health and economic burden around the globe. Currently many clinical studies are undergoing but still ... ...

    Abstract The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing potentially fatal coronavirus disease-19 (COVID-19), with a significant health and economic burden around the globe. Currently many clinical studies are undergoing but still there is no any specific approved therapy or drug established for effective treatment of COVID-19. This review aimed to analyses various clinical studies which have been registered in www.clinicaltrials.gov and http://www.chictr.org.cn were registered with natural plant-based medicines and Traditional Chinese medicine (TCM) for discovering effective treatment and prevention of COVID-19. Total 46 and 64 natural drug and TCM interventions were identified which mainly determined the preventive strategies and possible treatments for COVID-19 infection. We identified that most of the clinical trial undergoing on natural compound like heparin and vitamin C as therapeutic agents and immune boosters for against COVID-19. Traditional Chinese medicines and herbal medicines can be effectively used as a preventive therapy against COVID-19 and after successful clinical trials and these potential therapies can be promoted by countries around the world.
    Keywords COVID-19 infection ; Oriental traditional medicine ; Severe acute respiratory syndrome coronavirus 2 ; ascorbic acid ; clinical trials ; heparin ; microbiology ; therapeutics
    Language English
    Dates of publication 2021-03
    Size p. 10-15.
    Publishing place Springer India
    Document type Article
    Note NAL-AP-2-clean ; Review
    ZDB-ID 413422-9
    ISSN 0973-7715 ; 0046-8991
    ISSN (online) 0973-7715
    ISSN 0046-8991
    DOI 10.1007/s12088-020-00919-x
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19.

    Nile, Shivraj Hariram / Kai, Guoyin

    Indian journal of microbiology

    2020  Volume 61, Issue 1, Page(s) 10–15

    Abstract: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing potentially fatal coronavirus disease-19 (COVID-19), with a significant health and economic burden around the globe. Currently many clinical studies are undergoing but still ... ...

    Abstract The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing potentially fatal coronavirus disease-19 (COVID-19), with a significant health and economic burden around the globe. Currently many clinical studies are undergoing but still there is no any specific approved therapy or drug established for effective treatment of COVID-19. This review aimed to analyses various clinical studies which have been registered in www.clinicaltrials.gov and http://www.chictr.org.cn were registered with natural plant-based medicines and Traditional Chinese medicine (TCM) for discovering effective treatment and prevention of COVID-19. Total 46 and 64 natural drug and TCM interventions were identified which mainly determined the preventive strategies and possible treatments for COVID-19 infection. We identified that most of the clinical trial undergoing on natural compound like heparin and vitamin C as therapeutic agents and immune boosters for against COVID-19. Traditional Chinese medicines and herbal medicines can be effectively used as a preventive therapy against COVID-19 and after successful clinical trials and these potential therapies can be promoted by countries around the world.
    Supplementary information: The online version contains supplementary material available at (10.1007/s12088-020-00919-x).
    Language English
    Publishing date 2020-12-30
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 413422-9
    ISSN 0973-7715 ; 0046-8991
    ISSN (online) 0973-7715
    ISSN 0046-8991
    DOI 10.1007/s12088-020-00919-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Corrigendum to <Systematic exploration of Astragalus membranaceus and Panax ginseng as immune regulators: Insights from the comparative biological and computational analysis>.

    Junqiu, Liu / Hariram, Nile Shivraj / Guoliang, Xu / Yuesheng, Wang / Guoyin, Kai

    Phytomedicine : international journal of phytotherapy and phytopharmacology

    2021  Volume 91, Page(s) 153618

    Language English
    Publishing date 2021-06-20
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1205240-1
    ISSN 1618-095X ; 0944-7113
    ISSN (online) 1618-095X
    ISSN 0944-7113
    DOI 10.1016/j.phymed.2021.153618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Antifungal Properties of Biogenic Selenium Nanoparticles Functionalized with Nystatin for the Inhibition of

    Nile, Shivraj Hariram / Thombre, Dipalee / Shelar, Amruta / Gosavi, Krithika / Sangshetti, Jaiprakash / Zhang, Weiping / Sieniawska, Elwira / Patil, Rajendra / Kai, Guoyin

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 4

    Abstract: In the present study, biogenic selenium nanoparticles (SeNPs) have been prepared ... ...

    Abstract In the present study, biogenic selenium nanoparticles (SeNPs) have been prepared using
    MeSH term(s) Humans ; Antifungal Agents/pharmacology ; Nystatin/pharmacology ; Selenium/chemistry ; Candida albicans ; Nanoconjugates ; Nanoparticles/chemistry ; Biofilms
    Chemical Substances Antifungal Agents ; Nystatin (1400-61-9) ; Selenium (H6241UJ22B) ; Nanoconjugates
    Language English
    Publishing date 2023-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28041836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Green Synthesis of Silver Nanoparticles Using the

    Pungle, Rohini / Nile, Shivraj Hariram / Makwana, Nilesh / Singh, Ragini / Singh, Rana P / Kharat, Arun S

    Oxidative medicine and cellular longevity

    2022  Volume 2022, Page(s) 9671594

    Abstract: In this study, we report the green synthesis of silver nanoparticles (AgNPs) using the aqueous leaf extract ... ...

    Abstract In this study, we report the green synthesis of silver nanoparticles (AgNPs) using the aqueous leaf extract of
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Asteraceae ; Escherichia coli ; Humans ; Metal Nanoparticles/chemistry ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Silver/chemistry
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents ; Plant Extracts ; Silver (3M4G523W1G)
    Language English
    Publishing date 2022-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2455981-7
    ISSN 1942-0994 ; 1942-0994
    ISSN (online) 1942-0994
    ISSN 1942-0994
    DOI 10.1155/2022/9671594
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Horticultural oils: possible alternatives to chemical pesticides and insecticides.

    Nile, Arti Shivraj / Kwon, Young Deuk / Nile, Shivraj Hariram

    Environmental science and pollution research international

    2019  Volume 26, Issue 21, Page(s) 21127–21139

    Abstract: The farmers and agrochemical industries lack science-based knowledge about sustainable utilization of pesticides and insecticides. The investigation on rising use of chemical pesticides and insecticides has remarkable issue related to environment ... ...

    Abstract The farmers and agrochemical industries lack science-based knowledge about sustainable utilization of pesticides and insecticides. The investigation on rising use of chemical pesticides and insecticides has remarkable issue related to environment pollution, soil fertility, and human health; as such, nowadays, many people prefer natural alternatives over synthetic chemicals. Natural products, like horticultural oils, play a significant role for sustainable and safe integrated pest management, providing natural alternatives to chemical pesticides and insecticides. For several decades, both plant- and petroleum-based spray oils have been always used to control various pests, mites, and insects. Currently, these horticultural oils are used as a part of the integrated pest management, which utilizes secure and non-chemical pesticides rather than conventional pesticides. Horticultural oil refers to a complex mixture of hydro-carbons with traces of sulfur- and nitrogen-based compounds, extracted from plants. The key components of horticultural oils include paraffin and olefin. The horticultural oils are considered suitable since they are non-toxic to both plants and animals, are applied easily, have low risk properties, cost-effective, and play significant role in pest control, but show little effects on the beneficial insects. As a result, these attributes make horticultural oils to be considered as secure and effective alternative for chemical insecticides and pesticides for both commercial and domestic agriculture.
    MeSH term(s) Agriculture ; Animals ; Farmers ; Food ; Humans ; Insecta ; Insecticides/analysis ; Pest Control/methods ; Pesticides ; Plant Oils ; Plants ; Soil
    Chemical Substances Insecticides ; Pesticides ; Plant Oils ; Soil
    Language English
    Publishing date 2019-05-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-019-05509-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Green synthesis and characterization of Solanum xanthocarpum capped silver nanoparticles and its antimicrobial effect on multidrug-resistant bacterial (MDR) isolates.

    Pungle, Rohini / Nile, Shivraj Hariram / Kharat, Arun S

    Chemical biology & drug design

    2021  Volume 101, Issue 3, Page(s) 469–478

    Abstract: Plant extracts and their bioactive compounds are considered as the promising options for green synthesis of nanoparticles instead expensive and hazardous materials. Here, Solanum xanthocarpum fruit was used for synthesis of silver nanoparticles (AgNP). ... ...

    Abstract Plant extracts and their bioactive compounds are considered as the promising options for green synthesis of nanoparticles instead expensive and hazardous materials. Here, Solanum xanthocarpum fruit was used for synthesis of silver nanoparticles (AgNP). The synthesized AgNPs were characterized by using chromatographic and spectroscopic analytical methods. AgNPs were confirmed by UV-visible absorbance at 420-470 nm. TEM analysis showed AgNP with 22.45 nm average size. X-ray diffraction studies revealed the crystalline and face central cubic nature of AgNPs. FTIR analysis revealed functional group present over AgNPs. The aminodiphenyl acetic acid, clomipramine, and fonisopril from fruit extracts were found to be major capping agents on AgNPs as a result of analysis by HRLC-MS. All clinical isolates showed resistance for ampicilline, amoxyclav, niladixic acid, and sulphafurazole, suggesting multidrug resistance. The results showed that all isolates were sensitive to AgNPs synthesized fruit extracts. On the contrary, all isolates were resistant to whole S. xanthocarpum fruit extracts alone. The antimicrobial activity of AgNP was explored against multidrug-resistant (MDR) Gram-negative clinical isolates including Escherichia coli, Shigella spp., Aeronomonas spp. and Pseudomonas spp. MIC values ranged between 1.25 mg/ml and 2.5 mg/ml at 8 McFarland's standards. Minimum bactericidal concentration was found to be in between 2.5 mg/ml to 5 mg/ml. Nanoparticles synthesized from fruit extract of S. xanthocarpum containing aminodiphenyl acetic acid, clomipramine, and fonisopril metabolites exhibit promising antimicrobial activity against MDR Gram-negative clinical isolates.
    MeSH term(s) Anti-Bacterial Agents/chemistry ; Solanum/chemistry ; Silver/pharmacology ; Silver/chemistry ; Metal Nanoparticles/chemistry ; Clomipramine ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Microbial Sensitivity Tests ; Spectroscopy, Fourier Transform Infrared
    Chemical Substances Anti-Bacterial Agents ; Silver (3M4G523W1G) ; Clomipramine (NUV44L116D) ; Plant Extracts
    Language English
    Publishing date 2021-10-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2216600-2
    ISSN 1747-0285 ; 1747-0277
    ISSN (online) 1747-0285
    ISSN 1747-0277
    DOI 10.1111/cbdd.13945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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