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  1. Article ; Online: The effectiveness of psychiatric genetic counseling training: An analysis of 13 international workshops.

    Mack, Tiera / Batallones, Rolan / Morris, Emily / Inglis, Angela / Moldovan, Ramona / McGhee, Kevin / Zimmerman, Kip D / Austin, Jehannine

    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

    2024  , Page(s) e32978

    Abstract: Studies have consistently shown that psychiatric genetic counseling (pGC) helps people with psychiatric conditions by increasing empowerment and self-efficacy, and addressing emotions like guilt. Yet, it is not routinely provided. Genetic counselors and ... ...

    Abstract Studies have consistently shown that psychiatric genetic counseling (pGC) helps people with psychiatric conditions by increasing empowerment and self-efficacy, and addressing emotions like guilt. Yet, it is not routinely provided. Genetic counselors and trainees express low confidence in their ability to provide meaningful pGC, especially in the absence of adequate training. Therefore, to address this gap a "Psychiatric Genetic Counseling for Genetic Counselors" (PG4GC) workshop was developed and delivered to 13 groups of participants (primarily qualified genetic counselors and trainees) between 2015 and 2023 (10 workshops were delivered in-person, and three virtually). Participants completed quantitative questionnaires both before and after completing the workshop to assess their comfort, knowledge, behavior, and feeling of being equipped to provide pGC. In total, 232 individuals completed the pre-workshop questionnaire and 154 completed the post-workshop questionnaire. Participants felt more comfortable, knowledgeable, and equipped to provide pGC, and reported being more likely to address psychiatric concerns after the workshop, regardless of whether they were trainees or practicing professionals and whether they completed the workshop in-person or virtually. This study suggests that the PG4GC workshop is an effective educational tool in pGC training that may aid in broader implementation of the service.
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2108616-3
    ISSN 1552-485X ; 1552-4841 ; 0148-7299
    ISSN (online) 1552-485X
    ISSN 1552-4841 ; 0148-7299
    DOI 10.1002/ajmg.b.32978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 Vaccination and The Eye.

    Wang, Michael T M / Niederer, Rachael L / McGhee, Charles N J / Danesh-Meyer, Helen V

    American journal of ophthalmology

    2022  Volume 240, Page(s) 79–98

    Abstract: Purpose: To summarize the current evidence on COVID-19 vaccine-associated ocular adverse events.: Design: Narrative literature review.: Methods: The literature search was conducted in August 2021 using 4 electronic databases: MEDLINE, EMBASE, ... ...

    Abstract Purpose: To summarize the current evidence on COVID-19 vaccine-associated ocular adverse events.
    Design: Narrative literature review.
    Methods: The literature search was conducted in August 2021 using 4 electronic databases: MEDLINE, EMBASE, PubMed, and the Cochrane Database of Systematic Reviews. Population-based pharmacovigilance surveillance data were retrieved from all governmental agencies participating in the World Health Organization (WHO) Programme for International Drug Monitoring with publicly available online adverse event databases in English.
    Results: A small number of case reports have documented uveitis flares and acute corneal graft rejection occurring within the first 3 weeks following immunization, while isolated cases of optic neuropathies, retinal conditions, scleritis, and herpetic eye disease have also been highlighted. However, data from population-based pharmacovigilance surveillance systems suggest that the prevalence of vaccination-associated ocular adverse events are very rare.
    Conclusions: Vaccination-associated ocular adverse events are rare, and there is currently no substantive evidence to counterweigh the overwhelming benefits of COVID-19 immunization in patients with pre-existing ophthalmic conditions.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Population Surveillance ; Vaccination/adverse effects
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-02-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2022.02.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparison of Ectasia Detection in Early Keratoconus Using Scheimpflug-Based Corneal Tomography and Biomechanical Assessments.

    Wallace, Henry B / Vellara, Hans R / Gokul, Akilesh / McGhee, Charles N J / Meyer, Jay J

    Cornea

    2023  Volume 42, Issue 12, Page(s) 1528–1535

    Abstract: ... tomography (VAE-NT, n = 21) was assessed. Statistical analyses were completed with R software using t ...

    Abstract Purpose: The aim of this study was to determine the detection of keratoconus using corneal biomechanical parameters only, a corneal tomographic parameter only, and a parameter that combines corneal biomechanical and tomographic indices.
    Methods: The discriminatory power of the Pentacam Random Forest Index (PRFI), Belin/Ambrósio Enhanced Ectasia Display (BAD-D) index, Corvis Biomechanical Index (CBI), and Tomographic and Biomechanical Index (TBI) to differentiate between normal eyes (n = 84), eyes with very asymmetric corneal ectasia (VAE-E, n = 21), and the fellow eyes without apparent ectasia based on normal tomography (VAE-NT, n = 21) was assessed. Statistical analyses were completed with R software using t -tests, Wilcoxon rank sum tests, and receiver operating characteristic (ROC) curves. The DeLong test was used to compare the area under the ROC curve (AUROC).
    Results: The TBI and PRFI had the highest AUROC when distinguishing between normal and VAE-E corneas (AUROC = 1.00, 95% CI = 1.00-1.00); however, they were not statistically superior to the CBI (AUROC = 0.97, P = 0.27) or BAD-D (AUROC = 1.00, P = 0.34). The TBI (AUROC = 0.92, 95% CI = 0.86-0.98) was superior to CBI (AUROC = 0.78, P = 0.02) and BAD-D (AUROC = 0.81, P = 0.02) when distinguishing between healthy and VAE-NT corneas. At a threshold of 0.72, the TBI had 99% sensitivity, 67% specificity, and 92% accuracy in distinguishing normal and VAE-NT corneas.
    Conclusions: The TBI is a useful parameter for the screening of subclinical and frank keratoconus in tomographically normal eyes.
    MeSH term(s) Humans ; Keratoconus/diagnosis ; Corneal Topography/methods ; Dilatation, Pathologic/diagnosis ; Corneal Pachymetry ; Retrospective Studies ; Cornea ; ROC Curve ; Tomography ; Biomechanical Phenomena
    Language English
    Publishing date 2023-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000003273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: COVID-19: Surgical masks and respirators in the operating theatre.

    McGhee, J T / Buckley, J C / Gannon, M / Waterston, S

    The British journal of surgery

    2020  Volume 107, Issue 10, Page(s) e438

    MeSH term(s) COVID-19/prevention & control ; Equipment Design ; Humans ; Infection Control/methods ; Masks ; Operating Rooms/organization & administration ; Respiratory Protective Devices ; SARS-CoV-2 ; United Kingdom
    Keywords covid19
    Language English
    Publishing date 2020-08-01
    Publishing country England
    Document type Letter
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.11888
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Assessment of Health Disparities and Barriers to Accessing Keratoconus and Crosslinking at a Tertiary Referral Center.

    Angelo, Lize / Gokul, Akilesh / Wadhwa, Himanshu / McGhee, Charles N J / Ziaei, Mohammed

    Cornea

    2023  Volume 43, Issue 3, Page(s) 277–284

    Abstract: ... independent t tests, Pearson correlation, independent samples ANOVA, MANCOVA, and binomial logistic regression ...

    Abstract Purpose: The aim of this study was to determine the barriers to accessing the crosslinking service in Auckland, New Zealand.
    Methods: This was a prospective 1-year study of patients at Auckland District Health Board. Studied parameters included age, sex, body mass index, ethnicity, New Zealand Deprivation (NZDep; an area-based measure of socioeconomic status, 1 = low deprivation-10 = high deprivation) score of residence, disease severity (maximum keratometry and thinnest corneal thickness), attendance, distance travelled, car ownership, employment status, and visual outcomes. Statistical analysis was performed using independent t tests, Pearson correlation, independent samples ANOVA, MANCOVA, and binomial logistic regression.
    Results: Four hundred fifty-four patients with keratoconus were analyzed and had a mean age of 24.1 ± 0.8 years, mean body mass index of 33.0 ± 9.7 kg/m 2 , and 43% were female. Pacific Peoples consisted 40.2% of the population; Māori 27.2%; Europeans 21.2%; Asian 9.9%; and Middle Eastern, Latin American, and African (MELAA) 1.3%. The mean distance travelled was 12.5 ± 9.5 km, NZDep score was 6.8 ± 2.6, and attendance was 69.0 ± 42.5%. The lowest attendance was observed in Pacific Peoples (58.9%) and the highest was in Asians (90%) ( P = 0.019). The mean worst-eye visual acuity at attendance was 0.75 ± 0.47 logMAR (6/35). Unemployment was associated with worse best-eye visual acuity at FSA ( P = 0.01) and follow-up ( P < 0.05). Māori and Pacific Peoples had the highest NZDep ( P < 0.001), were younger at presentation ( P = 0.019), had higher disease severity ( P < 0.001), and worse visual acuity ( P < 0.001).
    Conclusions: Poor attendance was seen in this cohort. Pacific Peoples and Māori presented younger with worse disease severity and visual acuity but also had the highest nonattendance. These results suggest that deprivation, factors associated with ethnicity, and unemployment are potential barriers to attendance.
    MeSH term(s) Adult ; Female ; Humans ; Male ; Young Adult ; Health Inequities ; Keratoconus/diagnosis ; Keratoconus/epidemiology ; Keratoconus/ethnology ; Maori People ; New Zealand/epidemiology ; Prospective Studies ; Tertiary Care Centers ; Ethnicity/statistics & numerical data ; Health Services Accessibility/statistics & numerical data
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000003293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Screening interval for diabetic retinopathy: a personalised approach (abridged secondary publication).

    Lian, J / Lam, C L K / Thach, T Q / McGhee, S / Fung, C S C / Kwong, A S K / Chau, C K V / Chan, J C H

    Hong Kong medical journal = Xianggang yi xue za zhi

    2023  Volume 29 Suppl 3, Issue 3, Page(s) 33–35

    MeSH term(s) Humans ; Diabetic Retinopathy/diagnosis ; Diabetes Mellitus, Type 2/complications ; Mass Screening
    Language English
    Publishing date 2023-06-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 1239255-8
    ISSN 1024-2708
    ISSN 1024-2708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Improving Ad Hoc Medical Team Performance with an Innovative “I START-END” Communication Tool

    McGhee I / Tarshis J / DeSousa S

    Advances in Medical Education and Practice, Vol Volume 13, Pp 809-

    2022  Volume 820

    Abstract: ... caPurpose: To study the effect of a communication tool entitled: “I START-END” (I-Identify; S-Story; T-Task ... A-Accomplish/Adjust; R-Resources; T-Timely Updates; E-Exit; N-Next; D-Document and Debrief) in simulated urgent ... Irene McGhee,1 Jordan Tarshis,1 Susan DeSousa2 1Department of Anesthesiology, Sunnybrook Health ...

    Abstract Irene McGhee,1 Jordan Tarshis,1 Susan DeSousa2 1Department of Anesthesiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 2Sunnybrook Canadian Simulation Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, CanadaCorrespondence: Irene McGhee, Email irene.mcghee@utoronto.caPurpose: To study the effect of a communication tool entitled: “I START-END” (I-Identify; S-Story; T-Task; A-Accomplish/Adjust; R-Resources; T-Timely Updates; E-Exit; N-Next; D-Document and Debrief) in simulated urgent scenarios in non-operating room settings (referred to as “Ad Hoc”) with anesthesia residents. The “I START-END” tool was created by incorporating Crisis Resource Management (CRM) principles into a practical and user-friendly format.Methods: This was a mixed methods pre/post observational study with 47 anesthesia resident volunteers participating from July 2014 to June 2016. Each resident served as their own control, and participated in three simulated Ad Hoc scenarios. The first simulation served as a baseline. The second simulation occurred 1– 2 weeks after I START-END training. The third simulation occurred 3– 6 months later. Simulation performance was videotaped and reviewed by trained experts using technical skill checklists and Anesthesia Non-Technical Skills (ANTS) score. Residents filled out questionnaires, pre-simulation, 1– 2 weeks after I START-END training and 3– 6 months later. Concurrently, resident performance at actual Code Blue events was scored by trained observers using the Mayo High Performance Teamwork Scale.Results: 80– 90% of residents stated the tool provided an organized approach to Ad Hoc scenarios – specifically, information helpful to care of the patient was obtained more readily and better resource planning occurred as communication with the team improved. Residents stated they would continue to use the tool and apply it to other clinical settings. Resident video performance scores of technical skills showed significant improvement at the “late” session (3– 6 months post ...
    Keywords “ad hoc” teams ; team building ; i start-end tool ; non-operating room anesthesia ; crisis resource management ; team communication ; Special aspects of education ; LC8-6691 ; Medicine (General) ; R5-920
    Subject code 690
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher Dove Medical Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Do We Become More Lonely With Age? A Coordinated Data Analysis of Nine Longitudinal Studies.

    Graham, Eileen K / Beck, Emorie D / Jackson, Kathryn / Yoneda, Tomiko / McGhee, Chloe / Pieramici, Lily / Atherton, Olivia E / Luo, Jing / Willroth, Emily C / Steptoe, Andrew / Mroczek, Daniel K / Ong, Anthony D

    Psychological science

    2024  , Page(s) 9567976241242037

    Abstract: Loneliness is a pervasive experience with adverse impacts on health and well-being. Despite its significance, notable gaps impede a full understanding of how loneliness changes across the adult life span and what factors influence these changes. To ... ...

    Abstract Loneliness is a pervasive experience with adverse impacts on health and well-being. Despite its significance, notable gaps impede a full understanding of how loneliness changes across the adult life span and what factors influence these changes. To address this, we conducted a coordinated data analysis of nine longitudinal studies encompassing 128,118 participants ages 13 to 103 from over 20 countries. Using harmonized variables and models, we examined loneliness trajectories and predictors. Analyses revealed that loneliness follows a
    Language English
    Publishing date 2024-04-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2022256-7
    ISSN 1467-9280 ; 0956-7976
    ISSN (online) 1467-9280
    ISSN 0956-7976
    DOI 10.1177/09567976241242037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Social Capital and Autism in Young Adulthood: Applying Social Network Methods to Measure the Social Capital of Autistic Young Adults.

    McGhee Hassrick, Elizabeth / Sosnowy, Collette / Graham Holmes, Laura / Walton, Jessica / Shattuck, Paul T

    Autism in adulthood : challenges and management

    2020  Volume 2, Issue 3, Page(s) 243–254

    Abstract: Social isolation is a core challenge associated with autism. Interpersonal relationships and the resources and support embedded in the social networks of autistic young adults could impact key adult outcomes, including quality of life, mental health, ... ...

    Abstract Social isolation is a core challenge associated with autism. Interpersonal relationships and the resources and support embedded in the social networks of autistic young adults could impact key adult outcomes, including quality of life, mental health, employment, and independence. However, little research systematically measures the networks of autistic young adults and network impact on key adult outcomes. This article demonstrates how social network analysis can be adapted for the field of autism to measure young adult networks. We provide examples as to how this approach could be implemented to yield key insights into the amount and quality of interpersonal relationships and the types of resources embedded in the networks of autistic young adults. The network protocol was feasibility tested with autistic adults during the posthigh school transition period (
    Language English
    Publishing date 2020-09-03
    Publishing country United States
    Document type Journal Article
    ISSN 2573-959X
    ISSN (online) 2573-959X
    DOI 10.1089/aut.2019.0058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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