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  1. Article: COVID-19: Where We Are and Where We Are Going.

    Abenavoli, Ludovico / Gentile, Ivan

    Diseases (Basel, Switzerland)

    2023  Volume 11, Issue 1

    Abstract: The impact of COVID-19 on global health has been colossal [ ... ]. ...

    Abstract The impact of COVID-19 on global health has been colossal [...].
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2720869-2
    ISSN 2079-9721
    ISSN 2079-9721
    DOI 10.3390/diseases11010040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19

    Ludovico Abenavoli / Ivan Gentile

    Diseases, Vol 11, Iss 40, p

    Where We Are and Where We Are Going

    2023  Volume 40

    Abstract: The impact of COVID-19 on global health has been colossal [.] ...

    Abstract The impact of COVID-19 on global health has been colossal [.]
    Keywords n/a ; Medicine ; R
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Personalized care approaches to hepatitis C therapy: recent advances and future directions.

    Schiano Moriello, Nicola / Pinchera, Biagio / Gentile, Ivan

    Expert review of anti-infective therapy

    2024  Volume 22, Issue 4, Page(s) 139–151

    Abstract: Introduction: The introduction of direct-acting antivirals (DAAs) has significantly transformed the therapeutic landscape for chronic C hepatitis virus (HCV) infection. However, there is still room for further improvement in optimizing therapy efficacy ... ...

    Abstract Introduction: The introduction of direct-acting antivirals (DAAs) has significantly transformed the therapeutic landscape for chronic C hepatitis virus (HCV) infection. However, there is still room for further improvement in optimizing therapy efficacy and minimizing adverse effects.
    Areas covered: This review is devoted to the rationale for adopting a personalized approach to HCV therapy. Specifically, we explore the role of host-related factors, such as sex or the presence of comorbidities. We thoroughly examine the implications of commonly encountered comorbidities, including HIV infection, chronic renal disease, liver cirrhosis, and other chronic viral hepatitis infections. Additionally, we discuss the prevalent drug-to-drug interactions between DAAs and other medications, while providing guidance on their management. Finally, we investigate viral-related issues that can influence treatment outcomes, such as viral genotype, quasi-species, and the presence of resistance-associated mutations.
    Expert opinion: Despite pivotal trials demonstrating efficacy rates exceeding 90% for currently available DAA regimens, there are still opportunities to optimize therapy outcomes and tailor treatment to each patient. This can be achieved through a meticulous evaluation of the patient's specific clinical conditions and comorbidities, a vigilant approach to manage potential drug interactions, and diligent patient follow-up.
    MeSH term(s) Humans ; Antiviral Agents/adverse effects ; HIV Infections/drug therapy ; Hepatitis C, Chronic/drug therapy ; Hepatitis C/drug therapy ; Hepacivirus/genetics
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2024-03-11
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2024.2328336
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6106: Show issues Location:
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  4. Article ; Online: COVID-19 prophylaxis in immunosuppressed patients: Beyond vaccination.

    Gentile, Ivan / Schiano Moriello, Nicola

    PLoS medicine

    2022  Volume 19, Issue 1, Page(s) e1003917

    Abstract: Ivan Gentile and Nicola Schiano Moriello discuss the potential of monoclonal antibody prophylaxis ...

    Abstract Ivan Gentile and Nicola Schiano Moriello discuss the potential of monoclonal antibody prophylaxis against COVID-19 infection in immunocompromised patients.
    MeSH term(s) Antibodies, Monoclonal/administration & dosage ; Antibodies, Viral/administration & dosage ; COVID-19/immunology ; COVID-19/prevention & control ; Humans ; Immunocompromised Host/immunology ; Pre-Exposure Prophylaxis/methods ; Vaccination/methods ; Vaccination/trends
    Chemical Substances Antibodies, Monoclonal ; Antibodies, Viral
    Language English
    Publishing date 2022-01-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2185925-5
    ISSN 1549-1676 ; 1549-1277
    ISSN (online) 1549-1676
    ISSN 1549-1277
    DOI 10.1371/journal.pmed.1003917
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Crushing riluzole tablets: evaluation of loss of powder and active principle in a home-simulation experiment.

    Casiraghi, Antonella / Gentile, Andrea / Marjanovic, Ivan / Chiò, Adriano

    Amyotrophic lateral sclerosis & frontotemporal degeneration

    2023  , Page(s) 1–7

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2705049-X
    ISSN 2167-9223 ; 2167-8421
    ISSN (online) 2167-9223
    ISSN 2167-8421
    DOI 10.1080/21678421.2023.2245860
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5874: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: COVID-19 prophylaxis in immunosuppressed patients

    Ivan Gentile / Nicola Schiano Moriello

    PLoS Medicine, Vol 19, Iss 1, p e

    Beyond vaccination.

    2022  Volume 1003917

    Abstract: Ivan Gentile and Nicola Schiano Moriello discuss the potential of monoclonal antibody prophylaxis ...

    Abstract Ivan Gentile and Nicola Schiano Moriello discuss the potential of monoclonal antibody prophylaxis against COVID-19 infection in immunocompromised patients.
    Keywords Medicine ; R
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: COVID-19: Perspectives on the Potential Novel Global Threat.

    Gentile, Ivan / Abenavoli, Ludovico

    Reviews on recent clinical trials

    2020  Volume 15, Issue 2, Page(s) 84–86

    MeSH term(s) COVID-19 ; Clinical Trials as Topic ; Communicable Disease Control/organization & administration ; Communicable Diseases, Emerging/epidemiology ; Communicable Diseases, Emerging/prevention & control ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Female ; Global Health ; Humans ; Male ; Pandemics/prevention & control ; Pandemics/statistics & numerical data ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Prevalence ; Risk Assessment ; World Health Organization
    Keywords covid19
    Language English
    Publishing date 2020-03-01
    Publishing country United Arab Emirates
    Document type Editorial ; Review
    ZDB-ID 2251879-4
    ISSN 1876-1038 ; 1574-8871
    ISSN (online) 1876-1038
    ISSN 1574-8871
    DOI 10.2174/1574887115999200228100745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6436: Show issues Location:
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  8. Article ; Online: Incidence of cerebral venous thrombosis and COVID-19 vaccination: possible causal effect or just chance?

    de Simone, Giovanni / Stranges, Saverio / Gentile, Ivan

    European heart journal. Cardiovascular pharmacotherapy

    2021  Volume 7, Issue 4, Page(s) e77–e78

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Humans ; Incidence ; SARS-CoV-2 ; Vaccination/adverse effects ; Venous Thrombosis/diagnosis ; Venous Thrombosis/epidemiology ; Venous Thrombosis/prevention & control
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-04-30
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2808613-2
    ISSN 2055-6845 ; 2055-6837
    ISSN (online) 2055-6845
    ISSN 2055-6837
    DOI 10.1093/ehjcvp/pvab036
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  9. Article ; Online: Pneumocystis jirovecii pneumonia in COVID-19: an overlooked clinical entity-Response to "Pneumocystis pneumonia risk among viral acute respiratory distress syndrome related or not to COVID 19".

    Buonomo, Antonio Riccardo / Viceconte, Giulio / Gentile, Ivan

    Critical care (London, England)

    2021  Volume 25, Issue 1, Page(s) 418

    MeSH term(s) COVID-19 ; Humans ; Pneumocystis carinii ; Pneumonia, Pneumocystis/complications ; Respiratory Distress Syndrome ; SARS-CoV-2
    Language English
    Publishing date 2021-12-06
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-021-03836-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5517: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Stenotrophomonas maltophilia

    Maraolo, Alberto Enrico / Licciardi, Federica / Gentile, Ivan / Saracino, Annalisa / Belati, Alessandra / Bavaro, Davide Fiore

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 5

    Abstract: Stenotrophomonas maltophilia: Materials: PubMed/MEDLINE and Embase were searched from inception to 30 November 2022. The primary outcome was all-cause mortality. Secondary outcomes included clinical failure, adverse events, and length of stay. A ... ...

    Abstract Stenotrophomonas maltophilia
    Materials: PubMed/MEDLINE and Embase were searched from inception to 30 November 2022. The primary outcome was all-cause mortality. Secondary outcomes included clinical failure, adverse events, and length of stay. A random effects meta-analysis was performed. This study was registered with PROSPERO (CRD42022321893).
    Results: Twenty-four studies, all retrospective, were included. A significant difference in terms of overall mortality was observed when comparing as a monotherapy TMP/SMX versus FQs (odds ratio (OR) 1.46, 95% confidence interval (CI) 1.15-1.86, I
    Conclusions: Against SM infections, FQs and, possibly, TDs seem to be reasonable alternative choices to TMP/SMX. Data from clinical trials are urgently needed to better inform therapeutic choices in this setting by also taking into account newer agents.
    Language English
    Publishing date 2023-05-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12050910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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