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  1. Article ; Online: The vasa vasorum of the large pulmonary vessels are involved in COVID-19

    Hubert Daisley Jr / Arlene Rampersad / Martina Daisley / Amit Ramdin / Oneka Acco / Farhaana Narinesingh / Ornella Humphrey / Errol James

    Autopsy and Case Reports, Vol

    2021  Volume 11

    Keywords Blood Vessels ; Coronavirus Infection ; Vasa Vasorum ; Medicine ; R ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher University of São Paulo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: COVID-19

    Hubert Daisley Jr / Arlene Rampersad / Martina Daisley / Amit Ramdin / Oneka Acco / Farhaana Narinesingh / Ornella Humphrey

    Autopsy and Case Reports, Vol

    a closer look at the pathology in two autopsied cases. Is the pericyte at the center of the pathological process in COVID-19?

    2021  Volume 11

    Abstract: We performed autopsies on two cases of COVID-19. The microcirculations of all organs were the site of the pathological findings. Thrombotic microangiopathy was found in the brain and also the kidneys. Vasculitis was also a feature of the autopsy findings, ...

    Abstract We performed autopsies on two cases of COVID-19. The microcirculations of all organs were the site of the pathological findings. Thrombotic microangiopathy was found in the brain and also the kidneys. Vasculitis was also a feature of the autopsy findings, together with portal triaditis of the liver. The major pathological findings in both cases were fibrin deposits. Within the lung, the fibrin deposits were observed in the alveolar microcirculation in sub-endothelial locations of capillaries, arterioles, post capillary venules, and the adventitia of larger vessels. These fibrin deposits in the lungs occurred at the sites where pericytes are located in these vessels. The pericyte with its high concentration of ACE-2 receptors and its procoagulant state may represent one of the primary sites of action of SARS-CoV-2. A review of pericytes in health and disease is undertaken. COVID-19 is a disease of the microcirculation.
    Keywords Microcirculation ; Pericytes ; Fibrin ; SARS virus ; Medicine ; R ; Internal medicine ; RC31-1245
    Subject code 630
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher University of São Paulo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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