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  1. Article ; Online: Integrin Alpha v Beta 6 (αvβ6) and Its Implications in Cancer Treatment.

    Brzozowska, Ewa / Deshmukh, Sameer

    International journal of molecular sciences

    2022  Volume 23, Issue 20

    Abstract: Integrins are necessary for cell adhesion, migration, and positioning. Essential for inducing signalling events for cell survival, proliferation, and differentiation, they also trigger a variety of signal transduction pathways involved in mediating ... ...

    Abstract Integrins are necessary for cell adhesion, migration, and positioning. Essential for inducing signalling events for cell survival, proliferation, and differentiation, they also trigger a variety of signal transduction pathways involved in mediating invasion, metastasis, and squamous-cell carcinoma. Several recent studies have demonstrated that the up- and down-regulation of the expression of αv and other integrins can be a potent marker of malignant diseases and patient prognosis. This review focuses on an arginine-glycine-aspartic acid (RGD)-dependent integrin αVβ6, its biology, and its role in healthy humans. We examine the implications of αVβ6 in cancer progression and the promotion of epithelial-mesenchymal transition (EMT) by contributing to the activation of transforming growth factor beta TGF-β. Although αvβ6 is crucial for proper function in healthy people, it has also been validated as a target for cancer treatment. This review briefly considers aspects of targeting αVβ6 in the clinic via different therapeutic modalities.
    MeSH term(s) Humans ; Integrin alphaV ; Aspartic Acid ; Integrins/metabolism ; Antigens, Neoplasm/metabolism ; Transforming Growth Factor beta/metabolism ; Neoplasms/therapy ; Oligopeptides ; Arginine ; Glycine
    Chemical Substances integrin alphavbeta6 ; Integrin alphaV ; Aspartic Acid (30KYC7MIAI) ; Integrins ; Antigens, Neoplasm ; Transforming Growth Factor beta ; Oligopeptides ; Arginine (94ZLA3W45F) ; Glycine (TE7660XO1C)
    Language English
    Publishing date 2022-10-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232012346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online ; E-Book: Progress in mycology

    Deshmukh, Sunil Kumar / Deshpande, Mukund V. / Satyanarayana, T.

    biology and biotechnological applications

    2022  

    Author's details edited by Tulasi Satyanarayana, Sunil Kumar Deshmukh and Mukund V. Deshpande
    Keywords Fungi ; Mycology ; Micologia ; Biotecnologia ; Biologia
    Subject code 579.5
    Language English
    Size 1 online resource (676 pages)
    Publisher Springer
    Publishing place Gateway East, Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-3307-X ; 9789811633065 ; 978-981-16-3307-2 ; 9811633061
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Fungal biopolymers and biocomposites

    Deshpande, Mukund V. / Sridhar, K. R. / Deshmukh, S. K.

    prospects and avenues

    2022  

    Author's details Sunil K. Deshmukh, Mukund V. Deshpande and Kandikere R. Sridhar, editors
    Keywords Fungi/Industrial applications ; Biopolymers ; Fongs ; Aplicacions industrials ; Biopolímers
    Subject code 572
    Language English
    Size 1 online resource (424 pages)
    Publisher Springer Nature Singapore Pte Ltd
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Note Description based upon print version of record.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-19-1000-6 ; 9789811909993 ; 978-981-19-1000-5 ; 9811909997
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online ; E-Book: Progress in Mycology

    Satyanarayana, T. / Deshmukh, S. K. / Deshpande, Mukund V.

    An Indian Perspective

    2021  

    Abstract: Indian mycologists have extensively studied various groups of fungi such as soil fungi, aquatic fungi, marine fungi, endophytic fungi, fungi associated with man and animals. Though several books on various aspects of fungi are published, this is the ... ...

    Author's details edited by Tulasi Satyanarayana, Sunil Kumar Deshmukh, Mukund V. Deshpande
    Abstract Indian mycologists have extensively studied various groups of fungi such as soil fungi, aquatic fungi, marine fungi, endophytic fungi, fungi associated with man and animals. Though several books on various aspects of fungi are published, this is the first account of the history and developments in mycology in India. It discusses at length various stages of development of mycology including both classical and biotechnological aspects. It begins with a historical account of Indian mycology, followed by a description of research on fossil fungi. Further chapters cover the latest updates on different taxonomic groups of fungi. A dedicated section describes the roles and applications of fungal endophytes. The book also includes research in other important areas such as mushrooms and wood rotting fungi. Different chapters are written by leading mycologists. This book is useful to students, teachers and researchers in botany, microbiology, biotechnology and life sciences, agriculture and industries using fungi to produce various valuable products.
    Keywords Fungi ; Mycology ; Microbiology ; Microbial populations ; Biomedical engineering ; Bioinformatics ; Microbial Communities ; Biomedical Engineering and Bioengineering ; Computational and Systems Biology
    Subject code 589.2
    Language English
    Size 1 online resource (660 pages)
    Edition 1st ed. 2021.
    Publisher Springer Nature Singapore ; Imprint: Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-2350-3 ; 981-16-2349-X ; 978-981-16-2350-9 ; 978-981-16-2349-3
    DOI 10.1007/978-981-16-2350-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article: A comparative study to evaluate the efficacy of spaced v/s daily electroconvulsive therapy in schizophrenia.

    Deshmukh, D K / Sethna, K J / Nagesh, R P / Haridas, R M / Patankar, S V

    Indian journal of psychiatry

    2011  Volume 22, Issue 4, Page(s) 366–367

    Language English
    Publishing date 2011-11-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 221523-8
    ISSN 0019-5545
    ISSN 0019-5545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2038: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Report on the VI International Conference 2022 on 'Ayurveda for cancer' held at Wagholi, Pune.

    Vasant Deshmukh, Vineeta

    Journal of Ayurveda and integrative medicine

    2024  Volume 15, Issue 1, Page(s) 100885

    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Clinical Conference
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2023.100885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Making of a perfectionist maxillofacial surgeon - path and ways.

    Deshmukh, Vijay

    National journal of maxillofacial surgery

    2022  Volume 13, Issue 2, Page(s) 163–164

    Language English
    Publishing date 2022-07-15
    Publishing country India
    Document type Editorial
    ZDB-ID 2653583-X
    ISSN 2229-3418 ; 0975-5950
    ISSN (online) 2229-3418
    ISSN 0975-5950
    DOI 10.4103/njms.njms_113_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Superficial large Basal cell carcinoma over face, reconstructed by v-y plasty.

    Deshmukh, Palak / Sharma, Yugal K / Dogra, Bharat B / Chaudhari, Nitin D

    Journal of cutaneous and aesthetic surgery

    2014  Volume 7, Issue 1, Page(s) 65–66

    Language English
    Publishing date 2014-02-22
    Publishing country India
    Document type Journal Article
    ZDB-ID 2461107-4
    ISSN 0974-5157 ; 0974-2077
    ISSN (online) 0974-5157
    ISSN 0974-2077
    DOI 10.4103/0974-2077.129992
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: A COMPARATIVE STUDY OF MMPI PROFILES OF PSYCHIATRIC PG's v/s MEDICAL PG's.

    Deshmukh, D K / Eswaran, S / Nagesh, R P / Mahajan, S

    Indian journal of psychiatry

    2011  Volume 22, Issue 3, Page(s) 298–300

    Abstract: MMPI profiles of 10 psychiatric PG's have been compared with 10 medical PG's. The findings are discussed statistically and otherwise. Both the groups fall within the range of normal. Some interesting findings are not unexpected, if a larger section of ... ...

    Abstract MMPI profiles of 10 psychiatric PG's have been compared with 10 medical PG's. The findings are discussed statistically and otherwise. Both the groups fall within the range of normal. Some interesting findings are not unexpected, if a larger section of population could be studied preferably over a span of few years.
    Language English
    Publishing date 2011-11-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 221523-8
    ISSN 0019-5545
    ISSN 0019-5545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2038: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  10. Article ; Online: Chemical shift assignment of dsRBD1 and dsRBD2 of Arabidopsis thaliana DRB3, an essential protein involved in RNAi-mediated antiviral defense.

    Paul, Jaydeep / Deshmukh, Mandar V

    Biomolecular NMR assignments

    2024  

    Abstract: As sessile organisms, plants need to counteract different biotic and abiotic stresses to survive. RNA interference provides natural immunity against various plant pathogens, especially against viral infections via inhibition of viral genome replication ... ...

    Abstract As sessile organisms, plants need to counteract different biotic and abiotic stresses to survive. RNA interference provides natural immunity against various plant pathogens, especially against viral infections via inhibition of viral genome replication or translation. In plants, DRB3, a multi-domain protein containing two N-terminal dsRNA binding domains (dsRBD), plays a vital role in RNA-directed DNA methylation of the geminiviral genome. Additionally, DRB3 arrests the replication of the viral genome in the viral replication complex of RNA viruses through a mechanism that has yet to be fully deciphered. Therefore, as a first step towards exploring the structural details of DRB3, we present a nearly complete backbone and side chain assignment of the two N-terminal dsRBD domains.
    Language English
    Publishing date 2024-04-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2388861-1
    ISSN 1874-270X ; 1874-2718
    ISSN (online) 1874-270X
    ISSN 1874-2718
    DOI 10.1007/s12104-024-10174-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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